Cotinine (a metabolite of nicotine) suppresses the growth of hematopoietic progenitor cells at the concentration range equivalent to its serum levels in smokers

Stem Cells

Volumn 17, Issue 2, 1999, Pages 125-126

  Takahashi, M ^a   Shigeno, N ^a   Narita, M ^a   Takahashi, H ^a   Furukawa, T ^a   Koike, T ^a   Aizawa, Y ^a  

^a NIIGATA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COTININE; NICOTINE;

BLOOD LEVEL; BONE MARROW CELL; BURST FORMING UNIT E; COLONY FORMING UNIT E; COLONY FORMING UNIT GM; CONTROLLED STUDY; GRANULOPOIESIS; GROWTH INHIBITION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; LETTER; MONONUCLEAR CELL; NORMAL HUMAN; SMOKING;

NICOTIANA TABACUM;

EID: 0032983048     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.170125     Document Type: Letter

References (5)

1. 1 Whitehead TP, Robinson D, Allaway SL, et al. The effects of cigarette smoking and alcohol consumption on blood haemoglobin, erythrocytes and leucocytes: a dose related study on male subjects. Clin Lab Haematol 1995: 17: 131–138.
2. 2 Takahashi M, Terao A, Murata M, et al. Hematological abnormalities caused by smoking: the association with myelodysplastic syndrome. Niigata Med J 1997: 111: 647–655.
3. 3 Wynder EL, Hoffmann D. Tobacco and health: a societal challenge. New Engl J Med 1979: 300: 894–903.
4. 4 Muranaka H, Tamada T, Higashi E, et al. Microdetermination of nicotine and its metabolites in biological fluid. III. Effect of smoking on plasma nicotine, plasma cotinine and other biochemical variables in human being. Rinshokagaku 1981: 10: 127–135.
5. 5 Erslev AJ. Secondary polycythemia. In: Beutler E, Lichtman MA, Coller BS, et al., eds. Williams Hematology. 5th Edition. New York: McGraw‐Hill, 1995 ; 714–726.