Quantitative HPLC analysis of 4-[4-4(chlorophenyl)phenyl]-4-oxo-2s- (phenylthiomethyl) butanoic acid (bay 12-9566), a metalloproteinase inhibitor, and its metabolites in human plasma

Journal of Liquid Chromatography and Related Technologies

Volumn 22, Issue 12, 1999, Pages 1893-1906

  Agarwal, V K ^a   Rose, D L ^a   Krol, G J ^a  

^a BAYER CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [4,4 (CHLOROPHENYL)PHENYL] 4 OXO (PHENYLTHIOMETHYL)BUTANOIC ACID; BUTYRIC ACID; METALLOPROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ACCURACY; ANALYTIC METHOD; ARTICLE; DRUG BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; QUALITY CONTROL; QUANTITATIVE ASSAY; RADIATION DETECTION; TUMOR GROWTH;

EID: 0032989196     PISSN: 10826076     EISSN: None     Source Type: Journal    
DOI: 10.1081/JLC-100101774     Document Type: Article

References (11)

1. H. Birkedal-Hansen, W. G. I. Moore, M. K. Bodden, L. J. Windsor, B. Birkedal-Hansen, A. DeCarlo, J. A. Engler, Critical Reviews in Oral Biology and Medicine, 4(2), 197-250 (1993).
2. J. G. Conway, J. A. Wakefield, R. A. H. Brown, L. Sekut, S. A. Stimpson, A. McElroy, J. A. Menius, J. J. Jeffreys, R. L. Clark, G. M. McGeehan, K. M. Connolly, J. Exp. Med., 182(2), 449-457 (1995).
3. P. Koolwijk, A. M. Miltenburg, M. G. VanErck, M. Oudshoorn, M. J. Niedbala, F. C. Breedveld, V. W. VanHinsbergh, J. Rheumatol., 22(2), 385-393 (1995).
4. M. D. Johnson, H. R. Kim, L. Chesler, G. Tsao-Wu, N. Bouck, P. J. Polverini, J. Cell Physiol., 160(1), 194-202 (1994).
5. G. Taraboletti, A. Garofalo, D. Belotti, T. Drudis, P. Borsotti, E. Scanziani, P. D. Brown, R. Giavazzi, J. Natl. Cancer Inst., 87(4), 293-298 (1995).
6. C. Flynn, C. Bull, D. Eberwein, C. Matherne, B. Hibner, Proc. Am. Assoc. Cancer Res., 39, 301, Abs. 2057 (1998).
7. C. Bull, C. Flynn, D. Eberwein, A. M. Casazza, C. A. Carter, B. Hibner, Proc. Am. Assoc. Cancer Res., 39, 302, Abs. 2062 (1998).
8. B. Hibner, A. Card, C. Flynn, A. M. Casazza, G. Taraboletti, M. Rieppi, R. Giavazzi, Proc. Am. Assoc. Cancer Res., 39, 302, Abs. 2063 (1998).
9. H. Hirte, R. Goel, P. Major, B. Waterfield, S. Holohan, K. Bennett, A. Shah, I. Elias, L. Seymour, Proc. Am. Assoc. Cancer Res., 39, 364, Abs. 2484 (1998).
10. A. Shah, P. Sundaresan, R. Humphrey, A. H. Heller, Proc. Am. Assoc. Cancer Res., 39, 521, Abs. 3547 (1998).
11. R. Goel, H. Hirte, A. Shah, P. Major, B. Waterfield, S. Holohan, K. Bennett, I. Elias, L. Seymour, Proc. Clin. Oncology, 17, 217a, Abs. 240 (1998).