The vigilance promoting drug modafinil increases extracellular glutamate levels in the medial preoptic area and the posterior hypothalamus of the conscious rat prevention by local GABA(A) receptor blockade

Neuropsychopharmacology

Volumn 20, Issue 4, 1999, Pages 346-356

  Ferraro, Luca ^a   Antonelli, Tiziana ^a   Tanganelli, Sergio ^a   O'Connor, William T ^b   De La Mora, Miguel Perez ^c   Mendez Franco, Jesus ^c   Rambert, Francis A ^d   Fuxe, Kjell ^e  

^a UNIVERSITY OF FERRARA   (Italy)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^d Neuropsychopharmacologie   (France)

^e KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Extracellular glutamate levels; GABA(A) agonist; GABA(A) antagonist; Medial preoptic area; Posterior hypothalamus; Vigilance

Indexed keywords

2,4 PYRROLIDINEDICARBOXYLIC ACID; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; BICUCULLINE; GLUTAMIC ACID; MODAFINIL; MUSCIMOL; NEUROTRANSMITTER UPTAKE INHIBITOR;

ALERTNESS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GABAERGIC TRANSMISSION; HYPOTHALAMUS; IN VITRO STUDY; MALE; NEUROTRANSMISSION; NEUROTRANSMITTER UPTAKE; NONHUMAN; PREOPTIC AREA; PRIORITY JOURNAL; RAT; REGIONAL PERFUSION; SLEEP WAKING CYCLE;

AMINO ACIDS; ANIMALS; AROUSAL; BENZHYDRYL COMPOUNDS; CENTRAL NERVOUS SYSTEM STIMULANTS; EXTRACELLULAR SPACE; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; HYPOTHALAMUS, POSTERIOR; MALE; MICRODIALYSIS; PREOPTIC AREA; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; STIMULATION, CHEMICAL;

EID: 0032983834     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(98)00085-2     Document Type: Article

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