Mechanisms of plaque rupture: Mechanical and biologic interactions

Cardiovascular Research

Volumn 41, Issue 2, 1999, Pages 369-375

  Arroyo, Luis H ^a   Lee, Richard T ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Collagen; Mechanical stress; Metalloproteinases; Unstable plaque

Indexed keywords

ATHEROGENESIS; ATHEROSCLEROTIC PLAQUE; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY THROMBOSIS; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; GENE OVEREXPRESSION; HISTOPATHOLOGY; MECHANICAL STRESS; MORBIDITY; MORTALITY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; STRESS STRAIN RELATIONSHIP; THROMBOGENESIS; VASCULAR ENDOTHELIUM; YOUNG MODULUS;

ANIMALS; ARTERIES; BIOMECHANICS; CORONARY ARTERIOSCLEROSIS; EXTRACELLULAR MATRIX; HUMANS; LIPID METABOLISM; METALLOENDOPEPTIDASES; MUSCLE, SMOOTH, VASCULAR; MYOCARDIAL INFARCTION;

EID: 0032981584     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(98)00308-3     Document Type: Review

References (56)

1. Murray CJL, Lopez AD. The global burden of disease. Global burden of disease and injury series. Boston, MA: Harvard School of Public Health/Harvard University Press, 1996:1-34.
2. Goldman L., Cook E.F. The decline in ischemic heart disease mortality rates. An analysis of the comparative effects of medical interventions and changes in lifestyle. Ann Intern Med. 101:1984;825-836.
3. Constantinides P. Plaque fissure in human coronary thrombosis. J Atheroscler Res. 6:1966;1-17.
4. Davies M.J., Thomas A. Thrombosis and acute coronary-artery lesions in sudden cardiac ischemic death. New Engl J Med. 310:1984;1137-1140.
5. Farb A., Tang A.L., Burke A.P.et al. Sudden coronary death: frequency of active coronary lesions, inactive coronary lesions, and myocardial infarction. Circulation. 92:1995;1701-1709.
6. Davies M.J., Bland J.M., Hangartener J.R.W., Angelini A., Thomas A.C. Factors influencing the presence or absence of acute coronary artery thrombi in sudden cardiac ischemic death. Eur Heart J. 10:1989;203-208.
7. Gertz S.D., Roberts W.C. Hemodynamic shear force in rupture of coronary arterial atherosclerotic plaques. Am J Cardiol. 66:1990;1368-1372.
8. Binns R.L., Ku D.N. Effects of stenosis in wall motion: a possible mechanism of stroke and transient ischemic attack. Arteriosclerosis. 9:1989;842-847.
9. Vito R.P., Whang M.C., Giddens D.P., Zarins C.K., Glagov S. Stress analysis of the diseased arterial cross-section. ASME Adv Bioeng Proc. 19:1990;273-276.
10. Barger A.C., Beeuwkes R., Lainey L.L., Silverman K.J. Hypothesis: vasa vasorum and neo-vascularization of human coronary arteries: a possible role in the pathophysiology of atherosclerosis. New Engl J Med. 88:1991;8154-8158.
11. Little W.C., Constantinescu M., Applegate R.J.et al. Can coronary angiography predict the site of subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease? Circulation. 78:1988;1157-1166.
12. Ambrose J.A., Tannenbaum M.A., Alexopoulos D.et al. Angiographic progression of coronary artery disease and the development of myocardial infarction. J Am Coll Cardiol. 12:1988;56-62.
13. Vlaodaver Z., French R., van Tassel R.A., Edwards J.E. Correlation of the antemortem coronary angiogram and the postmortem specimen. Circulation. 47:1973;162-168.
14. Arnett E.N., Isner J.M., Redwood C.R.et al. Coronary artery narrowing in coronary heart disease: comparison of cine-angiography and necropsy findings. Ann Intern Med. 91:1979;350-356.
15. Levine G.N., Kearney J.F., Vita J.A. Cholesterol reduction in cardiovascular disease. New Engl J Med. 332:1995;512-521.
16. Farb A., Burke A.P., Tang A.L.et al. Coronary plaque erosion without rupture into a lipid core: a frequent cause of coronary thrombosis in sudden coronary death. Circulation. 93:1996;1354-1363.
17. Lee RT, Schoen FJ. Pathology of unstable coronary plaque. In: Rutherford JD, editor. Unstable angina. New York: Marcel Dekker, 1991:1-25.
18. Lee R.T., Kamm R.D. Vascular mechanics for the cardiologists. J Am Coll Cardiol. 23:1994;1289-1295.
19. Richardson P.D., Davies M.J., Born G.V.R. Influence of plaque configuration and stress distribution on fissuring of coronary atherosclerotic plaques. Lancet. 2:1989;941-944.
20. Cheng G.C., Loree H.M., Kamm R.D., Fishbein M.C., Lee R.T. Distribution of circumferential mechanical stress in ruptured and stable atherosclerotic lesions: a structural analysis with histopathological correlation. Circulation. 87:1993;1179-1187.
21. Born GVR, Richardson PD. Mechanical properties of human atherosclerosis. In: Glagov S, Newman W, Schaffer S, editors. Pathobiology of the human atherosclerotic plaques. New York: Springer-Verlag, 1990:413-424.
22. Loree H.M., Kamm R.D., Stringfellow R.G., Lee R.T. Effects of fibrous cap thickness on peak circumferential stress in model atherosclerotic vessels. Circ Res. 71:1992;850-858.
23. McCord B.N., Ku D.N. Mechanical rupture of the atherosclerotic plaque fibrous cap. Trans. 1993 ASME Bioeng Conf. 24:1993;324-326.
24. Binns R.L., Ku D.N. Effect of stenosis on wall motion. A possible mechanism of stroke and transient ischemic attack. Arteriosclerosis. 9:1989;842-847.
25. Lendon C.L., Briggs A.D., Born G.V.R., Burleigh M.C., Davies M.J. Mechanical testing of connective tissue in the search for determinants of atherosclerotic plaque cap rupture. Biochem Soc Trans. 16(6):1988;1032-1033.
26. Libby P, Lee RT. Role of activated macrophages and T-lymphocytes in rupture of coronary plaques. In: Braumwald E, editor. Heart disease: a textbook of cardiovascular medicine (Suppl 2). Philadelphia: Saunders, 1995:1-9.
27. Ross R. The pathogenesis of atherosclerosis: an update. New Engl J Med. 314:1986;488-500.
28. Davies M.J. A macro and micro view of coronary vascular insult in ischemic heart disease. Circulation. 82(suppl II):1990;38-46.
29. Amento E.P., Ehsani N., Palmer H., Libby P. Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells. Arterioscler Thromb. 11:1991;1223-1230.
30. Lee R.T., Berditchevski F., Cheng G.C., Hemler M.E. Integrin-mediated collagen matrix reorganization by cultured human vascular smooth muscle cells. Circ Res. 76:1995;209-214.
31. Van der Wal A.C., Becker A.E., van der Loos C.M., Das P.K. Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology. Circulation. 89:1994;36-44.
32. Falk E. Why do plaques rupture? Circulation. 86(suppl III):1992;30-42.
33. Romero P.R., Falk E., Palacios I.et al. Macrophage infiltration in acute coronary syndromes. Implications for plaque rupture. Circulation. 90:1994;775-778.
34. Hanson G.K., Holm J., Johansson L. Detection of activated T-lymphocytes in human atherosclerotic plaque. Am J Pathol. 135:1989;169-175.
35. Geng Y., Wu Q., Muszynski M., Hansson G.K., Libby P. Apoptosis of vascular smooth muscle cells induced by in vitro stimulation with γ-interferon, tumor necrosis factor-α, and interleukin-1β Arterioscler Thromb Vasc Biol. 16:1996;19-27.
36. Bennet M.R., Evan G.I., Schwartz S.M. Apoptosis of human vascular smooth muscle cells derived from normal vessels and coronary atherosclerotic plaques. J Clin Invest. 95:1995;2266-2274.
37. Dollery C.M., McEwan J.R., Henney A.M. Matrix metalloproteinases and cardiovascular disease. Circ Res. 77:1995;863-868.
38. Rajagopalan S., Meng X.P., Ramasamy S., Harrison D.G., Galis Z.S. Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. J Clin Invest. 98:1996;2572-2579.
39. Lijnen H.R., Van Hoef B., Lupu F.et al. Function of the plasminogen/plasmin and matrix metalloproteinase systems after vascular injury in mice with targeted inactivation of fibrinolytic system genes. Arterioscler Thromb Vasc Biol. 18:1998;1035-1045.
40. Shofuda K., Yasumitsu H., Nishihashi A., Miki K., Miyazaki K. Expression of three membrane-type matrix metalloproteinases in rat vascular smooth muscle cells and characterization of MT3-MMPs with and without transmembrane domain. J Biol Chem. 272:1997;9749-9754.
41. Nikkari S.T., O'Brien K.D., Ferguson M.et al. Interstitial collagenase (MMP-1) expression in human carotid atherosclerosis. Circulation. 92:1995;1393-1398.
42. Galis Z., Sukhova G., Kranzhofer R., Clark S., Libby P. Macrophage foam cells from experimental atheroma constitutively produce matrix-degrading proteinases. Proc Natl Acad Sci USA. 92:1995;402-406.
43. Scandinavian Simvastatin Survival Study Group. Scandinavian simvastatin survival study (4S). Lancet 1994;334:1383-1389.
44. Loree H.M., Tobias B.J., Gibson L.J.et al. Mechanical properties of model atherosclerotic lesion lipid pools. Arterioscler Thromb. 14:1994;230-234.
45. Lee R.T., Schoen F.J., Loree H.M., Lark M.W., Libby P. Circumferential stress and matrix metalloproteinase 1 in human coronary atherosclerosis. Implications for plaque rupture. Arterioscler Thromb Vasc Biol. 16:1996;1070-1073.
46. Leung D.Y., Glagov S., Mathews M.B. Cyclic stretching stimulates synthesis of matrix components by arterial smooth muscle cells in vitro. Science. 191:1976;475-477.
47. Mills I, Cohen CR, Sumpio BE. Cyclic strain and vascular cell biology. In: Sumpio BE, editor. Hemodynamic forces and vascular cell biology. Austin, TX: RG Landes, 1993:66-89.
48. Banes A.J., Tauzaki M., Yamamoto J.et al. Mechanoreception at the cellular level: the detection, interpretation, and diversity of responses to mechanical signals. Biochem Cell Biol. 73:1995;349-365.
49. Davies P.F., Barbee K.A., Volin M.V.et al. Spatial relationships in early signaling events of flow-mediated endothelial mechanotransduction. Annu Rev Physiol. 59:1997;527-749.
50. Takahashi M., Ishida I., Traub O., Corson M.A., Berk B.C. Mechanotransduction in endothelial cells: temporal signaling events in response to shear stress. J Vasc Res. 34:1997;212-219.
51. Yang J.-H., Briggs W.H., Libby P., Lee R.T. Small mechanical strains selectively suppress matrix metalloproteinase-1 expression by human vascular smooth muscle cells. J Biol Chem. 273:1998;6550-6555.
52. Martin D.K., Bootcov M.R., Campbell T.J., French P.W., Breit S.N. Human macrophages contain a stretch-sensitive potassium channel that is activated by adherence and cytokines. J Membr Biol. 147:1995;305-315.
53. + channels in mesenteric artery smooth muscle cells. Am J Hypertens. 7:1994;82-89.
54. Matsumoto T., Delafontaine P., Schnetzer K.J., Tong B.C., Nerem R.M. Effect of uniaxial, cyclic stretch on the morphology of monocytes/macrophages in culture. J Biomech Eng. 118:1996;420-422.
55. Aikawa M., Rabkin E., Okada Y.et al. Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma. Circulation. 97:1998;2433-2444.
56. Ridker P.M., Cushman M., Stampfer M.J., Tracy R.P., Hennekens C.H. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. New Engl J Med. 336:1997;973-979.