Effect of cytokines on production of insulin-like growth factor binding proteins (IGFBPs) from human fibroblasts in culture

Endocrine Journal

Volumn 46, Issue SUPPL., 1999, Pages

  Liu, Yanjung ^a,b   Tsushima, Toshio ^a   Miyakawa, Megumi ^a   Isozaki, Osamu ^b   Yamada, Hitomi ^a   Xu, Zhang Rong ^b   Iwamoto, Yasuhiko ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^b Department of Endocrinology   (China)

Author keywords

IGFBP; IL 1 ; TNF

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 1BETA; INTERLEUKIN 6; SOMATOMEDIN BINDING PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

BINDING AFFINITY; CATABOLISM; CELL CULTURE; CONFERENCE PAPER; ENZYME ACTIVATION; FIBROBLAST; HORMONAL REGULATION; HORMONE ACTION; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; LIGAND BINDING; PROTEIN BINDING; PROTEIN DEGRADATION; WESTERN BLOTTING;

EID: 0032983591     PISSN: 09188959     EISSN: None     Source Type: Journal    
DOI: 10.1507/endocrj.46.suppl_s63     Document Type: Conference Paper

References (11)

1. Shimasaki S, Ling N (1991) Identification and molecular characterization of insulin-like growth factor binding proteins (IGFBP-1, -2, -3, -4, -5 and -6). Prog in Growth Factor Res 3: 243-266.
2. Jones JJ, Clemmons DR (1996) Insulin-like growth factors and their binding proteins: Biological actions. Endocr Rev 16: 3-34.
3. Yateman ME, Clafey DC, Hughes SCC, Hughes C, Frost VG, Wass JAH, Holly JMP (1993) Cytokines modulate the sensitivity of human fibroblasts to stimulation with insulin-like growth factor-I (IGF-I) by alterung endogenous IGF binding protein production. J Endocrinol 137: 151-159.
4. Hossenlop P, Seurin D, Segovia-Quuinson B, Hardouin S, Binoux M (1986) Analysis of serum insulin-like growth factor binding proteins using Western blotting: Use of the method for titration of the binding proteins and competitive binding studies. Anal Biochem 154: 138-143.
5. Jones JI, Gockerman A, Busby WH Jr, Camacho-Hubuner C, Clemmons DR (1993) Extracellular matrix contains insulin-like growth factor binding protein-5: Potentiation of the effects of IGF-I. J Cell Biol 121: 679-687.
6. Martin JL, Coverley JA, Baxter RC (1994) Regulation of immunoreactive insulin-like growth factor binding protein-6 in normal and tranformed human fibroblasts. J Biol Chem 269: 11470-11477.
7. Powell DR, Liu F, Baker BK, Hintz RL, Durham SK, Brewer ED, Frane JW, Tonshoff B, Mehls O, Wingen A-M, Watkins SL, Hogg RJ, Lee PDK (1997) Insulin-like growth factor-binding protein-6 levels are elevated in serum of children with chronic renal failure: A report of the Southeast pediatric inferiorly study group. J Clin Endocrinol Metab 82: 2978-2984.
8. Conveyor CA, Kiefer MC, Zapf J (1993) Posttranslational regulation of insulin-like growth factor binding protein-4 in normal and transformed human fibroblasts. J Clin Invest 91: 1129-1137.
9. Guidice LC, Farrel EM, Pham H, Lamson G, Rosenfeld RG (1990) Insulin-like growth factor binding proteins in maternal serum throughout gestation and in the puerperium: Effects of a pregnancy-associated serum protease activity. J Clin Endocrinol Metab 71: 806-816.
10. Hasegawa Y, Hasegawa T, Koni H, Aso T, Tanaka N, Kotoh S, Yamada M, Tsuchiya Y (1995) Proteolytic activity of IGFBP-3 in various clinical conditions during childhood studied by means of Western immunoblotting. Endocr J 42: 569-576.
11. Davenport ML, Isley WL, Pucilowska JB, Pemberton LB, Lyman B, Underwood LE, Clemmons DR (1992) Insulin-like growth factor-binding protein-3 proteolysis is induced after elective surgery. J Clin Endocrinol Metab 75: 590-595.