Evaluation of ofloxacin in the treatment of laparoscopically documented acute pelvic inflammatory disease (salpingitis)

Infectious Diseases in Obstetrics and Gynecology

Volumn 7, Issue 3, 1999, Pages 138-144

  Peipert, J F ^a   Sweet, R L ^b   Walker, C K ^c   Kahn, J ^d   Rielly Gauvin, K ^d  

^a RHODE ISLAND HOSPITAL   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Ortho McNeil Pharmaceutical Incorporated   (United States)

Author keywords

Adnexitis; Chlamydia trachomatis; Fluoroquinolone; Neisseria gonorrhoeae; Salpingitis; Sexually transmitted disease

Indexed keywords

OFLOXACIN;

ADNEXITIS; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC THERAPY; ARTICLE; CHLAMYDIA TRACHOMATIS; DOSE RESPONSE; DRUG DETERMINATION; DRUG EFFICACY; FEMALE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LAPAROSCOPY; MAJOR CLINICAL STUDY; NAUSEA; NEISSERIA GONORRHOEAE; NEUROTOXICITY; PRIORITY JOURNAL; SALPINGITIS;

ADMINISTRATION, ORAL; ADULT; ANTI-INFECTIVE AGENTS; CHLAMYDIA INFECTIONS; CHLAMYDIA TRACHOMATIS; DRUG ADMINISTRATION SCHEDULE; FEMALE; GONORRHEA; HUMANS; INJECTIONS, INTRAVENOUS; LAPAROSCOPY; MICROBIAL SENSITIVITY TESTS; NEISSERIA GONORRHOEAE; OFLOXACIN; SALPINGITIS; TREATMENT OUTCOME; UNITED STATES;

EID: 0032984519     PISSN: 10647449     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-0997(1999)7:3<138::AID-IDOG5>3.0.CO;2-9     Document Type: Article

References (18)

1. Sweet RL, Gibbs RS. Pelvic inflammatory disease. In: Infectious Diseases of the Female Genital Tract. 3rd ed. Baltimore, MD: Williams & Wilkins, 1995. p 378-428.
2. Eschenbach DA, Buchanan TM, Pollock HM, et al. Polymicrobial etiology of acute pelvic inflammatory disease. N Engl J Med 1975;293:166-171.
3. Toomey KE, Rafferty MP, Stamm WE. Unrecognized high prevalence of Chlamydia trachomatis cervical infection in an isolated Alaskan Eskimo population. JAMA 1987;258:53-56.
4. Schachter J, Stoner E, Moncada J. Screening for chlamydial infections in women attending family planning clinics. Evaluation of presumptive indicators for therapy. West J Med 1983;138:375-379.
5. Jossens MOR, Schachter J, Sweet RL. Risk factors associated with pelvic inflammatory disease of differing antimicrobial etiologies. Obstet Gynecol 1994;83:989-997.
6. Centers for Disease Control and Prevention: Pelvic inflammatory disease. In: 1998 Guidelines for the Treatment of Sexually Transmitted Diseases. MMWR 1998;47(RR-1):79-85.
7. Monk JP, Campoli-Richards DM. Ofloxacin: review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs 1987;33:346-391.
8. Soper DE, Brockwell NJ, Dalton HP. Microbial etiology of urban emergency department with acute salpingitis: treatment with ofloxacin. Am J Obstet Gynecol 1992; 167:653-660.
9. McCormack WM, Nowroozi K, Alpert S, et al. Acute pelvic inflammatory disease: characteristics of patients with gonococcal and nongonococcal infection and evaluation of their response to treatment with aqueous procaine penicillin G and spectinomycin hydrochloride. Sex Transm Dis 1977;4:125-131.
10. Peipert JF, Boardman LA, Sung CJ. Performance of clinical and laparoscopic criteria for the diagnosis of upper genital tract infection. Infect Dis Obstet 1998;5: 291-296.
11. Performance Standards for Antimicrobial Disk Susceptibility Tests. 5th ed. Approved Standard 1993. National Committee for Clinical Laboratory Standards 13(24) (order code M2-A5).
12. Methods for Dilution Antimicrobial Susceptibility Test for Bacteria That Grow Aerobically. 3rd ed. Approved Standard 1993. National Committee for Clinical Laboratory Standards, 13(25) (order code M7-A3).
13. Alternative Methods for Antimicrobial Susceptibility Testing of Anaerobic Bacteria. 3rd ed. Approved Standard 1993. National Committee for Clinical Laboratory Standards 13(26) (order code M11-A3).
14. Fleiss J (ed). Statistical Methods for Rates and Proportions. 2nd ed. New York: John Wiley & Sons Inc, 1981.
15. SAS (Statistical Analysis System): User's Guide, Statistics. 5th ed. Cary, NC: SAS Institute, 1985.
16. Martens MG, Gordon S, Yarborough DR, Faro S, Binder D, Berkeley A. Multicenter randomized trial of ofloxacin versus cefoxitin and doxycycline in outpatient treatment of pelvic inflammatory disease. South Med 1993; 86:604-610.
17. Wendel GD, Cox SM, Bawdon RE, Theriot SK, Heard MC, Nobles BJ. A randomized trial of ofloxacin versus cefoxitin and doxycycline in the outpatient treatment of acute salpingitis. Am J Obstet Gynecol 1991;164:1390-1396.
18. Sweet RL, Schachter J, Robbie MO. Failure of betalactam antibiotics to eradicate Chlamydia trachomatis in the endometrium despite apparent clinical cure of acute salpingitis. JAMA 1983;250:2641-2645.