Distribution of ciprofloxacin into the central nervous system in rats with acute renal or hepatic failure

Journal of Pharmacy and Pharmacology

Volumn 51, Issue 5, 1999, Pages 609-616

  Naora, Kohji ^a   Ichikawa, Nobuhiro ^a   Hirano, Hidenari ^a   Iwamoto, Kikuo ^a  

^a SHIMANE UNIVERSITY HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON TETRACHLORIDE; CIPROFLOXACIN; URANYL NITRATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; CENTRAL NERVOUS SYSTEM; CONFERENCE PAPER; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY FAILURE; LIVER FAILURE; MALE; NONHUMAN; RAT;

EID: 0032988383     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357991772718     Document Type: Conference Paper

References (27)

1. Borner, K., Höffken, G., Lode, H., Koeppe, P., Prinzing, C., Glatzel, P., Wiley, R., Olschewski, P., Sievers, B., Reinitz, D. (1986) Pharmacokinetics of ciprofloxacin in healthy volunteers after oral and intravenous administration. Eur. J. Clin. Microbiol. 5: 179-186
2. Chen, H. S., Gross, J. F. (1979) Estimation of tissue-to-plasma partition coefficients used in physiological pharmacokinetic models. J. Pharmacokinet. Biopharm. 7: 117-125
3. Christ, W. (1990) Central nervous system toxicity of quinolones: human and animal findings. J. Antimicrob. Chemother. 26: 219-225
4. Frost, R. W., Lettieri, J. T., Krol, G., Shamblen, E. C., Lasseter, K. C. (1989) The effect of cirrhosis on the steady-state pharmacokinetics of oral ciprofloxacin. Clin. Pharmacol. Ther. 45: 608-616
5. Giacomini, K. M., Roberts, S. M., Levy, G. (1981) Evaluation of methods for producing renal dysfunction in rats. J. Pharm. Sci. 70: 117-121
6. Höffken, G., Lode, H., Prinzing, C., Borner, K., Koeppe, P. (1985) Pharmacokinetics of ciprofloxacin after oral and parenteral administration. Antimicrob. Agents Chemother. 27: 375-379
7. Janknegt, R. (1986) Fluorinated quinolones. A review of their mode of action, antimicrobial activity, pharmacokinetics and clinical efficacy. Pharm. Weekbl. Sci. Ed. 8: 1-21
8. Katagiri, Y., Naora, K., Ichikawa, N., Hayashibara, M., Iwamoto, K. (1990) High-performance liquid chromatographic determination of ciprofloxacin in rat brain and cerebrospinal fluid. Chem. Pharm. Bull. 38: 2884-2886
9. Lam, Y. W. F., Banerji, S., Hatfield, C., Talbert, R. L. (1997) Principles of drug administration in renal insufficiency. Clin. Pharmacokinet. 32: 30-57
10. Lin, T. H., Lin, J. H. (1990) Effects of protein binding and experimental disease states on brain uptake of benzodiazepines in rats. J. Pharmacol. Exp. Ther. 253: 45-50
11. Lin, J. H., Sugiyama, Y., Awazu, S., Hanano, M. (1982) Physiological pharmacokinetics of ethoxybenzamide based on biochemical data obtained in vitro as well as on physiological data. J. Pharmacokinet. Biopharm. 10: 649-661
12. Lin, T. H., Sawada, Y., Sugiyama, Y., Iga, T., Hanano, M. (1987) Inhibition of blood-brain barrier permeability to DL-propranolol by serum from acute renal failure rats. Biochem. Pharmacol. 36: 3425-3431
13. Lo, W. D., Ennis, S. R., Goldstein, G. W., McNeely, D. L., Betz, A. L. (1987) The effects of galactosamine-induced hepatic failure upon blood-brain barrier permeability. Hepatology 7: 452-456
14. Mingrone, G., De Smet, R., Greco, A. V., Bertuzzi, A., Gandolfi, A., Ringoir, S., Vanholder, R. (1997) Serum uremic toxins from patients with chronic renal failure displace the binding of L-tryptophan to human serum albumin. Clin. Chim. Acta 260: 27-34
15. Montay, G., Gaillot, J. (1990) Pharmacokinetics of fluoroquinolones in hepatic failure. J. Antimicrob. Chemother. 26: 61-67
16. Naora, K., Katagiri, Y., Ichikawa, N., Hayashibara, M., Iwamoto, K. (1990) A possible reduction in the renal clearance of ciprofloxacin by fenbufen in rats. J. Pharm. Pharmacol. 42: 704-707
17. Naora, K., Katagiri, Y., Ichikawa, N., Hayashibara, M., Iwamoto, K. (1991) Enhanced entry of ciprofloxacin into the rat central nervous system induced by fenbufen. J. Pharmacol. Exp. Ther. 258: 1033-1037
18. Nouaille-Degorce, B., Veau, C., Dautrey, S., Tod, M., Laouari, D., Carbon, C., Farinotti, R. (1998) Influence of renal failure on ciprofloxacin pharmacokinetics in rats. Antimicrob. Agents Chemother. 42: 289-292
19. Ooie, T., Suzuki, H., Terasaki, T., Sugiyama, Y. (1996) Kinetics of quinolone antibiotics in rats: efflux from cerebrospinal fluid to the circulation. Pharm. Res. 13: 1065-1068
20. Ooie, T., Terasaki, T., Suzuki, H., Sugiyama, Y. (1997) Kinetic evidence for active efflux transport across the blood-brain barrier of quinolone antibiotics. J. Pharmacol. Exp. Ther. 283: 293-304
21. Ramirez, C. A., Bran, J. L., Mejia, C. R., Garcia, J. F. (1985) Open, prospective study of the clinical efficacy of ciprofloxacin. Antimicrob. Agents Chemother. 28: 128-132
22. Shimokawa, M., Yamamoto, K., Kawakami, J., Sawada, Y., Iga, T. (1994) Effect of renal or hepatic dysfunction on neurotoxic convulsion induced by ranitidine in mice. Pharm. Res. 11: 1519-1523
23. 14C]ciprofloxacin in albino rats and rhesus monkeys. Arzneim. Forsch. 36: 1496-1502
24. Upton, R. A. (1975) Simple and reliable method for serial sampling of blood from rats. J. Pharm. Sci. 64: 112-114
25. Vance-Bryan, K., Guay, D. R., Rotschafer, J. C. (1990) Clinical pharmacokinetics of ciprofloxacin. Clin. Pharmacokinet. 19: 434-461
26. Wolfson, J. S., Hooper, D. C. (1985) The fluoroquinolones: structures, mechanisms of action and resistance, and spectra of activity in vitro. Antimicrob. Agents Chemother. 28: 581-586
27. Yamaoka, K., Tanigawara, Y., Nakagawa, T., Uno, T. (1981) A pharmacokinetic analysis program (multi) for microcomputer. J. Pharmacobiodyn. 4: 879-885