Effect of metabolic acidosis on branched-chain amino acids in uremia

Pediatric Nephrology

Volumn 13, Issue 4, 1999, Pages 319-322

  Mak, Robert H K ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Acidosis; Branched chain amino acids; Hemodialysis; Leucine; Uremia; Valine

Indexed keywords

BICARBONATE; BRANCHED CHAIN AMINO ACID; CALCIUM; CREATININE; ISOLEUCINE; LEUCINE; NITROGEN; PARATHYROID HORMONE; PHOSPHATE; POTASSIUM; SODIUM; SODIUM CHLORIDE; VALINE;

ADOLESCENT; ADULT; AMINO ACID BLOOD LEVEL; ARTICLE; BICARBONATE BLOOD LEVEL; BLOOD PH; CALCIUM BLOOD LEVEL; CLINICAL ARTICLE; CREATININE BLOOD LEVEL; DIET RESTRICTION; FEMALE; HEMODIALYSIS; HUMAN; KIDNEY FAILURE; MALE; METABOLIC ACIDOSIS; PARATHYROID HORMONE BLOOD LEVEL; PHOSPHATE BLOOD LEVEL; POTASSIUM BLOOD LEVEL; PRIORITY JOURNAL; SODIUM BLOOD LEVEL; UREA NITROGEN BLOOD LEVEL; UREMIA;

ACIDOSIS; ADMINISTRATION, ORAL; ADOLESCENT; ADULT; AMINO ACIDS, BRANCHED-CHAIN; FASTING; FEMALE; HUMANS; MALE; SODIUM BICARBONATE; SODIUM CHLORIDE; UREMIA;

EID: 0032980027     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004670050617     Document Type: Article

References (16)

1. Owen WF Jr, Lew NL, Liu Y, Lowrie EG, Lazarus JM (1993) The urea reduction ratio and serum albumin concentration as predictors of mortality in patients undergoing hemodialysis. N Engl J Med 329:1001-1006
2. Kopple JD (1984) Causes of catabolism and wasting n acute or chronic renal failure. In: Robinson RR (ed) Nephrology. Springer, Berlin Heidelberg, New York, pp 1498-1514
3. Mitch WE, Walser M (1991) Nutritional therapy of the uremic patient. In: Brenner RC, Rector FC (eds) The kidney, 4th edn. Saunders, New York, pp 2186-2222
4. Mitch WE (1996) Metabolic acidosis stimulated protein metabolism in uremia. Miner Electrolyte Metab 22:62-65
5. Counahan R, El-Bishti M, Cox BD, Ogg CS, Chantler C (1976) Plasma amino acids in children and adolescents on hemodialysis. Kidney Int 10:471-477
6. McSherry E, Morris RC (1978) Attainment of normal stature with alkali therapy in infants and children with classic renal tubular acidosis. J Clin Invest 61:509-514
7. Reaich D, Channon SM, Scrimgeour CM, Goodship THJ (1992) Ammonium chloride-induced acidosis increases protein breakdown and amino acid oxidation in humans. Am J Physiol 263:E735-E739
8. Bergstrom J, Alvestrand A, Furst P (1990) Plasma and muscle free amino acids in maintenance hemodialysis patients without protein malnutrition. Kidney Int 38:108-114
9. Papdoyannakis NJ, Stefandies CJ, MeGeown M (1984) The effect of the correction of metabolic acidosis on nitrogen and protein balance of patients with chronic renal failure. Am J Clin Nutr 40:623-627
10. Harmon WE, Spinozzi N, Meyer A, Grupe WE (1981) Use of protein catabolic rate to monitor pediatric hemodialysis. Dial Transplant 10:324-330
11. Broyer M, Jean G, Dartois A, Kleinknecht C (1980) Plasma and muscle free amino acids in children at the early stages of renal failure. Am J Clin Nutr 33:1396-1401
12. Goodship THU, Mitch WE, Hoerr RA, Wagner DA, Steinman TI, Young VR (1990) Adaptation to low protein diets in renal failure: leucine turnover and nitrogen balance. J Am Soc Nephrol 1:66-75
13. Hara Y, May RC, Kelly RA, Mitch WE (1987) Acidosis, not azotemia, stimulates branched-chain amino acid catabolism in uremic rats. Kidney Int 32:808-814
14. Swendseid ME, Yamada C, Vinyard E, Figureoa WG (1968) Plasma amino acid levels in young subjects receiving diets containing 14 or 3.5 g nitrogen per day. Am J Clin Nutr 21: 1381-1383
15. Kopple JD, Swendseid ME (1975) Protein and amino acid metabolism in uremic patients undergoing maintenance hemodialysis. Kidney Int 7 [Suppl 2]:64-72
16. Baertl JM, Placko RP, Graham GG (1974) Serum proteins and plasma free amino acids in severe malnutrition. Am J Clin Nutr 27: 733-742