The matrix delivers

Nature Medicine

Volumn 5, Issue 7, 1999, Pages 733-734

  Lauffenburger, D A ^a   Schaffer, D V ^b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE REGENERATION; GENE TARGETING; GENE THERAPY; GENETIC ENGINEERING; HUMAN; PRIORITY JOURNAL; SHORT SURVEY; TISSUE REGENERATION;

ANIMALS; BIOCOMPATIBLE MATERIALS; BONE REGENERATION; EXTRACELLULAR MATRIX; GENE THERAPY; HUMANS; OSTEOBLASTS; OSTEOCLASTS; PARATHYROID HORMONE; PROTEIN BIOSYNTHESIS; RECOMBINANT PROTEINS; TRANSCRIPTION, GENETIC;

EID: 0032984495     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/10451     Document Type: Short Survey

References (9)

1. Bonadio, J., E. Smiley, P. Patil, & Goldstein, S. Localized, direct plasmid gene delivery in vivo: prolonged therapy results in reproducible tissue regeneration. Nature Med. 5, 753-759 (1999).
2. Shea, L.D., Smiley, E., Bonadio, J. & Mooney, D.J. DNA delivery from polymer matrices for tissue engineering. Nature Biotechnol. 17, 551-554 (1999).
3. Barr, E. & Leiden, J. Systemic delivery of recombinant proteins by genetically modified myoblasts. Science 254, 1507-1512 (1991).
4. Langer, R. & Vacanti, J.P. Tissue engineering. Science 260, 920-926 (1993).
5. Eming, S.A., M.L. Yarmush, & Morgan, J.R. Enhanced function of cultured epithelium by genetic modification: cell-based synthesis and delivery of growth factors. Biotechnol. Bioeng. 52, 15-23 (1996).
6. Legendre, J.-Y. & Szoka, F.C.Jr. Delivery of plasmid DNA into mammalian cell lines using pH-sensitive liposomes: comparison with cationic liposomes. Pharmacol. Res. 9, 1235-1242 (1992).
7. Petersen, M.J. et al. Sustained production of human transferrin by transduced fibroblasts implanted into athymic mice: a model for somatic gene therapy. J. Invest. Dermatol. 104, 171-176 (1995).
8. Truong-Le, V.L., August, J.T. & Leong, K.W. Controlled gene delivery by DNA-gelatin nanospheres. Hum. Gene Ther. 9, 1709-1717 (1998).
9. Schaffer, D.V. & Lauffenburger, D.A. (1998). Optimization of cell surface binding enhances efficiency and specificity of molecular conjugate gene delivery. J. Biol. Chem. 273, 28004-28009 (1998).