Antiinflammatory activity and acute toxicity (LD50) of the juice of Kalanchoe brasiliensis (Comb.) leaves picked before and during blooming

Phytotherapy Research

Volumn 13, Issue 4, 1999, Pages 352-354

  Mourao R H V ^a   Santos, F O ^a   Franzotti, E M ^a   Moreno, M P N ^a   Antoniolli, A R ^a  

^a FEDERAL UNIVERSITY OF SERGIPE   (Brazil)

Author keywords

Acute toxicity; Antiinflammatory activity; Carrageenin; Kalanchoe brasiliensis

Indexed keywords

CARRAGEENAN; KALANCHOE BRASILIENSIS EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; FEMALE; INTRAPERITONEAL DRUG ADMINISTRATION; LD 50; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PAW EDEMA; PLANT LEAF; RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; FEMALE; INDOMETHACIN; LETHAL DOSE 50; MALE; MICE; PLANTS, MEDICINAL; RATS; RATS, WISTAR;

ANIMALIA; KALANCHOE; KALANCHOE INTEGRA VEREA;

EID: 0032984980     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1573(199906)13:4<352::AID-PTR452>3.0.CO;2-T     Document Type: Article

References (9)

1. Correa Júnior, C., Ming, L. C., and Scheffer, M. C. (1991). Cultivo de Plantas Medicinais, Condimentares e Aromáticas, p. 151 Emater-Paraná, PR.
2. Da Silva, S. A., Costa, S. S., Mendonca, S. C., Silva, E. M., Moraes, V. L. and Rossi Bergmann, B. (1995). Therapeutic effect of oral Kalanchoe pinnata leaf extract in murine leishmaniasis. Acta Trop. 60, 201-210.
3. Danilov, L. N. (1979). Kalanchoe juice in the treatment of cheilitis and chapped lips in children. Stomatologija 58, 75.
4. Di Rosa, M. (1974). Effect of non-steroidal anti-inflammatory drugs on leucocyte migration. In Future Trends in Inflammation, ed. by G. P. Velo and D. A. Willoughby, pp. 143-152. Piccin Medical Books, Padova.
5. Dietrich, L. (1983). A new approach to practical acute toxicity testing. L. Arch. Toxicol. 54, 275-287.
6. Kurchinskii, I. N., and Sharaevskaia, Z. N. (1971). Kalanchoe juice in the local treatment of periodontal disease. Stomatologija, 65, 105-106.
7. Vinger, R., Truax, J. F., Selph, J. L., Johnston, P. R., Venable, A. L. and McKenzie, K. K. (1987). Pathway to carrageenan-induced inflammation in the hind limb of the rat. Fed. Proc. 46, 118-126.
8. Williams, M. C., and Smith, M. C. (1984). Toxicity of Kalanchoe spp to chicks. Am J. Vet Res. 45, 543-546.
9. Winter, C. A., Risley, E. A. and Nuss, G. W. (1962). Carrageenin-induced oedema in hind paw of the rat as an assay for anti-inflammatory drugs. Proc. Soc. Exp. Biol. Med. 111, 544-547.