DNA image cytometry in MDS bone marrow smears

British Journal of Haematology

Volumn 105, Issue 4, 1999, Pages 960-965

  Widell, Susanne ^a   Hast, Robert ^b   Auer, Gert ^a   Cox, Christopher ^c   Bennett, John M ^c  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b Division Haematology   (Sweden)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Cytogenetics; DNA cytometry; Intramarrow cell death; Leukaemia; MDS

Indexed keywords

CELL NUCLEUS DNA;

ADULT; AGED; ANEUPLOIDY; ARTICLE; BONE MARROW BIOPSY; CELL DEATH; CELL NUCLEUS; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DNA CONTENT; FEMALE; HUMAN; HUMAN CELL; MALE; MYELODYSPLASTIC SYNDROME; PLOIDY; PRIORITY JOURNAL; SCHOOL CHILD;

ADULT; AGED; APOPTOSIS; BONE MARROW CELLS; DNA; FEMALE; HUMANS; IMAGE CYTOMETRY; MALE; MIDDLE AGED; MYELODYSPLASTIC SYNDROMES; SENSITIVITY AND SPECIFICITY;

EID: 0032991422     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1999.01466.x     Document Type: Article

References (30)

1. Alanen, K.A., Joensuu, H. & Klemi, P.J. (1991) DNA content analysis of fine needle aspirates obtained from lymphatic tissue. Analytical and Quantitative Cytology and Histology, 15, 259-264.
2. Auer, G., Askensten, U. & Ahrens, O. (1989) Cytophotometry. Human Pathology, 20, 518-527.
3. Auffermann, W., Fohlmeister, I. & Böcking, A. (1988) Diagnostic and prognostic value of DNA image cytometry in myelodysplasia. Journal of Clinical Pathology, 41, 604-608.
4. Bacus, J.W. & Grace, L.J. (1987) Optical microscope system for standarized cell measurements and analyses. Applied Optics, 26, 3280-3293.
5. Barlogie, B., Stass, S., Dixon, D., Keating, M., Cork, A., Trujillo, J.M., McCredie, K.B. & Freireich, E.J. (1987) DNA aneuploidy in adult acute leukemia. Cancer Genetics and Cytogenetics, 28, 213-228.
6. Bauer, T.W., Tubbs, R.R., Edinger, M.G., Suit, P.F., Gephardt, G.N. & Levin, H.S. (1990) A prospective comparison of DNA quantitation by image and flow cytometry. American Journal of Clinical Pathology, 93, 322-326.
7. Bennett, J.M., Catovsky, D., Daniel, M.T., Flandrin, G., Galton, D.A.G., Gralnick, H.R. & Sultan, C., The French-American-British (FAB) Co-operative Group (1982) Proposals for the classification of the myelodysplastic syndromes. British Journal of Haematology, 51, 189-199.
8. Clark, R., Peters, S., Hoy, T., Smith, S., Whittaker, K. & Jacobs, A. (1986) Prognostic importance of hypodiploid hemopoietic precursors in myelodysplastic syndromes. New England Journal of Medicine, 314, 1472-1475.
9. Czader, M. (1996) Ploidy, cell proliferation and apoptosis in lymphoid malignancies. Thesis. Karolinska Institute, Stockholm, Sweden.
10. Czader, M., Porwit, A., Söderhäll, S., Blennow, E., Widell, S., Reizenstein, P., Öst, A. & Auer, G. (1993) DNA image analysis in childhood acute lymphoblastic leukemia. Leukemia and Lymphoma, 9, 229-235.
11. Goasguen, J-E. & Bennett, J-M. (1992) Classification and morphologic features of the myclodysplastic syndromes. Seminars in Oncology, 19, 4-13.
12. Goasguen, J-E., Bennett, J.M., Cox, C., Hambley, H., Mufti, G. & Flandrin, G. (1991) Prognostic implication and characterization of the blast cell population in the myelodysplastic syndrome. Leukemia Research, 15, 1159-1165.
13. Greenberg, P., Cox, C., LeBeau, M.M., Fenaux, P., Morel, P., Sanz, G., Sanz, M., Vallespi, T., Hamblin, T., Oscier, D., Ohyashiki, K., Toyama, K., Aul, C., Mufti, G. & Bennett, J.M. (1997) International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood, 89, 2079-2088.
14. Hiddemann, W., Schumann, J., Andreef, M., Barlogie, B., Herman, C.J., Leif, R.C., Mayall, B.H., Murphy, R.F. & Sandberg, A.A. (1984) Convention on nomenclature for DNA cytometry, Cancer Genetics and Cytogenetics, 13, 181-183.
15. Hiddemann, W., Wörmann, B., Göhde, W. & Büchner, T. (1986) DNA aneuploidies in adult patients with acute myeloid leukemia: incidence and relation to patient characteristics and morphologic subtypes. Cancer, 57, 2146-2152.
16. Hoy, T.G., Geddes, A.D. & Jacobs, A. (1989) DNA index and karyotype analysis in myelodysplasia. Journal of Clinical Pathology, 42, 498-501.
17. Kamihira, S., Atogami, S., Sohda, H., Momita, S., Toryia, K., Ikeda, S., Yamada, Y. & Tomonaga, M. (1994) DNA aneuploidy of adult T-cell leukemia cells. Leukemia Research, 18, 79-84.
18. Kroef, M.J.P.L., Bolk, M.J.W., Muus, P., Wessels, J.W. Beverstock, G.C., Willemze, R. & Landegent, J.E. (1997) Mosaicism of the 5q deletion as assessed by interphase FISH is a common phenomenon in MDS and restricted to myeloid cells. Leukemia, 11, 519-525.
19. Kropff, M., Chatclain, R., Muller, C.P., Wagner, A., Wenzel, T., Böhmer, H. & Böcking, A. (1991) Monitoring DNA cytometric parameters during the course of chronic myelogenous leukemia. Analytical and Quantitative Cytology and Histology, 13, 433-439.
20. Look, T.A., Roberson, P., Williams, D.L., Rivera, G., Rowman, W.P., Pui, C.H., Ochs, J., Abromowitch, M., Kalwinsky, D., Dahl, G.V., George, S. & Murphy, S.B. (1985) Prognostic importance of blast cell DNA content in childhood acute lymphoblastic leukemia. Blood, 65, 1079-1086.
21. Montecucco, C., Riccardi, A., Traversi, E., Danova, M., Ucci, G., Manzzini, G. & Giordano, P. (1983) Flow cytometric DNA content in myelodysplastic syndromes. Cytometry, 4, 238-243.
22. Muller, C.P., Kropff, M., Biesterfeld, S., Chatelain, R., Wagner, A., Wohltmann, D. & Böcking, A. (1991) Detection of high risk patients in chronic myelogenous leukemia by DNA image cytometry. Anticancer Research, 11, 617-624.
23. Parikh, P.M., Ashokkumar, M.S., Pai, S.K., Redkar, A., Chopra, H.K., Barbahya, S.A., Gopal, R., Mittra, I. & Advani, S.H. (1995) Prognostic significance of DNA index by flow cytometry in acute lymphoblastic leukemia. Indian Journal of Medical Research, 102, 24-27.
24. Peters, S.W., Clark, R.E., Hoy, T.G. & Jacobs, A. (1986) DNA content and cell cycle analysis of bone marrow cells in myelodysplastic syndromes (MDS). British Journal of Haematology, 62, 239-245.
25. Suciu, S., Kuse, R., Weh, H.J. & Hossfeld, D.K. (1990) Results of chromosome studies and their relation to morphology, course, and prognosis in 120 patients with de novo myelodysplastic syndrome. Cancer Genetics and Cytogenetics, 44, 15-26.
26. Vidriales, M.B., Orfao, A., Lopez-Berges, M.C., Gongales, M., Lopez-Macedo, A., Ciudad, J., Lopez, A., Canizo, M.C., Garcia, M.A. & San Miguel, J.F. (1995) DNA aneuploidy in acute myeloblastic leukemia is associated with a high expression of lymphoid markers. Cytometry (Communications in Clinical Cytometry), 22, 22-25.
27. Widell, S., Auer, G., Hast, R. & Reizenstein, P. (1993a) Comparison of acute myeloid leukemia occurring de novo or preceded by a myelodysplastic stage: differences in cellular DNA content. American Journal of Hematology, 42, 293-298.
28. Widell, S., Auer, C., Hast, R. & Reizenstein, P. (1991b) Variation in DNA content of immature normal bone marrow cells. American Journal of Hematology, 43, 291-294.
29. Widell, S., Czader, M., Porwit, A., Reizenstein, P., Hast, R. & Auer, G. (1993c) Methodological aspects of DNA image cytometry in normal bone marrow smears. Analytical Cellular Pathology, 5, 367-376.
30. Widell, S. (1994) Morphological and DNA cytometrical studies in myelodysplastic syndromes and acute myeloid leukemia. Thesis, Karolinska Institute, Stockholm, Sweden.