Nuclear targeting of plasmid DNA in human corneal cells

Current Eye Research

Volumn 19, Issue 1, 1999, Pages 66-75

  Dean, David A ^a   Byrd Jr , James N ^b   Dean, Brenda S ^b  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

^b NONE

Author keywords

Gene therapy; Gene transfer; Human corneal epithelial cells; Keratocytes; Nuclear transport

Indexed keywords

BETA GALACTOSIDASE; LIPOSOME; LUCIFERASE; PLASMID DNA; TRANSCRIPTION FACTOR; VIRUS VECTOR;

ARTICLE; BINDING SITE; CELL CULTURE; CELL NUCLEUS; CONTROLLED STUDY; CORNEA; CORNEA CELL; CORNEA EPITHELIUM; CYTOPLASM; DNA SEQUENCE; ENHANCER REGION; GENE EXPRESSION; GENE TARGETING; GENE THERAPY; GENE TRANSFER; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; MICROINJECTION; MITOSIS; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; SIMIAN VIRUS 40;

BASE SEQUENCE; BIOLOGICAL TRANSPORT; CELL NUCLEUS; CELLS, CULTURED; CORNEA; DNA; DNA, VIRAL; ENHANCER ELEMENTS (GENETICS); EPITHELIAL CELLS; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; HUMANS; LIPOSOMES; MICROINJECTIONS; PLASMIDS; PROMOTER REGIONS (GENETICS); SIMIAN VIRUS 40; TRANSFECTION;

EID: 0032987674     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.1076/ceyr.19.1.66.5344     Document Type: Article

References (29)

1. Mashhour B, Couton D, Perricaudet M, Briand P. In vivo adenovirus-mediated gene transfer into ocular tissues. Gene Therapy. 1994;1:122-126.
2. Borrás T, Tamm ER, Zigler JS. Ocular Adenovirus gene tranfser varies in efficiency and inflammatory response. Invest. Ophthalmol. Vis. Sci. 1996;37:1282-1293.
3. Budenz DL, Bennett J, Alonso L, Maguire A. In vivo gene transfer into murine corneal endothelial and trabecular meshwork cells. Invest. Ophthal. Vis. Sci. 1995; 36:2211-2215.
4. Chung DC, Anglade E, Sullivan DM, Nussenblatt RB, Csaky KG. Comparison of lipofection, calcium phosphate coprecipitation and adenovirus facilitated lipofection mediated ex vivo gene transfer into cultured human retinal pigment epithelial cells. Invest. Ophthalmol. Vis. Sci. 1996;37:S9.
5. Matsuo T, Masuda I, Yasuda T, Matsuo N. Gene transfer to the retina of rat by liposome eye drops. Biochem. Biophys. Res. Comm. 1996;219:947-950.
6. Masuda I, Matsuo T, Yasuda T, Matsuo N. Gene transfer with liposomes to the intracoular tissues by different routes of administration. Invest. Ophthalmol. Vis. Sci. 1996;37:1914-1920.
7. Anderson WF. Human gene therapy. Science. 1992;256: 808-813.
8. Mulligan RC. The basic science of gene therapy. Science. 1993;260:926-932.
9. Miller DG, Adam MA, Miller AD. Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection. Mol. Cell Biol. 1990:10:4239-4242.
10. Lewis PF, Emerman M. Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virus. J. Virol. 1994;68:510-516.
11. Murphy C, Alvarado J, Juster R. Maglio M. Prenatal and postnatal cellularity of the corneal endothelium. Invest. Ophthal. 1984;25:312-322.
12. Dean DA. Import of plasmid DNA into the nucleus is sequence specific. Exp. Cell Res. 1997;230:293-302.
13. Nigg EA. Nucleocytoplasmic transport: signals, mechanisms and regulation. Nature. 1997;386:779-787.
14. Dowty ME, Williams P, Zhang G, Hagstrom JE, Wolff JA. Plasmid DNA entry into postmitotic nuclei of primary rat myotubes. Proc. Natl. Acad. Sci. USA. 1995;92: 4572-4576.
15. Cubitt CL, Tang Q, Monteiro CA, Lausch RN, Oakes JE. IL-8 gene expression in cultures of human corneal epithelial cells and keratocytes. Invest. Ophthalmol. Vis. Sci. 1993;34:3199-3206.
16. Tran MT, Dean DA, Lausch RN, Oakes JE. Membranes of herpes simplex virus type-1-infected human corneal epithelial cells are not permeabilized to macromolecules and therefore do not release IL-1α. Virology. 1998;244: 74-78.
17. Dean DA, Li PL, Lee LM, Kasamatsu H. Essential role of the Vp2 and Vp3 DNA-binding domain in SV40 morphogenesis. J. Virol. 1995;69:1115-1121.
18. DeLucia AL, Deb S, Partin K, Tegtmeyer P. Functional interactions of the simian virus 40 core origin of replication with flanking regulatory sequences. J. Virol. 1986;57:138-144.
19. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K. Current protocols in molecular biology. New York: John Wiley & Sons; 1994.
20. Graessman M, Graessman A. Microinjection of tissue culture cells using glass microcapillaries: methods. In: J. E. Celis, A. Graessmann and A. Loyter, eds. Microinjection and organelle transplantation techniques: methods and applications. London: Academic Press; 1986:3-37.
21. Johnson CV, Singer RH, Lawrence JB. Fluorescent detection of nuclear RNA and DNA: Implications for genome organization. Meth. Cell Biol. 1991;35:73-99.
22. Balczon R, Bao L, Zimmer WE. PCM-1, A 228-kD centrosome autoantigen with a distinct cell cycle distribution. J Cell Biol. 1994;124:783-93.
23. Ikegami S, Taguchi T, Ohashi M, Oguro M, Nagano H, Mano Y. Aphidicolin prevents mitotic cell division by interfering with the activity of DNA polymerase-alpha. Nature. 1978;275:458-60.
24. Werner M, Madreperla S, Lieberman P, Adler R. Expression of transfected genes by differentiated, postmitotic neurons and photoreceptors in primary cell cultures. J Neurosci Res. 1990;25:50-7.
25. Cole CN. Polyomavirinae: the viruses and their replication. In: B. N. Fields, D. M. Knipe, P. M. Howley, R. M. Chanock, J. L. Melnick, T. P. Monath, B. Roizman and S. E. Staus, eds. Virology. 3rd ed. New York: Raven Press; 1996:1997-2043.
26. Wingender E, Kel AE, Kel OV, Karas H, Heinemeyer T, Dietze P, Knueppel R, Romaschenko AG, Kolchanov NA. TRANSFAC, TRRD and COMPEL: Towards a federated database system on transcriptional regulation. Nucleic Acids Res. 1997;25:265-268.
27. Thierry AR, Rabinovich P, Peng B, Mahan LC, Bryant JL, Gallo RC. Characterization of liposome-mediated gene delivery: expression, stability and pharmacokinetics of plasmid DNA. Gene Ther. 1997;4:226-37.
28. Stamminger T, Fickenscher H, Fleckenstein B. Cell type-specific induction of the major immediate early enhancer of human cytomegalovirus by cyclic AMP [published erratum appears in J Gen Virol 1990 Jul;71(Pt 7):1627]. J Gen Virol 1990;71:105-13.
29. Tooze J. Molecular biology of tumor viruses, 2nd edition. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory; 1980.