Reversal of peripheral microvascular dysfunction during long-term treatment with the angiotensin-converting enzyme inhibitor fosinopril in congestive heart failure

Journal of Cardiac Failure

Volumn 5, Issue 1, 1999, Pages 17-24

  Galatius, Søren ^a,c   Wroblewski, Henrik ^a   Sørensen, Vibeke ^a   Haunsø, Stig ^a   Nørgaard, Tove ^b   Kastrup, Jens ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b HILLERØD HOSPITAL   (Denmark)

^c Rigshospitalet   (Denmark)

Author keywords

Endothelial function; Microcirculation; Renin angiotensin; Vasoconstriction dilation

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FOSINOPRIL; PLACEBO;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONGESTIVE HEART FAILURE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DOUBLE BLIND PROCEDURE; EXERCISE; FEMALE; HEART HEMODYNAMICS; HUMAN; HUMAN TISSUE; LONG TERM CARE; MALE; MICROANGIOPATHY; MICROCIRCULATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; VASCULAR RESISTANCE;

EID: 0032981262     PISSN: 10719164     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1071-9164(99)90020-9     Document Type: Article

References (24)

1. Wroblewski H: Peripheral microvascular function in patients with idiopathic dilated cardiomyopathy: effect of cardiac transplantation. Dan Med Bull 1997;44:351-64
2. Wroblewski H, Kastrup J, Mortensen SA, Haunso S: Abnormal baroreceptor-mediated vasodilation of the peripheral circulation in congestive heart failure secondary to idiopathic dilated cardiomyopathy. Circulation 1993;87:849-56
3. Wroblewski H: Sustained paradoxical vasodilation during prolonged orthostasis in heart failure: a factor in the edema pathogenesis? Am J Physiol 1994;267:H443-8
4. Wroblewski H, Kastrup J, Norgaard T, Mortensen SA, Haunso S: Evidence of increased microvascular resistance and arteriolar hyalinosis in skin in congestive heart failure secondary to idiopathic dilated cardiomyopathy. Am J Cardiol 1992;69:769-74
5. Wroblewski H, Nørgaard T, Haunso S, Kastrup J: Microvascular distensibility in two different vascular beds in idiopathic dilated cardiomyopathy. Am J Physiol 1995; 269:H1973-80
6. Kubo SH, Rector TS, Bank AJ, Williams RE, Heifetz SM: Endothelium-dependent vasodilation is attenuated in patients with heart failure. Circulation 1991;84:1589-96
7. Lindsay DC, Holdright RD, Clarke D, Anand IS, Wilson PW, Collins P: Endothelial control of lower limb blood flow in chronic heart heart failure. Br Heart J 1996;75:469-76
8. Captopril Multicenter Research Group: A placebo-controlled trial of captopril in refractory chronic congestive heart failure. J Am Coll Cardiol 1983;2:755-63
9. Erhardt L, Maclean A, Ilgenfritz J, Gelperin K, Blumenthal M, Fosinopril Efficacy/Safety Trial (FEST) Study Group: Fosinopril attenuates clinical deterioration and improves exercise tolerance in patients with heart failure. Eur Heart J 1995;16:1892-9
10. The CONSENSUS Trial Study Group: Effect of enalapril on mortality in severe congestive heart failure: results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). N Engl J Med 1987;316:1429-35
11. Riegger GA, Kochsiek K: Vasopressin, renin and norepinephrine levels before and after captopril administration in patients with congestive heart failure due to idiopathic dilated cardiomyopathy. Am J Cardiol 1982;58:300-3
12. Galatius-Jensen S, Wroblewski H, Emmeluth C, Bie P, Haunsø S, Kastrup J: Plasma endothelin in congestive heart failure: effect of the ACE inhibitor, fosinopril. Cardiovasc Res 1996;32:1148-54
13. Dibner-Dunlab ME, Smith ML, Kinugawa T, Thames MD: Enalaprilat augments arterial and cardiopulmonary baroreflex control of sympathetic nerve activity in patients with heart failure. J Am Coll Cardiol 1996;27:358-64
14. Cody RJ, Franklin KW, Kluger J, Laragh JH: Mechanisms governing the postural response and baroreceptor abnormalities in chronic congestive heart failure: effects of acute and long-term converting-enzyme inhibition. Circulation 1982;66:135-42
15. Kastrup J: The diabetic arteriole: the impact of diabetic microangiopathy on microcirculatory control. Dan Med Bull 1988;35:334-45
16. Mancini DM, Davis L, Wexler JP, Chadwick B, LeJemtel TH: Dependence of enhanced maximal exercise performance on increased peak skeletal muscle perfusion during long-term captopril therapy in heart failure. J Am Coll Cardiol 1987;10:845-50
17. Kassis E: Baroreflex control of the circulation in patients with congestive heart failure. Dan Med Bull 1989;36:195-211
18. Brigden W, Sharpey-Schafer EP: Postural changes in peripheral blood flow in cases with left heart failure. Clin Sci 1950;9:93-100
19. Jacobsen TN, Morgan BJ, Scherrer U, Vissing SF, Lange RA, Johnson N, Ring WAS, Rahko PS, Hanson P, Victor RG: Relative contributions of cardiopulmonary and sinoaortic baroreflexes in causing sympathetic activation in the human skeletal muscle circulation during orthostatic stress. Circ Res 1993;73:367-78
20. Skagen K, Bonde-Petersen F, Henriksen O: Evidence that the arterial baroreceptors influence muscle blood flow and not subcutaneous flow in man. Acta Physiol Scand 1985; 123:405-9
21. Jacobsen TN, Nielsen HV, Kassis E, Amtorp O: Subcutaneous and skeletal muscle vascular responses in human limbs to lower body negative pressure. Acta Physiol Scand 1992;144:247-52
22. Creager MA, Hirsch AT, Dzau VJ, Nabel EG, Cutler SS, Colucci WS: Baroreflex regulation of regional blood flow in congestive heart failure. Am J Physiol 1990;258:H1409-14
23. Wroblewski H, Sindrup JH, Nørgaard T, Haunsø S, Kastrup J: Effects of orthotopic cardiac transplantation on structural microangiopathy and abnormal hemodynamics in idiopathic dilated cardiomyopathy. Am J Cardiol 1996; 77:281-5
24. Nakamura M, Funakoshi T, Arakawa N, Yoshida H, Makita S, Hiramori K: Effects of angiotensin-converting enzyme inhibitors on endothelium-dependent peripheral vasodilation in patients with chronic heart failure. J Am Coll Cardiol 1994;24:1321-7