Interaction of human serum albumin with furosemide glucuronide: A role of albumin in isomerization, hydrolysis, reversible binding and irreversible binding of a 1-O-acyl glucuronide metabolite

Biopharmaceutics and Drug Disposition

Volumn 20, Issue 3, 1999, Pages 131-136

  Mizuma, Takashi ^a,b   Benet, Leslie Z ^a   Lin, Emil T ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

1 O acyl glucuronide; Acyl migration; Albumin; Hydrolysis; Irreversible binding; Reversible binding

Indexed keywords

FUROSEMIDE; GLUCURONIDE; HUMAN SERUM ALBUMIN; WARFARIN;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG HYDROLYSIS; DRUG PROTEIN BINDING; ISOMERISM;

ACYLATION; BINDING SITES; FUROSEMIDE; HUMANS; HYDROLYSIS; SERUM ALBUMIN; STEREOISOMERISM;

EID: 0032985024     PISSN: 01422782     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-081X(199904)20:3<131::AID-BDD166>3.0.CO;2-X     Document Type: Article

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