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Volumn 16, Issue 2, 1999, Pages 122-133

Coronary heart disease: At the interface of molecular genetics and preventive medicine

Author keywords

Cardiovascular diseases; Chemical and pharmacologic phenomena; Coronary disease; Pharmacogenetics; Polymorphism (genetics); Risk factors

Indexed keywords

ARTICLE; DISEASE PREDISPOSITION; EARLY DIAGNOSIS; ENVIRONMENTAL FACTOR; EPISTASIS; HUMAN; HYPERCHOLESTEROLEMIA; ISCHEMIC HEART DISEASE; MOLECULAR GENETICS; PREVENTIVE MEDICINE; PUBLIC HEALTH; SMOKING CESSATION;

EID: 0032987566     PISSN: 07493797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0749-3797(98)00138-X     Document Type: Article
Times cited : (39)

References (87)
  • 1
    • 0345090587 scopus 로고
    • Report of the task force on research in epidemiology and prevention of cardiovascular diseases
    • Report of the task force on research in epidemiology and prevention of cardiovascular diseases. National Institutes of Health. August. 1994.
    • (1994) National Institutes of Health. August
  • 2
    • 0027994593 scopus 로고
    • Established risk factors and coronary artery disease: The Framingham study
    • Wilson P.W.F. Established risk factors and coronary artery disease the Framingham study . Am J Hypertens. 7:1994;7S-12S.
    • (1994) Am J Hypertens , vol.7
    • Wilson, P.W.F.1
  • 3
    • 0024970667 scopus 로고
    • Relation between family history of coronary artery disease and coronary risk variables
    • Perkins K.A. Relation between family history of coronary artery disease and coronary risk variables. Am J Cardiol. 63:1989;1539.
    • (1989) Am J Cardiol , vol.63 , pp. 1539
    • Perkins, K.A.1
  • 4
    • 0002230202 scopus 로고
    • Familial hypercholesterolemia
    • C.R. Scriver, A.L. Beaudet, W.S. Sly, & D. Valle. New York: McGraw-Hill, Inc
    • Goldstein J.L., Brown M.S. Familial hypercholesterolemia. Scriver C.R., Beaudet A.L., Sly W.S., Valle D. The metabolic basis of inherited disease. 1989;1215-1250 McGraw-Hill, Inc, New York.
    • (1989) The Metabolic Basis of Inherited Disease , pp. 1215-1250
    • Goldstein, J.L.1    Brown, M.S.2
  • 5
    • 0026633925 scopus 로고
    • Hyperhomocyst(e)inemia as a risk factor for occlusive vascular disease
    • Kang S.-S., Wong P.W.K., Malinow M.R. Hyperhomocyst(e)inemia as a risk factor for occlusive vascular disease. Annu Rev Nutr. 12:1992;279-298.
    • (1992) Annu Rev Nutr , vol.12 , pp. 279-298
    • Kang, S.-S.1    Wong, P.W.K.2    Malinow, M.R.3
  • 6
    • 0027431375 scopus 로고
    • Identification and management of heterozygous familial hypercholesterolemia: Summary and recommendations from an NHLBI workshop
    • Bild D.E., Williams R.R., Brewer H.B., Herd J.A., Pearson T.A., Stein E. Identification and management of heterozygous familial hypercholesterolemia summary and recommendations from an NHLBI workshop . Am J Cardiol. 72:1993;1D-5D.
    • (1993) Am J Cardiol , vol.72
    • Bild, D.E.1    Williams, R.R.2    Brewer, H.B.3    Herd, J.A.4    Pearson, T.A.5    Stein, E.6
  • 7
    • 0029683307 scopus 로고    scopus 로고
    • Genetic architecture of common multifactorial diseases
    • D. Chadwick, & G. Cardew. Chichester, England: John Wiley and Sons
    • Sing C.F., Haviland M.B., Reilly S.L. Genetic architecture of common multifactorial diseases. Chadwick D., Cardew G. Variation in the human genome. 1996;211-232 John Wiley and Sons, Chichester, England.
    • (1996) Variation in the Human Genome , pp. 211-232
    • Sing, C.F.1    Haviland, M.B.2    Reilly, S.L.3
  • 8
    • 0023788909 scopus 로고
    • DNA polymorphisms of the apolipoprotein genes-their use in the investigation of the genetic component of hyperlipidaemia and atherosclerosis
    • Humphries S.E. DNA polymorphisms of the apolipoprotein genes-their use in the investigation of the genetic component of hyperlipidaemia and atherosclerosis. Atherosclerosis. 72:1988;89-108.
    • (1988) Atherosclerosis , vol.72 , pp. 89-108
    • Humphries, S.E.1
  • 9
    • 0026669336 scopus 로고
    • Molecular basis of human hypertension: Role of angiotensinogen
    • Jeunemaître X., Soubrier F., Kotelevtsev Y.V., et al. Molecular basis of human hypertension role of angiotensinogen . Cell. 71:1992;169-180.
    • (1992) Cell , vol.71 , pp. 169-180
    • Jeunemaître, X.1    Soubrier, F.2    Kotelevtsev, Y.V.3
  • 10
    • 0029984438 scopus 로고    scopus 로고
    • Genotype-environment interaction: Apolipoprotein E (apoE) gene effects and age as an index of time and spatial context in the human
    • Zerba K.E., Ferrell R.E., Sing C.F. Genotype-environment interaction apolipoprotein E (apoE) gene effects and age as an index of time and spatial context in the human . Genetics. 143:1996;463-478.
    • (1996) Genetics , vol.143 , pp. 463-478
    • Zerba, K.E.1    Ferrell, R.E.2    Sing, C.F.3
  • 11
    • 0028028061 scopus 로고
    • The gender-specific apolipoprotein E genotype influence on the distribution of plasma lipids and apolipoproteins in the population of Rochester, MN. III. Correlations and covariances
    • Reilly S.L., Ferrell R.E., Sing C.F. The gender-specific apolipoprotein E genotype influence on the distribution of plasma lipids and apolipoproteins in the population of Rochester, MN. III. Correlations and covariances. Am J Hum Genet. 55:1994;1001-1018.
    • (1994) Am J Hum Genet , vol.55 , pp. 1001-1018
    • Reilly, S.L.1    Ferrell, R.E.2    Sing, C.F.3
  • 12
    • 0024342063 scopus 로고
    • Plasma homocysteine, a risk factor for vascular disease: Plasma levels in health, disease, and drug therapy
    • Ueland P.M., Refsum H. Plasma homocysteine, a risk factor for vascular disease plasma levels in health, disease, and drug therapy . J Lab Clin Med. 114:1989;473-501.
    • (1989) J Lab Clin Med , vol.114 , pp. 473-501
    • Ueland, P.M.1    Refsum, H.2
  • 13
    • 0031023815 scopus 로고    scopus 로고
    • Pharmacogenetics: A laboratory tool for optimizing therapeutic efficiency
    • Linder M.W., Prough R.A., Valdes R. Jr. Pharmacogenetics a laboratory tool for optimizing therapeutic efficiency . Clin Chem. 43:1997;254-266.
    • (1997) Clin Chem , vol.43 , pp. 254-266
    • Linder, M.W.1    Prough, R.A.2    Valdes R., Jr.3
  • 14
    • 0001873889 scopus 로고
    • Apolipoprotein E polymorphism and atherosclerosis
    • In: Born GVR, Schwartz CJ, editors London, UK: Science Press Ltd.
    • Davignon J. Apolipoprotein E polymorphism and atherosclerosis. In: Born GVR, Schwartz CJ, editors. New horizons in coronary heart disease. London, UK: Science Press Ltd., 1993;5.1-5.21.
    • (1993) New Horizons in Coronary Heart Disease , pp. 51-521
    • Davignon, J.1
  • 15
    • 0019433761 scopus 로고
    • Human very low density lipoprotein apolipoprotein E isoprotein polymorphism is explained by genetic variation and posttranslational modification
    • Zannis V.I., Breslow J.L. Human very low density lipoprotein apolipoprotein E isoprotein polymorphism is explained by genetic variation and posttranslational modification. Biochemistry. 20:1981;1033-1041.
    • (1981) Biochemistry , vol.20 , pp. 1033-1041
    • Zannis, V.I.1    Breslow, J.L.2
  • 17
    • 0023878396 scopus 로고
    • Simultaneous effects of the apolipoprotein E polymorphism on apolipoprotein E, apolipoprotein B, and cholesterol metabolism
    • Boerwinkle E., Utermann G. Simultaneous effects of the apolipoprotein E polymorphism on apolipoprotein E, apolipoprotein B, and cholesterol metabolism. Am J Hum Genet. 42:1988;104-112.
    • (1988) Am J Hum Genet , vol.42 , pp. 104-112
    • Boerwinkle, E.1    Utermann, G.2
  • 18
    • 0025820743 scopus 로고
    • Pathobiological Determinants of Atherosclerosis in Youth Research Group. Apolipoprotein E polymorphisms affect atherosclerosis in young males
    • Hixson J.E. Pathobiological Determinants of Atherosclerosis in Youth Research Group. Apolipoprotein E polymorphisms affect atherosclerosis in young males. Arterioscler Thromb. 11:1991;1237-1244.
    • (1991) Arterioscler Thromb , vol.11 , pp. 1237-1244
    • Hixson, J.E.1
  • 20
    • 0026594925 scopus 로고
    • Lipoproteins and their genetic variation in subjects with and without angiographically verified coronary artery disease
    • Nieminen M.S., Mattila K.J., Aalto-Setälä K., et al. Lipoproteins and their genetic variation in subjects with and without angiographically verified coronary artery disease. Arterioscler Thromb. 12:1992;58-69.
    • (1992) Arterioscler Thromb , vol.12 , pp. 58-69
    • Nieminen, M.S.1    Mattila, K.J.2    Aalto-Setälä, K.3
  • 22
    • 0001308022 scopus 로고
    • The kallikrein-kinin system as a regulator of cardiovascular and renal function
    • J.H. Laragh, & B.M. Brenner. New York: Raven Press, Ltd
    • Carretero O.A., Scicli A.G. The kallikrein-kinin system as a regulator of cardiovascular and renal function. Laragh J.H., Brenner B.M. Hypertension: Pathophysiology, diagnosis, and management. 1995;983-999 Raven Press, Ltd, New York.
    • (1995) Hypertension: Pathophysiology, Diagnosis, and Management , pp. 983-999
    • Carretero, O.A.1    Scicli, A.G.2
  • 23
    • 0025165779 scopus 로고
    • An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels
    • Rigat B., Hubert C., Alhenc-Gelas F., Cambien F., Corvol P., Soubrier F. An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest. 86:1990;1343-1346.
    • (1990) J Clin Invest , vol.86 , pp. 1343-1346
    • Rigat, B.1    Hubert, C.2    Alhenc-Gelas, F.3    Cambien, F.4    Corvol, P.5    Soubrier, F.6
  • 24
    • 0029988937 scopus 로고    scopus 로고
    • Identification of new polymorphisms of the angiotensin I-converting enzyme (ACE) gene, and study of their relationship to plasma ACE levels by two-QTL segregation-linkage analysis
    • Villard E., Tiret L., Visvikis S., Rakotovao R., Cambien F., Soubrier F. Identification of new polymorphisms of the angiotensin I-converting enzyme (ACE) gene, and study of their relationship to plasma ACE levels by two-QTL segregation-linkage analysis. Am J Hum Genet. 58:1996;1268-1278.
    • (1996) Am J Hum Genet , vol.58 , pp. 1268-1278
    • Villard, E.1    Tiret, L.2    Visvikis, S.3    Rakotovao, R.4    Cambien, F.5    Soubrier, F.6
  • 25
    • 0029814043 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme gene polymorphism: What to do about all the confusion?
    • Singer D.R.J., Missouris C.G., Jeffery S. Angiotensin-converting enzyme gene polymorphism what to do about all the confusion? Circulation. 94:1996;236-239.
    • (1996) Circulation , vol.94 , pp. 236-239
    • Singer, D.R.J.1    Missouris, C.G.2    Jeffery, S.3
  • 26
    • 0030699918 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme gene polymorphism and cardiovascular disease
    • Butler R., Morris A.D., Struthers A.D. Angiotensin-converting enzyme gene polymorphism and cardiovascular disease. Clin Sci. 93:1997;391-400.
    • (1997) Clin Sci , vol.93 , pp. 391-400
    • Butler, R.1    Morris, A.D.2    Struthers, A.D.3
  • 27
    • 0029738658 scopus 로고    scopus 로고
    • A meta-analysis of the association of the deletion allele of the angiotensin-converting enzyme gene with myocardial infarction
    • Samani N.J., Thompson J.R., O'Toole L., Channer K., Woods K.L. A meta-analysis of the association of the deletion allele of the angiotensin-converting enzyme gene with myocardial infarction. Circulation. 94:1996;708-712.
    • (1996) Circulation , vol.94 , pp. 708-712
    • Samani, N.J.1    Thompson, J.R.2    O'Toole, L.3    Channer, K.4    Woods, K.L.5
  • 28
    • 0000443712 scopus 로고
    • Inherited disorders of folate transport and metabolism
    • C.R. Scriver, A.L. Beaudet, W.S. Sly, & D. Valle. New York: McGraw-Hill, Inc
    • Rosenblatt D.S. Inherited disorders of folate transport and metabolism. Scriver C.R., Beaudet A.L., Sly W.S., Valle D. The metabolic and molecular bases of inherited disease. 1995;3111-3128 McGraw-Hill, Inc, New York.
    • (1995) The Metabolic and Molecular Bases of Inherited Disease , pp. 3111-3128
    • Rosenblatt, D.S.1
  • 29
    • 0040344488 scopus 로고    scopus 로고
    • TM. Baltimore, MD. Johns Hopkins University. MIM Number 236200. Last edited 12 January World Wide Web
    • TM. Baltimore, MD. Johns Hopkins University. MIM Number 236200. Last edited 12 January 1998. World Wide Web URL: http://www.ncbi.nlm.nih.gov/omim.
    • (1998) Online Mendelian Inheritance in Man
  • 30
    • 0030971062 scopus 로고    scopus 로고
    • Homocysteine and thrombotic disease
    • D'Angelo A., Selhub J. Homocysteine and thrombotic disease. Blood. 90:1997;1-11.
    • (1997) Blood , vol.90 , pp. 1-11
    • D'Angelo, A.1    Selhub, J.2
  • 31
    • 0030188563 scopus 로고    scopus 로고
    • The oxidant stress of hyperhomocyst(e)inemia
    • Loscalzo J. The oxidant stress of hyperhomocyst(e)inemia. J Clin Invest. 98:1996;5-7.
    • (1996) J Clin Invest , vol.98 , pp. 5-7
    • Loscalzo, J.1
  • 32
    • 0029066299 scopus 로고
    • A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes
    • Boushey C.J., Beresford S.A.A., Omenn G.S., Motulsky A.G. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. JAMA. 274:1995;1049-1057.
    • (1995) JAMA , vol.274 , pp. 1049-1057
    • Boushey, C.J.1    Beresford, S.A.A.2    Omenn, G.S.3    Motulsky, A.G.4
  • 33
    • 0032501963 scopus 로고    scopus 로고
    • 6 concentrations: Risk factors for stroke, peripheral vascular disease, and coronary artery disease
    • 6 concentrations risk factors for stroke, peripheral vascular disease, and coronary artery disease . Circulation. 97:1998;437-443.
    • (1998) Circulation , vol.97 , pp. 437-443
    • Robinson, K.1    Arheart, K.2    Refsum, H.3
  • 34
    • 0032555096 scopus 로고    scopus 로고
    • Homocysteine, vitamins, and cardiovascular disease (editorial)
    • Kuller L.H., Evans R.W. Homocysteine, vitamins, and cardiovascular disease (editorial). Circulation. 98:1998;196-199.
    • (1998) Circulation , vol.98 , pp. 196-199
    • Kuller, L.H.1    Evans, R.W.2
  • 35
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
    • Frosst P., Blom H.J., Milos R., et al. A candidate genetic risk factor for vascular disease a common mutation in methylenetetrahydrofolate reductase . Nat Genet. 10:1995;111-113.
    • (1995) Nat Genet , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3
  • 36
    • 0029655527 scopus 로고    scopus 로고
    • Nutritional ecogenetics: Homocysteine-related arteriosclerotic vascular disease, neural tube defects, and folic acid
    • Motulsky A.G. Nutritional ecogenetics homocysteine-related arteriosclerotic vascular disease, neural tube defects, and folic acid . Am J Hum Genet. 58:1996;17-20.
    • (1996) Am J Hum Genet , vol.58 , pp. 17-20
    • Motulsky, A.G.1
  • 37
    • 0030897112 scopus 로고    scopus 로고
    • Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease
    • Morita H., Taguchi J., Kurihara H., et al. Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease. Circulation. 95:1997;2032-2036.
    • (1997) Circulation , vol.95 , pp. 2032-2036
    • Morita, H.1    Taguchi, J.2    Kurihara, H.3
  • 38
    • 0030826587 scopus 로고    scopus 로고
    • Thermolabile methylenetetrahydrofolate reductase in coronary artery disease
    • Kluijtmans L.A., Kastelein J.J., Lindemans J., et al. Thermolabile methylenetetrahydrofolate reductase in coronary artery disease. Circulation. 96:1997;2573-2577.
    • (1997) Circulation , vol.96 , pp. 2573-2577
    • Kluijtmans, L.A.1    Kastelein, J.J.2    Lindemans, J.3
  • 39
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell. 72:1993;971-983.
    • (1993) Cell , vol.72 , pp. 971-983
  • 40
    • 0024423668 scopus 로고
    • Identification of the cystic fibrosis gene: Genetic analysis
    • Kerem B., Rommens J.M., Buchanan J.A., et al. Identification of the cystic fibrosis gene genetic analysis . Science. 245:1989;1073-1080.
    • (1989) Science , vol.245 , pp. 1073-1080
    • Kerem, B.1    Rommens, J.M.2    Buchanan, J.A.3
  • 41
    • 0026673938 scopus 로고
    • Gene-environment interactions in atherosclerosis
    • Hegele R.A. Gene-environment interactions in atherosclerosis. Mol Cell Biochem. 113:1992;177-186.
    • (1992) Mol Cell Biochem , vol.113 , pp. 177-186
    • Hegele, R.A.1
  • 42
    • 0028290165 scopus 로고
    • Angiotensin II type 1 receptor gene polymorphisms in human essential hypertension
    • Bonnardeaux A., Davies E., Jeunemaître X., et al. Angiotensin II type 1 receptor gene polymorphisms in human essential hypertension. Hypertension. 24:1994;63-69.
    • (1994) Hypertension , vol.24 , pp. 63-69
    • Bonnardeaux, A.1    Davies, E.2    Jeunemaître, X.3
  • 43
    • 0027968353 scopus 로고
    • Synergistic effects of angiotensin-converting enzyme and angiotensin-II type 1 receptor gene polymorphisms on risk of myocardial infarction
    • Tiret L., Bonnardeaux A., Poirier O., et al. Synergistic effects of angiotensin-converting enzyme and angiotensin-II type 1 receptor gene polymorphisms on risk of myocardial infarction. Lancet. 344:1994;910-913.
    • (1994) Lancet , vol.344 , pp. 910-913
    • Tiret, L.1    Bonnardeaux, A.2    Poirier, O.3
  • 44
    • 0026734022 scopus 로고
    • The gender-specific apolipoprotein E genotype influence on the distribution of plasma lipids and apolipoproteins in the population of Rochester, Minnesota. II. Regression relationships with concomitants
    • Reilly S.L., Ferrell R.E., Kottke B.A., Sing C.F. The gender-specific apolipoprotein E genotype influence on the distribution of plasma lipids and apolipoproteins in the population of Rochester, Minnesota. II. Regression relationships with concomitants. Am J Hum Genet. 51:1992;1311-1324.
    • (1992) Am J Hum Genet , vol.51 , pp. 1311-1324
    • Reilly, S.L.1    Ferrell, R.E.2    Kottke, B.A.3    Sing, C.F.4
  • 45
    • 0030863012 scopus 로고    scopus 로고
    • Evidence that the apolipoprotein E-genotype effects on lipid levels can change with age in males: A longitudinal analysis
    • Jarvik G.P., Goode E.L., Austin M.A., et al. Evidence that the apolipoprotein E-genotype effects on lipid levels can change with age in males a longitudinal analysis . Am J Hum Genet. 61:1997;171-181.
    • (1997) Am J Hum Genet , vol.61 , pp. 171-181
    • Jarvik, G.P.1    Goode, E.L.2    Austin, M.A.3
  • 46
    • 0025816694 scopus 로고
    • Influences of common variants of apolipoprotein E on measures of lipid metabolism in a sample selected for health
    • Xhignesse M., Lussier-Cacan S., Sing C.F., Kessling A.M., Davignon J. Influences of common variants of apolipoprotein E on measures of lipid metabolism in a sample selected for health. Arterioscler Thromb. 11:1991;1100-1110.
    • (1991) Arterioscler Thromb , vol.11 , pp. 1100-1110
    • Xhignesse, M.1    Lussier-Cacan, S.2    Sing, C.F.3    Kessling, A.M.4    Davignon, J.5
  • 47
    • 0025815683 scopus 로고
    • Effects of polymorphisms in apolipoproteins E, A-IV, and H on quantitative traits related to risk for cardiovascular disease
    • Kaprio J., Ferrell R.E., Kottke B.A., Kamboh M.I., Sing C.F. Effects of polymorphisms in apolipoproteins E, A-IV, and H on quantitative traits related to risk for cardiovascular disease. Arterioscler Thromb. 11:1991;1330-1348.
    • (1991) Arterioscler Thromb , vol.11 , pp. 1330-1348
    • Kaprio, J.1    Ferrell, R.E.2    Kottke, B.A.3    Kamboh, M.I.4    Sing, C.F.5
  • 48
    • 0028243589 scopus 로고
    • Trends in acute myocardial infarction and coronary heart disease death in the United States
    • Gillum R.F. Trends in acute myocardial infarction and coronary heart disease death in the United States. J Am Coll Cardiol. 23:1994;1273-1277.
    • (1994) J Am Coll Cardiol , vol.23 , pp. 1273-1277
    • Gillum, R.F.1
  • 49
    • 0025944506 scopus 로고
    • Renin and atrial natriuretic peptide restriction fragment length polymorphisms: Association with ethnicity and blood pressure
    • Barley J., Carter N.D., Kennedy Cruickshank J., et al. Renin and atrial natriuretic peptide restriction fragment length polymorphisms association with ethnicity and blood pressure . J Hypertens. 9:1991;993-996.
    • (1991) J Hypertens , vol.9 , pp. 993-996
    • Barley, J.1    Carter, N.D.2    Kennedy Cruickshank, J.3
  • 50
    • 0345722168 scopus 로고
    • Relation of race and a polymorphism in the angiotensin I-converting enzyme gene to enzyme levels (abstract)
    • Bloem L.J., Manatunga A.K., Boatright E., et al. Relation of race and a polymorphism in the angiotensin I-converting enzyme gene to enzyme levels (abstract). Hypertension. 22:1993;407.
    • (1993) Hypertension , vol.22 , pp. 407
    • Bloem, L.J.1    Manatunga, A.K.2    Boatright, E.3
  • 51
    • 0344228457 scopus 로고
    • The role of the angiotensinogen gene in human hypertension: Absence of an association among African Americans (abstract)
    • Rotimi C.N., Cooper R.S., Ward R.H., et al. The role of the angiotensinogen gene in human hypertension absence of an association among African Americans (abstract) . Genet Epidemiol. 10:1993;339-340.
    • (1993) Genet Epidemiol , vol.10 , pp. 339-340
    • Rotimi, C.N.1    Cooper, R.S.2    Ward, R.H.3
  • 52
    • 0030027668 scopus 로고    scopus 로고
    • Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations
    • Jacques P.F., Bostom A.G., Williams R.R., et al. Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation. 93:1996;7-9.
    • (1996) Circulation , vol.93 , pp. 7-9
    • Jacques, P.F.1    Bostom, A.G.2    Williams, R.R.3
  • 53
    • 0028788020 scopus 로고
    • Total plasma homocysteine and cardiovascular risk profile. The Hordaland Homocysteine Study
    • Nygård O., Vollset S.E., Refsum H., et al. Total plasma homocysteine and cardiovascular risk profile. The Hordaland Homocysteine Study. JAMA. 274:1995;1526-1533.
    • (1995) JAMA , vol.274 , pp. 1526-1533
    • Nygård, O.1    Vollset, S.E.2    Refsum, H.3
  • 54
    • 0028600627 scopus 로고
    • Homocysteine and cysteine: Determinants of plasma levels in middle-aged and elderly subjects
    • Brattstrom L., Lindgren A., Israelsson B., Andersson A., Hultberg B. Homocysteine and cysteine determinants of plasma levels in middle-aged and elderly subjects . J Intern Med. 236:1994;633-641.
    • (1994) J Intern Med , vol.236 , pp. 633-641
    • Brattstrom, L.1    Lindgren, A.2    Israelsson, B.3    Andersson, A.4    Hultberg, B.5
  • 55
    • 1842331509 scopus 로고    scopus 로고
    • Plasma homocysteine as a risk factor for vascular disease: The European Concerted Action Project
    • Graham I.M., Daly L.E., Refsum H.M., et al. Plasma homocysteine as a risk factor for vascular disease the European Concerted Action Project . JAMA. 277:1997;1775-1781.
    • (1997) JAMA , vol.277 , pp. 1775-1781
    • Graham, I.M.1    Daly, L.E.2    Refsum, H.M.3
  • 57
    • 0030442977 scopus 로고    scopus 로고
    • Dietary intake pattern relates to plasma folate and homocysteine concentrations in the Framingham Heart Study
    • Tucker K.L., Selhub J., Wilson P.W., Rosenberg I.H. Dietary intake pattern relates to plasma folate and homocysteine concentrations in the Framingham Heart Study. J Nutr. 126:1996;3025-3031.
    • (1996) J Nutr , vol.126 , pp. 3025-3031
    • Tucker, K.L.1    Selhub, J.2    Wilson, P.W.3    Rosenberg, I.H.4
  • 58
    • 0032501990 scopus 로고    scopus 로고
    • Preventing coronary heart disease: B vitamins and homocysteine (Editorial)
    • Omenn G.S., Beresford S.A.A., Motulsky A.G. Preventing coronary heart disease B vitamins and homocysteine (Editorial) . Circulation. 97:1998;421-424.
    • (1998) Circulation , vol.97 , pp. 421-424
    • Omenn, G.S.1    Beresford, S.A.A.2    Motulsky, A.G.3
  • 59
    • 0027326358 scopus 로고
    • Clinical significance of genetic influences on cardiovascular drug metabolism
    • Arcavi L., Benowitz N.L. Clinical significance of genetic influences on cardiovascular drug metabolism. Cardiovasc Drugs Ther. 7:1993;311-324.
    • (1993) Cardiovasc Drugs Ther , vol.7 , pp. 311-324
    • Arcavi, L.1    Benowitz, N.L.2
  • 60
    • 9044254525 scopus 로고    scopus 로고
    • P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature
    • Nelson D.R., Koymans L., Kamataki T., et al. P450 superfamily update on new sequences, gene mapping, accession numbers and nomenclature . Pharmacogenetics. 6:1996;1-42.
    • (1996) Pharmacogenetics , vol.6 , pp. 1-42
    • Nelson, D.R.1    Koymans, L.2    Kamataki, T.3
  • 61
    • 0023854270 scopus 로고
    • Characterization of the common genetic defect in humans deficient in debrisoquine metabolism
    • Gonzalez F.J., Skoda R.C., Kimura S., et al. Characterization of the common genetic defect in humans deficient in debrisoquine metabolism. Nature. 331:1988;442-446.
    • (1988) Nature , vol.331 , pp. 442-446
    • Gonzalez, F.J.1    Skoda, R.C.2    Kimura, S.3
  • 62
    • 0028305240 scopus 로고
    • Identification of a new variant CYP2D6 allele with a single base deletion in exon 3 and its association with the poor metabolizer phenotype
    • Saxena R., Shaw G.L., Relling M.V., et al. Identification of a new variant CYP2D6 allele with a single base deletion in exon 3 and its association with the poor metabolizer phenotype. Hum Mol Genet. 3:1994;923-926.
    • (1994) Hum Mol Genet , vol.3 , pp. 923-926
    • Saxena, R.1    Shaw, G.L.2    Relling, M.V.3
  • 63
    • 0030432585 scopus 로고    scopus 로고
    • Frequent distribution of ultrarapid metabolizers of debrisoquine in an Ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles
    • Akullu E., Persson I., Bertilsson L., Johansson I., Rodrigues F., Ingelman-Sundberg M. Frequent distribution of ultrarapid metabolizers of debrisoquine in an Ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles. J Pharmacol Exp Ther. 278:1996;441-446.
    • (1996) J Pharmacol Exp Ther , vol.278 , pp. 441-446
    • Akullu, E.1    Persson, I.2    Bertilsson, L.3    Johansson, I.4    Rodrigues, F.5    Ingelman-Sundberg, M.6
  • 64
    • 0024534047 scopus 로고
    • Propranolol's metabolism is determined by both mephenytoin and debrisoquin hydroxylase activities
    • Ward S.A., Walle T., Walle U.K., Wilkinson G.R., Branch R.A. Propranolol's metabolism is determined by both mephenytoin and debrisoquin hydroxylase activities. Clin Pharmacol Ther. 45:1989;72-79.
    • (1989) Clin Pharmacol Ther , vol.45 , pp. 72-79
    • Ward, S.A.1    Walle, T.2    Walle, U.K.3    Wilkinson, G.R.4    Branch, R.A.5
  • 65
    • 0025305464 scopus 로고
    • The genetic polymorphism of debrisoquine/sparteine metabolism - clinical aspects
    • Eichelbaum M., Gross A.S. The genetic polymorphism of debrisoquine/sparteine metabolism - clinical aspects. Pharmacol Ther. 46:1990;377-394.
    • (1990) Pharmacol Ther , vol.46 , pp. 377-394
    • Eichelbaum, M.1    Gross, A.S.2
  • 66
    • 0027366792 scopus 로고
    • Individual variation in first-pass metabolism
    • Tam Y.K. Individual variation in first-pass metabolism. Clin Pharmacokinet. 25:1993;300-328.
    • (1993) Clin Pharmacokinet , vol.25 , pp. 300-328
    • Tam, Y.K.1
  • 67
    • 0029978949 scopus 로고    scopus 로고
    • Influence of diet and nutritional status on drug metabolism
    • Walter-Sack I., Klotz U. Influence of diet and nutritional status on drug metabolism. Clin Pharmacokinet. 31:1996;47-64.
    • (1996) Clin Pharmacokinet , vol.31 , pp. 47-64
    • Walter-Sack, I.1    Klotz, U.2
  • 68
    • 0027199749 scopus 로고
    • The response to lovastatin treatment in patients with heterozygous familial hypercholesterolemia is modulated by apolipoprotein E polymorphism
    • Carmena R., Roederer G., Mailloux H., Lussier-Cacan S., Davignon J. The response to lovastatin treatment in patients with heterozygous familial hypercholesterolemia is modulated by apolipoprotein E polymorphism. Metabolism. 42:1993;895-901.
    • (1993) Metabolism , vol.42 , pp. 895-901
    • Carmena, R.1    Roederer, G.2    Mailloux, H.3    Lussier-Cacan, S.4    Davignon, J.5
  • 69
    • 0028901424 scopus 로고
    • Effect of apolipoprotein E and A-IV phenotypes on the low density lipoprotein response to HMG CoA reductase inhibitor therapy
    • Ordovas J.M., Lopez-Miranda J., Perez-Jimenez F., et al. Effect of apolipoprotein E and A-IV phenotypes on the low density lipoprotein response to HMG CoA reductase inhibitor therapy. Atherosclerosis. 113:1995;157-166.
    • (1995) Atherosclerosis , vol.113 , pp. 157-166
    • Ordovas, J.M.1    Lopez-Miranda, J.2    Perez-Jimenez, F.3
  • 70
    • 0023186534 scopus 로고
    • Apolipoprotein E polymorphism and plasma cholesterol response to probucol
    • Nestruck A.C., Bouthillier D., Sing C.F., Davignon J. Apolipoprotein E polymorphism and plasma cholesterol response to probucol. Metabolism. 36:1987;743-747.
    • (1987) Metabolism , vol.36 , pp. 743-747
    • Nestruck, A.C.1    Bouthillier, D.2    Sing, C.F.3    Davignon, J.4
  • 71
    • 0025758615 scopus 로고
    • Ethnic differences in drug disposition and responsiveness
    • Wood A.J.J., Zhou H.H. Ethnic differences in drug disposition and responsiveness. Clin Pharmacokinet. 20:1991;350-373.
    • (1991) Clin Pharmacokinet , vol.20 , pp. 350-373
    • Wood, A.J.J.1    Zhou, H.H.2
  • 72
    • 0027276869 scopus 로고
    • Genetic basis for a lower prevalence of deficient CYP2D6 oxidative drug metabolism phenotypes in Black Americans
    • Evans W.E., Relling M.V., Rahman A., McLeod H.L., Scott E.P., Lin J.-S. Genetic basis for a lower prevalence of deficient CYP2D6 oxidative drug metabolism phenotypes in Black Americans. J Clin Invest. 91:1993;2150-2154.
    • (1993) J Clin Invest , vol.91 , pp. 2150-2154
    • Evans, W.E.1    Relling, M.V.2    Rahman, A.3    McLeod, H.L.4    Scott, E.P.5    Lin, J.-S.6
  • 75
    • 0030816341 scopus 로고    scopus 로고
    • Risk factors for atherosclerosis in young subjects: The PDAY study. Pathobiological Determinants of Atherosclerosis in Youth
    • Malcom G.T., Oalmann M.C., Strong J.P. Risk factors for atherosclerosis in young subjects: the PDAY study. Pathobiological Determinants of Atherosclerosis in Youth. Ann NY Acad Sci. 817:1997;179-188.
    • (1997) Ann NY Acad Sci , vol.817 , pp. 179-188
    • Malcom, G.T.1    Oalmann, M.C.2    Strong, J.P.3
  • 76
    • 0026530536 scopus 로고
    • The effects of nonpharmacologic interventions on blood pressure of persons with high normal levels. Results of the trials of hypertension prevention, phase I
    • The effects of nonpharmacologic interventions on blood pressure of persons with high normal levels. Results of the trials of hypertension prevention, phase I. JAMA. 267:1992;1213-1220.
    • (1992) JAMA , vol.267 , pp. 1213-1220
  • 77
    • 0028292602 scopus 로고
    • Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia
    • Grossman M., Raper S.E., Kozarsky K., et al. Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia. Nat Genet. 6:1994;335-341.
    • (1994) Nat Genet , vol.6 , pp. 335-341
    • Grossman, M.1    Raper, S.E.2    Kozarsky, K.3
  • 78
    • 0029958320 scopus 로고    scopus 로고
    • Gene transfer of naked DNA encoding for three isoforms of vascular endothelial growth factor stimulates collateral development in vivo
    • Takeshita S., Tsurumi Y., Couffinahl T., et al. Gene transfer of naked DNA encoding for three isoforms of vascular endothelial growth factor stimulates collateral development in vivo. Lab Invest. 75:1996;487-501.
    • (1996) Lab Invest , vol.75 , pp. 487-501
    • Takeshita, S.1    Tsurumi, Y.2    Couffinahl, T.3
  • 79
    • 0029133675 scopus 로고
    • Gene therapy for the vulnerable plaque
    • Feldman L.J., Isner J.M. Gene therapy for the vulnerable plaque. J Am Coll Cardiol. 26:1995;826-835.
    • (1995) J Am Coll Cardiol , vol.26 , pp. 826-835
    • Feldman, L.J.1    Isner, J.M.2
  • 80
    • 0030068024 scopus 로고    scopus 로고
    • Molecular genetics of human blood pressure variation
    • Lifton R.P. Molecular genetics of human blood pressure variation. Science. 272:1996;676-680.
    • (1996) Science , vol.272 , pp. 676-680
    • Lifton, R.P.1
  • 82
    • 0030866838 scopus 로고    scopus 로고
    • Predisposition genetic testing for late-onset disorders in adults. A position paper of the National Society of Genetic Counselors
    • McKinnon W.C., Baty B.J., Bennett R.L., et al. Predisposition genetic testing for late-onset disorders in adults. A position paper of the National Society of Genetic Counselors. JAMA. 278:1997;1217-1220.
    • (1997) JAMA , vol.278 , pp. 1217-1220
    • McKinnon, W.C.1    Baty, B.J.2    Bennett, R.L.3
  • 83
    • 0030852258 scopus 로고    scopus 로고
    • Ethical issues of genetic testing and their implications in epidemiologic studies
    • Bondy M., Mastromarino C. Ethical issues of genetic testing and their implications in epidemiologic studies. Ann Epidemiol. 7:1997;363-366.
    • (1997) Ann Epidemiol , vol.7 , pp. 363-366
    • Bondy, M.1    Mastromarino, C.2
  • 84
    • 0030021511 scopus 로고    scopus 로고
    • Pharmacoepidemiology: A scientific basis for outcomes research
    • Grasela T.H. Pharmacoepidemiology a scientific basis for outcomes research . Ann Pharmacother. 30:1996;188-190.
    • (1996) Ann Pharmacother , vol.30 , pp. 188-190
    • Grasela, T.H.1
  • 85
    • 0026573969 scopus 로고
    • Characteristics and prognostic implications of myosin missense mutations in familial hypertrophic cardiomyopathy
    • Watkins H., Rosenzweig A., Hwang D.S., et al. Characteristics and prognostic implications of myosin missense mutations in familial hypertrophic cardiomyopathy. N Engl J Med. 326:1992;1108-1114.
    • (1992) N Engl J Med , vol.326 , pp. 1108-1114
    • Watkins, H.1    Rosenzweig, A.2    Hwang, D.S.3
  • 86
    • 0028178083 scopus 로고
    • Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: A disease of the sarcomere
    • Thierfelder L., Watkins H., MacRae C., et al. Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy a disease of the sarcomere . Cell. 77:1994;701-712.
    • (1994) Cell , vol.77 , pp. 701-712
    • Thierfelder, L.1    Watkins, H.2    MacRae, C.3
  • 87
    • 0028844204 scopus 로고
    • Mutations in the cardiac myosin binding protein-C gene on chromosome 11 cause familial hypertrophic cardiomyopathy
    • Watkins H., Conner D., Thierfelder L., et al. Mutations in the cardiac myosin binding protein-C gene on chromosome 11 cause familial hypertrophic cardiomyopathy. Nat Genet. 11:1995;434-437.
    • (1995) Nat Genet , vol.11 , pp. 434-437
    • Watkins, H.1    Conner, D.2    Thierfelder, L.3


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