glmM operon and methicillin-resistant glmM suppressor mutants in Staphylococcus aureus

Antimicrobial Agents and Chemotherapy

Volumn 43, Issue 2, 1999, Pages 240-245

  Glanzmann, Philipp ^a   Gustafson, John ^a,c   Komatsuzawa, Hithoshi ^b   Ohta, Kouji ^b   Berger Bächi, Brigitte ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b HIROSHIMA UNIVERSITY   (Japan)

^c CURTIN UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSAMINE; IMIPENEM; METICILLIN; OXACILLIN; PENICILLIN BINDING PROTEIN; PHOSPHOGLUCOMUTASE; TEICOPLANIN; VANCOMYCIN;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIOLYSIS; BACTERIUM MUTANT; CISTRON; GENE DISRUPTION; GENETIC COMPLEMENTATION; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; OPERON; PRIORITY JOURNAL; SUPPRESSOR GENE; TRANSCRIPTION INITIATION;

EID: 0032993693     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.43.2.240     Document Type: Article

References (34)

1. Beauregard, D. A., D. H. Williams, M. N. Gwynn, and D. J. C. Knowles. 1995. Dimerization and membrane anchors in extracellular targeting of vancomycin group antibiotics. Antimicrob. Agents Chemother. 39:781-785.
2. Berger-Bächi, B., L. Barberis-Maino, A. Strässle, and F. H. Kayser. 1989. FemA, a host-mediated factor essential for methicillin resistance in Staphylococcus aureus: molecular cloning and characterization. Mol. Gen. Genet. 219:263-269.
3. Berger-Bächi, B., and M. L. Kohler. 1983. A novel site on the chromosome of Staphylococcus aureus influencing the level of methicillin resistance: genetic mapping. FEMS Microbiol. Lett. 20:305-309.
4. Berger-Bächi, B., A. Strässle, J. E. Gustafson, and F. H. Kayser. 1992. Mapping and characterization of multiple chromosomal factors involved in methicillin resistance in Staphylococcus aureus. Antimicrob. Agents Chemother. 36:1367-1373.
5. Berger-Bächi, B., A. Strässle, and F. H. Kayser. 1986. Characterization of an isogenic set of methicillin-resistant and -susceptible mutants of Staphylococcus aureus. Eur. J. Clin. Microbiol. 5:697-701.
6. Brendel, V., and E. N. Trifonov. 1984. A computer algorithm for testing potential prokaryotic terminators. Nucleic Acids Res. 12:4411-4427.
7. Coyette, J., and J. M. Ghuysen. 1968. Structure of the cell wall of Staphylococcus aureus, strain Copenhagen. IX. Teichoic acid and phage adsorption. Biochemistry 7:2385-2389.
8. de Jonge, B. L. M., Y. S. Chang, D. Gage, and A. Tomasz. 1992. Peptidoglycan composition in heterogeneous Tn551 mutants of a methicillin-resistant Staphylococcus aureus strain. J. Biol. Chem. 267:11255-11259.
9. de Jonge, B. L. M., and A. Tomasz. 1993. Abnormal peptidoglycan produced in a methicillin-resistant strain of Staphylococcus aureus grown in the presence of methicillin: functional role for penicillin-binding protein 2A in cell wall synthesis. Antimicrob. Agents Chemother. 37:342-346.
10. de Lencastre, H., and A. Tomasz. 1994. Reassessment of the number of auxiliary genes essential for expression of high-level methicillin resistance in Staphylococcus aureus. Antimicrob. Agents Chemother. 38:2590-2598.
11. Fischer, W. 1990. Bacterial phosphoglycolipids and lipoteichoic acids, p. 123-234. In M. Kates (ed.), Glycolipids, phosphoglycolipids, and sulfoglycolipids. Plenum Press, New York, N.Y.
12. Fujimura, T., and K. Murakami. 1997. Increase of methicillin resistance in Staphylococcus aureus caused by deletion of a gene whose product is homologous to lytic enzymes. J. Bacteriol. 179:6294-6301.
13. Gaisford, W. C., and P. E. Reynolds. 1989. Methicillin resistance in Staphylococcus epidermidis. Relationship between the additional penicillin-binding protein and an attachment transpeptidase. Eur. J. Biochem. 185:211-218.
14. Gustafson, J., A. Strässle, H. Hächler, F. H. Kayser, and B. Berger-Bächi. 1994. The femC locus of Staphylococcus aureus required for methicillin resistance includes the glutamine synthetase operon. J. Bacteriol. 176:1460-1467.
15. Gustafson, J. E., B. Berger-Bächi, A. Strässle, and B. J. Wilkinson. 1992. Autolysis of methicillin-resistant and -susceptible Staphylococcus aureus. Antimicrob. Agents Chemother. 36:566-572.
16. Henze, U., T. Sidow, J. Wecke, H. Labischinski, and B. Berger-Bächi. 1993. Influence of femB on methicillin resistance and peptidoglycan metabolism in Staphylococcus aureus. J. Bacteriol. 175:1612-1620.
17. Ishiwa, H., and N. Tsuchida. 1984. New shuttle vectors for Escherichia coli and Bacillus subtilis. I. Construction and characterization of plasmid pHY460 with twelve unique cloning sites. Gene 32:129-134.
18. Jenni, R., and B. Berger-Bächi. 1998. Teichoic acid content in different lineages of Staphylococcus aureus NCTC8325. Arch. Microbiol. 170:171-178.
19. Jolly, L., S. W. Wu, J, Van Heijenoort, H. De Lencastre, D. Mengin Lecreuix, and A. Tomasz. 1997. The femR315 gene from Staphylococcus aureus, the interruption of which results in reduced methicillin resistance, encodes a phosphoglucosamine mutase. J. Bacteriol. 179:5321-5325.
20. Komatsuzawa, H., K. Ohta, M. Sugai, T. Fujiwara, J. Suzuki, B. Berger-Bächi, and H. Suginaka. Tn551-insertional inactivation of fmtB gene renders methicillin-resistant Staphylococcus aureus susceptible to oxacillin and Triton X-100. Submitted for publication.
21. Kreiswirth, B. N., S. Löfdahl, M. J. Bentley, M. O'Reilly, P. M. Schlievert, M. S. Bergdoll, and R. P. Novick. 1983. The toxic shock syndrome exotoxin structural gene is not detectably transmitted by a prophage. Nature 305:680-685.
22. Kullik, I., and P. Giachino. 1997. The alternative sigma factor sigma(b) in Staphylococcus aureus - regulation of the sigB operon in response to growth phase and heat shock. Arch. Microbiol. 167:151-159.
23. Maniatis, T., E. F. Fritsch, and J. E. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
24. Mengin-Lecreulx, D., and J. van Heijenoort. 1996. Characterization of the essential gene glmM encoding phosphoglucosamine mutase in Escherichia coli. J. Biol. Chem. 271:32-39.
25. Ornelas-Soares, A., H. de Lencastre, B. L. M. de Jonge, and A. Tomasz. 1994. Reduced methicillin resistance in a new Staphylococcus aureus transposon mutant that incorporates muramyl dipeptides into the cell wall peptidoglycan. J. Biol. Chem. 269:27246-27250.
26. Rejchlik, W. 1992. OLIGO X.01 primer analysis software. National Biosciences Inc., Plymouth, Minn.
27. Reynolds, P. E., and D. F. Brown. 1985. Penicillin-binding proteins of beta-lactam-resistant strains of Staphylococcus aureus. Effect of growth conditions. FEBS Lett. 192:28-32.
28. Roos, M. H. H. 1995. Das Murein von Staphylococcus aureus. Untersuchung des Einflusses von Antibiotikaresistenzdeterminanten auf die Feinstruktur des Peptidoglykan von Staphylococcus aureus. Ph.D. thesis. Freie Universität Berlin, Berlin, Germany.
29. Ryffel, C., A. Strässle, F. H. Kayser, and B. Berger-Bächi. 1994. Mechanisms of heteroresistance in methicillin-resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 38:724-728.
30. Storz, G, and S. Altuvia. 1994. OxyR regulon. Methods Enzymol. 234:217-223.
31. Strandén, A. M., K. Ehlert, H. Labischinski, and B. Berger-Bächi. 1997. Cell wall monoglycine cross-bridges and methicillin hypersusceptibility in a femAB null mutant of methicillin-resistant Staphylococcus aureus. J. Bacteriol. 179:9-16.
32. Strandén, A. M., M. Roos, and B. Berger-Bächi. 1996. Glutamine synthetase and heteroresistance in methicillin-resistant Staphylococcus aureus. Microb. Drug Resist. 2:201-207.
33. University of Wisconsin Genetics Computer Group. 1994. Program manual for the Wisconsin package, version 8. University of Wisconsin Genetics Computer Group, Madison.
34. Wu, S. W., H. De Lencastre, A. Sali, and A. Tomasz. 1996. A phosphoglucomutase-like gene essential for the optimal expression of methicillin resistance in Staphylococcus aureus: molecular cloning and DNA sequencing. Microb. Drug Resist. 2:277-286.