Subarachnoid hemorrhage in rats: Effect of singular or sustained hemodilution with α-α diaspirin crosslinked hemoglobin on cerebral hypoperfusion

Critical Care Medicine

Volumn 27, Issue 5, 1999, Pages 972-977

  Cole, Daniel J ^a   Reynolds, Lowell W ^a   Nary, Jeffrey C ^a   Drummond, John C ^b,c   Patel, Piyush M ^b,c   Jacobsen, Wayne K ^a  

^a LOMA LINDA UNIVERSITY   (United States)

^b University of California   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Blood substitutes; Brain injury; Cerebral blood flow; Cerebral ischemia; Diaspirin crosslinked hemoglobin solution; Hematocrit; Hemodilution; Hemoglobin based oxygen carrier; Subarachnoid hemorrhage; Vasospasm

Indexed keywords

DIASPIRIN CROSSLINKED HEMOGLOBIN; IODOPHENAZONE C 14; SERUM ALBUMIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN PERFUSION; CISTERNA MAGNA; CONTROLLED STUDY; HEMATOCRIT; HEMODILUTION; HUMAN; HUMAN CELL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SUBARACHNOID HEMORRHAGE; VASOSPASM;

ANIMALS; ASPIRIN; BLOOD FLOW VELOCITY; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; HEMATOCRIT; HEMODILUTION; HEMOGLOBINS; MALE; PROSPECTIVE STUDIES; RANDOM ALLOCATION; RATS; RATS, INBRED SHR; SERUM ALBUMIN; SUBARACHNOID HEMORRHAGE; TIME FACTORS;

EID: 0032995793     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-199905000-00038     Document Type: Article

References (43)

1. 1. Kassell NF, Drake CG: Timing of aneurysm surgery. Neurosurgery 1982; 10:514-519
2. 2. Broderick JP, Brott TG, Duldner JE, et al: Initial and recurrent bleeding are the major causes of death following subarachnoid hemorrhage. Stroke 1994; 25:1342-1347
3. 3. Kassell NF, Torner JC, Haley EC Jr, et al: The international cooperative study on the timing of aneurysm surgery: Part 1. Overall management results. J Neurosurg 1990; 73:18-36
4. 4. Martin NA, Doberstein C, Zane C, et al: Posttraumatic cerebral arterial spasm: Transcranial Doppler ultrasound, cerebral blood flow, and angiographic findings. J Neurosurg 1992; 77:575-583
5. 5. Taneda M, Kataoka K, Akai F, et al: Traumatic subarachnoid hemorrhage as a predictable indicator of delayed ischemic symptoms. J Neurosurg 1996; 84:762-768
6. 6. Macdonald RL, Weir BKA: A review of hemoglobin and the pathogenesis of cerebral vasospasm. Stroke 1991; 22: 971-982
7. 7. Macdonald RL, Weir BKA, Saito K, et al: Etiology of cerebral vasospasm in primates. J Neurosurg 1991; 75: 415-424
8. 8. Mayberg MR, Okada T, Bark DH: The role of hemoglobin in arterial narrowing after subarachnoid hemorrhage. J Neurosurg 1990; 72:634-640
9. 9. Macdonald RL, Weir BK: Cerebral vasospasm and free radicals. Free Radic Biol Med 1994; 16:633-643
10. 10. Nagatani K, Masciopinto JE, Letarte PB, et al: The effect of hemoglobin and its metabolites on energy metabolism in cultured cerebrovascular smooth-muscle cells. J Neurosurg 1995; 82: 244-249
11. 11. Suzuki S, Takenaka K, Kassell NF, et al: Hemoglobin augmentation of interleukin-1b-induced production of nitric oxide in smooth-muscle cells. J Neurosurg 1994; 81:895-901
12. 12. Findlay JM, Macdonald RL, Weir BKA: Current concepts of pathophysiology and management of cerebral vasospasm following aneurysmal subarachnoid hemorrhage. Cerebrovasc Brain Metab Rev 1991; 3:336-361
13. 13. Awad IA, Carter LP, Spetzler RF, et al: Clinical vasospasm after subarachnoid hemorrhage: Response to hypervolemic hemodilution and arterial hypertension. Stroke 1987; 18:365-372
14. 14. Kassell NF, Peerless SJ, Durward QJ, et al: Treatment of ischemic deficits from vasospasm with intravascular volume expansion and induced arterial hypertension. Neurosurgery 1982; 11: 337-343
15. 15. Origitano TC, Wascher TM, Reichman OH, et al: Sustained increased cerebral blood flow with prophylactic hypertensive hypervolemic hemodilution ("triple-H" therapy) after subarachnoid hemorrhage. Neurosurgery 1990; 27:729-740
16. 16. Mori K, Arai H, Nakajima K, et al: Hemorheological and hemodynamic analysis of hypervolemic hemodilution therapy for cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Stroke 1995; 26:1620-1626
17. 17. Usami S, Chien S, Gregersen MI: Hemoglobin solution as a plasma expander: Effects on blood viscosity. Proc Soc Exp Biol Med 1971; 136:1232-1235
18. 18. Cole DJ, Drummond JC, Patel PM, et al: Effects of viscosity and oxygen content of cerebral blood flow in ischemic and normal rat brain. J Neurol Sci 1994; 124:15-20
19. 19. Cole DJ, Schell RM, Pryzbelski RJ, et al: Focal cerebral ischemia in rats: Effect of hemodilution with a-a cross-linked hemoglobin on CBF. J Cereb Blood Flow Metab 1992; 12:971-976
20. 20. Cole DJ, Schell RM, Drummond JC, et al: Focal cerebral ischemia in rats: Effect of hypervolemic hemodilution with diaspirin cross-linked hemoglobin versus albumin on brain injury and edema. Anesthesiology 1993; 78:335-342
21. 21. Regan RF, Panter SS: Neurotoxicity of hemoglobin in cortical cell culture. Neurosci Lett 1993; 153:219-222
22. 22. Regan RF, Panter SS: Hemoglobin potentiates excitotoxic injury in cortical cell culture. J Neurotrauma 1996; 13:223-231
23. 23. Alayash AI, Fratantoni JC, Bonaventura C, et al: Nitric oxide binding to human ferrihemoglobins cross-linked between either a or b subunits. Arch Biochem Biophys 1993; 303: 332-338
24. 24. Hino A, Tokuyama Y, Weir B, et al: Changes in endothelial nitric oxide synthase mRNA during vasospasm after subarachnoid hemorrhage in monkeys. Neurosurgery 1996; 39:562-568
25. a2). J Biol Chem 1986; 261:9929-9937
26. 26. Estep TN, Bechtel MK, Miller TJ, et al. Virus inactivation in hemoglobin solutions by heat. In: Blood Substitutes. Chang TMS, Geyer RP (Eds). New York, Marcel Dekker, 1989, pp 129-134
27. 27. Estep TN, Bechtel MK, Bush SL, et al: The purification of hemoglobin solutions by heating. Prog Clin Biol Res 1989; 319:325-336
28. 28. Solomon RA, Antunes JL, Chen RYZ, et al: Decrease in cerebral blood flow in rats after experimental subarachnoid hemorrhage: A new animal model. Stroke 1985; 16:58-64
29. 29. Keipert PE, Gomez CL, Gonzales A, et al: Diaspirin cross-linked hemoglobin: Tissue distribution and long-term excretion after exchange transfusion. J Lab Clin Med 1994; 123:701-711
30. 30. Verlooy J, Van Reempts J, Haseldonckx M, et al: The course of vasospasm following subarachnoid haemorrhage in rats: A vertebrobasilar angiographic study. Acta Neurochir (Wien) 1992; 117:48-52
31. 31. Delgado TJ, Brismar J, Svendgaard NA: Subarachnoid haemorrhage in the rat: Angiography and fluorescence microscopy of the major cerebral arteries. Stroke 1985; 16:595-601
32. 32. Sakurada O, Kennedy C, Jehle J, et al: Measurement of local cerebral blood flow with iodo-C-14-antipyrine. Am J Physiol 1978; 234:H59-66
33. 33. Cole DJ, Nary JC, Reynolds LW, et al: Experimental subarachnoid hemorrhage in rats: Effect of intravenous a-a diaspirin crosslinked hemoglobin on hypoperfusion and neuronal death. Anesthesiology 1997; 87:1486-1493
34. 34. Cole DJ, Nary JC, Drummond JC, et al: a-a diaspirin crosslinked hemoglobin, nitric oxide, and cerebral ischemic injury in rats. Artif Cells Blood Substit Immobil Biotechnol 1997; 25:141-152
35. 35. Wellum GR, Irvine TW, Zervas NT: Dose responses of cerebral arteries of the dog, rabbit, and man to human hemoglobin in vitro. J Neurosurg 1980; 53:486-490
36. 36. Samdani AF, Dawson TM, Dawson VL: Nitric oxide synthase in models of focal ischemia. Stroke 1997; 28:1283-1288
37. 37. Glower BR, Yamamoto T, Cain L, et al: Endothelial injury following experimental subarachnoid hemorrhage in rats: Effects on brain blood flow. Anat Rec 1994; 240:104-114
38. 38. Nathan C, Xie Q-W: Nitric oxide synthases: Roles, tolls, and controls. Cell 1994; 78:915-918
39. 39. Iadecola C, Zhang F, Xu S, et al: Inducible nitric oxide synthase gene expression in brain following cerebral ischemia. J Cereb Blood Flow Metab 1995; 15:378-384
40. 40. Hess JF, Fadare SO, Tolentino LSL, et al: The intravascular persistence of crosslinked human hemoglobin. In: Progress in Clinical and Biological Research (Red Cell: 7th Ann Arbor Conference). Brewer B (Ed). New York, Alan R Liss, 1989, pp 351-360
41. 41. Boullin DJ, Tagari P, du Boulay G, et al: The role of hemoglobin in the etiology of cerebral vasospasm: An in vivo study of baboons. J Neurosurg 1983; 59:231-236
42. 42. Aoki T, Takenaka K, Suzuki S, et al: The role of hemolysate in the facilitation of oxyhemoglobin-induced contraction in rabbit basilar arteries. J Neurosurg 1994; 81:261-266
43. 43. Matz P, Weinstein P, States B, et al: Subarachnoid injections of lysed blood induce the hsp70 stress gene and produce DNA fragmentation in focal areas of the rat brain. Stroke 1996; 27: 504-513