Effect of single versus multiple dosing on perfluorochemical distribution and elimination during partial liquid ventilation

Pediatric Pulmonology

Volumn 27, Issue 6, 1999, Pages 410-418

  Miller, Thomas F ^a   Milestone, Bart ^a   Stern, Robert ^a,b   Shaffer, Thomas H ^a   Wolfson, Marla R ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Acute lung injury; Animal studies; Distribution; Elimination; Neonatology; Partial liquid ventilation; Perfluorochemical; Respiratory distress syndrome; Treatment

Indexed keywords

PERFLUORO COMPOUND; PERFLUOROOCTYL BROMIDE;

ARTICLE; HUMAN; LUNG ALVEOLUS SURFACE TENSION; LUNG FUNCTION; LUNG VENTILATION DISTRIBUTION; LUNG VOLUME; PRIORITY JOURNAL; RABBIT; RESPIRATORY DISTRESS SYNDROME;

EID: 0032989146     PISSN: 87556863     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-0496(199906)27:6<410::AID-PPUL8>3.0.CO;2-5     Document Type: Article

References (28)

1. Shaffer TH, Rubenstein D, Moskowitz D, Delivoria-Papadopoulos M. Gaseous exchange and acid-base balance in premature lambs during liquid ventilation since birth. Pediatr Res 1976;10: 227-231.
2. Shaffer TH, Lowe CA, Bhutani VK, Douglas PR. Liquid ventilation: effects on pulmonary function in distressed meconiumstained lambs. Pediatr Res 1984;18:47-52.
3. Wolfson MR, Greenspan JS, Deoras KS, Rubenstein SD, Shaffer TH. Comparison of gas and liquid ventilation: clinical, physiological, and histological correlates. J Appl Physiol 1992;72: 1024-1031.
4. Wolfson MR, Tran N, Bhutani VK, Shaffer TH. A new experimental approach for the study of cardiopulmonary physiology during early development. J Appl Physiol 1988;65:1436-1443.
5. Leach CL, Holm B, Morin FC III, Fuhrman BP, Papo MC, Steinhorn D, Hernan LJ. Partial liquid ventilation in premature lambs with respiratory distress syndrome: efficacy and compatibility with exogenous surfactant. J Pediatr 1995;126:412-420.
6. Greenspan JS, Wolfson MR, Rubenstein SD, Shaffer TH. Liquid ventilation of human preterm neonates. J Pediatr 1990;117:106-111.
7. Leach CL, Greenspan JS, Rubenstein SD, Shaffer TH, Wolfson MR, Jackson JC, DeLemos R, Fuhrman BP, LiquiVent Study Group. Partial liquid ventilation with perflubron in premature infants with severe respiratory distress syndrome. N Engl J Med 1996;335:761-767.
8. Hirschl RB, Tooley R, Parent A, Johnson K, Bartlett RH. Evaluation of gas exchange, pulmonary compliance, and lung injury during total and partial liquid ventilation in the acute respiratory distress syndrome. Crit Care Med 1996;24:1001-1008.
9. Tutuncu AS, Akpir K, Mulder P, Erdmann W, Lachmann B. Intratracheal perfluorocarbon administration as an aid in the ventilatory management of respiratory distress syndrome. Anesthesiology 1993;79:1083-1093.
10. Gabriel JL, Miller TF, Wolfson MR. Shaffer TH. Quantitative structure-activity relationship of perfluorinated hetero-hydrocarbons as potential respiratory media: application to oxygen solubility, log P, viscosity, vapor pressure and density. ASAIO J 1996; 42:968-973.
11. Calderwood HW, Ruiz BC, Tham MK, Modell JH, Saga S, Hood CI. Residual levels and biochemical changes after ventilation with perfluorinated liquid. J Appl Physiol 1975;39:603-607.
12. Modell JH, Newby EJ, Ruiz BC. Long-term survival of dogs after breathing oxygenated fluorocarbon liquid. Fed Pro 1970;29:1731-1736.
13. Deoras KS, Coppola D, Wolfson MR, Greenspan JS, Rubenstein SD, Shaffer TH. Liquid ventilation of neonates: tissue histology and morphometry. Pediatr Res 1990;27:29.
14. Shaffer TH, Wolfson MR, Greenspan JS, Hoffman RE, Davis SL, Clark LC Jr. Liquid ventilation in premature lambs: uptake, bio-distribution and elimination of perfluorodecalin liquid. Reprod Fertil Dev 1996;8:409-416.
15. Wolfson MR, Greenspan JS, Shaffer TH. Pulmonary administration of vasoactive substances by perfluorochemical ventilation. Pediatrics 1996;97:449-455.
16. Zelinka MA, Wolfson MR, Calligaro S, Rubenstein SD, Greenspan JS, Shaffer TH. A comparison of intratracheal and intravenous administration of gentamicin during liquid ventilation. Eur J Pediatr 1996;156:401-404.
17. Thomas SR, Clark LC Jr, Ackerman JL, Pratt RG, Hoffman RE, Busse LJ, Kinsey RA, Samaratunga RC. MR imaging of the lung using liquid perfluorocarbons. J Comput Assist Tomogr 1986;10: 1-9.
18. Stern RG, Wolfson MR, McGuckin JF, Forge JA, Shaffer TH. High-resolution computed tomographic bronchiolography using perfluoroctylbromide (PFOB): an experimental model. J Thorac Imaging 1993;8:300-304.
19. Wolfson MR, Stern RG, Kechner N, Sekins KM, Shaffer TH. Utility of a perfluorochemical liquid for pulmonary diagnostic imaging. Art Cells Blood Subs Immob Biotech 1994;22:1409-1420.
20. Richman PS, Wolfson MR, Shaffer TH. Lung lavage with oxygenated perfluorochemical liquid in acute lung injury. Crit Care Med 1993;21:768-774.
21. Fuhrman BP, Paczan PR, DeFrancisis M. Perfluorocarbon-associated gas exchange. Crit Care Med 1991;19:712-722.
22. Salman NH, Fuhrman BP, Steinhorn DM, Papp MC, Hernan LJ, Leach CL, Fischer JE. Prolonged studies of perfluorocarbon associated gas exchange and of the resumption of conventional mechanical ventilation. Crit Care Med 1995;23:919-924.
23. Shaffer TH, Foust R, Wolfson MR, Miller TF Jr. Analysis of perfluorochemical elimination from the respiratory system. J Appl Physiol 1997;83:1033-1040.
24. Tarczy-Hornoch P, Hildebrandt J, Mates EA, Standaert TA, Lamm WJE, Jackson JC. Effects of exogenous surfactant on lung pressure-volume characteristics during liquid ventilation. J Appl Physiol 1996;80:1764-1771.
25. Weers J, Johnson C. Equilibrium spreading coefficients of perfluorocarbons. Alliance Pharmaceutical Corp. 1991; Res and Dev Report: June.
26. Shaffer TH, Douglas PR, Lower CA, Bhutani VK. The effect of liquid ventilation on cardiopulmonary function in preterm lambs. Pediatr Res 1983;17:303-306.
27. Tutuncu AS, Houmes RJM, Bos JAH, Wollmer P, Lachmann B. Evaluation of lung function after intratracheal perfluorocarbon administration in healthy animals. Crit Care Med 1996;24:274-279.
28. Gross GW, Greeenspan JS, Fox WW, Rubenstein SD, Wolfson MR, Shaffer TH. Use of liquid ventilation with perflubron during extracorporeal membrane oxygenation: Chest radiographic appearances. Radiology 1995;194:717-720.