Localization of 4-hydroxy-2-nonenal-modified proteins in kidney following iron overload

Free Radical Biology and Medicine

Volumn 26, Issue 9-10, 1999, Pages 1181-1193

  Zainal, Theodor A ^a   Weindruch, Richard ^b,d   Szweda, Luke I ^e   Oberley, Terry D ^b,c  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c WILLIAM S MIDDLETON MEMORIAL VETERANS HOSPITAL   (United States)

^d Clinical Science Center   (United States)

^e CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

4 Hydroxy 2 nonenal; Aldehydes; Ferric nitrilotriacetate; Free radicals; Immunogold; Iron; Lipid peroxidation; Reactive oxygen species

Indexed keywords

4 HYDROXYNONENAL; CELL PROTEIN; MALONALDEHYDE; NITRILOTRIACETATE IRON;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; IMMUNOGOLD STAINING; IRON OVERLOAD; LIPID ANALYSIS; LIPID PEROXIDATION; MALE; MICROSCOPY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; RAT;

ANIMALIA;

EID: 0032982507     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(98)00312-8     Document Type: Article

References (35)

1. Okada S. Iron-induced tissue damage and cancer the role of reactive oxygen species-free radicals . Pathol. Int. 46:1996;311-332.
2. Ebina Y., Okada S., Hamazaki S., Ogino F., Li J.-L., Midorikawa O. Nephrotoxicity and renal cell carcinoma after use of iron- and aluminum-nitrilotriacetate complexes in rats. J. Natl. Cancer Inst. 76:1986;107-113.
3. Li J.-L., Okada S., Hamazaki S., Midorikawa O. Subacute nephrotoxicity and induction of renal cell carcinoma in mice treated with ferric nitrilotriacetate. Cancer Res. 47:1987;1867-1869.
4. Liu M., Okada S., Kawabata T. Radical-promoting free iron level in serum of rats treated with ferric nitrilotriacetate comparison with other iron chelate complexes . Acta Med. Okayama. 45:1993;401-408.
5. Zhang D., Okada S., Kawabata T., Yasuda T. An improved simple colorimetric method for quantitation of non-transferrin-bound iron in serum. Biochem. Mol. Biol. Int. 35:1995;635-641.
6. Toyokuni S., Uchida K., Okamoto K., Hattori-Nakakuki Y., Hiai H., Stadtman E.R. Formation of 4-hydroxy-2-nonenal-modified proteins in the renal proximal tubules of rats treated with a renal carcinogen, ferric nitrilotriacetate. Proc. Natl. Acad. Sci. USA. 91:1994;2616-2620.
7. 7-12 acyloins in the kidney of Wistar rats after treatment with a renal carcinogen, ferric nitrilotriacetate. Free Radic. Biol. Med. 22:1997;1019-1027.
8. Uchida K., Fukuda A., Kawakishi S., Hiai H., Toyokuni S. A renal carcinogen ferric nitrilotriacetate mediates a temporary accumulation of aldehyde-modified proteins within cytosolic compartment of rat kidney. Arch. Biochem. Biophys. 317:1995;405-411.
9. Umemura T., Sai K., Takagi A., Hasegawa R., Kurokawa Y. Formation of 8-hydroxydeoxyguanosine (8-OH-dG) in rat kidney DNA after intraperitoneal administration of ferric nitrilotriacetate (Fe-NTA). Carcinogenesis. 11:1990;345-347.
10. Yamaguchi R., Hirano T., Asami S., Chung M.-H., Sugita A., Kasai H. Increased 8-hydroxyguanine levels in DNA and its repair activity in rat kidney after administration of a renal carcinogen, ferric nitrilotriacetate. Carcinogenesis. 17:1996;2419-2422.
11. Toyokuni S., Mori T., Dizdaroglu M. DNA base modifications in renal chromatin of Wistar rats treated with a renal carcinogen, ferric nitrilotriacetate. Int. J. Cancer. 57:1994;123-128.
12. Toyokuni S., Mori T., Hiai H., Dizdaroglu M. Treatment of Wistar rats with a renal carcinogen, ferric nitrilotriacetate, causes DNA-protein cross-linking between thymine and tyrosine in their renal chromatin. Int. J. Cancer. 62:1995;309-313.
13. Okada S., Minamiyama Y., Hamazaki S., Toyokuni S., Sotomatsu A. Glutathione cycle dependency of ferric nitrilotriacetate-induced lipid peroxidation in mouse proximal renal tubules. Arch. Biochem. Biophys. 301:1993;138-142.
14. Toyokuni S., Sagripanti J.-L. DNA single- and double-strand breaks produced by ferric nitrilotriacetate in relation to renal tubular carcinogenesis. Carcinogenesis. 14:1993;223-227.
15. Awai M., Narasaki M., Yamanoi Y., Seno S. Induction of diabetes in animals by parenteral administration of ferric nitrilotriacetate. Am. J. Pathol. 95:1979;663-674.
16. Bates G.W., Schlabach M.R. The reaction of ferric salts with transferrin. J. Biol. Chem. 248:1973;3228-3232.
17. Hamazaki S., Okada S., Toyokuni S., Midorikawa O. Thiobarbituric acid-reactive substance formation of rat kidney brush border membrane vesicles induced by ferric nitrilotriacetate. Arch. Biochem. Biophys. 274:1989;348-354.
18. Toyokuni S., Okada S., Hamazaki S., Minamiyama Y., Yamada Y., Liang P., Fukunaga Y., Midorikawa O. Combined histochemical and biochemical analysis of sex hormone dependence of ferric nitrilotriacetate-induced renal lipid peroxidation in ddY mice. Cancer Res. 50:1990;5574-5580.
19. Toyokuni S. Iron-induced carcinogenesis the role of redox regulation . Free Radic. Biol. Med. 20:1996;553-566.
20. Hamazaki S., Okada S., Ebina Y., Fujioka M., Midorikawa O. Nephrotoxicity of ferric nitrilotriacetate an electron-microscopic and metabolic study . Am. J. Pathol. 123:1986;343-350.
21. Kawabata T., Ma Y., Yamador I., Okada S. Iron-induced apoptosis in mouse renal proximal tubules after an injection of a renal carcinogen, iron-nitrilotriacetate. Carcinogenesis. 18:1997;1389-1394.
22. Uchida K., Szweda L.I., Chae H.-Z., Stadtman E.R. Immunochemical detection of 4-hydroxy-2-nonenal protein adducts in oxidized hepatocytes. Proc. Natl. Acad. Sci. USA. 90:1993;8742-8746.
23. Uchida K., Itakura K., Kawakishi S., Hiai H., Toyokuni S., Stadtman E.R. Characterization of epitopes recognized by 4-hydroxy-2-nonenal specific antibodies. Arch. Biochem. Biophys. 324:1995;241-248.
24. Uchida K., Stadtman E.R. Modification of histidine residues in proteins by reaction with 4-hydroxynonenal. Proc. Natl. Acad. Sci. USA. 89:1992;4544-4548.
25. Levine R.L., Williams J.A., Stadtman E.R., Shacter E. Carbonyl assays for determination of oxidatively modified proteins. Methods Enzymol. 233:1994;346-357.
26. Sohal R.S., Ku H.-H., Agarwal S., Forster M.J., Lal H. Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse. Mech. Ageing Dev. 74:1994;121-133.
27. Muse K.E., Oberley T.D., Sempf J.M., Oberley L.W. Immunolocalization of antioxidant enzymes in adult hamster kidney. Histochem. J. 26:1994;734-753.
28. Fukuda A., Osawa T., Oda H., Toyokuni S., Satoh K., Uchida K. Oxidative stress response in iron-induced renal carcinogenesis acute nephrotoxicity mediates the enhanced expression of glutathione S-transferase Yp isozyme . Arch. Biochem. Biophys. 329:1996;39-46.
29. Li J.-L., Okada S., Hamazaki S., Deng I-L, Midorikawa O. Sex differences in ferric nitrilotriacetate-induced lipid peroxidation and nephrotoxicity in mice. Biochim. Biophys. Acta. 922:1987;28-33.
30. Toyokuni S., Okada S., Hamazaki S., Minamiyama Y., Yamada Y., Liang P., Fukunaga Y., Midorikawa O. Combined histochemical and biochemical analysis of sex hormone dependence of ferric nitrilotriacetate-induced renal lipid peroxidation in ddy mice. Cancer Res. 50:1990;5574-5580.
31. Okada S., Fukunaga Y., Hamazaki S., Yamada Y., Toyokuni S. Sex differences in the localization and severity of ferric nitrilotriacetate-induced lipid peroxidation in the mouse kidney. Acta Pathol. Jpn. 41:1991;221-226.
32. Cohn J.A., Tsai L., Friguet B., Szweda L.I. Chemical characterization of a protein-4-hydroxy-2-nonenal cross link immunochemical detection in mitochondria exposed to oxidative stress . Arch. Biochem. Biophys. 328:1996;158-164.
33. Chance B., Sies H., Boveris A. Hydroperoxide metabolism in mammalian organs. Physiol. Rev. 59:1979;527-605.
34. Mizzen C.A., Allis C.D. Linking histone acetylation to transcriptional regulation. Cell. Mol. Life Sci. 54:1998;6-20.
35. Park J.-W., Floyd R.A. Lipid peroxidation products mediate the formation of 8-hydroxydeoxyguanosine in DNA. Free Radic. Biol. Med. 12:1992;245-250.