Characterization of Hb Djelfa [β98(FG5)Val→Ala] by DNA sequencing in a French Caucasian family

Hemoglobin

Volumn 23, Issue 1, 1999, Pages 73-77

  Lacan, P ^a   Aubry, M ^a   Francina, A ^a   Couprie, N ^b   Dementhon, L ^b   Becchi, M ^c  

^a EDOUARD HERRIOT HOSPITAL   (France)

^b LMM Laboratoire Marcel Merieux   (France)

^c CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; DNA; HEMOGLOBIN DJELFA; HEMOGLOBIN VARIANT; UNCLASSIFIED DRUG; VALINE;

ARTICLE; CAUCASIAN; CONTROLLED STUDY; DNA SEQUENCE; GENE MUTATION; GLOBIN GENE; HEMOGLOBIN DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; ISOELECTRIC FOCUSING;

EID: 0032995151     PISSN: 03630269     EISSN: None     Source Type: Journal    
DOI: 10.3109/03630269908996150     Document Type: Article

References (11)

1. Gacon, G., Wajcman, H., Labie, D., and Cosson, A.: A new unstable hemoglobin mutated in β98(FG5)Val→Ala: Hb Djelfa. FEBS Lett., 58:238-240, 1975.
2. Gacon, G., Krishnamoorthy, R., Wajcman, H., Labie, D., Tapon, J., and Cosson, A.: Hemoglobin Djelfa β98(FG5)Val→Ala: isolation and functional properties of the heme saturated form. Biochim. Biophys. Acta, 490:156-163, 1977.
3. 298(FG5)Val→Ala, each being observed for the second time. Hemoglobin, 13:193-197, 1989.
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7. Kister, J., Poyart, C., and Edelstein, S.J.: An expanded two-state allosteric model for interactions of human hemoglobin A with nonsaturating concentrations of 2,3-diphosphoglycerate. J. Biol. Chem., 262:12085-12091, 1987.
8. Carrell, R..W. and Kay, R.: A simple method for the detection of unstable haemoglobins. Br. J. Haematol., 23:615-619, 1972.
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10. Witkowska, H.E., Bitsch, F., and Shackleton, C.H.L.: Expediting rare variant hemoglobin characterization by combined HPLC/electrospray mass spectrometry. Hemoglobin, 17:227-242, 1993.
11. Jelkmann, W., and Bauer, C.: What is the best method to remove 2,3-diphosphoglycerate from hemoglobin? Anal. Biochem., 75:382-388, 1976.