Long-term estrogen replacement coordinately decreases trkA and β-PPT mRNA levels in dorsal root ganglion neurons

Experimental Neurology

Volumn 155, Issue 2, 1999, Pages 260-267

  Liuzzi, Francis J ^a   Scoville, Sheila A ^a   Bufton, Susan M ^a  

^a EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

Author keywords

Analgesia; Estrogen receptor; NGF; Nociception; Ovariectomy; Substance P

Indexed keywords

CONJUGATED ESTROGEN; ESTROGEN; ESTROGEN RECEPTOR; MESSENGER RNA; NERVE GROWTH FACTOR RECEPTOR; NEUROPEPTIDE K; PREPROTACHYKININ;

ANALGESIA; ANIMAL EXPERIMENT; ARTICLE; CHRONOTHERAPY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; ESTROGEN THERAPY; FEMALE; GENE EXPRESSION REGULATION; MENOPAUSE; NOCICEPTION; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; SKIN SENSITIVITY; SPINAL GANGLION;

EID: 0032980353     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1998.6999     Document Type: Article

References (38)

1. Amandusson A., Hermanson O., Blomqvist A. Estrogen receptor-like immunoreactivity in the medullary and spinal dorsal horn of the female rat. Neurosci. Lett. 196:1995;25-28.
2. Amandusson A., Hermanson O., Blomqvist O. Colocalization of oestrogen receptor immunoreactivity and preproenkephalin mRNA expression to neurons in the superficial laminae of the spinal and medullary dorsal horns of rats. Eur. J. Neurosci. 8:1996;2440-2445.
3. Bereiter D. A., Barker D. J. Facial receptive fields of trigeminal neurons: Increased size following estrogen treatment in female rats. Neuroendocrinology. 18:1975;115-124.
4. Bereiter D. A., Barker D. J. Hormone-induced enlargement of receptive fields in trigeminal mechanoreceptive neurons. I. Time course, hormone, sex and modality specificity. Brain Res. 184:1980;395-410.
5. Bereiter D. A., Stanford L. R., Barker D. J. Hormone-induced enlargement of receptive fields in trigeminal mechanoreceptive neurons. II. Possible mechanisms. Brain Res. 184:1980;411-423.
6. Bettini E., Pollio G., Santagati S., Maggi A. Estrogen receptor in rat brain: Presence in the hippocampal formation. Neuroendocrinology. 56:1992;502-508.
7. Bhavani B. R. Pharmacokinetics and pharmacodynamics of conjugated equine estrogens: Chemistry and metabolism. Proc. Soc. Exp. Biol. Med. 217:1998;6-16.
8. Butcher R. L., Collins W. E., Fugo N. W. Plasma concentration of LH, FSH, prolactin, progesterone and estradiol-17β throughout the 4-day estrus cycle of the rat. Endocrinology. 94:1974;1704-1708.
9. Cogan R., Spinnato J. A. Pain and discomfort thresholds in late pregnancy. Pain. 27:1986;63-68.
10. Frye C. A., Bock B. C., Kanarek R. B. Hormonal milieu affects tailflick latency in female rats and may be attenuated by access to sucrose. Physiol. Behav. 52:1992;699-702.
11. Gibbs R. B. Levels of trkA and BDNF mRNA, but not NGF mRNA, fluctuate across the estrous cycle and increase in response to acute hormone replacement. Brain Res. 787:1998;259-268.
12. Gibbs R. B., Wu d.-H., Hersh L., Pfaff D. W. Effects of estrogen replacement on relative levels of ChAT, TrkA and nerve growth factormessenger RNAs in the basal forebrain and hippocampal formation of adult rats. Exp. Neurol. 129:1994;70-80.
13. Gintzler A. R. Endorphin-mediated increases in pain threshold during pregnancy. Science. 210:1980;193-195.
14. Henken D. B., Tessler A., Chesselet M.-F., Hudson A., Baldino F. Jr., Murray M. In situ hybridization of mRNA for β-preprotachykinin and preprosomatostatin in adult rat dorsal root ganglia: Comparison with immunocytochemical localization. J. Neurol. 17:1988;671-681.
15. Herren R. Y. The effect of high and low female sex hormone concentrations on the two-point threshold of pain and touch and upon tactile sensitivity. J. Exp. Psychol. 16:1933;324-327.
16. Iwasaki H., Collins J. G., Saito Y., Kerman-Hinds A. Naloxone-sensitive, pregnancy-induced changes in behavioral responses to colorectal distention: Pregnancy-induced analgesia to visceral stimulation. Anesthesiol. 74:1991;927-933.
17. Komisaruk B. R., Adler N. T., Hutchison J. Genital sensory field: Enlargement by estrogen treatment in female rats. Science. 178:1972;1295-1298.
18. Kow L.-M., Pfaff D. W. Effects of estrogen treatment on the size of receptive field and response threshold of pudendal nerve in the rat. Neuroendocrinology. 13:1973/1974;299-313.
19. Kow L.-M., Pfaff D. W. Responses of single units in sixth lumbar dorsal root ganglion of female rats to mechanostimulation relevant for lordosis reflex. J. Physiol. 42:1979;203-213.
20. Krause J. E., Chirgwin J. M., Carter M. S., Xu Z. S., Hershey A. D. Three rat preprotachykinin mRNAs encode the neuropeptides substance P and neurokinin A. Proc. Natl. Acad. Sci. USA. 84:1987;881-885.
21. Levitz M., Young B. K. Estrogen in pregnancy. Vit. Horm. 35:1977;109-147.
22. Lindsay R. M., Harmar A. J. Nerve growth factor regulates expression of neuropeptide genes in adult sensory neurons. Nature. 337:1989;362-364.
23. McNamara G. Silver grain counting. J. NIH Res. 5:1993;70.
24. Medina V. M., Dawson-Basoa M. E., Gintzler A. R. 17β-estradiol and progesterone positively modulate spinal cord dynorphin: Relevance to the analgesia of pregnancy. Neuroendocrinology. 58:1993;310-315.
25. Oblinger M. M., Pickett J., Talaghany N., Don Carlos L. Expression and regulation of estrogen receptor (ER) and its mRNA in a subpopulation of rat dorsal root ganglion neurons. Soc. Neurosci. Abstr. 20:1994;1693.
26. Papka R. E., Srinivasan B., Miller K. E., Hayashi S. Localization of estrogen receptor protein and estrogen receptor messenger RNA in peripheral autonomic and sensory neurons. Neuroscience. 79:1997;1153-1163.
27. Sarajari S., Pickett J., Taleghany N., Oblinger M. M. Differential regulation of calcitonin gene-related peptide and substance P by estrogen in rat sensory neurons. Soc. Neurosci. Abstr. 21:1995;2014.
28. Scoville S. A., Bufton S. M., Liuzzi F. J. Estrogen regulates neurofilament gene expression in adult female rat dorsal root ganglion neurons. Exp. Neurol. 146:1997;596-599.
29. Scoville S. A., Bufton S. M., Liuzzi F. J. Effects of chronic ovariectomy and estrogen replacement on lumbar dorsal root ganglion trkA and PPT mRNA levels. Soc. Neurosci. Abstr. 23:1997;1709.
30. Simerly R. B., Chang C., Muramatsu M., Swanson L. W. Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: An in situ hybridization study. J. Comp. Neurol. 294:1990;76-95.
31. Smeyne R. J., Klein R., Schnapp A., Long L. K., Bryant S., Lewin A., Lira S. A., Barbacid M. Severe sensory and sympathetic neuropathies in mice carrying a disrupted trk/NGF receptor gene. Nature. 368:1994;246-249.
32. Sohrabji F., Miranda R. C., Toran-Allerand C. D. Estrogen differentially regulates estrogen and nerve growth factor receptor mRNAs in adult sensory neurons. J. Neurosci. 14:1994;459-471.
33. Toran-Allerand C. D., Miranda R. C., Bentham W., Sohrabji F., Brown E. J., Hochberg R. B., MacLusky N. J. Estrogen receptors co-localize with low-affinity NGF receptors in cholinergic neurons of the basal forebrain. Proc. Natl. Acad. Sci. USA. 89:1992;4668-4672.
34. Verge V. M. K., Merlio J.-P., Grondin J., Ernfors P., Persson H., Riopelle R. J., Hokfelt T., Richardson P. M. Co-localization of NGF binding sites, trk mRNA, and low-affinity NGF receptor mRNA in primary sensory neurons: Responses to injury and infusion of NGF. J. Neurosci. 12:1992;4011-4022.
35. Washburn S. A., Adams M. R., Clarkson T. B., Adelman S. J. A conjugated equine estrogen with differential effects on uterine weight and plasma cholesterol in the rat. Am. J. Obstet. Gynecol. 169:1993;251-256.
36. Whipple B., Josimovich J. B., Komisaruk B. R. Sensory thresholds during the antepartum, intrapartum, and postpartum periods. Intl. J. Nurs. Stud. 27:1990;213-221.
37. Wright D. E., Snider W. D. Neurotrophin receptor mRNA expression defines distinct populations of neurons in rat dorsal root ganglia. J. Comp. Neurol. 351:1995;329-338.
38. Yaksh T. L., Farb D. H., Leeman S. E., Jessel T. M. Intrathecal capsaicin depletes substance P in the rat spinal cord and produces prolonged thermal analgesia. Science. 206:1979;481-483.