Pneumocystis carinii pneumonia in HIV-infected patients: Effect of steroid therapy on surfactant level

Respiratory Medicine

Volumn 93, Issue 6, 1999, Pages 373-378

  Dichter, J R ^a   Lundgren, J D ^b   Nielsen, T L ^b   Jensen, B N ^b   Schattenkerk, J ^c   Benfield, T L ^b   Lawrence, M ^a   Shelhamer, J ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DIPALMITOYLPHOSPHATIDYLCHOLINE; LUNG SURFACTANT; METHYLPREDNISOLONE; PHOSPHOLIPID; STEROID;

ADJUVANT THERAPY; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; GAS CHROMATOGRAPHY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LUNG LAVAGE; MALE; PNEUMOCYSTIS PNEUMONIA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STEROID THERAPY;

EID: 0032991488     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1053/rmed.1999.0581     Document Type: Article

References (29)

1. Ballard P. Hormonal regulation of pulmonary surfactant. Endocr Rev 1989; 10: 165-181.
2. Escamilla R, Prevost M-C, Hermant C, Daratero AA, Cariven C, Krempf M. Surfactant analysis during Pneumocystis carinii pneumonia in HIV-infected patients. Chest 1992; 101: 1558-1562.
3. Hoffman A, Lawerence M, Ognibene F, et al. Reduction of pulmonary surfactant in patients with human immunodeficiency virus infection and Pneumocystis carinii pneumonia. Chest 1992; 102: 1730-1736.
4. Phelps D, Rose R. Increased recovery of surfactant protein A in AIDS-related pneumonia. Am Rev Respir Dis 1991; 143: 1072-1075.
5. Rose R, Catalano P, Koziel H, Furlong S. Abnormal lipid composition of bronchoalveolar lavage fluid obtained from individuals with AIDS-related lung disease. Am J Respir Crit Care Med 1994; 149: 332-338.
6. Sheehan P, Strokes D, Yeh Y, Hughes W. Surfactant and lavage phospholipase A2 in experimental Pneumocystis carinii pneumonia. Am Rev Respir Dis 1986; 134: 526-531.
7. Rice W, Singleton F, Linke M, Walzer P. Regulation of surfactant phosphatidylcholine secretion from alveolar Type II cells during Pneumocystis carinii pneumonia in the rat. J Clin Invest 1993; 92: 2778-2782.
8. Nielsen T, Schattenkerk J, Jensen B, et al. Adjunctive corticosteroid therapy for Pneumocystis carinii pneumonia in AIDS: a randomized European multicenter open label study. J Acquir Immune Defic Syndr 1992; 5 : 726-731.
9. Gagnon S, Boota A, Fischl M, Baier H, Kirksey O, La Voie L. Corticosteroids as adjunctive therapy for severe Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. N Eng! J Med 1990; 323: 1444-1450.
10. Bozette SA, Sattler SR, Chiu J, et al. A controlled trial of early adjunctive treatment with corticosteroids for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. N Engl J Med 1990; 323: 1451-1457.
11. Montaner J, Lawson L, Levitt N, Belzberg A, Schechter M, Ruedy J. Corticosteroids prevent early deterioration in patients with moderately severe Pneumocystis carinii pneumonia and the acquired immunodeficiency syndrome (AIDS). Ann Intern Med 1990; 113: 14-20.
12. The National Institutes of Health-University of California Expert Panel for corticosteroids as adjunctive therapy for Pneumocystis pneumonia. Consensus statement on the use of corticosteroids as adjunctive therapy for Pneumocystis pneumonia in the acquired immunodeficiency syndrome. N Engl J Med 1990; 323: 1500-1504.
13. Folch I, Lees M, Sloane-Stanley G. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 1957; 226: 497-509.
14. Rouser G, Fleischer S, Yamamoto A. Two dimensional thin layer chromatographic separation of polar lipids and determination of phospholipids by phosphorous analysis of spots. Lipids 1970; 5: 494-496.
15. Arvidson G. Structural and metabolic heterogeneity of rat liver glycerophosphatides. Eur J Biochem 1968; 4: 478-486.
16. Kuksis A, Myher I, Marai L, Geher K. Determination of plasma lipid profiles by automated gas chromatography and computerized data analysis. J Chromatogr Science 1975; 13: 423-430.
17. Huang L, Hecht F, Stansell I, Montanti R, Hadley W, Hopewell P. Suspected Pneumocystis carinii pneumonia with a negative induced sputum examination. Am J Respir Crit Care Med 1995; 151: 1866-1871.
18. Wallace J, Rao A, Glassroth J, et al. Respiratory illnes in persons with human immunodeficiency virus infection. Am Rev Respir Dis 1993; 148: 1523-1529.
19. Martin W. Pathogenesis of Pneumocystis carinii pneumonia. Am J Respir Cell Mol Biol 1993; 8: 356-357.
20. Gregory T, Longmore W, Moxley M, et al. Surfactant chemical composition and biophysical activity in acute respiratory distress syndrome. J Clin Invest 1991; 88: 1976-1981.
21. Pison U, Seeger W, Buchhorn R, et al. Surfactant abnormalities in patients with respiratory failure after multiple trauma. Am Rev Respir Dis 1989; 140: 1033-1039.
22. Baughman R, Sternberg R, Hull W, Buchsbaum J, Whitsett J. Decreased surfactant protein A in patients with bacterial pneumonia. Am Rev Respir Dis 1993; 147: 653-657.
23. LeVine A, Lotze A, Stanley S, et al. Surfactant content in children with inflammatory lung disease. Crit Care Med 1996; 24: 1062-1067.
24. Wispe J, Clark J, Warner B, et al. Tumor necrosis factor alpha inhibits expression of pulmonary surfactant protein. J Clin Invest 1990; 86: 1954-1960.
25. Balibrea-Cantero J, Arias-Diaz J, Garcia C, et al. Effect of pentoxifylline on the inhibition of surfactant synthesis induced by TNA-a in human type II pneumocytes. Am J Respir Crit Care Med 1994; 149: 699-706.
26. Liau D, Barrett C, Bell A, Ryan S. Functional abnormalities of lung surfactant in experimental acute alveolar injury in the dog. Am Rev Respir Dis 1987; 136: 395-401.
27. Lewis J, Ikegama M, Jobe A. Altered surfactant function and metabolism in rabbits with acute lung injury. J Appl Physiol 1990; 69: 2302-2310.
28. Bentsen K, Nielsen T, Shattenkerk J, Jensen B, Lundgren J. Serum Type III procollagen peptide in patients with Pneumocystis carinii infection. Am Rev Respir Dis 1993; 148: 1558-1562.
29. Benfield T, Schattenkerk J, Hofmann B, Jensen B, Nielsen T, Lundgren J. Differential effect on serum neopterin and serum b2-microglobulin is induced by treatment in Pneumocystis carinii pneumonia. J Infect Dis 1994; 169: 1170-1173.