Synthesis and nematocidal activity of diarylnonanoids related to malabaricones

Chemical and Pharmaceutical Bulletin

Volumn 47, Issue 1, 1999, Pages 37-43

  Hosoi, Shinzo ^f   Kiuchi, Fumiyuki ^a,f   Nakamura, Norio ^b,f   Imasho, Masaaki ^c,f   Ali, Mohammad Ahad ^d,f   Sasaki, Youhei ^f   Tanaka, Eriko ^f   Tsumamoto, Yoshiyuki ^f   Kondo, Kaoru ^e,f   Tsuda, Yoshisuke ^f  

^a KYOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF TOYAMA   (Japan)

^c TOYAMA CHEMICAL CO LTD   (Japan)

^d UNIVERSITY OF DHAKA   (Bangladesh)

^e Ishikawa Health Service Association   (Japan)

^f KANAZAWA UNIVERSITY   (Japan)

Author keywords

Diarylnonanoid; Diarylundecanoid; Malabaricone; Nematocidal activity; Structure activity relationship; Toxocara canis

Indexed keywords

1 (4 HYDROXYPHENYL) 9 PHENYLNONAN 1 ONE; MALABARICONE A; MALABARICONE C; NONANOIC ACID; PLANT EXTRACT; UNCLASSIFIED DRUG; UNDECANOIC ACID;

ANTIMICROBIAL ACTIVITY; ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; NEMATODE; NEMATODIASIS; NONHUMAN; TOXOCARA CANIS;

EID: 0032994866     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.47.37     Document Type: Article

References (13)

1. XIX of Studies on Crude Drugs Effective on Visceral Larva Migrans. Part XVIII: Kiuchi F., Nakamura N., Saitoh M., Komagome K., Hiramatsu H., Takimoto N., Akao N., Kondo K., Tsuda Y., Chem. Pharm. Bull., 45, 685-696 (1997).
2. a) Purushothaman K. K., Sarada A., Connolly J. D., J. Chem. Soc., Perkin Trans. 1, 1977, 587-588;
3. b) Cooray N. F., Jansz E. R., Wimalasena S., Wijesekera T. P., Nair B. M., Phytochemistry, 26, 3669-3371 (1987);
4. c) Kumar N. S., Herath H. M. T. B., Karnarate V., ibid., 27, 465-468 (1988);
5. d) Pinto M. M. M., Kijjioa A., Tantisewie B., Yoshida M., Gottlieb O. R., ibid., 27, 3988-3989 (1988).
6. Tsuda Y., Hosoi S., Goto Y., Chem. Pharm. Bull., 39, 18-22 (1991).
7. Nakamura N., Kiuchi F., Tsuda Y., Kondo K., Chem. Pharm. Bull., 36, 2685-2688 (1988).
8. Lopes L. M. X., Yoshida M., Gottlieb O. R., Phytochemistry, 21, 751-755 (1982).
9. Nematocidal activity against second-stage larva of Toxocara canis was determined as described previously [Kiuchi F., Miyashita N., Tsuda Y., Kondo K., Yoshimura H., Chem. Pharm. Bull., 35, 2880-2886 (1987)]. MLC was defined as the lowest concentration which gave a relative mobility (RM) after 24 h of incubation.
10. See Part XVIII.
11. Kiuchi F., Goto Y., Sugimoto N., Akao N., Kondo K., Tsuda Y., Chem. Pharm.Bull., 41, 1640-1643 (1993).
12. For the synthesis of arylheptanals and arylnonanals. see Part XVIII.
13. Dean F. M., Goodchild J., Houghton L. E., Martin J. A., Morton R. B., Parton B., Price A. W., Somvichien N., Tetrahedron Lett., 1966, 4153-4159.