Regulation of serum leptin levels by gonadal function in rats

European Journal of Endocrinology

Volumn 140, Issue 5, 1999, Pages 468-473

  Pinilla, L ^a   Seoane, L M ^b   Gonzalez, L ^a   Carro, E ^b   Aguilar, E ^a   Casanueva, F F ^b   Dieguez, C ^b,c  

^a UNIVERSITY OF CÓRDOBA   (Spain)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^c UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; LEPTIN; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; ESTRUS CYCLE; FEMALE; GONAD FUNCTION; HORMONAL REGULATION; MALE; NONHUMAN; ORCHIECTOMY; OVARIECTOMY; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT;

ANIMALS; BODY WEIGHT; ESTRADIOL; ESTRUS; FEMALE; GONADS; HORMONE REPLACEMENT THERAPY; LEPTIN; MALE; ORCHIECTOMY; OVARIECTOMY; PROTEINS; RATS; RATS, WISTAR; SEX CHARACTERISTICS; TESTOSTERONE;

EID: 0032982667     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1400468     Document Type: Article

References (25)

1. Zhang Y, Proenca R, Maffei M, Barone M, Leopolod L & Friedman J. Positional cloning of the mouse obese gene and its human homologue. Nature 1994 372 425-432.
2. Campfield LA, Smith FJ, Guisez Y, Devos R & Burn P. Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 1995 269 546-549.
3. Meier CA. Leptin secretion and action: an update. European Journal of Endocrinology 1996 134 543-544.
4. Perron F, Considine RV, Peino R, Lado IG, Dieguez C & Casanueva FF. Serum leptin concentrations in patients with anorexia nervosa, bullimia nervosa and non-specific eating disorders correlate with the body mass index but are independent of the respective disease. Clinical Endocrinology 1997 46 289-293.
5. Grinsponn S, Gulick T, Askari H, Landt M, Lee K, Anderson E et al. Serum leptin levels in women with anorexia nervosa. Journal of Clinical Endocrinology and Metabolism 1996 81 3861-3863.
6. Chehab FF, Mounzih K, Lu R & Lim ME. Early onset of reproductive function in normal female mice treated with leptin. Science 1997 275 889-891.
7. Cheung CC, Thornton JE, Kuijper JL, Weigle DS. Clifton DK & Steiner RA. Leptin is a metabolic gate for the onset of puberty in the female rat. Endocrinology 1997 138 855-858.
8. Barash IA, Cheung CC, Weigle DS, Ren H, Kabigting EB, Kuijper JL et al. Leptin is a metabolic signal to the reproductive system. Endocrinology 1996 137 3144-3147.
9. Chehab FF, Lim ME & Lu R. Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nature Genetics 1996 12 318-320.
10. Carro E, Pinilla L, Seoane ML, Considine RV, Aguilar E, Casanueva FF et al. Influence of endogenous leptin tone on oestrous cycle and LH pulsatility in female rats. Neuroendocrinology 1997 66 375-377.
11. Zachow RJ & Magoffin DA. Direct intraovarian effects of leptin: impairment of the synergistic action of insulin-like growth factor-I on follicle-stimulating hormone-dependent estradiol-17β production by rat ovarian granulosa cells. Endocrinology 1997 138 847-850.
12. Rosenbaum M, Nicolson M, Hirsch J, Heymsfield SB, Gallagher D, Chu F et al. Effects of gender, body composition, and menopause on plasma concentrations of leptin. Journal of Clinical Endocrinology and Metabolism 1996 81 3424-3427.
13. Garcia Mayor RV, Andrade A, Rios M, Lage M, Dieguez C & Casanueva FF, Serum leptin levels in normal children: relationship to age, gender, body mass index, pituilary-gonadal hormones, and pubertal stage. Journal of Clinical Endocrinology and Metabolism 1997 82 2849-2855.
14. Tome MA, Lage M, Camiña JP. Garcia-Mayor R. Dieguez C & Casanueva FF. Gender-based differences in serum leptin levels from umbilical cord blood at delivery. European Journal of Endocrinology 1997 137 655-658.
15. Schubring C, Kiess W, Englaro P, Rascher W, Dotsch J, Hanitsch S et al. Levels of leptin in maternal serum, amniotic fluid, and arterial and venous cord blood: relation to neonatal and placental weight. Journal of Clinical Endocrinology and Metabolism 1997 82 1480-1483.
16. Matsuda J, Ypkota I, Iida M, Murakami T, Naito E, Ito M et al. Serum leptin concentrations in cord blood: relationship to birth weight and gender. Journal of Clinical Endocrinology and Metabolism 1997 82 1642-1644.
17. Montague CT, Prins JB, Sanders L, Digby JE & O'Rahilly S. Depot and sex-specific differences in human leptin mRNA expression: implications for the control of regional fat distribution. Diabetes 1997 46 342-347.
18. Pombo M, Herrera E, Considine RV, Hermida RC, Galvez MJ, Martin T et al. Nocturnal rise of leptin in normal prepubertal and pubertal children and in patients with perinatal stalk-transection syndrome. Journal of Clinical Endocrinology and Metabolism 1997 82 2751-2754.
19. Clayton PE, Gill MS, Hall CM, Tillmann U, Whatmore AJ & Price A. Serum leptin through childhood and adolescence. Clinical Endocrinology 1997 46 727-753.
20. Wade GN, Gray JM & Bartness TJ. Gonadal influences of adiposity. International Journal of Obesity 1985 9 83-92.
21. Murakami T, Iida M & Shimu K. Dexamethasone regulates obese expression in isolated rat adipocytes. Biochemical and Biophysical Research Conmunications 1995 214 1260-1267.
22. Casabiell X, Piñeiro V, Peino R, Lage M, Camiña J. Gallego R et al. Gender differences in both spontaneous and stimulated leptin secretion by human omental adipose tissue in vitro: dexamethasone and estradiol stimulate leptin release in women but not in men samples. Journal of Clinical Endocrinology and Metabolism 1998 83 2149-2155.
23. Shimizu H, Shimomura Y, Nakanishi Y, Futawari T, Ohtani K & Sato N. Estrogen increases in vivo leptin production in rats and human subjects. Journal of Endocrinology 1997 154 285-292.
24. Lonnquist F, Arner P, Nodfrords L & Schalling M. Overexpression of the obese (ob) gene in adipose tissue of human obese subjects. Nature Medicine 1995 1 950-953.
25. Jockenhovel F, Blum WF, Vogel E, Englaro P, Muller D, Reinwein D et al. Testosterone substitution normalizes elevated serum leptin levels in hypogonadal men. Journal of Clinical Endocrinology and Metabolism 1997 82 2510-2513.