Pathomorphological aspects of arrhythmogenic right ventricular cardiomyopathy

Giornale Italiano di Cardiologia

Volumn 29, Issue 6, 1999, Pages 719-729

  Thiene, Gaetano ^a,b   Basso, Cristina ^a   Angelini, Annalisa ^a   Calabrese, Fiorella ^a   Valente, Marialuisa ^a  

^a UNIVERSITY OF PADUA MEDICAL SCHOOL   (Italy)

^b Istituto di Anatomia Patologica   (Italy)

Author keywords

Cardiomyopathies; Dysplasia; Right ventricular arrhythmogenic cardiomyopathy

Indexed keywords

ADULT; ARRHYTHMOGENESIS; AUTOPSY; CARDIOMYOPATHY; CAUSE OF DEATH; DISEASE DURATION; DYSPLASIA; FEMALE; HEART TRANSPLANTATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MORPHOLOGY; PATHOPHYSIOLOGY; REVIEW;

ADULT; APOPTOSIS; ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA; ATROPHY; FEMALE; HEART VENTRICLES; HUMANS; MALE; MYOCARDIUM; SPORTS; TERMINOLOGY;

EID: 0032980618     PISSN: 00465968     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (59)

1. NAVA A, ROSSI L, THIENE G (eds): Arrhythmogenic right ventricular cardiomyopathy/dysplasia. Elsevier, Amesterdam, 1997.
2. THIENE G, NAVA A, CORRADO D, ROSSI L, PENNELLI N: Right ventricular cardiomyopathy and sudden death in young people. N Engl J Med 1988; 318: 129-133.
3. CORRADO D, THIENE G, NAVA A, ROSSI L, PENNELLI N: Sudden death in young competitive athletes: clinicopathologic correlation in 22 cases. Am J Med 1990; 89: 588-596.
4. BASSO C, THIENE G, CORRADO D, ANGELINI A, NAVA A, VALENTE M: Arrhythmogenic right ventricular cardiomyopathy: dysplasia, dystrophy or myocarditis? Circulation 1996; 94: 983-991.
5. MCKENNA WJ, THIENE G, NAVA A, ET AL: Diagnosis of arrhythmogenic right ventricular dysplasia/ cardiomyopathy. Br Heart J 1994; 71: 215-218.
6. CORRADO D, BASSO C, SCHIAVON M, THIENE G: Screening for hypertrophic cardiomyopathy in young athletes. N Engl J Med 1998; 339: 364-369.
7. RICHARDSON P, MCKENNA WJ, BRISTOW M, ET AL: Report of the 1995 WHO/ISFC Task Force on the definition and classification of cardiomyopathies. Circulation 1996; 93: 841-842.
8. MARCUS FI, FONTAINE G, GUIRAUDON G, ET AL: Right ventricular dysplasia. A report of 24 adult cases. Circulation 1982; 65: 384-398.
9. GERLIS LM, SCHMIDT-OTT C, HO SY, ANDERSON RH: Dysplastic conditions of the right ventricular myocardium: Uhl's anomaly vs arrhythmogenic right ventricular dysplasia. Br Heart J 1993; 69: 142-150.
10. LEE AH, MORGAN JM, GALLAGHER PJ: Arrhythmogenic right ventricular cardiomyopathy (editorial). J Pathol 1993; 171: 157-159.
11. OSLER WM: The principles and practice of medicine, 6th edition. New York, D'Appleton & Co, 1905; 820.
12. FROMENT R, PERRIN A, LOIRE R, DALLOS C: Ventricule droit papyracé du jeune adulte par dystrophie congénitale. Arch Mal Coeur 1968; 61: 477-503.
13. SEGALL HN: Parchment heart (Osler). Am Heart J 1950; 40: 948-950.
14. UHL HSM: A previously underscribed congenital malformation of the heart: almost total absence of the myocardium of the right ventricle. Bull Johns Hopkins Hosp 1952; 91: 197-209.
15. BHARATI S, CIRAULO DA, BILITCH M, ROSEN KM, LEV M: Inexcitable right ventricle and bilateral bundle branch block in Uhl's disease. Circulation 1978; 57: 636-644.
16. VECHT RJ, CARMICHAEL JS, GOPAL R, PHILIP G: Uhl's anomaly. Br Heart J 1979; 41: 676-682.
17. FONTAINE G, GUIRAUDON G, FRANK R, ET AL: Dysplasie ventriculaire droite arythmogène et maladie de Uhl. Arch Mal Coeur 1982; 4: 361-372.
18. DALLA VOLTA S, BATTAGLIA G, ZERBINI E: Auricularization of right ventricular pressure curve. Am Heart J 1961; 61: 25-33.
19. CASTLEMAN B, TOWNE VW: Presentation of case 38201. N Engl J Med 1952; 246: 785-790.
20. CUMMING GR, BOWMAN JM, WHYTEHEAD L: Congenital aplasia of the myocardium of the right ventricle (Uhl's anomaly). Am Heart J 1965; 70: 671-676.
21. BHARATI S, FELD AW, BAUERFEIND R, KATTUS AA, LEV M: Hypoplasia of the right ventricular myocardium with ventricular tachycardia. Arch Pathol Lab Med 1983; 107: 249-253.
22. FORSSMAN O, BJORKMAN G: Absence of the solid part of the right ventricular musculature. Acta Pathol Microbiol Scand 1972; 80: 263-266.
23. VIRMANI R, RABINOWITZ M, CLARK MA, MCALLISTER HA: Sudden death and partial absence of the right ventricular myocardium: a report of three cases and a review of the literature. Arch Pathol Lab Med 1982; 106: 163-167.
24. CARPENTIER HM: Myocardial fat infiltration. Am Heart J 1962; 63: 491-496.
25. LETAC B, BAYOT J, BARTHES P: Infiltration graisseuse du coeur et maladie de Uhl. A propos d'une discussion de lipomatose cardiaque. Arch Mal Coeur 1977; 70: 107-113.
26. BASSO C, THIENE G, NAVA A, DALLA VOLTA S: Arrhythmogenic right ventricular cardiomyopathy: a survey of the investigations at the University of Padua. Clin Cardiol 1997; 20: 333-336.
27. CORRADO D, BASSO C, THIENE G, ET AL: Spectrum of clinicopathologic manifestations of arrhythmogenic right ventricular cardiomyopathy/dysplasia: a multicenter study. J Am Coll Cardiol 1997; 30: 1512-1520.
28. THIENE G, ANGELINI A, BASSO C, CALABRESE F, VALENTE M: Novel heart diseases requiring transplantation. Adv Clin Path 1998; 2: 65-73.
29. MARCUS FI, FONTAINE G: Arrhythmogenic right ventricular dysplasia/cardiomyopathy: a review. Pacing Clin Electrophysiol 1995; 18: 1298-1314.
30. THIENE G, CORRADO D, NAVA A, ET AL: Right ventricular cardiomyopathy: is there evidence of an inflammatory aetiology? Eur Heart J 1991; 12 (Suppl D): 22-25.
31. BURKE AP, FARB A, TASHKO G, VIRMANI R: Arrhythmogenic right ventricular cardiomyopathy and fatty replacement of the right ventricular myocardium: are they different diseases? Circulation 1998; 97: 1571-1580.
32. MENGHETTI L, BASSO C, NAVA A, ANGELINI A, THIENE G: Spin-echo nuclear magnetic resonance for tissue characterization in arrhythmogenic right ventricular cardiomyopathy. Heart 1997; 76: 467-470.
33. BASSO C, MENGHETTI L, THIENE G: Arrhythmogenic right ventricular cardiomyopathy: in vitro myocardial tissue characterization by spin-echo nuclear magnetic resonance (abstract). Circulation 1996; 94: I-248.
34. ANGELINI A, BASSO C, NAVA A, THIENE G: Endomyocardial biopsy in arrhythmogenic right ventricular cardiomyopathy. Am Heart J 1996; 132: 203-206.
35. DALIENTO L, TURRINI P, NAVA A, ET AL: Arrhythmogenic right ventricular cardiomyopathy in young versus adult patients: similarities and difference. J Am Coll Cardiol 1995; 25: 655-664.
36. LOBO FV, HEGGTVEIT HA, BUTANY J, SILVER MD, EDWARDS JE: Right ventricular dysplasia: morphological findings in 13 cases. Can J Cardiol 1992; 8: 261-268.
37. SABEL KG, BLOMSTRÖM-LUNDQVIST C, OLSSON SB, ENESTROM S: Arrhythmogenic right ventricular dysplasia in brother and sister: is it related to myocarditis? Pediatr Cardiol 1990; 11: 113-116.
38. MATSUMORI A, KAWAI C: Coxsackie virus 63 perimyocarditis in BALB/c mice: experimental model of chronic perimyocarditis in the right ventricle. J Pathol 1980; 131: 97-106.
39. VALENTE M, CALABRESE F, ANGELINI A, CAFORIO A, BASSO C, THIENE G: Pathobiology. In: NAVA A, ROSSI L, THIENE G (eds): Arrhythmogenic right ventricular cardiomyopathy/dysplasia. Elsevier, Amesterdam, 1997; 147-158.
40. KEARNEY DL, TOWBIN JA, BRICKER JT, RADOVANCEVIC B, FRAZIER OH: Familial right ventricular dysplasia (cardiomyopathy). Ped Pathol Lab Med 1995; 15: 181-189.
41. KODAMA M, MATSUMOTO Y, FUJIWARA M: In vivo lymphocyte-mediated transfer of experimental autoimmune myocarditis. Circulation 1992; 85: 1918-1926.
42. NAVA A, THIENE G, CANCIANI B, ET AL: Familial occurrence of right ventricular dysplasia: a study involving nine families. J Am Coll Cardiol 1988; 12: 1222-1228.
43. THIENE G, BASSO C, DANIELI GA, RAMPAZZO A, CORRADO D, NAVA A: Arrhythmogenic right ventricular cardiomyopathy: a still underrecognized clinical entity. Trends Cardiovasc Med 1997; 7: 84-90.
44. RAMPAZZO A, NAVA A, DANIELI GA, ET AL: The gene for arrhythmogenic right ventricular cardiomyopathy maps to chromosome 14q23-q24. Hum Mol Genet 1994; 3: 959-962.
45. RAMPAZZO A, NAVA A, ERNE P, ET AL: A new locus for arrhythmogenic right ventricular cardiomyopathy (ARVD2) maps to chromosome 1q42-q43. Hum Mol Genet 1995; 4: 2151-2154.
46. SEVERINI GM, KRAIJINOVIC M, PINAMONTI B, ET AL: A new locus for arrhythmogenic right ventricular dysplasia on the long arm of chromosome 14. Genomics 1996; 31: 193-200.
47. RAMPAZZO A, NAVA A, MIORIN M, ET AL: ARVD4, a new locus for arrhythmogenic right ventricular cardiomyopathy, maps to chromosome 2 long arm. Genomics 1997; 45: 259-263.
48. AHMAD F, DUANXIANG LJ, KARIBE A, ET AL: Localization of a gene responsible for arrhythmogenic right ventricular dysplasia to chromosome 3p23. Circulation 1998; 98: 2791-2795.
49. COONAR AS, PROTONOTARIOS N, TSATSOPOULOU A, ET AL: Gene for arrhythogenic right ventricular cardiomyopathy with diffuse nonepidermolytic palmoplantar keratoderma and woolly hair (Naxos disease) maps to 17q21. Circulation 1998; 97: 2049-2058.
50. VALENTE M, CALABRESE F, ANGELINI A, BASSO C, THIENE G: Apoptosis in arrhythmogenic right ventricular cardiomyopathy (abstract). Circulation 1996; 94: I-471.
51. MALLAT Z, TEDGUI A, FONTALIRAN F, FRANK R, DURIGON M, FONTAINE G: Evidence of apoptosis in arrhythmogenic right ventricular dysplasia. N Engl JMed 1996; 335: 1190-1196.
52. VALENTE M, CALABRESE F, THIENE G, ET AL: In vivo evidence of apoptosis in arrhythmogenic right ventricular cardiomyopathy. Am J Pathol 1998; 152: 479-484.
53. JAMES TN: Normal and abnormal consequences of apoptosis in the human heart. From postnatal morphogenesis to paroxysmal arrhythmias. Circulation 1994; 90: 556-573.
54. KERR JFR, WYLLIE AH, CURRIE AR: Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972,26: 239-257.
55. JAMES TM, NICHOLS MM, SAPIRE DW, DI PATRE, PL, LOPEZ SM: Complete heart block and fatal right ventricular failure in an infant. Circulation 1996; 93: 1588-1600.
56. GAVRIELI Y, SHERMAN Y, BEN- SASSON SA: Identification of programmed cell death in situ via specific labelling of nuclear DNA fragmentation. J Cell Biol 1992; 119: 493-501.
57. MISAO J, HAYAKAWA Y, OHNO M, NATO S, FUJWARA T, FUJWARA H: Expression of bcl-protein, an inhibitor of apoptosis, in ventricular myocytes of human hearts with myocardial infarction. Circulation 1996; 94: 1506-1512.
58. KAJSTURA J, MANSUKHANI M, CHENG W, ET AL: Programmed cell death and expression of the protoncogene bcl-2 in myocytes during postnatal maturation of the heart. Exp Cell Res 1995; 219: 110-121.
59. OLIVETTI G, ABBI R, QUAINI F, ET AL: Apoptosis in the failing human heart. N Engl J Med 1997; 336: 1131-1141.