Herpesvirus ateles gene product Tio interacts with nonreceptor protein tyrosine kinases

Journal of Virology

Volumn 73, Issue 6, 1999, Pages 4631-4639

  Albrecht, Jens Christian ^a   Friedrich, Ute ^a   Kardinal, Christian ^b   Koehn, Jadranka ^a   Fleckenstein, Bernhard ^a   Feller, Stephan M ^b   Biesinger, Brigitte ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; MESSENGER RNA; PROTEIN TYROSINE KINASE; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; GENE SEQUENCE; GENE STRUCTURE; GENETIC VARIABILITY; HERPES VIRUS; HUMAN; HUMAN CELL; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; VIRUS GENE; VIRUS GENOME;

EID: 0032993631     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.6.4631-4639.1999     Document Type: Article

References (77)

1. Albrecht, J. C., and B. Fleckenstein. Unpublished data. GenBank accession no. AF083424.
2. Albrecht, J. C., J. Nicholas, D. Biller, K. R. Cameron, B. Biesinger, C. Newman, S. Wittmann, M. A. Craxton, H. Coleman, and B. Fleckenstein. 1992. Primary structure of the herpesvirus saimiri genome. J. Virol. 66:5047-5058.
3. Biesinger, B. Unpublished data.
4. Biesinger, B., I. Muller-Fleckenstcin, B. Simmer, G. Lang, S. Wittmann, E. Platzer, R. C. Desrosiers, and B. Fleckenstein. 1992. Stable growth transformation of human T lymphocytes by herpesvirus samiri. Proc. Natl. Acad. Sci. USA 89:3116-3119.
5. Biesinger, B., J. J. Trimble, R. C. Desrosiers, and B. Fleckenstein. 1990. The divergence between two oncogenic Herpesvirus saimiri strains in a genomic region related to the transforming phenotype. Virology 176:505-514.
6. Biesinger, B., A. Y. Tsygankov, H. Fickenscher, F. Emmrich, B. Fleckenstein, J. B. Bolen, and B. M. Broker. 1995. The product of the Herpesvirus saimiri open reading frame 1 (tip) interacts with T cell-specific kinase p56lck in transformed cells. J. Biol. Chem. 270:4729-4734.
7. Bolen, J. B., C. J. Thiele, M. A. Israel, W. Yonemoto, L. A. Lipsich, and J. S. Brugge. 1984. Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and transformation. Cell 38:767-777.
8. Caldwell, R. G., J. B. Wilson, S. J. Anderson, and R. Longnecker. 1998. Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals. Immunity 9:405-411.
9. Cantley, L. C., K. R. Auger, C. Carpenter, B. Duckworth, A. Graziani, R. Kapeller, and S. Soltoff. 1991. Oncogenes and signal transduction. Cell 64:281-302. (Erratum, 65:914-915, 1991.)
10. Cheng, S. H., R. Harvey, P. C. Espino, K. Semba, T. Yamamoto, K. Toyoshima, and A. E. Smith. 1988. Peptide antibodies to the human c-fyn gene product demonstrate pp59c-fyn is capable of complex formation with the middle-T antigen of polyomavirus. EMBO J. 7:3845-3855.
11. Courtneidge, S. A., and A. E. Smith. 1983. Polyoma virus transforming protein associates with the product of the c-src cellular gene. Nature 303: 435-439.
12. Daniel, M. D., L. V. Melendez, R. D. Hunt, N. W. King, M. Anver, C. E. Fraser, H. Barahona, and R. B. Baggs. 1974. Herpesvirus saimiri. VII. Induction of malignant lymphoma in New Zealand White rabbits. J. Natl. Cancer Inst. 53:1803-1807.
13. Desrosiers, R. C., A. Bakker, J. Kamine, L. A. Falk, R. D. Hunt, and N. W. King. 1985. A region of the Herpesvirus saimiri genome required for oncogenicity. Science 228:184-187.
14. Desrosiers, R. C., D. P. Silva, L. M. Waldron, and N. L. Letvin. 1986. Nononcogenic deletion mutants of herpesvirus saimiri are defective for in vitro immortalization. J. Virol. 57:701-705.
15. Dilworth, S. M., C. E. Brewster, M. D. Jones, L. Lanfrancone, G. Pelicci, and P. G. Pelicci. 1994. Transformation by polyoma virus middle T-antigen involves the binding and tyrosine phosphorylation of Shc. Nature 367:87-90.
16. DiMaio, D., C. C. Lai, and O. Klein. 1998. Virocrine transformation: the intersection between viral transforming proteins and cellular signal transduction pathways. Annu. Rev. Microbiol. 52:397-421.
17. Du, Z., S. M. Lang, V. G. Sasseville, A. A. Lackner, P. O. Ilyinskii, M. D. Daniel, J. U. Jung, and R. C. Desrosiers. 1995. Identification of a nef allele that causes lymphocyte activation and acute disease in macaque monkeys. Cell 82:665-674.
18. Duboise, S. M., J. Guo, S. Czajak, R. C. Desrosiers, and J. U. Jung. 1998. STP and Tip are essential for herpesvirus saimiri oncogenicity. J. Virol. 72:1308-1313.
19. Duboise, S. M., H. Lee, J. Guo, J. K. Choi, S. Czajak, M. Simon, R. C. Desrosiers, and J. U. Jung. 1998. Mutation of the Lck-binding motif of Tip enhances lymphoid cell activation by herpesvirus saimiri. J. Virol. 72:2607-2614.
20. DuBridge, R. B., P. Tang, H. C. Hsia, P. M. Leong, J. H. Miller, and M. P. Calos. 1987. Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system. Mol. Cell. Biol. 7:379-387.
21. Dunant, N. M., A. S. Messerschmitt, and K. Ballmer-Hofer. 1997. Functional interaction between the SH2 domain of Fyn and tyrosine 324 of hamster polyomavirus middle-T antigen. J. Virol. 71:199-206.
22. Dunant, N. M., M. Senften, and K. Ballmer-Hofer. 1996. Polyomavirus middle-T antigen associates with the kinase domain of Src-related tyrosine kinases. J. Virol. 70:1323-1330.
23. Ensser, A., R. Pflanz, and B. Fleckenstein. 1997. Primary structure of the alcelaphine herpesvirus 1 genome. J. Virol. 71:6517-6525.
24. Falk, L. A., S. M. Nigida, F. Deinhardt, L. G. Wolfe, R. W. Cooper, and J. I. Hernandez-Camacho. 1974. Herpesvirus ateles: properties of an oncogenic herpesvirus isolated from circulating lymphocytes of spider monkeys (Ateles sp.). Int. J. Cancer 14:473-482.
25. Feng, S., T. M. Kapoor, F. Shirai, A. P. Combs, and S. L. Schreiber. 1996. Molecular basis for the binding of SH3 ligands with non-peptide elements identified by combinatorial synthesis. Chem. Biol. 3:661-670.
26. Feng, S., C. Kasahara, R. J. Rickles, and S. L. Schreiber. 1995. Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands. Proc. Natl. Acad. Sci. USA 92:12408-12415.
27. Fickenscher, H., and B. Fleckenstein. 1994. Generation of human T-cell lines using lymphotropic herpesviruses. Methods Mol. Genet. 4:345-362.
28. Fleckenstein, B., and R. C. Desrosiers. 1982. Herpesvirus saimiri and herpesvirus ateles, p. 253-332. In B. Roizman (ed.), The herpesviruses, vol. 1. Plenum Press, New York, N.Y.
29. Fruehling, S., and R. Longnecker. 1997. The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction. Virology 235:241-251.
30. Fruehling, S., R. Swart, K. M. Dolwick, E. Kremmer, and R. Longnecker. 1998. Tyrosine 112 of latent membrane protein 2A is essential for protein tyrosine kinase loading and regulation of Epstein-Barr virus latency. J. Virol. 72:7796-7806.
31. Geck, P., S. A. Whitaker, M. M. Medveczky, and P. G. Medveczky. 1990. Expression of collagenlike sequences by a tumor virus, herpesvirus saimiri. J. Virol. 64:3509-3515. (Erratum, 65:7084, 1991.
32. Ghai, J., R. S. Ostrow, J. Tolar, R. C. McGlennen, T. D. Lemke, D. Tobolt, Z. Liu, and A. J. Faras. 1996. The E5 gene product of rhesus papillomavirus is an activator of endogenous Ras and phosphatidylinositol-3′-kinase in NIH 3T3 cells. Proc. Natl. Acad. Sci. USA 93:12879-12884.
33. Gu, Z., and G. Matlashewski. 1995. Effect of human papillomavirus type 16 oncogenes on MAP kinase activity. J. Virol. 69:8051-8056.
34. Guo, J., K. Williams, S. M. Duboise, L. Alexander, R. Veazey, and J. U. Jung. 1998. Substitution of ras for the herpesvirus saimiri STP oncogene in lymphocyte transformation. J. Virol. 72:3698-3704.
35. Heldin, C. H. 1995. Dimerization of cell surface receptors in signal transduction. Cell 80:213-223.
36. Horak, I. D., T. Kawakami, F. Gregory, K. C. Robbins, and J. B. Bolen. 1989. Association of p60fyn with middle tumor antigen in murine polyomavirus-transformed rat cells. J. Virol. 63:2343-2347.
37. Jung, J. U., J. K. Choi, A. Ensser, and B. Biesinger. Herpesvirus saimiri as a model for gammaherpesvirus oncogenesis. Semin. Cancer Biol., in press.
38. Jung, J. U., and R. C. Desrosiers. 1991. Identification and characterization of the herpesvirus saimiri oncoprotein STP-C488. J. Virol. 65:6953-6960.
39. Jung, J. U., and R. C. Desrosiers. 1995. Association of the viral oncoprotein STP-C488 with cellular ras. Mol. Cell. Biol. 15:6506-6512.
40. Jung, J. U., S. M. Lang, U. Friedrich, T. Jun, T. M. Roberts, R. C. Desrosiers, and B. Biesinger. 1995. Identification of Lck-binding elements in tip of herpesvirus saimiri. J. Biol. Chem. 270:20660-20667.
41. Jung, J. U., S. M. Lang, T. Jun, T. M. Roberts, A. Veillette, and R. C. Desrosiers. 1995. Downregulation of Lck-mediated signal transduction by tip of herpesvirus saimiri. J. Virol. 69:7814-7822.
42. Jung, J. U., J. J. Trimble, N. W. King, B. Biesinger, B. W. Fleckenstein, and R. C. Desrosiers. 1991. Identification of transforming genes of subgroup A and C strains of Herpesvirus saimiri. Proc. Natl. Acad. Sci. USA 88:7051-7055.
43. Kamine, J., A. Bakker, and R. C. Desrosiers. 1984. Mapping of RNA transcribed from a region of the herpesvirus saimiri genome required for oncogenicity. J, Virol. 52:532-540.
44. Koomey, J. M., C. Mulder, R. L. Burghof, B. Fleckenstein, and R. C. Desrosiers. 1984. Deletion of DNA sequence in a nononcogenic variant of herpesvirus saimiri. J. Virol. 50:662-665.
45. Kornbluth, S., M. Sudol, and H. Hanafusa. 1987. Association of the polyomavirus middle-T antigen with c-yes protein. Nature 325:171-173.
46. Kretschmer, C., C. Murphy, B. Biesinger, J. Beckers, H. Fickenscher, T. Kirchner, B. Fleckenstein, and U. Ruther. 1996. A Herpes saimiri oncogene causing peripheral T-cell lymphoma in transgenic mice. Oncogene 12:1609-1616.
47. Larose, L., G. Gish, S. Shoelson, and T. Pawson. 1993. Identification of residues in the beta platelet-derived growth factor receptor that confer specificity for binding to phospholipase C-gamma 1. Oncogene 8:2493-2499.
48. Lee, H., J. J. Trimble, D.-W. Yoon, D. Regler, R. C. Desrosiers, and J. U. Jung. 1997. Genetic variation of herpesvirus saimiri subgroup A transforming protein and its association with cellular src. J. Virol. 71:3817-3825.
49. Longnecker, R., and C. L. Miller. 1996. Regulation of Epstein-Barr virus latency by latent membrane protein 2. Trends Microbiol. 4:38-42.
50. Lund, T., M. M. Medveczky, and P. G. Medveczky. 1997. Herpesvirus saimiri Tip-484 membrane protein markedly increases p56lck activity in T cells. J. Virol. 71:378-382.
51. Lund, T., M. M. Medveczky, P. J. Neame, and P. G. Medveczky. 1996. A herpesvirus saimiri membrane protein required for interleukin-2 independence forms a stable complex with p56lck. J. Virol. 70:600-606.
52. Medveczky, M. M., P. Geck, J. L. Sullivan, D. Serbousek, J. Y. Djeu, and P. G. Medveczky. 1993. IL-2 independent growth and cytotoxicity of herpesvirus saimiri-infected human CD8 cells and involvement of two open reading frame sequences of the virus. Virology 196:402-412.
53. Medveczky, P., E. Szomolanyi, R. C. Desrosiers, and C. Mulder. 1984. Classification of herpesvirus saimiri into three groups based on extreme variation in a DNA region required for oncogenicity. J. Virol. 52:938-944.
54. Messerschmitt, A. S., N. Dunant, and K. Ballmer-Hofer. 1997. DNA tumor viruses and Src family tyrosine kinases, an intimate relationship. Virology 227:271-280.
55. Miller, C. L., A. L. Burkhardt, J. H. Lee, B. Stealey, R. Longnecker, J. B. Bolen, and E. Kieff. 1995. Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases. Immunity 2:155-166.
56. Murphy, C., C. Kretschmer, B. Biesinger, J. Beckers, J. Jung, R. C. Desrosiers, H. K. Muller-Hermelink, B. W. Fleckenstein, and U. Ruther. 1994. Epithelial tumours induced by a herpesvirus oncogene in transgenic mice. Oncogene 9:221-226.
57. Murthy, S. C., J. J. Trimble, and R. C. Desrosiers. 1989. Deletion mutants of herpesvirus saimiri define an open reading frame necessary for transformation. J. Virol. 63:3307-3314.
58. Neipel, F., J. C. Albrecht, and B. Fleckenstein. 1997. Cell-homologous genes in the Kaposi's sarcoma-associated rhadinovirus human herpesvirus 8: determinants of its pathogenicity? J. Virol. 71:4187-4192.
59. Noraz, N., K. Saha, F. Ottones, S. Smith, and N. Taylor. 1998. Constitutive activation of TCR signaling molecules in IL-2-independent Herpesvirus saimiri-transformed T cells. J. Immunol. 160:2042-2045.
60. Oehrl, W., C. Kardinal, S. Ruf, K. Adermann, J. Groffen, G. S. Feng, J. Blenis, T. H. Tan, and S. M. Feller. 1998. The germinal center kinase (GCK)-related protein kinases HPK1 and KHS are candidates for highly selective signal transducers of Crk family adapter proteins. Oncogene 17: 1893-1901.
61. Pallas, D. C., H. Fu, L. C. Haehnel, W. Weller, R. J. Collier, and T. M. Roberts. 1994. Association of polyomavirus middle tumor antigen with 14-3-3 proteins. Science 265:535-537.
62. Pallas, D. C., L. K. Shahrik, B. L. Martin, S. Jaspers, T. B. Miller, D. L. Brautigan, and T. M. Roberts. 1990. Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A. Cell 60:167-176.
63. Pear, W. S., G. P. Nolan, M. L. Scott, and D. Baltimore. 1993. Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl. Acad. Sci. USA 90:8392-8396.
64. Posera, G., J. Zheng, B. S. Knudsen, C. Kardinal, K. B. Muller, J. Voss, T. Shishido, D. Cowburn, G. Cheng, B. Wang, G. D. Kruh, S. K. Burrell, C. A. Jacobson, D. M. Lenz, T. J. Zamborelli, K. Adermann, H. Hanafusa, and S. M. Feller. 1998. Development of highly selective SH3 binding peptides for Crk and CRKL which disrupt Crk-complexes with DOCK180, SoS and C3G. Oncogene 16:1903-1912.
65. Ren, R., B. J. Mayer, P. Cicchetti, and D. Baltimore. 1993. Identification of a ten-amino acid proline-rich SH3 binding site. Science 259:1157-1161.
66. Richter, J., I. Puchtler, and B. Fleckenstein. 1988. Thymidylate synthase gene of herpesvirus ateles. J. Virol. 62:3530-3535.
67. Russo, J. J., R. A. Bohenzky, M. C. Chien, J. Chen, M. Yan, D. Maddalena, J. P. Parry, D. Peruzzi, I. S. Edelman, Y. Chang, and P. S. Moore. 1996. Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8). Proc. Natl. Acad. Sci. USA 93:14862-14867.
68. Senften, M., S. Dilworth, and K. Ballmer-Hofer. 1997. Multimerization of polyomavirus middle-T antigen. J. Virol. 71:6990-6995.
69. Songyang, Z., S. E. Shoelson, M. Chaudhuri, G. Gish, T. Pawson, W. G. Haser, F. King, T. Roberts, S. Ratnofsky, and R. J. Lechleider. 1993. SH2 domains recognize specific phosphopeptide sequences. Cell 72:767-778.
70. Songyang, Z., S. E. Shoelson, J. McGlade, P. Olivier, T. Pawson, X. R. Bustelo, M. Barbacid, H. Sabe, H. Hanafusa, and T. Yi. 1994. Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav. Mol. Cell. Biol. 14:2777-2785.
71. Su, W., W. Liu, B. S. Schaffhausen, and T. M. Roberts. 1995. Association of polyomavirus middle tumor antigen with phospholipase C-gamma 1. J. Biol. Chem. 270:12331-12334.
72. Szomolanyi, E., P. Medveczky, and C. Mulder. 1987. In vitro immortalization of marmoset cells with three subgroups of herpesvirus saimiri. J. Virol. 61:3485-3490.
73. Virgin, H. W., P. Latreille, P. Wamsley, K. Hallsworth, K. E. Week, A. J. Dal Canto, and S. H. Speck. 1997. Complete sequence and genomic analysis of murine gammaherpesvirus 68. J. Virol. 71:5894-5904.
74. Whitman, M., D. R. Kaplan, B. Schaffhausen, L. Cantley, and T. M. Roberts. 1985. Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation. Nature 315:239-242.
75. Wiese, N., A. Y. Tsygankov, U. Klauenberg, J. B. Bolen, B. Fleischer, and B. M. Broker. 1996. Selective activation of T cell kinase p561ck by Herpesvirus saimiri protein tip. J. Biol. Chem. 271:847-852.
76. Xu, W., S. C. Harrison, and M. J. Eck. 1997. Three-dimensional structure of the tyrosine kinase c-Src. Nature 385:595-602.
77. Yoon, D. W., H. Lee, W. Seol, M. DeMaria, M. Rosenzweig, and J. U. Jung. 1997. Tap: a novel cellular protein that interacts with tip of herpesvirus saimiri and induces lymphocyte aggregation. Immunity 6:571-582.