Neuronal nitric oxide synthase inhibition reduces MPP+-evoked hydroxyl radical formation but not dopamine efflux in rat striatum

Journal of Neural Transmission

Volumn 106, Issue 5-6, 1999, Pages 477-486

  Rose, S ^a   Hindmarsh, J G ^a   Jenner, P ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Dopamine; Microdialysis; MPP+; Nitric oxide synthase; Salicylic acid trapping; Striatum

Indexed keywords

1 METHYL 4 PYRIDINIUM; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 2,3 DIHYDROXYBENZOIC ACID; 3,4 DIHYDROXYPHENYLACETIC ACID; 7 NITROINDAZOLE; DOPAMINE; HYDROXYL RADICAL; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NOMIFENSINE; PYRIDINIUM DERIVATIVE; SALICYLIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CELL; CELL DEGENERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE RELEASE; HYDROXYLATION; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; SUBSTANTIA NIGRA;

1-METHYL-4-PHENYLPYRIDINIUM; 3,4-DIHYDROXYPHENYLACETIC ACID; ANALYSIS OF VARIANCE; ANIMALS; CORPUS STRIATUM; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HYDROXYBENZOIC ACIDS; HYDROXYL RADICAL; INDAZOLES; MALE; MICRODIALYSIS; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; RATS; RATS, WISTAR;

EID: 0032984455     PISSN: 03009564     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007020050172     Document Type: Article

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