Blockade by N-3 polyunsaturated fatty acid of the Kv4.3 current stably expressed in Chinese hamster ovary cells

British Journal of Pharmacology

Volumn 127, Issue 4, 1999, Pages 941-948

  Singleton, C B ^a   Valenzuela, S M ^b   Walker, B D ^a   Tie, H ^a   Wyse, K R ^a   Bursill, J A ^a   Qiu, M R ^b   Breit, S N ^b   Campbell, T J ^a,b  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b ST VINCENT S HOSPITAL   (Australia)

Author keywords

Arrhythmia; Fatty acid; Kv4.3; Potassium current; Transient outward current

Indexed keywords

DOCOSAHEXAENOIC ACID; POLYUNSATURATED FATTY ACID;

ANIMAL CELL; ARTICLE; CHO CELL; GENETIC TRANSFECTION; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL;

ANIMALS; CHO CELLS; CRICETINAE; DOCOSAHEXAENOIC ACIDS; FATTY ACIDS, OMEGA-3; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; RECOMBINANT PROTEINS; SHAL POTASSIUM CHANNELS; TEMPERATURE; TIME FACTORS;

EID: 0032984631     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702638     Document Type: Article

References (30)

1. ALBERT, C.M., HENNEKENS, C.H., O'DONNELL, C.J., AJANI, U.A., CAREY, V.J., WILLETT, W.C., RUSKIN, J.N. & MANSON, J.E. (1998). Fish consumption and risk of sudden cardiac death. J. Am. Med. Assoc., 279, 23-28.
2. ANTZELEVITCH, C., SICOURI, S., LITOVSKY, S.H. & LUKAS, A. (1991). Heterogeneity within the ventricular wall. Electrophysiology and pharmacology of epicardial, endocardial, and M cells. Circ. Res., 69, 1427-1449.
3. ASCHERIO, A., RIMM, E.B., STAMPFER, M.J., GIOVANNUCCI, E.L. & WILLETT, W.C. (1995). Dietary intake of marine n-3 fatty acids, fish intake, and the risk of coronary disease among men. N. Engl. J. Med., 332, 977-982.
4. BANG, H.O., DYERBERG, J. & HORNE, N. (1976). The composition of food consumed by Greenland Eskimos. Acta. Med. Scand., 200, 69-73.
5. BARRY, D.M., XU, H., SCHUESSLER, R.B. & NERBONNE, J.M. (1998). Functional knockout of the transient outward current, long-QT syndrome and cardiac remodelling in mice expressing a dominant-negative Kv4 alpha subunit. Circ. Res., 83, 560-567.
6. BARRY, P.H. (1994). JPCalc, a software package for calculating liquid junction potential corrections in patch-clamp, intracellular, epithelial and bilayer measurements and for correcting junction potential measurements. J. Neurosci. Methods, 51, 107-116.
7. BILLMAN, G.E., HALLAQ, H. & LEAF, A. (1994). Prevention of ischemia-induced ventricular fibrillation by omega 3 fatty acids. Proc. Natl. Acad. Sci. U.S.A., 91, 4427-4430.
8. BOGDANOV, K.Y., SPURGEON, H.A., VINOGRADOVA, T.M. & LAKATTA, E.G. (1998). Modulation of the transient outward current in adult rat ventricular myocytes by polyunsaturated fatty acids. Am. J. Physiol., 274, H571-H579.
9. BURR, M.L., GILBERT, J.F., HOLLIDAY, R.M., ELWOOD, P.C., FEHILY, A.M., ROGERS, S., SWEETNAM, P.M. & DEADMAN, N.M. (1989). Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: Diet and reinfarction trial. Lancet, 8666, 757-761.
10. CAMPBELL, D.L., RASMUSSON, R.L., COMER, M.B. & STRAUSS, H.C. (1995). The cardiac calcium independent transient outward potassium: kinetics, molecular properties and role in ventricular repolarisation. In Cardiac electrophysiology: from cell to bedside. (Second Edition) ed. Zipes, D.P. Jalife, J. pp 83-96. Philadelphia, PA: Saunders and Co. Ltd.
11. DIXON, J.E., SHI, W., MCDONALD, C., YU, H., WYMORE, R.S., COHEN, I.S. & MCKINNON, D. (1996). Role of the Kv4.3 K + channel in Ventricular Muscle. A molecular correlate for the Transient Outward Current. Circ. Res., 79, 659-668.
12. ECHT, D.S., LIEBSON, P.R., MITCHELL, B., PETERS, R.W., OBIAS-MANNO, D., BARKER, A.H., ARENSBERG, D., BAKER, A., FRIEDMAN, L., GREENE, H.L., HURTHER, M.L., RICHARDSON, D.W. & THE CAST INVESTIGATORS. (1991). Mortality and morbidity in patients receiving encainide, flecainide, or placebo: the Cardiac Arrhythmia Suppression Trial. N. Engl. J. Med., 324, 781-788.
13. ESCANDE, D., COULOMBE, A., FAIVRE, J.-F., DEROUBAIX, E. & CORABOEUF, E. (1987). Two types of transient outward currents in adult human atrial cells. Am. J. Physiol., 252, H142-H148.
14. FAIVRE, J.-F., CALMELS, T., ROUANET, S., JAVRE, J.-L., CHEVAL, B. & BRIL, A. (1999). Characterisatiaon of Kv4.3 in HEK293 cells: comparison with the rat ventricular transient outward potassium current. Cardiovascular Res., 41, 188-199.
15. GISSI INVESTIGATORS. (1993). Protocollo dello studio GISSI-Prevenzione. Studio di intervento sulle componenti atersclerotica e trombotica del rischio post-infarcto. G. Ital. Cardiol., 23, 1053-1061.
16. HALLAQ, H., SMITH, T.W. & LEAF, A. (1992). Modulation of dihydropyridine-sensitive calcium channels in heart cells by fish oil fatty acids. Proc. Natl. Acad. Sci. U.S.A., 89, 1760-1764.
17. JACOBS, A.K., WEINER, B.H., RAIZNER, A., SCHOENFELD, D.A., SCHEER, J., MAHRER, P., COTE, G., SLACK, J., KELLETT, M.A., JORGENSEN, M. & LEAF, A. (1994). The impact of fish oil on restenosis following coronary angioplasty: the fish oil restonosis trial (FORT) [abstract]. J. Am. Coll. Cardiol., 23, 59A.
18. KROMHOUTT, D., BOSSCHIETER, E.B. & COULANDER, C. (1985). The inverse relation between fish consumption and 20-year mortality from coronary artery disease. N. Engl. J. Med., 312, 1205-1209.
19. LEAF, A., JORGENSEN, M.B., JACOBS, A.K., COTE, G., SCHOENFELD, D.A., SCHEER, J., WEINER, B.H., SLACK, J.D., KELLETT, M.A., RAIZNER, A.E., WEBER, P.C., MAHRER, P.R. & ROSSOUW, J.E. (1994). Do fish oils prevent restonosis after coronary angioplasty? Circulation, 90, 2248-2257.
20. LEAF, A. & WEBER, P.C. (1988). Cardiovascular effects of n-3 fatty acids. N. Engl. J. Med., 318, 549-557.
21. LUKAS, A. & ANTZELEVITCH, C. (1993). Differences in the electrophysiological response of canine ventricular epicardium and endocardium to ischaemia. Role of the transient outward current. Circulation, 88, 2903-2915.
22. MCLENNAN, P.L., ABEYWARDENA, M.Y. & CHARNOCK, J.S. (1988). Dietary fish oil prevents ventricular fibrillation following coronary artery occlusion and reperfusion. Am. Heart J., 116, 709-717.
23. MCLENNAN, P.L., BRIDLE, T.M., ABEYWARDENA, M.Y. & CHARNOCK, J.S. (1992). Dietary lipid modulation of ventricular fibrillation threshold in the marmoset monkey. Am. Heart J., 123, 1555-1561.
24. NABAUER, M., BEUCKELMANN, D.J. & ERDMANN, E. (1993). Characteristics of transient outward current in human ventricular myocytes from patients with terminal heart failure. Circ. Res., 73, 386-394.
25. PEPE, S., BOGDANOV, K., HALLAQ, H., SPURGEON, H., LEAF, A. & LAKATTA, E. (1994). ω3 polyunsaturated fatty acid modulates dihydropyridine effects on L-type Ca2+ channels, cytosolic Ca2+, and contraction in adult rat cardiac myocytes. Proc. Natl. Acad. Sci. U.S.A., 91, 8832-8836.
26. 10 in determining action potential duration in rabbit ventricular myocytes. Circulation, 98, 1-126.
27. SISCOVICK, D.S., RAGHUNATHAN, T.E., KING, I., WEINMANN, S., WICKLUND, K.G., ALBRIGHT, J., ARBOGAST, P., SMITH, H., KUSHI, L.H., COBB, L.A., COPASS, M.K., PSATY, B.M., LEMAITRE, R., RETZLAFF, B., CHILDS, M. & KNOPP, R.H. (1995). Dietary intake and cell membrane levels of long-chain n-3 polyunsaturated fatty acids and the risk of primary cardiac arrest. J. Am. Med. Assoc., 274, 1363-1367.
28. TSENG, G.-N. & HOFFMAN, B.F. (1989). Two components of transient outward current in canine ventricular myocytes. Circ. Res., 64, 633-647.
29. WANG, H., DIXON, J.E., MCKINNON, D. (1997). Unexpected and differential effects of Cl(channel blockers on the Kv4.3 and Kv4.2 K+ channels. Implications for the study of the Ito2 current. Circ. Res., 81, 711-718.
30. XIAO, Y., KANG, J.X., MORGAN, J.P. & LEAF, A. (1995). Blocking effects of polyunsaturated fatty acids on Na+ channels of neonatal rat ventricular myocytes. Proc. Natl. Acad. Sci. U.S.A., 92, 11000-11004.