Threshold dose response for tumor induction by genotoxic carcinogens modeled via cell-cycle delay

Toxicological Sciences

Volumn 49, Issue 1, 1999, Pages 110-115

  Lutz, Werner K ^a   Kopp Schneider, Annette ^b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Cancer risk assessment; Cell cycle delay; Chemical carcinogenesis; Dose response relationships; Threshold

Indexed keywords

CARCINOGEN;

ANIMAL CELL; ARTICLE; CANCER RISK; CARCINOGENESIS; CELL CYCLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CYTOTOXICITY; DNA REPLICATION; GENOTOXICITY; MUTATION; NONHUMAN; RAT; RISK ASSESSMENT;

ANIMALS; ANTICARCINOGENIC AGENTS; CARCINOGENICITY TESTS; CARCINOGENS; CELL CYCLE; CELL DIVISION; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENES, CDC; MODELS, BIOLOGICAL; MUTAGENS; TIME FACTORS;

EID: 0032992146     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/49.1.110     Document Type: Article

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