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Volumn 5, Issue 6, 1999, Pages 339-354

Changes in fecal flora and comparative multiple-dose pharmacokinetics of ceftibuten, cefpodoxime proxetil and amoxycillin/clavulanate

Author keywords

Amoxycillin clavulanate; Cefpodoxime proxetil; Ceftibuten; Fecal flora; Pharmacokinetics; Statistical analysis; Triple crossover design; lactamase activity

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; ANTIBIOTIC AGENT; BETA LACTAMASE; CEFPODOXIME PROXETIL; CEFTIBUTEN; CEPHALOSPORIN DERIVATIVE;

EID: 0032993364     PISSN: 1198743X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-0691.1999.tb00153.x     Document Type: Article
Times cited : (9)

References (69)
  • 1
    • 0344706727 scopus 로고
    • Cephalosporins
    • Gorbach SL, Bartlett JG, Blacklow NR, eds. Philadelphia, London, Toronto: WB Saunders Company, Harcourt Brace Jovanovich, Inc.
    • Moellering Jr RC, Sentochnik DE. Cephalosporins. In Gorbach SL, Bartlett JG, Blacklow NR, eds. Infectious diseases, 1st edn. Philadelphia, London, Toronto: WB Saunders Company, Harcourt Brace Jovanovich, Inc., 1992: 172-82.
    • (1992) Infectious Diseases, 1st Edn. , pp. 172-182
    • Moellering R.C., Jr.1    Sentochnik, D.E.2
  • 2
    • 0027193549 scopus 로고
    • Pharmacokinetics of new oral cephalosporins, including a new carbacepheme
    • Fassbender M, Lode H, Schaberg T, Borner K, Koeppe P. Pharmacokinetics of new oral cephalosporins, including a new carbacepheme. Clin Infect Dis 1993; 16: 646-53.
    • (1993) Clin Infect Dis , vol.16 , pp. 646-653
    • Fassbender, M.1    Lode, H.2    Schaberg, T.3    Borner, K.4    Koeppe, P.5
  • 3
    • 0001592153 scopus 로고
    • Ceftibuten: A review of antimicrobial activity, spectrum and other microbiologic features
    • Jones RN. Ceftibuten: a review of antimicrobial activity, spectrum and other microbiologic features. Pediatr Infect Dis J 1993; 12: S37-44.
    • (1993) Pediatr Infect Dis J , vol.12
    • Jones, R.N.1
  • 4
    • 0028298349 scopus 로고
    • Ceftibuten. A review of its antibacterial activity, pharmacokinetic properties and clinical efficacy
    • Wiseman LR, Balfour JA. Ceftibuten. A review of its antibacterial activity, pharmacokinetic properties and clinical efficacy. Drugs 1994; 47: 784-808.
    • (1994) Drugs , vol.47 , pp. 784-808
    • Wiseman, L.R.1    Balfour, J.A.2
  • 5
    • 0028287729 scopus 로고
    • Comparative pharmacokinetics of the new oral cephalosporins
    • Lode H, Fassbender M, Schaberg T, Borner K, Koeppe P. Comparative pharmacokinetics of the new oral cephalosporins. Drugs 1994; 47(suppl 3): 10-20.
    • (1994) Drugs , vol.47 , Issue.SUPPL. 3 , pp. 10-20
    • Lode, H.1    Fassbender, M.2    Schaberg, T.3    Borner, K.4    Koeppe, P.5
  • 6
    • 0010502180 scopus 로고
    • Ceftibuten: Minimal inhibitory concentrations, post-antibiotic effect, beta-lactamase stability - A rationale for dosing programs
    • Neu H. Ceftibuten: minimal inhibitory concentrations, post-antibiotic effect, beta-lactamase stability - a rationale for dosing programs. Pediatr Infect Dis J 1993; 12: S49-54.
    • (1993) Pediatr Infect Dis J , vol.12
    • Neu, H.1
  • 7
    • 0023808285 scopus 로고
    • In vitro evaluation of ceftibuten (7432-S; SCH 39720), a novel orally administered cephalosporin
    • Jones RN, Barry AL. In vitro evaluation of ceftibuten (7432-S; SCH 39720), a novel orally administered cephalosporin. Chemioterapia 1988; 7: 283-6.
    • (1988) Chemioterapia , vol.7 , pp. 283-286
    • Jones, R.N.1    Barry, A.L.2
  • 8
    • 0026013030 scopus 로고
    • Randomized comparative study of ceftibuten versus cefaclor in the treatment of acute lower respiratory infections
    • Kammer RB, Ress R. Randomized comparative study of ceftibuten versus cefaclor in the treatment of acute lower respiratory infections. Diagn Microbiol Infect Dis 1991; 14: 101-5.
    • (1991) Diagn Microbiol Infect Dis , vol.14 , pp. 101-105
    • Kammer, R.B.1    Ress, R.2
  • 9
    • 0031900739 scopus 로고    scopus 로고
    • In-vitro activity of 21 beta-lactam antibiotics against penicillin-susceptible and penicillin-resistant streptococcus pneumoniae
    • Verhaegen J, Verbist L. In-vitro activity of 21 beta-lactam antibiotics against penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae. J Antimicrob Chemother 1998; 41: 381-5.
    • (1998) J Antimicrob Chemother , vol.41 , pp. 381-385
    • Verhaegen, J.1    Verbist, L.2
  • 11
    • 0027742557 scopus 로고
    • Effect of ceftibuten on the normal intestinal microflora
    • Brismar B, Edlund C, Nord CE. Effect of ceftibuten on the normal intestinal microflora. Infection 1993; 21: 25-7.
    • (1993) Infection , vol.21 , pp. 25-27
    • Brismar, B.1    Edlund, C.2    Nord, C.E.3
  • 12
    • 0028353199 scopus 로고
    • Cefpodoxime proxetil: A comprehensive review
    • Todd WM. Cefpodoxime proxetil: a comprehensive review. Int Antimicrob Agents 1994; 4: 37-62.
    • (1994) Int Antimicrob Agents , vol.4 , pp. 37-62
    • Todd, W.M.1
  • 13
    • 0026440303 scopus 로고
    • Cefpodoxime proxetil. A review of its antibacterial activity, pharmacokinetic properties and therapeutic potential
    • Frampton JE, Brogden RN, Langtry HD, Buckley MN. Cefpodoxime proxetil. A review of its antibacterial activity, pharmacokinetic properties and therapeutic potential. Drugs 1992; 44: 889-917.
    • (1992) Drugs , vol.44 , pp. 889-917
    • Frampton, J.E.1    Brogden, R.N.2    Langtry, H.D.3    Buckley, M.N.4
  • 14
    • 0026336293 scopus 로고
    • Review of clinical experience in the United States with cefpodoxime proxetil in adults, with uncomplicated urinary tract infections
    • Cox CE, Graveline JF, Luongo JM. Review of clinical experience in the United States with Cefpodoxime proxetil in adults, with uncomplicated urinary tract infections. Drugs 1991; 42(suppl 1): 41-50.
    • (1991) Drugs , vol.42 , Issue.SUPPL. 1 , pp. 41-50
    • Cox, C.E.1    Graveline, J.F.2    Luongo, J.M.3
  • 15
    • 0025689363 scopus 로고
    • Cefpodoxime proxetil: Dosage, efficacy and tolerance in adults suffering from respiratory tract infections
    • Safran C. Cefpodoxime proxetil: dosage, efficacy and tolerance in adults suffering from respiratory tract infections. J Antimicrob Chemother 1990; 26(suppl E): 93-101.
    • (1990) J Antimicrob Chemother , vol.26 , Issue.SUPPL. E , pp. 93-101
    • Safran, C.1
  • 16
    • 0026319895 scopus 로고
    • Cefpodoxime proxetil in the treatment of skin and soft tissue infections
    • Tack KJ, Wilks NE, Semerdjian G, et al. Cefpodoxime proxetil in the treatment of skin and soft tissue infections. Drugs 1991; 42(suppl 3): 51-6.
    • (1991) Drugs , vol.42 , Issue.SUPPL. 3 , pp. 51-56
    • Tack, K.J.1    Wilks, N.E.2    Semerdjian, G.3
  • 17
    • 0025903674 scopus 로고
    • Treatment of uncomplicated urinary tract infection with ceftibuten
    • Stein GE, Christensen S, Mummaw N. Treatment of uncomplicated urinary tract infection with ceftibuten. Infection 1991; 19: 124-6.
    • (1991) Infection , vol.19 , pp. 124-126
    • Stein, G.E.1    Christensen, S.2    Mummaw, N.3
  • 18
    • 0027297861 scopus 로고
    • Comparison of the efficacy and safety of ceftibuten and cefaclor in the treatment of pneumonia and bronchiectasis
    • McCabe R, Rumans L, Perrotta R, Mogabgab W. Comparison of the efficacy and safety of ceftibuten and cefaclor in the treatment of pneumonia and bronchiectasis. J Chemother 1993; 5: 124-32.
    • (1993) J Chemother , vol.5 , pp. 124-132
    • McCabe, R.1    Rumans, L.2    Perrotta, R.3    Mogabgab, W.4
  • 19
    • 0343735687 scopus 로고
    • Worldwide safety experience with ceftibuten pediatric suspensions
    • Kammer RB. Worldwide safety experience with ceftibuten pediatric suspensions. Pediatr Infect Dis J 1993; 12: S92-4.
    • (1993) Pediatr Infect Dis J , vol.12
    • Kammer, R.B.1
  • 20
    • 2542544423 scopus 로고
    • Members of the ceftibuten otitis media United States study group. Multicenter controlled trial comparing ceftibuten with amoxicillin/clavulanate in the empiric treatment of acute otitis media
    • McLinn SE, Mccarty JM, Perrotta R, Pichiero ME, Reidenberg BE, Members of the Ceftibuten Otitis Media United States Study Group. Multicenter controlled trial comparing ceftibuten with amoxicillin/clavulanate in the empiric treatment of acute otitis media. Pediatr Infect Dis 1993; 12: S70-6.
    • (1993) Pediatr Infect Dis , vol.12
    • McLinn, S.E.1    Mccarty, J.M.2    Perrotta, R.3    Pichiero, M.E.4    Reidenberg, B.E.5
  • 21
    • 13744264628 scopus 로고
    • Loracarbef (LY 163892) in the treatment of acute exacerbations of chronic bronchitis. Results of US and European comparative clinical trials
    • Zeckel ML. Loracarbef (LY 163892) in the treatment of acute exacerbations of chronic bronchitis. Results of US and European comparative clinical trials. Am J Med 1992; 92(suppl 6A): 58S-64S.
    • (1992) Am J Med , vol.92 , Issue.SUPPL. 6A
    • Zeckel, M.L.1
  • 22
    • 0026658043 scopus 로고
    • Cefpodoxime proxetil compared with amoxicillin-clavulanate for the treatment of otitis media
    • Mendelman PM, Del Beccaro M, McLinn SE, Todd WM. Cefpodoxime proxetil compared with amoxicillin-clavulanate for the treatment of otitis media. J Pediatr 1992; 121: 460-5.
    • (1992) J Pediatr , vol.121 , pp. 460-465
    • Mendelman, P.M.1    Del Beccaro, M.2    McLinn, S.E.3    Todd, W.M.4
  • 23
    • 0025642564 scopus 로고
    • Efficacy and tolerance of cefpodoxime proxetil compared with co-amoxiclav in the treatment of exacerbations of chronic bronchitis
    • Periti P, Novelli A, Schildwachter G, Schmidt-Gayk H, Ryo Y, Zuck P. Efficacy and tolerance of cefpodoxime proxetil compared with co-amoxiclav in the treatment of exacerbations of chronic bronchitis. J Antimicrob Chemother 1990; 26(suppl E): 63-9.
    • (1990) J Antimicrob Chemother , vol.26 , Issue.SUPPL. E , pp. 63-69
    • Periti, P.1    Novelli, A.2    Schildwachter, G.3    Schmidt-Gayk, H.4    Ryo, Y.5    Zuck, P.6
  • 24
    • 0027189732 scopus 로고
    • Amoxycillin/clavulanic acid: A review of its efficacy in over 38500 patients from 1979 to 1992
    • Neu H, Wilson APR, Grüneberg RN. Amoxycillin/clavulanic acid: a review of its efficacy in over 38500 patients from 1979 to 1992. J Chemother 1993; 5: 67-93.
    • (1993) J Chemother , vol.5 , pp. 67-93
    • Neu, H.1    Wilson, A.P.R.2    Grüneberg, R.N.3
  • 25
    • 0001924647 scopus 로고
    • The effect of amoxicillin plus clavulanic acid on human bowel flora
    • Scheweningen
    • Mittermayer HW. The effect of amoxicillin plus clavulanic acid on human bowel flora. In: Proceedings of the European Symposium on Augmentin, Scheweningen, 1982; 125-33.
    • (1982) Proceedings of the European Symposium on Augmentin , pp. 125-133
    • Mittermayer, H.W.1
  • 26
    • 0021911428 scopus 로고
    • Clinical trials of BRL25000 (clavulanic acid-amoxicillin) on bacterial flora in human feces
    • Motohiro T, Tanaka K, Koga T, et al. Clinical trials of BRL25000 (clavulanic acid-amoxicillin) on bacterial flora in human feces. Jpn Antibiot 1985; 38: 507-37.
    • (1985) Jpn Antibiot , vol.38 , pp. 507-537
    • Motohiro, T.1    Tanaka, K.2    Koga, T.3
  • 27
    • 0021836620 scopus 로고
    • Effet de l'association amoxicilline-acide clavulanique sur la flore fecale aérobie de l'enfant
    • Borderon JC, Rastegar A, Rolland JC, Laugier J. Effet de l'association amoxicilline-acide clavulanique sur la flore fecale aérobie de l'enfant. Pathol Biol 1985; 33: 569-72.
    • (1985) Pathol Biol , vol.33 , pp. 569-572
    • Borderon, J.C.1    Rastegar, A.2    Rolland, J.C.3    Laugier, J.4
  • 28
    • 0022507090 scopus 로고
    • Effect of amoxicillin-clavulanate and cephradine in the fecal flora on healthy volunteers not exposed to a hospital environment
    • Brumfitt W, Franklin I, Grady D, Hamilton-Miller JMT. Effect of amoxicillin-clavulanate and cephradine in the fecal flora on healthy volunteers not exposed to a hospital environment. Antimicrob Agents Chemother 1986; 30: 335-7.
    • (1986) Antimicrob Agents Chemother , vol.30 , pp. 335-337
    • Brumfitt, W.1    Franklin, I.2    Grady, D.3    Hamilton-Miller, J.M.T.4
  • 29
    • 0018662787 scopus 로고
    • Effect of phenoxymethylpenicillin and clindamycm on the oral, throat and faecal microflora of man
    • Heimdahl A, Nord CE. Effect of phenoxymethylpenicillin and clindamycm on the oral, throat and faecal microflora of man. Scand J Infect Dis 1979; 11: 233-42.
    • (1979) Scand J Infect Dis , vol.11 , pp. 233-242
    • Heimdahl, A.1    Nord, C.E.2
  • 30
    • 0019521794 scopus 로고
    • Occurrence of toxin-producing clostridium difficile in antibiotic-associated diarrhea
    • Aronsson B, Mollby R, Nord CE. Occurrence of toxin-producing Clostridium difficile in antibiotic-associated diarrhea. Med Microbiol Immunol 1981; 170: 27-35.
    • (1981) Med Microbiol Immunol , vol.170 , pp. 27-35
    • Aronsson, B.1    Mollby, R.2    Nord, C.E.3
  • 31
    • 0017123744 scopus 로고
    • Formation of beta-lactamase in bacteroides fragilis: Cell-bound and extracellular activity
    • Olsson B, Nord CE, Wadström T. Formation of beta-lactamase in Bacteroides fragilis: cell-bound and extracellular activity. Antimicrob Agents Chemother 1976; 9: 727-35.
    • (1976) Antimicrob Agents Chemother , vol.9 , pp. 727-735
    • Olsson, B.1    Nord, C.E.2    Wadström, T.3
  • 32
    • 0030473876 scopus 로고    scopus 로고
    • Effects of omeprazole and amoxycillin on the human oral and gastrointestinal microflora in patients with helicobacter pylori infections
    • Stark C, Adamsson C, Edlund S. et al. Effects of omeprazole and amoxycillin on the human oral and gastrointestinal microflora in patients with Helicobacter pylori infections. J Antimicrob Chemother 1996; 38: 927-39.
    • (1996) J Antimicrob Chemother , vol.38 , pp. 927-939
    • Stark, C.1    Adamsson, C.2    Edlund, S.3
  • 37
    • 54949087584 scopus 로고
    • Multiple vergleiche verbundener stichproben nach wilcoxon and wilcox
    • Berlin, Heidelberg, New York: Springer-Verlag
    • Sachs L. Multiple Vergleiche verbundener Stichproben nach Wilcoxon and Wilcox. In: Angewandte Statistik. Anwendung statistischer Methoden, 8th edn. Berlin, Heidelberg, New York: Springer-Verlag, 1991: 673-5.
    • (1991) Angewandte Statistik. Anwendung Statistischer Methoden, 8th Edn. , pp. 673-675
    • Sachs, L.1
  • 38
    • 0028783445 scopus 로고
    • Review of the properties and features of ceftibuten: A new orally active antibiotic
    • Spector S. Review of the properties and features of ceftibuten: a new orally active antibiotic. Infect Dis Clin Pract 1995; 4: S113-23.
    • (1995) Infect Dis Clin Pract , vol.4
    • Spector, S.1
  • 41
    • 0028196567 scopus 로고
    • Ceftibuten pharmacokinetics and pharmacodynamics. Focus on paediatric use
    • Kearns GL, Young RA. Ceftibuten pharmacokinetics and pharmacodynamics. Focus on paediatric use. Clin Pharmacokinet 1994; 26: 169-89.
    • (1994) Clin Pharmacokinet , vol.26 , pp. 169-189
    • Kearns, G.L.1    Young, R.A.2
  • 42
    • 0027504576 scopus 로고
    • Cefpodoxime proxetil: A new, broad-spectrum, oral cephalosporin
    • Chocas EC, Paap CM, Godley PJ. Cefpodoxime proxetil: a new, broad-spectrum, oral cephalosporin. Ann Pharmacother 1993; 27: 1369-77.
    • (1993) Ann Pharmacother , vol.27 , pp. 1369-1377
    • Chocas, E.C.1    Paap, C.M.2    Godley, P.J.3
  • 43
    • 0026299902 scopus 로고
    • Pharmacokinetic and tolerance studies of cefpodoxime after single-and multiple-dose oral administration of cefpodoxime proxetil
    • Borin MT, Hughes GS, Patel RK, Royer ME, Cathcart KS. Pharmacokinetic and tolerance studies of cefpodoxime after single-and multiple-dose oral administration of cefpodoxime proxetil. J Clin Pharmacol 1991; 31: 1137-45.
    • (1991) J Clin Pharmacol , vol.31 , pp. 1137-1145
    • Borin, M.T.1    Hughes, G.S.2    Patel, R.K.3    Royer, M.E.4    Cathcart, K.S.5
  • 44
    • 0028239586 scopus 로고
    • Pharmacokinetics of cefpodoxime proxetil in healthy young and elderly volunteers
    • Borin MT, Ferry JJ, Forbes KK, Hughes GS. Pharmacokinetics of cefpodoxime proxetil in healthy young and elderly volunteers. J Clin Pharmacol 1994; 34: 774-81.
    • (1994) J Clin Pharmacol , vol.34 , pp. 774-781
    • Borin, M.T.1    Ferry, J.J.2    Forbes, K.K.3    Hughes, G.S.4
  • 45
    • 0027438205 scopus 로고
    • Pharmacokinetics and ex vivo susceptibility of cefpodoxime proxetil in patients receiving continuous ambulatory peritoneal dialysis
    • Johnson CA, Ateshkadi A, Zimmerman SW, et al. Pharmacokinetics and ex vivo susceptibility of cefpodoxime proxetil in patients receiving continuous ambulatory peritoneal dialysis. Antimicrob Agents Chemother 1993; 37: 2650-5.
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 2650-2655
    • Johnson, C.A.1    Ateshkadi, A.2    Zimmerman, S.W.3
  • 47
    • 0025649463 scopus 로고
    • Pharmacokinetics of cefpodoxime in young and elderly volunteers after singe doses
    • Tremblay D, Dupront A, Ho C, Cossediere D, Lenfant B. Pharmacokinetics of cefpodoxime in young and elderly volunteers after singe doses. J Antimicrob Chemother 1990; 26(suppl E): 21-8.
    • (1990) J Antimicrob Chemother , vol.26 , Issue.SUPPL. E , pp. 21-28
    • Tremblay, D.1    Dupront, A.2    Ho, C.3    Cossediere, D.4    Lenfant, B.5
  • 48
    • 0024836399 scopus 로고
    • The effects of gastric pH and food on the pharmacokinetics of a new oral cephalosporin, cefpodoxime proxetil
    • Hughes GS, Heald DL, Barker KL, et al. The effects of gastric pH and food on the pharmacokinetics of a new oral cephalosporin, cefpodoxime proxetil. Clin Pharmacol Ther 1989; 46: 674-85.
    • (1989) Clin Pharmacol Ther , vol.46 , pp. 674-685
    • Hughes, G.S.1    Heald, D.L.2    Barker, K.L.3
  • 49
    • 0344706720 scopus 로고
    • Comparative pharmacokinetics of cefotixam hexetil, cefuroxime, cefixime, cephalexin and effect of H2 blockers, standard breakfast and antacids on the bioavailability of cefuroxime hexetil
    • Washington, DC: American Society for Microbiology
    • Deppermann KM, Garbe C, Hasse K, Borner K, Koeppe P, Lode H. Comparative pharmacokinetics of cefotixam hexetil, cefuroxime, cefixime, cephalexin and effect of H2 blockers, standard breakfast and antacids on the bioavailability of cefuroxime hexetil [abstract]. In: 29th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, DC: American Society for Microbiology, 1989: 309.
    • (1989) 29th Interscience Conference on Antimicrobial Agents and Chemotherapy , pp. 309
    • Deppermann, K.M.1    Garbe, C.2    Hasse, K.3    Borner, K.4    Koeppe, P.5    Lode, H.6
  • 50
    • 0020383839 scopus 로고
    • Pharmacokinetics of amoxicillin and clavulanic acid administered alone and in combination
    • Adam D, De Visser I, Koeppe R. Pharmacokinetics of amoxicillin and clavulanic acid administered alone and in combination. Antimicrob Agents Chemother 1982; 22: 353-7.
    • (1982) Antimicrob Agents Chemother , vol.22 , pp. 353-357
    • Adam, D.1    De Visser, I.2    Koeppe, R.3
  • 51
    • 0003237982 scopus 로고
    • Augmentin: Absorption, excretion and pharmacokinetic studies in man
    • Jackson D, Cooper DL, Fier CW, Langley PP. Augmentin: absorption, excretion and pharmacokinetic studies in man. Postgrad Med 1984; 76(suppl): 51-70.
    • (1984) Postgrad Med , vol.76 , Issue.SUPPL. , pp. 51-70
    • Jackson, D.1    Cooper, D.L.2    Fier, C.W.3    Langley, P.P.4
  • 52
    • 0024986268 scopus 로고
    • Pharmacokinetics and tissue distribution of amoxicillin plus clavulanic acid after oral administration in man
    • Fraschini F, Scaglione F, Falchi M, et al. Pharmacokinetics and tissue distribution of amoxicillin plus clavulanic acid after oral administration in man. J Chemother 1990; 2: 171-7.
    • (1990) J Chemother , vol.2 , pp. 171-177
    • Fraschini, F.1    Scaglione, F.2    Falchi, M.3
  • 53
    • 0021668751 scopus 로고
    • The pharmacokinetics of orally absorbed cefuroxime compared with amoxicillin/clavulanic acid
    • Wise R, Bennett SA, Dent J. The pharmacokinetics of orally absorbed cefuroxime compared with amoxicillin/clavulanic acid. J Antimicrob Chemother 1984; 13: 603-10.
    • (1984) J Antimicrob Chemother , vol.13 , pp. 603-610
    • Wise, R.1    Bennett, S.A.2    Dent, J.3
  • 55
    • 0018143694 scopus 로고
    • CP-45,899, a beta-lactamase inhibitor that extends the antibacterial spectrum of beta-lactams: Initial bacteriological characterization
    • English AR, Retsema HA, Girard AE, Lynch JE, Barth WE. CP-45,899, a beta-lactamase inhibitor that extends the antibacterial spectrum of beta-lactams: initial bacteriological characterization. Antimicrob Agents Chemother 1978; 14: 414-19.
    • (1978) Antimicrob Agents Chemother , vol.14 , pp. 414-419
    • English, A.R.1    Retsema, H.A.2    Girard, A.E.3    Lynch, J.E.4    Barth, W.E.5
  • 57
    • 0023813571 scopus 로고
    • Amoxicillin/clavulanic acid levels in lower respiratory secretions
    • Gould IM, Reid TMS, Legge JS. Amoxicillin/clavulanic acid levels in lower respiratory secretions. J Antimicrob Chemother 1988; 22: 88-90.
    • (1988) J Antimicrob Chemother , vol.22 , pp. 88-90
    • Gould, I.M.1    Reid, T.M.S.2    Legge, J.S.3
  • 58
    • 0021042108 scopus 로고
    • Colonization pattern of the digestive tract by potentially pathogenic microorganisms and consequences for antibiotic treatment
    • van der Waaij D. Colonization pattern of the digestive tract by potentially pathogenic microorganisms and consequences for antibiotic treatment. Infection 1983; 11: 90-2.
    • (1983) Infection , vol.11 , pp. 90-92
    • Van Der Waaij, D.1
  • 59
    • 0025082643 scopus 로고
    • Impact of antimicrobial agents on human intestinal microflora
    • Nord CE, Edlund C. Impact of antimicrobial agents on human intestinal microflora. J Chemother 1990; 2: 218-37.
    • (1990) J Chemother , vol.2 , pp. 218-237
    • Nord, C.E.1    Edlund, C.2
  • 60
    • 0028067151 scopus 로고
    • The relationship between an increase in β-lactamase activity after oral administration of three new cephalosporins and protection against intestinal ecological disturbances
    • Edlund C. Stark C. Nord CE. The relationship between an increase in β-lactamase activity after oral administration of three new cephalosporins and protection against intestinal ecological disturbances. J Antimicrob Chemother 1994; 34: 127-38.
    • (1994) J Antimicrob Chemother , vol.34 , pp. 127-138
    • Edlund, C.1    Stark, C.2    Nord, C.E.3
  • 61
    • 0030802464 scopus 로고    scopus 로고
    • Influence of intravenously administered ciprofloxacin on aerobic intestinal microflora and fecal drug levels when administered simultaneously with sucralfate
    • Krueger WA, Ruckdeschel G, Unertl K. Influence of intravenously administered ciprofloxacin on aerobic intestinal microflora and fecal drug levels when administered simultaneously with sucralfate. Antimicrob Agents Chemother 1997; 41: 1725-30.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 1725-1730
    • Krueger, W.A.1    Ruckdeschel, G.2    Unertl, K.3
  • 62
    • 0027466589 scopus 로고
    • The in vitro inactivation of thirteen β-lactam antibiotics by other mechanisms than adsorption to faecal substance
    • De Vries-Hospers H, Jansen G, Tonk R, Oenema D, van der Waaij D. The in vitro inactivation of thirteen β-lactam antibiotics by other mechanisms than adsorption to faecal substance. Infection 1993; 21: 127-30.
    • (1993) Infection , vol.21 , pp. 127-130
    • De Vries-Hospers, H.1    Jansen, G.2    Tonk, R.3    Oenema, D.4    Van Der Waaij, D.5
  • 63
    • 0026354796 scopus 로고
    • A review of the pharmacokinetics of cefpodoxime proxetil
    • Borin MT. A review of the pharmacokinetics of cefpodoxime proxetil. Drugs 1991; 42(suppl 3): 13-21.
    • (1991) Drugs , vol.42 , Issue.SUPPL. 3 , pp. 13-21
    • Borin, M.T.1
  • 64
    • 0025344481 scopus 로고
    • Amoxicillin/clavulanic acid. An update of its antibacterial activity, pharmacokinetic properties and therapeutic use
    • Todd PH, Benfield P. Amoxicillin/clavulanic acid. An update of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs 1990; 39: 264-307.
    • (1990) Drugs , vol.39 , pp. 264-307
    • Todd, P.H.1    Benfield, P.2
  • 65
    • 0026757824 scopus 로고
    • Presence of clostridium difficile and antibiotic and beta-lactamase activities in feces of volunteers treated with oral cefixime, oral cefpodoxime proxetil, or placebo
    • Chachaty E, Depitre C, Mario N, et al. Presence of Clostridium difficile and antibiotic and beta-lactamase activities in feces of volunteers treated with oral cefixime, oral cefpodoxime proxetil, or placebo. Antimicrob Agents Chemother 1992; 36: 2009-13.
    • (1992) Antimicrob Agents Chemother , vol.36 , pp. 2009-2013
    • Chachaty, E.1    Depitre, C.2    Mario, N.3
  • 68
    • 0024339117 scopus 로고
    • A worldwide survey of clinical experience with augmentin
    • Croydon P. A worldwide survey of clinical experience with augmentin. J Drug Dev 1989; 2(suppl 1): 67-9.
    • (1989) J Drug Dev , vol.2 , Issue.SUPPL. 1 , pp. 67-69
    • Croydon, P.1
  • 69
    • 0027077783 scopus 로고
    • The efficacy and safety of once-daily ceftibuten compared with co-amoxiclav in the treatment of acute bacterial sinusitis
    • De Abate CA, Perrotta RJ, Dennington ML, Ziering RM. The efficacy and safety of once-daily ceftibuten compared with co-amoxiclav in the treatment of acute bacterial sinusitis. J Chemother 1992; 4: 358-63.
    • (1992) J Chemother , vol.4 , pp. 358-363
    • De Abate, C.A.1    Perrotta, R.J.2    Dennington, M.L.3    Ziering, R.M.4


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