Purification of closely eluting hydrophobic microcystins (peptide cyanotoxins) by normal-phase and reversed-phase flash chromatography

Journal of Chromatography A

Volumn 848, Issue 1-2, 1999, Pages 515-522

  Lawton, Linda A ^a   McElhiney, Jacqui ^a   Edwards, Christine ^b  

^a ROBERT GORDON UNIVERSITY   (United Kingdom)

^b Dyax Corp   (United States)

Author keywords

Flash chromatography; Microcystins; Peptides; Toxins

Indexed keywords

CYANOGINOSIN; HEPTAPEPTIDE;

ARTICLE; PRIORITY JOURNAL; PROTEIN PURIFICATION; REVERSED PHASE LIQUID CHROMATOGRAPHY;

EID: 0032981852     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9673(99)00462-8     Document Type: Article

References (12)

1. Carmichael W.W. Adv. Bot. Res. 27:1997;212.
2. Soll M.D., Williams M.C. J. S. Afr. Vet. Assoc. 56:1985;49.
3. Van Halderen A., Harding W.R., Wessels J.C., Schneider D.J., Heine E.W.P., Vandermerwe J., Fourie J.M. J. S. Afr. Vet. Assoc. 66:1995;260.
4. Lawton L.A., Edwards C., Beattie K.A., Pleasance S., Dear G.J., Codd G.A. Natural Toxins. 3:1995;50.
5. Dunn J. Br. Med. J. 312:1996;1183.
6. Jochimsen E.M., Carmichael W.W., An J.S., Cardo D.M., Cookson S.T., Holmes C.F.B., Antunes M.B.D., de Melo D.A., Lyra T.M., Barreto V.S.T., Azevedo S.M.F.O., Jarvis W.R. New Engl. J. Med. 338:1998;873.
7. Azevedo S.M.F., Evans W.R., Carmichael W.W., Namikoshi M. J. Appl. Phycol. 6:1994;261.
8. Harada K.-I., Suzuki M., Dahlem A.M., Beasley V.R., Carmichael W.W., Rinehart K.L. Toxicon. 26:1988;433.
9. Lawton L.A., Edwards C., Codd G.A. Analyst. 119:1994;1525.
10. Meriluoto J.A.O., Eriksson J.E., Harada K.-I., Dahlem A.M., Sivonen K., Carmichael W.W. J. Chromatogr. 509:1990;390.
11. Edwards C., Lawton L.A., Coyle S.M., Ross P. J. Chromatogr. A. 734:1996;163.
12. Edwards C., Lawton L.A., Coyle S.M., Ross P. J. Chromatogr. A. 734:1996;175.