Interaction of the tyrosine phosphatase inhibitor ortho-vanadate on stimulus-secretion coupling in pancreatic acinar cells

Scandinavian Journal of Gastroenterology

Volumn 34, Issue 2, 1999, Pages 208-214

  Siegel, Erhard G ^a   Meyer Alber, A ^a   Seebeck, J ^a   Folsch U R ^a   Schmidt, W E ^a  

^a UNIVERSITY OF KIEL   (Germany)

Author keywords

Cholecystokinin 8; Ortho vanadate; Pancreatic acini; Tyrosine phosphatase inhibitor; Vanadate

Indexed keywords

AMYLASE; ORTHOVANADIC ACID; PHOSPHATASE; PROTEIN TYROSINE KINASE; THAPSIGARGIN; VANADIC ACID;

ACINAR CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; DEPHOSPHORYLATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; MALE; NONHUMAN; PANCREAS CELL; PRIORITY JOURNAL; RAT; SECRETION; SIGNAL TRANSDUCTION;

EID: 0032989358     PISSN: 00365521     EISSN: None     Source Type: Journal    
DOI: 10.1080/00365529950173113     Document Type: Article

References (30)

1. Williams JA, Yule DI. Stimulus-secretion coupling in pancreatic acinar cells. In: Go VLW, Dimagno EP, Gardner JD, Lebendial E, Reber HA, Scheele GA, editors. The pancreas - biology, pathobiology and disease. 2nd ed. New York: Raven Press; 1993. p. 167-91.
2. Cohen P. The role of protein phosphorylation in neural and hormonal control of cellular activity. Nature 1982;296:613-20.
3. Wagner ACC, Wishart MJ, Yule DI, Williams JA. Effects of okadaic acid indicate a role for dephosphorylation in pancreatic stimulus-secretion coupling. Am J Physiol 1992; 263:C1172-80.
4. Wagner ACC, Schäfer C, Williams JA. Effects of calyculin A on amylase release in streptolysin-O permeabilized acinar cells. Biochem Biophys Res Commun 1993;189:1606-12.
5. Schmidt WE, Meyer-Alber A, Waschulewski IH, Fetz I, Höcker M, Kern HF, et al. Serine/threonine phosphatases play a role in stimulus-secretion coupling in pancreatic acinar cells. Z Gastroenterol 1994;32:226-35.
6. Meyer-Alber A, Höcker M, Fetz I, Fornefeld H, Waschulewski IH, Fölsch UR, et al. Differential inhibitory effects of serine/ threonine phosphatase inhibitors and a calmodulin antagonist on phosphoinositol/calcium- and cAMP-mediated pancreatic amylase secretion. Scand J Gastroenterol 1995;30:384-91.
7. Meyer-Alber A, Fetz I, Waschulewski IU, Höcker M, Fölsch UR, Schmidt WB. Calyculin A, okadaic acid and W-7 interfere with a distal step in pancreatic acinar signal transduction. Biochem Biophys Res Commun 1994;201:1470-6.
8. Lutz MP, Sutor SL, Abraham RT, Miller LJ. A role for cholecystokinin-stimulated protein tyrosine phosphorylation in regulated secretion by the pancreatic acinar cell. J Biol Chem 1993;268:11119-24.
9. 3 production and amylase release in pancreatic acini. Am J Physiol 1994; 266:G363-71.
10. Swarup G, Cohen S, Garbers DL. Inhibition of membrane phosphotyrosyl-protein phosphatase activity by ortho-vanadate. Biochem Biophys Res Commun 1982;107:1104-19.
11. Secrist JP, Burns LA, Karnitz L, Koretzky GA, Abraham RT. Stimulatory effects of the protein tyrosine phosphatase inhibitor, perortho-vanadate, on T-cell activation events. J Biol Chem 1993;268:5886-93.
12. Dehaye JP, Grosfils K. Interaction of ortho-vanadate with isolated rat parotid acini. Gen Pharmacol 1993;24:479-88.
13. Pumiglia KM, Lau LF, Huang CK, Burroughs S, Feinstein MB. Activation of signal transduction in platelets by the tyrosine phosphatase inhibitor perortho-vanadate (vanadylhydroperoxide). Biochem J 1992;286:441-9.
14. Höcker M, Schmidt WE, Creutzfeldt W, Roy Choudhury A, Nustede R, Schafmayer A, et al. Determination of plasma CCK concentrations by bioassay and specific radioimmunoassay in man. A critical evaluation. Regul Pept 1992;37:255-69.
15. Kruse-Jarres JD, Kaiser C, Hafkenscheid JC, Hohenwallner W, Stein W, Bohner J, et al. PEvaluation of a new alpha-amylase assay using 4.6-ethylidene-(G7)-1-4-nitrophenyl-(G1)-alpha-D- maltoheptasoide as substrate. J Clin Chem Biochem 1989;27:103-5.
16. 2+ concentrations in the micromolar range, when provided with ATP and GTP-gamma-S. Biochem Biophys Acta 1990;1053:32-6.
17. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 1985;260:3440-50.
18. Theodorsson-Norheim E. Friedman and Quade tests: basic computer program to perform non-parametric two-way analysis of variance and multiple comparisons on ranks of several related samples. Comp Biol Med 1987;17:85-99.
19. 2+ and guanine nucleotides in exocytotic secretion from permeabilized rat mast cells. J Cell Biol 1987;105:191-7.
20. Gomperts BD, Tatham PER. Regulated exocytotic secretion from permeabilized cells. Methods Enzymol 1989;219:178-89.
21. Gomperts BD. GE: a GTP-binding protein mediating exocytosis. Annu Rev Physiol 1990;52:591-606.
22. Guan K, Haun RS, Watson SJ, Geahlen RL, Dixon JE. Cloning and expression of a protein-tyrosine-phosphatase. Proc Natl Acad Sci USA 1990;87:1501-5.
23. 2+-dependent amylase secretion from pancreatic acini. J Biol Chem 1991;266:17744-6.
24. Tonks NK, Diltz CD, Fischer EH. Charaterization of the major protein-tyrosine-phophatases of human placenta. J Biol Chem 1988;263:6722-30.
25. Shisheva A, Ikonomov O, Shechter Y. The protein tyrosine phosphatase inhibitor, perortho-vanadate, is a powerful anti- diabetogenic agent in streptozotozin-treated diabetic rats. Endocrinology 1994;134:507-10.
26. Fantus IG, Ahmad F, Deragon G. Ortho-vanadate augments insulin-stimulated insulin receptor kinase activity and prolongs insulin action in rat adipocytes. Evidence for transduction of amplitude of signaling into duration of response. Diabetes 1994;43:375-83.
27. Santini F, Beaven MA. Tyrosine phosphorylation of a mitogen-activated protein kinase-like protein occurs at a late step in exocytosis. J Biol Chem 1993;268:22716-22.
28. Fetz I, Meyer-Alber A, Fomefeld H, Höcker M, Fölsch UR, Schmidt WE. Protein tyrosine kinase and phosphatase inhibitors differentially modulate amylase secretion in rat pancreatic acinar cells. Gastroenterology 1994;106:A1210.
29. Meyer-Alber A, Fetz I, Fomefeld H, Waschulewski IH, Fölsch UR, Schmidt WE. Differential modulation of pancreatic enzyme secretion by protein kinase and phosphatase inhibitors. Digestion 1994;55:317-8.
30. Meyer-Alber A, Fomefeld H, Fölsch UR, Schmidt WE. Regulatorischer Einfluß des Tyrosinphosphatase-Inhibitors Vanadat auf die Stimulus-Sekretions-Kopplung an isolierten Pankreas-Azini der Ratte. Z Gastroenterol 1994;32:554.