Use of 1-methyl-pyrrolidone as a solubilizing agent for determining the uptake of poorly soluble drugs

Pharmaceutical Research

Volumn 16, Issue 6, 1999, Pages 968-971

  Uch, Antje S ^a   Hesse, Ulrich ^a   Dressman, Jennifer B ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

1 Methyl 2 Pyrrolldone (NMP); Hydrocortisone; Intestinal rings; Itraconazole; Mannitol; Site specific permeability; Uptake mechanisms

Indexed keywords

2 PYRROLIDONE DERIVATIVE; HYDROCORTISONE; ITRACONAZOLE; MANNITOL;

ANIMAL TISSUE; ARTICLE; DRUG PENETRATION; DRUG SOLUBILITY; DRUG TRANSPORT; DRUG UPTAKE; INTESTINE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIFUNGAL AGENTS; HYDROCORTISONE; INTESTINAL ABSORPTION; ITRACONAZOLE; MALE; MANNITOL; MOLECULAR WEIGHT; PYRROLIDINONES; RATS; RATS, WISTAR; SOLUBILITY; TIME FACTORS;

EID: 0032981769     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012120210530     Document Type: Article

References (8)

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