Myotonic dystrophy protein kinase expressed in rat cardiac muscle is associated with sarcoplasmic reticulum and gap junctions

Journal of Histochemistry and Cytochemistry

Volumn 47, Issue 3, 1999, Pages 383-392

  Mussini, Isabella ^a   Biral, Donatella ^a   Marin, Oriano ^a   Furlan, Sandra ^a   Salvatori, Sergio ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Cardiac muscle; Connexin 43; DMPK; Excitation contraction coupling; Gap junctions; Immunoelectron localization; Myotonic dystrophy protein kinase; Sarcoplasmic reticulum; Terminal cisternae

Indexed keywords

PROTEIN KINASE;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; CELLULAR DISTRIBUTION; CONFOCAL LASER MICROSCOPY; GAP JUNCTION; HEART MUSCLE; MALE; MYOTONIC DYSTROPHY; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SARCOPLASMIC RETICULUM; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; TRINUCLEOTIDE REPEAT;

ANIMALIA;

EID: 0032992140     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215549904700312     Document Type: Article

References (43)

1. Angst BD, Buxton RS, Magee AI (1993) Characterization of human cardiac desmosomal cadherins. Ann NY Acad Sci 752:101-104
2. Beardslee MA, Laing JG, Beyer FC, Saffitz JF. (1998) Rapid turnover of connexin43 in the adult rat heart. Circ Res 83:629-635
3. Brink PA, Ferreira A, Moolman JC, Weymar HW, Vandermerwe PL, Corfield VA (1995) Gene for progressive familial heart-block type-1 maps to chromosome 19q13. Circulation 91:1633-1640
4. Britz-Cunningham SH, Shah MM, Zuppan CW, Fletcher WH (1995) Mutations of the connexin43 gap-junction gene in patients with heart malformations and defects of laterality. N Engl J Med 332:1323-1329
5. Bruzzone R, White TW, Paul DL (1996) Connections with connexins: the molecular basis of direct intercellular signaling. Eur J Biochem 238:1-27
6. Buxton RS, Cowin P, Franke VTW, Garrod DR, Green KJ, King IA, Koch PJ, Magee AI, Rees DR, Stanley JR, Steinherg MS (1993) Nomenclature of the desmosomal cadherins. J Cell Biol 111: 581-588
7. Cartegni L, di Barletta MR, Barresi R, Squarzoni S, Sabatelli S, Maraldi N, Mora M, Di Blasi C, Cornelio F, Merlini L, Villa A, Cobianchi F, Toniolo D (1997) Heart-specific localization of emerin: new insights into Emery-Dreifuss muscular dystrophy. Hum Mol Genet 6:2257-2264
8. Cox GF, Kunkel LM (1997) Dystrophies and heart disease. Curr Opin Cardiol 12:329-343
9. Damiani K, Picello E, Saggin L, Margreth A (1995) Identification of triadin and of histidine-rich Ca2+-binding protein as substrates of 60 kDa calmodulin-dependent protein kinase in junctional terminal cisternae of sarcoplasmic reticulum of rabbit fast muscle. Biochem Biophys Res Commun 209:457-465
10. Dolber PC, Sommer JR (1984) Corbular sarcoplasmic reticulum of rabbit cardiac muscle. J Ultrastruct Res 87:190-196
11. Godwin AJ, Green LM, Walsh MP, McDonald JR, Walsh DA, Fletcher WH (1993) In situ regulation of cell-cell communication by the cAMP-dependent protein kinase and protein kinase C. Mol Cell Biochem 127-128:293-307
12. Goodenough DA, Goliger JA, Paul DL (1996) Connexins, connexons and intercellular communication. Annu Rev Biochem 65: 475-502
13. Jansen G, Groenen PJTA, Bachner D, Jap PHK, Coerwinkel M, Oerlemans F, van den Brock W, Gohlsch B, Perte D, Plomp JJ, Molenaar PC, Nederhoff MGJ, van Echteld CJA, Dekker M, Berns A, Hameister H, Wieringa B (1996) Abnormal myotonic dystrophy protein kinase levels produce only mild myopathy in mice. Nature Genet 13:316-324
14. Kemler R (1993) From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet 9:317-321
15. Kensler RW, Goodenough DA (1980) Isolation of mouse myocardial gap junctions. J Cell Biol 86:755-764
16. Kijma Y, Saito A, Jetton TL, Magnuson MA, Fleischer S (1993) Different intracellular localization of inositol 1,4,5-trisphosphate and ryanodine receptors in cardiomyocytes. J Biol Chem 268: 3499-3506
17. 4. Nature 227:680-685
18. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurements with the Folin phenol reagent. J Biol Chem 193:265-275
19. Meldrum DR, Cleveland JC, Rowland RT, Banerjee A, Harken AH (1996) Calcium-induced inotropy is in part mediated by protein kinase C. J Surg Res G3:400-405
20. Moreno AP, Saez JC, Fishman GI, Spray DC (1994) Human connexin 43 gap junction channels. Regulation of unitary conductances by phosphorylation. Circ Res 74:1050-1057
21. Musil LS, Goodenough DA (1991) Biochemical analysis of connexin 43 intracellular transport, phosphorylation and assembly into gap junctional plaques. J Cell Biol 115:1357-1374
22. Mussini I, Biral D, Marin O, Salvatori S (1996) Subcellular distribution of myotonic dystrophy protein kinase in cardiac muscle fibers. Third Internet World Congress, PDI0409
23. Ogata T, Yamasaki Y (1990) High-resolution scanning electron microscopic studies on the three-dimensional structure of the trans-verse-axial tubular system, sarcoplasmic reticulum and intercalated disc of the rat myocardium. Anat Rec 228:277-287
24. Phillips MF, Harper PS (1997) Cardiac disease in myotonic dystrophy. Cardiovasc Res 33:13-22
25. Reaume AG, de Sousa PA, Kulkarni S, Langille BL, Zhu D, Davies TC, Juneja SC, Kidder GM, Rossant J (1995) Cardiac malformation in neonatal mice lacking connexin 43. Science 267:1831-1834.
26. Reddy S, Smith DB, Rich MM, Leferovich JM, Reilly P, Davis BM, Tran K, Rayburn H, Bronson R, Cros D, Balice-Gordon RJ, Housman D (1996) Mice lacking the myotonic dystrophy protein kinase develop a late onset progressive myopathy. Nature Genet 13:325-335
27. Saez JC, Nairn AC, Czernick A, Spray DC, Hertzberg HL, Greengard P, Bennett MVL. (1990) Phosphorylation of connexin 32, the hepatocyre gap junction protein, by cAMP dependent protein kinase, protein kinase C and Ca2+/calmodulin-dependent protein kinase II. Eur J Biochem 192:263-273
28. Saez JC, Spray DC, Nairn AC, Hertzberg EL, Greengard P, Bennett MVL (1986) cAMP increases junctional conductance and stimulates phosphorylation of the 27-kDa principal gap junction polypeptide. Proc Natl Acad Sci USA 83:2473-2477
29. Salvatori S, Biral D, Furlan S, Marin O (1994) Identification and localization of the myotonic dystrophy gene product in skeletal and cardiac muscles. Biochem Biophys Res Commun 203:1365-1370
30. Salvatori S, Biral D, Furlan S, Marin O (1997) Evidence for localization of the myotonic dystrophy protein kinase to the terminal cisternae of the sarcoplasmic reticulum. J Musc Res Cell Motil 18:1-12
31. Salviati G, Sorenson MM, Eastwood AB (1982) Calcium accumulation by the sarcoplasmic reticulum in two populations of chemically skinned human muscle fibers. J Gen Physiol 79:603-632
32. Severs NJ (1994) Pathophysiology of gap junctions in heart disease. J Cardiovasc Electrophysiol 5:462-475
33. Severs NJ (1995) Cardiac muscle cell interaction: from microanatomy to the molecular make-up of the gap junction. Histol Histopathol 10:481-501
34. Shimokawa M, Ishiura S., Kameda N, Yamamoto M, Sasagawa N, Saitoh N, Sorimachi H, Ueda H, Ohno S, Suzuki K, Kobayashi T (1997) A novel isoform of myotonin protein kinase: gene product of myotonic dystrophy is localized in the sarcoplasmic reticulum of skeletal muscle. Am J Pathol 150:1285-1295
35. Sommer JR, Jennings RB (1986) Ultrastructure of cardiac muscle. In Fozzard HA, Haber E, Jennings RB, Katz AM, Morgan HE, eds. The Heart and Cardiovascular System. New York, Raven Press, 61-100
36. Spach MS, Heidlage JF (1995) The stochastic nature of cardiac-propagation at a microscopic level. Electrical description of myocardial architecture and its application to conduction. Circ Res 76:366-380
37. Spray DC (1998) Gap junction proteins. Where they live and how they die. Circ Res 83:679-681
38. Stagg RB, Fletcher WH (1990) The hormone-induced regulation of contact-dependent cell-cell communication by phosphorylation. Endocrin Rev 11:302-325
39. Thomson AMP (1968) Dystrophia cordis myotonica studied by serial histology of the pacemaker and conducting system. J Pathol Bacteriol 96:285-295
40. Towbin H, Staehelin T, Gordon J (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets, procedure and some applications. Proc Natl Acad Sci USA 76:4350-4354
41. Ueda H, Kameda N, Baba T, Terada N, Shimokawa M, Yamamoto M, Ishiura S, Kobayashi T, Ohno S (1998) Immunolocalization of myotonic dystrophy protein kinase in corbular and junctional sarcoplasmic reticulum of human cardiac muscle. Histochem J 30:245-251
42. van der Ven PFM, Jansen G, Van Kuppevelt THMSM, Perryman MB, Lupa M, Dunne PW, Ter Laak HJ, Jap PHK, Veerkamp JH, Epstein HF, Wieringa B (1993) Myotonic dystrophy kinase is a component of neuromuscular junctions. Hum Mol Genet 2:1889-1894
43. Whiting EJ, Waring JD, Tamai K, Somerville MJ, Hincke M, Staines WA, Ikeda J, Korneluk R (1995) Characterization of myotonic dystrophy kinase (DMK) protein in human and rodent muscle and central nervous tissue. Hum Mol Genet 4:1063-1072