Two-phase response of rat pineal melatonin to lethal whole-body irradiation with gamma rays

Physiological Research

Volumn 48, Issue 3, 1999, Pages 227-230

  Kassayova M ^a   Ahlersova E ^a   Ahlers, I ^a  

^a P J AFÁRIK UNIVERSITY   (Slovakia)

Author keywords

Ionizing radiation; Pineal melatonin; Rats; Serotonin N acetyltransferase activity

Indexed keywords

ACYLTRANSFERASE; ANTIOXIDANT; CORTICOSTERONE; MELATONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GAMMA RADIATION; HORMONE RESPONSE; HORMONE SYNTHESIS; LIGHT DARK CYCLE; MALE; NONHUMAN; PINEAL BODY; RAT; WHOLE BODY RADIATION;

EID: 0032980104     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. AHLERSOVÁ E, KASSAYOVÁ M, AHLERS I: Serum melatonin, corticosterone and thyroid hormones in irradiated rats: effect of exposure during various times of day and of light regimen: J Physiol Pharmacol 48: 435-442, 1997.
2. AHLERSOVÁ E, PÁSTOROVÁ B, KASSAYOVA M, AHLERS I, ŠMAJDA B: Reduced pineal melatonin biosynthesis in fractionally irradiated rats. Physiol Res 47: 133-136, 1998.
3. CHARRON G, SOULOUMIAC I, FOURNIER MC, CANIVENC R: Pineal rhythm in N-acetyltransferase activity and melatonin in the male badger Meles meles L. under natural daylight: relationship with the photoperiod. Pineal Res 11: 80-85, 1991.
4. DEGUCHI T, AXELROD J: Sensitive assay for serotonin N-acetyltransferase activity in rat pineal. Anal Biochem 50: 174-179, 1972.
5. FLEMMING K, GEIERHAAS B, HEMSING W, MANNIGEL U: Strahlenwirkungen und Nebennierenrinde. IV. Untersuchungen an Ratten über den ersten Corticosteroidanstieg nach Ganzkörper-Röntgenbestrahlung. Int. Radiat Biol 14: 93-105, 1968.
6. GUILLEMIN R, CLAYTON G.W, SMITH J.D, LIPSCOMB HS: Measurement of free corticosteroids in rat plasma. Physiological validation of a method. Endocrinology 63: 349-355, 1958.
7. KASSAYOVÁ M, AHLERSOVÁ E, AHLERS I: Changes of pineal N-acetyltransferase activity in gamma irradiated rats. Physiol Res 42: 167-169, 1993a.
8. KASSAYOVÁ M, AHLERSOVÁ E, AHLERS I, MILÁROVÁ R: The changes in pineal N-acetyltransferase activity, pineal and serum melatonin concentration in rats after irradiation of the head. Physiol Res 42: 419-422, 1993b.
9. KASSAYOVÁ M, AHLERSOVÁ E, PÁSTOROVÁ B, AHLERS I: The early response of pineal N-acetyltransferase activity, melatonin and catecholamine levels in rats irradiated with gamma rays. Physiol Res 44: 315-320, 1995.
10. MEFFORD IN, CHANG P, KLEIN DC, NAMBOODIRI MA, SUGDEN D, BARCHAS J: Reciprocal day/night relationship between serotonin oxidation and N-acetylation products in the rat pineal gland. Endocrinology 113: 1582-1586, 1983.
11. PARFITT A, WELLER JL, KLEIN DC: Blockade by ouabain or elevated potassium ion concentration of the adrenergic and adenosine cyclic 3′,5′-monophosphate-induced stimulation of pineal serotonin N-acetyltransferase activity. Mol Pharmacol 11: 241-255, 1975.
12. PÁSTOROVÁ B, ARENDARČÍK J: The effect of protracted exposure to gamma radiation (6.7 Gy) on the activity of monoaminooxidase in the hypothalamus of ewes in the anoestral period (in Slovak). Vet Med (Praha) 33: 735-740, 1988.
13. 60Co gamma irradiation. Strahlenterapie 151: 165-171, 1976.
14. REITER R.J: Melatonin: that ubiquitously acting pineal hormone. News Physiol Sci 6: 223-227, 1991.