메뉴 건너뛰기




Volumn 66, Issue 2, 1999, Pages 123-129

Korean red ginseng saponins with low ratios of protopanaxadiol and protopanaxatriol saponin improve scopolamine-induced learning disability and spatial working memory in mice

Author keywords

Korean red ginseng saponin; Memory; PD PT ratio; Scopolamine

Indexed keywords

GINSENOSIDE RB 1; GINSENOSIDE RB 2; GINSENOSIDE RC; GINSENOSIDE RD; GINSENOSIDE RE; GINSENOSIDE RG 1; GINSENOSIDE RG 2; PROTOPANAXADIOL; PROTOPANAXATRIOL; SAPONIN; SCOPOLAMINE; UNCLASSIFIED DRUG;

EID: 0032985664     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-8741(98)00190-1     Document Type: Article
Times cited : (79)

References (20)
  • 1
    • 0019972810 scopus 로고
    • The cholinergic hypothesis of geriatric memory dysfunction
    • Bartus R.T., Dean R.L., Beer B., Lippa A.S. The cholinergic hypothesis of geriatric memory dysfunction. Science. 217:1982;408-417.
    • (1982) Science , vol.217 , pp. 408-417
    • Bartus, R.T.1    Dean, R.L.2    Beer, B.3    Lippa, A.S.4
  • 2
    • 0022636674 scopus 로고
    • Patterns of memory failure after scopolamine treatment: Implications for cholinergic hypotheses of dementia
    • Beatty W.W., Buttlers N., Janowsky D.S. Patterns of memory failure after scopolamine treatment: implications for cholinergic hypotheses of dementia. Behavioral and Neural Biology. 45:1986;196-211.
    • (1986) Behavioral and Neural Biology , vol.45 , pp. 196-211
    • Beatty, W.W.1    Buttlers, N.2    Janowsky, D.S.3
  • 3
    • 0026615912 scopus 로고
    • Actions of ginsenoside Rb1 on choline uptake in central cholinergic nerve endings
    • Benishin C.G. Actions of ginsenoside Rb1 on choline uptake in central cholinergic nerve endings. Neurochemistry International. 21:1992;1-5.
    • (1992) Neurochemistry International , vol.21 , pp. 1-5
    • Benishin, C.G.1
  • 4
    • 0025921617 scopus 로고
    • Effects of ginsenoside Rb1 on central cholinergic metabolism
    • Benishin C.G., Lee R., Wang L.C.H., Liu H.J. Effects of ginsenoside Rb1 on central cholinergic metabolism. Pharmacology. 42:1991;223-229.
    • (1991) Pharmacology , vol.42 , pp. 223-229
    • Benishin, C.G.1    Lee, R.2    Wang, L.C.H.3    Liu, H.J.4
  • 6
  • 8
    • 0026572088 scopus 로고
    • Extract yields and saponin contents of red ginseng extracts prepared with various concentrations of ethanol
    • Ko S.-R., Kim S.-C., Choi K.-J. Extract yields and saponin contents of red ginseng extracts prepared with various concentrations of ethanol. Korean Journal of Pharmacognosy. 23:1992;24-30.
    • (1992) Korean Journal of Pharmacognosy. , vol.23 , pp. 24-30
    • Ko, S.-R.1    Kim, S.-C.2    Choi, K.-J.3
  • 9
    • 0023080349 scopus 로고
    • Effect of piracetam and of standardized ginseng extract on the electroconvulsive shock-induced memory disturbances in step-down passive avoidance
    • Lasarova M.B., Mosharrof A.H., Petkov V.D., Markovska V.L., Petkov V.V. Effect of piracetam and of standardized ginseng extract on the electroconvulsive shock-induced memory disturbances in step-down passive avoidance. Acta Physiologica et Pharmacologica Bulgarica. 13:1987;11-17.
    • (1987) Acta Physiologica et Pharmacologica Bulgarica , vol.13 , pp. 11-17
    • Lasarova, M.B.1    Mosharrof, A.H.2    Petkov, V.D.3    Markovska, V.L.4    Petkov, V.V.5
  • 10
    • 0027422516 scopus 로고
    • Effect of 20(S)-ginsenoside-Rg2 and cyprohepadine on two-way active avoidance learning and memory in rats
    • Ma T.C., Yu Q.H. Effect of 20(S)-ginsenoside-Rg2 and cyprohepadine on two-way active avoidance learning and memory in rats. Drug Research. 43:1993;1049-1052.
    • (1993) Drug Research , vol.43 , pp. 1049-1052
    • Ma, T.C.1    Yu, Q.H.2
  • 11
    • 0018858665 scopus 로고
    • Failure of piracetam to facilitate acquisition or retention in younger or older rats
    • Means L.W., Franklin R.D., Cliett C.E. Failure of piracetam to facilitate acquisition or retention in younger or older rats. Experimental Aging Research. 6:1980;175-180.
    • (1980) Experimental Aging Research , vol.6 , pp. 175-180
    • Means, L.W.1    Franklin, R.D.2    Cliett, C.E.3
  • 12
    • 0024455878 scopus 로고
    • Synaptic plasticity and learning: Selective impairment of learning in rats and blockade of long-term potentiation in vivo by the N-methyl-D-aspartate receptor antagonist AP5
    • Morris R.G.M. Synaptic plasticity and learning: Selective impairment of learning in rats and blockade of long-term potentiation in vivo by the N-methyl-D-aspartate receptor antagonist AP5. Journal of Neuroscience. 9:1989;3040-3057.
    • (1989) Journal of Neuroscience , vol.9 , pp. 3040-3057
    • Morris, R.G.M.1
  • 13
    • 0028825740 scopus 로고
    • Panax ginseng extract improves the scopolamine-induced disruption of 8-arm radial maze performance in rats
    • Nitta H., Matsumoto K., Shimizu M., Ni X.-H., Watanabe H. Panax ginseng extract improves the scopolamine-induced disruption of 8-arm radial maze performance in rats. Biological and Pharmaceutical Bulletin. 18:1995;1439-1442.
    • (1995) Biological and Pharmaceutical Bulletin , vol.18 , pp. 1439-1442
    • Nitta, H.1    Matsumoto, K.2    Shimizu, M.3    Ni, X.-H.4    Watanabe, H.5
  • 15
    • 0023065860 scopus 로고
    • Effects of standardized ginseng extract on learning, memory and physical capabilities
    • Petkov V.D., Mosharrof A.H. Effects of standardized ginseng extract on learning, memory and physical capabilities. American Journal of Chinese Medicine. 15:1987;19-29.
    • (1987) American Journal of Chinese Medicine , vol.15 , pp. 19-29
    • Petkov, V.D.1    Mosharrof, A.H.2
  • 16
    • 0027410729 scopus 로고
    • Memory effects of standardized extracts of Panaxa ginseng (G115), Ginkgo biloba (GK 501) and their combination Gincosan (PHL-00701)
    • Petkov V.D., Kehayov R., Belcheva S. et al. Memory effects of standardized extracts of Panaxa ginseng (G115), Ginkgo biloba (GK 501) and their combination Gincosan (PHL-00701). Planta Medica. 59:1993;106-114.
    • (1993) Planta Medica , vol.59 , pp. 106-114
    • Petkov, V.D.1    Kehayov, R.2    Belcheva, S.3
  • 17
  • 18
    • 0028803581 scopus 로고
    • Effects of ginsenosides on impaired performance induced in the rat by scopolamine in a radial-arm maze
    • Yamaguchi Y., Haruta K., Kobayashi H. Effects of ginsenosides on impaired performance induced in the rat by scopolamine in a radial-arm maze. Psychoneuroendocrinology. 20:1995;645-653.
    • (1995) Psychoneuroendocrinology , vol.20 , pp. 645-653
    • Yamaguchi, Y.1    Haruta, K.2    Kobayashi, H.3
  • 19
    • 0030603236 scopus 로고    scopus 로고
    • Effects of ginsenosides on impaired performance caused by scopolamine in rats
    • Yamaguchi Y., Higashi M., Kobayashi H. Effects of ginsenosides on impaired performance caused by scopolamine in rats. European Journal of Pharmacology. 312:1996;149-151.
    • (1996) European Journal of Pharmacology , vol.312 , pp. 149-151
    • Yamaguchi, Y.1    Higashi, M.2    Kobayashi, H.3
  • 20
    • 0028312019 scopus 로고
    • Study on the nootropic mechanism of ginsenoside Rb1 and Rg1: Influence on mouse brain development
    • Ying Y., Zhang J.T., Shi C.Z., Qu Z.W., Liu Y. Study on the nootropic mechanism of ginsenoside Rb1 and Rg1: influence on mouse brain development. Yao Hsueh Hsueh Pao. 29:1994;241-245.
    • (1994) Yao Hsueh Hsueh Pao , vol.29 , pp. 241-245
    • Ying, Y.1    Zhang, J.T.2    Shi, C.Z.3    Qu, Z.W.4    Liu, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.