Substance P augments nitric oxide production and gene expression in murine macrophages

Immunopharmacology

Volumn 41, Issue 3, 1999, Pages 219-226

  Jeon, Hye Kyung ^a   Jung, Noh Pal ^a   Choi, In Ho ^b   Oh, Yung Keun ^b   Shin, Hyung Chol ^c   Gwag, Byoung Joo ^d  

^a Yonsei University   (South Korea)

^b Yonsei University Wonju   (South Korea)

^c Hallym University   (South Korea)

^d Ajou University School of Medicine   (South Korea)

Author keywords

Cold stress; Macrophages; Nitric oxide; Substance P

Indexed keywords

NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SPANTIDE; SUBSTANCE P;

ANIMAL CELL; ARTICLE; COLD STRESS; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; IMMUNE SYSTEM; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; CELL LINE; COLD; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED C57BL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; RNA, MESSENGER; SUBSTANCE P;

EID: 0032981538     PISSN: 01623109     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0162-3109(99)00033-8     Document Type: Article

References (29)

1. Blalock J.E. Production of peptide hormones and neurotransmitters by the immune system. Neuroimmunoendoclinology. 52:1992;1-24.
2. Bost K.L. Quantification of macrophage derived substance P receptor mRNA using competitive polymerase chain reaction. Adv. Exp. Med. Biol. 373:1995;219-223.
3. Carla P., Stefano M. Substance P induces secretion of immunomodulatory cytokines by human astrocytoma cells. J. Neuroimmunol. 81:1998;127-137.
4. Chandler L.J., Kathy K., Elaine R., Fulton T.C., Colin S. Angiotensin II decreases inducible nitric oxide synthase expression in rat astroglial cultures. Am. J. Physiol. 268:1995;C700-C707.
5. Cheryl C.F., Zhu G.F., Kago R., Beller D.I., Leeman S.E., Black P.H. Substance P and stress-induced changes in macrophages. Ann. New York Acad. Sci. 771:1995;472-483.
6. Colten H.R., Krause J.E. Pulmonary inflammation: a balancing act. N. Engl. J. Med. 336:1997;1094-1099.
7. Ding A.H., Nathan C.F., Stuehr D.J. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. J. Immunol. 141:1988;2407-2412.
8. Fusiwara R., Orita K. The enhancement of the immune response by pain stimulation in mice. J. Immunol. 138:1987;3699-3703.
9. Gether U., Johansen T.E., Schwartz T.W. Chimeric NK1 (substance P)/NK-3 (neurokinin B) receptors. J. Biol. Chem. 268:1993;7893-7901.
10. Hartung H.P., Toyka K.V. Activation of macrophages by substance P: induction of oxidative burst and thromboxane release. Eur. J. Pharmcol. 89:1983;301-305.
11. Ian M., Kenneth B. Substance P diminishes LPS and interferon-r-induced TGF-β1 production by cultured murine macrophages. Cell. Immunol. 183:1998;113-120.
12. Irwin M. Stress-induced immune suppression. Role of the autonomic nervous system. Ann. New York Acad. Sci. 697:1993;203-218.
13. Jeon H.K., Jung N.P., Choi I.H., Oh Y.K., Shin H.C., Gwag B.J. Comparison of macrophage activation and tumor-cytotoxicity in mouse and hamster peritoneal macrophages by cold stress. Korean J. Immunol. 19:1997;505-512.
14. Jrurissen F., Kavelaars A., Korstjens M., Broeke D., Franklin R.A., Gelfand E.W., Heijnen C.J. Monocytes express a nonneurokinin substance P receptor that is functionally coupled to MAP Kinase. J. Immunol. 152:1994;2987-2992.
15. Keiji Y., Uichi I., Koji O., Toshikazu S., Yasuhiro K., Masanori O., Mitsuhiro Y., Kazuyuki S. Arginine vasopressin increases nitric oxide synthesis in cytokine-stimulated rat cardiac myocytes. Hypertension. 30:1997;1112-1120.
16. Kessler J.A. Differential regulation of peptide and catecholamine characters in cultured sympathetic neurons. Neuroscience. 15:1985;827-839.
17. Kizaki T., Shujio I., Hideki O. Acute cold stress induces suppresser macrophages in mice. J. Appl. Physiol. 81:1996;393-399.
18. Lloyds D., Brindle N.P., Nallett M.B. Primary of human neutrophils by tumor necrosis factor alpha and substance P is associated with tyrosine phosphorylation. Immunology. 64:1995;220-226.
19. Lorsbach R.B., Murphy W.J., Lowenstein C.J., Snyder S.H., Russell S.W. Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. J. Biol. Chem. 268:1993;1908-1913.
20. Lotz M., Vaughan J.H., Crason D.A. Effect of neuropeptides on production of inflammatory cytokines by human monocytes. Science. 241:1988;1218-1221.
21. Lucey D.R., Novak J.M., Polonis V.R., Liu Y., Gartner S. Characterization of substance P binding to human monocytes/macrophages. Clin. Diagn. Lab. Immunol. 1:1995;330-335.
22. Macmicking J.Q., Nathan C. Nitric oxide and macrophage function. Annu. Rev. Immunol. 15:1997;323-350.
23. Miller L., Evan W.A., William J.M., Stephan W.R., Joan S.H. Progesterone inhibits inducible nitric oxide synthase gene expression and nitric oxide production in murine macrophages. J. Leukocyte Biol. 59:1996;442-450.
24. Narumi S., Finke J.H., Hamilton T.A. Interferon-r and IL-2 synergise to induce selective monokine expression in murine peritoneal macrophage. J. Biol. Chem. 265:1990;7036-7041.
25. Schmidt H.W., Walter U. NO at work. Cell. 78:1994;919-925.
26. Regoli D., Boudon A., Fauchere J-L. Receptors and antagonists for substance P and related peptides. Pharmacol. Rev. 46:1994;551-599.
27. Stanisz A.M., Scicchitano R., Pazin P., Bienenstock J., Payan D.G. Distribution of SP receptors on murine spleen and peyer's patch T and B cells. J. Immunol. 139:1987;749-754.
28. Ursin H. Stress and immunity. Ann. New York Acad. Sci. 741:1994;204-211.
29. Watson S.P., Downes C.P. Substance P induced hydrolysis of inositol phospholipids in guinea-pig ileum and rat hypothalamus. Eur. J. Pharmacol. 93:1983;245-249.