Hormone coexpression in the adult toad endocrine pancreas: Double-label immunofluorescence under basal conditions and after glucose injection

General and Comparative Endocrinology

Volumn 115, Issue 1, 1999, Pages 29-36

  Luna, Georgina ^a   Francini, Flavio ^a   Gómez Dumm, César L A ^a   Madsen, Ole ^b   Gagliardino, Juan J ^a  

^a University of La Plata CONICET   (Argentina)

^b HAGEDORN RESEARCH INSTITUTE   (Denmark)

Author keywords

Bufo arenarum; Glucagon; Glucose; Hormonal coexpression; Immunofluorescence; Insulin; Pancreas; Pancreatic polypeptide; Somatostatin

Indexed keywords

FLUORESCEIN; GLUCAGON; GLUCOSE; IMMUNOGLOBULIN G; INSULIN; PANCREAS HORMONE; PANCREAS POLYPEPTIDE; RHODAMINE; SOMATOSTATIN;

ANIMAL TISSUE; ARTICLE; CELL LEVEL; CELL TYPE; CONTROLLED STUDY; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HORMONE DETERMINATION; HORMONE RELEASE; HYPERGLYCEMIA; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE TEST; MALE; NONHUMAN; PANCREAS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REGULATORY MECHANISM; TOAD;

BUFO ARENARUM;

EID: 0032991757     PISSN: 00166480     EISSN: 10956840     Source Type: Journal    
DOI: 10.1006/gcen.1999.7294     Document Type: Article

References (31)

1. Alpert S., Hanahan D., Teitelman G. Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons. Cell. 53:1988;295-308.
2. Bordi C., Bussolati G. Immunofluorescence, histochemical and ultrastructural studies for the detection of multiple endocrine polypeptide tumours of the pancreas. Virchow Arch. B. 17:1974;13-27.
3. Bonner-Weir S., Weir G. C. The organization of the endocrine pancreas: A hypothetical unifying view of the phylogenetic differences. Gen. Comp. Endocrinol. 38:1979;28-37.
4. Cheung R., Andrews P. C., Plisetskaya E. M., Youson J. H. Immunoreactivity to peptides belonging to the pancreatic polypeptide family (NPY, aPY, PP, PYY) and to glucagon like peptide in the endocrine pancreas and anterior intestine of adult lampreys, Petromyzon marinus: An immunocytochemical study. Gen. Comp. Endocrinol. 81:1991;51-63.
5. De Krijger R. R., Aanstoot H. J., Kranenburg G., Reinhard M., Visser W. J., Bruining G. J. The midgestational human fetal pancreas contains cell coexpressing islet hormones. Dev. Biol. 153:1992;368-375.
6. Della Rossa A., Putti R. The endocrine pancreas of lacertids: An immunocytochemical study of the genera Pedioplanis and Meroles. Eur. J. Histochem. 39:1995;47-58.
7. El-Salhy M., Wilander E., abu-Sinna G. The endocrine pancreas of anuran amphibians: A histological and immunocytochemical study. Biomed. Res. 3:1982;579-589.
8. Francini F., Gagliardino J. J. An in vitro model suitable for studying insulin secretion in amphibians. Gen. Comp. Endocrinol. 98:1995;121-128.
9. Francini F., Madsen O., Gómez Dumm C. L. A., Gagliardino J. J. Topographic differences in cell populations and insulin secretion in the endocrine pancreas of the toad Bufo arenarum. Gen. Comp. Endocrinol. 104:1996;346-355.
10. Hashimoto T., Kawano H., Daikoku S., Shima K., Taniguchi H., Baba S. Transient coappearance of glucagon and insulin in the progenitor cell of the rat pancreatic islets. Anat. Embryol. 178:1988;489-497.
11. Jönsson A. C. Co-localization of peptides in the Brockmann bodies of the cod (Gadus morhua) and the rainbow trout (Oncorhyncus mykiss). Cell Tissue Res. 273:1993;547-555.
12. Kaung H-L., Elde R. P. Distribution and morphometric quantitation of pancreatic endocrine cell types in the frog, Rana pipiens. Anat. Rec. 196:1980;173-181.
13. Lange R. H., Ali S. S., Klein C., Trandaburu T. Immunohistochemical demonstration of insulin and glucagon in islet tissue of reptiles, amphibians and the teleosts using epoxy-embedded material and antiporcine hormone sera. Acta Histochem. 52:1975;71-78.
14. Larsson L-I., Grimelius L., Håkanson R., Rehfeld J. F., Stadil F., Holst J., Angervall L., Sundler F. Mixed endocrine pancreatic tumors producing several peptide hormones. Am. J. Pathol. 79:1975;271-284.
15. Lukinius A., Ericsson J. L. E., Grimelius L., Korsgren O. Ultrastructural studies of the ontogeny of fetal human and porcine endocrine pancreas, with special reference to colocalization of the four major islet hormones. Dev. Biol. 153:1992;376-390.
16. Maake C., Hanke W., Reinecke M. An immunohistochemical and morphometric analysis of insulin, insulin-like growth factor I, glucagon, somatostatin, and PP in the development of the gastro-entero-pancreatic system of Xenopus laevis. Gen. Comp. Endocrinol. 110:1998;182-195.
17. Madsen O. D., Karlsen C., Serup P., Lund K., Nielsen E., Petersen H. V., Blume N., Petersen J. S., Karlsen A. E., Michelsen B. K., Holst J. J., Larsson L-I. Studies of pluripotent islet tumour cell differentiation in relation to diabetes. Flatt P., Lenzen S. Frontiers of Insulin Secretion and Pancreatic B-Cell Research. 1994;61-68 Smith-Gordon and Company Limited, London.
18. Madsen O. D., Larsson L-I., Rehfeld J. F., Schwartz T., Lernmark Å., Labrecque A., Steiner D. F. Cloned cell lines from a transplantable insulinoma are heterogeneous and express cholecystokinin in addition to islet hormones. J. Cell Biol. 103:1986;2025-2034.
19. Pérez-Tomas R., Ballesta J., Pastor L. M., Madrid J. F., Polak J. M. Comparative immunohistochemical study of the gastroenteropancreatic endocrine system of three reptiles. Gen. Comp. Endocrinol. 76:1989;171-181.
20. Pipeleers D. G., Schuit F. C., in't Veld P. A., Maes E., Hooghe-Peters E. L., Van de Winkel M., Gepts W. Interplay of Nutrients and Hormones in the Regulation of Insulin Release. Endocrinology. 117:1985;824-833.
21. Putti R., Della Rossa A. Peptide YY and insulin coexist in β-granules in B cells of the Madagascan lizard, Zonosaurus laricaudalus. Gen. Comp. Endocrinol. 103:1996;249-256.
22. Putti R., Varano L., Laforgia V., Cavagnuolo A. The endocrine pancreas of Triturus cristatus: An immunocytochemical study. Basic Appl. Histochem. 34:1990;219-228.
23. Putti R., Maglio M., Della Rossa A., Laforgia V., Varano L. An immunocytochemical study of the endocrine pancreas in three genera of lacertids from the Mediterranean basin. Valakos E. D., Bôhme W., Pérez-Mellado V., Maragou P. Lacertids of the Mediterranean Region. 1993;107-119 Alicante, Athens/Bonn.
24. Putti R., Della Rossa A., Tagliafierro G., Maglio M. Cell composition and costored peptides in the endocrine pancreas of Rana arvalis. Eur. J. Histochem. 39:1995;59-68.
25. Reddy S., Bibby N. J., Elliott R. B. An immunocytochemical study of endocrine cell development in the early fetal guinea pig pancreas. Gen. Comp. Endocrinol. 86:1992;275-283.
26. Rothen W. B. Co-localization of glucagon and pancreatic polypeptide in testudine pancreas. Experientia. 43:1987;428-430.
27. Schuit F. C., Pipeleers D. G. Regulation of adenosine 3′,5′-monophosphate levels in the pancreatic B cell. Endocrinology. 117:1985;834-840.
28. Teitelman G., Alpert S., Polak J. M., Martinez A., Hanahan D. Precursor cells of mouse endocrine pancreas coexpress insulin, glucagon and the neuronal proteins tyrosine hydroxylase and neuropeptide Y, but not pancreatic polypeptide. Development. 118:1993;1031-1039.
29. Tomita T., Pollock H. G. Four pancreatic endocrine cells in the bullfrog (Rana catesbeiana). Gen. Comp. Endocrinol. 45:1981;355-363.
30. von Lawzewitsch I. Anatomía y citología del páncreas y del islote de Langerhans en el sapo Bufo arenarum Hensel. An. Anat. 19:1970;523-532.
31. von Lawzewitsch I. Modificaciones del islote de Langerhans y renales del sapo por exceso de glucosa. Rev. Soc. argent. Biol. 38:1962;320-330.