메뉴 건너뛰기




Volumn 129, Issue 3, 1999, Pages 649-656

Inhibition of glutathione synthesis with propargylglycine enhances N- acetylmethionine protection and methylation in bromobenzene-treated Syrian hamsters

Author keywords

Glutathione; Hamsters; Methionine; Methylation; Propargylglycine

Indexed keywords

BROMOBENZENE; GLUTATHIONE; N ACETYLMETHIONINE; PROPARGYLGLYCINE;

EID: 0032979991     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/129.3.649     Document Type: Article
Times cited : (12)

References (36)
  • 1
    • 0020055988 scopus 로고
    • Glutathione depletion sensitizes tumor cells to oxidative cytolysis
    • Arrick, B. A., Nathan, C. F., Griffith, O. W. & Cohn, Z. A. (1982) Glutathione depletion sensitizes tumor cells to oxidative cytolysis. J. Biol. Chem. 257: 1231-1237.
    • (1982) J. Biol. Chem. , vol.257 , pp. 1231-1237
    • Arrick, B.A.1    Nathan, C.F.2    Griffith, O.W.3    Cohn, Z.A.4
  • 2
    • 0019165593 scopus 로고
    • Involvement of the cystathionine pathway in the biosynthesis of glutathione by isolated rat hepatocytes
    • Beatty, P. W. & Reed, D. J. (1980) Involvement of the cystathionine pathway in the biosynthesis of glutathione by isolated rat hepatocytes. Arch. Biochem. Biophys. 204: 80-87.
    • (1980) Arch. Biochem. Biophys. , vol.204 , pp. 80-87
    • Beatty, P.W.1    Reed, D.J.2
  • 3
    • 0019332441 scopus 로고
    • Mechanism based inactivation of pig heart L-alanine transaminase by L-propargylglycine
    • Burnett, G., Marcotte, P. & Walsh, C. (1980) Mechanism based inactivation of pig heart L-alanine transaminase by L-propargylglycine. J. Biol. Chem. 255: 3487-3491.
    • (1980) J. Biol. Chem. , vol.255 , pp. 3487-3491
    • Burnett, G.1    Marcotte, P.2    Walsh, C.3
  • 4
    • 0016421339 scopus 로고
    • Biological methylation: Selected aspects
    • Cantoni, G.L. (1975) Biological methylation: selected aspects. Annu. Rev. Biochem. 44: 435-451.
    • (1975) Annu. Rev. Biochem. , vol.44 , pp. 435-451
    • Cantoni, G.L.1
  • 6
    • 0025773020 scopus 로고
    • Propargylglycine infusion effects on tissue glutathione levels, plasma amino acid concentrations and tissue morphology in parenterally fed growing rats
    • Cho, E. S., Hovanec-Brown, J., Tomanek, R. J. & Stegink, L. D. (1991) Propargylglycine infusion effects on tissue glutathione levels, plasma amino acid concentrations and tissue morphology in parenterally fed growing rats. J. Nutr. 121: 785-794.
    • (1991) J. Nutr. , vol.121 , pp. 785-794
    • Cho, E.S.1    Hovanec-Brown, J.2    Tomanek, R.J.3    Stegink, L.D.4
  • 7
    • 0021240084 scopus 로고
    • Selective inhibition of alanine aminotransferase and aspartate aminotransferase in rat hepatocytes
    • Cornell, N. W., Zuurendonk, P. F., Kerich, M. J. & Straight, C. B. (1984) Selective inhibition of alanine aminotransferase and aspartate aminotransferase in rat hepatocytes. Biochem. J. 220: 707-716.
    • (1984) Biochem. J. , vol.220 , pp. 707-716
    • Cornell, N.W.1    Zuurendonk, P.F.2    Kerich, M.J.3    Straight, C.B.4
  • 8
    • 3042934967 scopus 로고
    • Tissue sulfhydryl groups
    • Ellman, G. L. (1959) Tissue sulfhydryl groups. Arch. Biochem. Biophys. 82: 70-77.
    • (1959) Arch. Biochem. Biophys. , vol.82 , pp. 70-77
    • Ellman, G.L.1
  • 9
    • 0025362827 scopus 로고
    • Methionine metabolism in mammals
    • Finkelstein, J. D. (1990) Methionine metabolism in mammals. J. Nutr. Biochem. 1: 228-237.
    • (1990) J. Nutr. Biochem. , vol.1 , pp. 228-237
    • Finkelstein, J.D.1
  • 10
    • 0014197917 scopus 로고
    • Transsulfuration in mammals: The methionine sparing effect of cystine
    • Finkelstein, J. D. & Mudd, S. H. (1967) Transsulfuration in mammals: the methionine sparing effect of cystine. J. Biol. Chem. 242: 873-880.
    • (1967) J. Biol. Chem. , vol.242 , pp. 873-880
    • Finkelstein, J.D.1    Mudd, S.H.2
  • 11
    • 0017585973 scopus 로고
    • Sulfur amino acid activity of glutathione, DL-α-hydroxymethionine, and -ketomethionine in chicks (39906)
    • Harter, J. M. & Baker, D. H. (1977) Sulfur amino acid activity of glutathione, DL-α-hydroxymethionine, and -ketomethionine in chicks (39906). Proc. Soc Exp Biol. Med. 156: 201-204.
    • (1977) Proc. Soc Exp Biol. Med. , vol.156 , pp. 201-204
    • Harter, J.M.1    Baker, D.H.2
  • 12
    • 0345089705 scopus 로고
    • Analytical methodology for the study of metabolites
    • Mitchell, J. R. & Horning, M. G., eds., Raven Press, New York, NY
    • Horning, M. G., Sheng, L.-S. & Lertratanangkoon, K. (1984) Analytical methodology for the study of metabolites. In: Drug Metabolism and Drug Toxicity (Mitchell, J. R. & Horning, M. G., eds.), pp. 353-381. Raven Press, New York, NY.
    • (1984) Drug Metabolism and Drug Toxicity , pp. 353-381
    • Horning, M.G.1    Sheng, L.-S.2    Lertratanangkoon, K.3
  • 13
    • 0016151122 scopus 로고
    • Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite
    • Jollow, D. J., Mitchell, J. R., Zampaglione, N. & Gillette, J. R. (1974) Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite. Pharmacology 11: 151-169.
    • (1974) Pharmacology , vol.11 , pp. 151-169
    • Jollow, D.J.1    Mitchell, J.R.2    Zampaglione, N.3    Gillette, J.R.4
  • 14
    • 0026561930 scopus 로고
    • Glutathione in foods listed in the National Cancer Institute's Health habits and history food frequency questionnaire
    • Jones, D. P., Coates, R. J., Flagg, E. W., Eley, J. W., Block, G., Greenberg, R. S., Gunter, E. W. & Jackson, B. (1992) Glutathione in foods listed in the National Cancer Institute's Health habits and history food frequency questionnaire. Nutr. Cancer 17: 57-75.
    • (1992) Nutr. Cancer , vol.17 , pp. 57-75
    • Jones, D.P.1    Coates, R.J.2    Flagg, E.W.3    Eley, J.W.4    Block, G.5    Greenberg, R.S.6    Gunter, E.W.7    Jackson, B.8
  • 15
    • 0029086183 scopus 로고
    • In vivo modification of 3'-phosphoadenosine-5'-phosphosulfate and sulfate by infusion of sodium sulfate, cysteine, and methionine
    • Kim, H. J., Madhu, C., Cho, J. H. & Klaassen, C. D. (1995) In vivo modification of 3'-phosphoadenosine-5'-phosphosulfate and sulfate by infusion of sodium sulfate, cysteine, and methionine. Drug Metab. Dispos. 23: 840-845.
    • (1995) Drug Metab. Dispos. , vol.23 , pp. 840-845
    • Kim, H.J.1    Madhu, C.2    Cho, J.H.3    Klaassen, C.D.4
  • 16
    • 0027448860 scopus 로고
    • O- and S-methylated bromothiocatechols
    • Lertratanangkoon, K. (1993) O- and S-Methylated bromothiocatechols. Toxicol. Appl. Pharmacol. 122: 200-207.
    • (1993) Toxicol. Appl. Pharmacol. , vol.122 , pp. 200-207
    • Lertratanangkoon, K.1
  • 17
    • 0027195717 scopus 로고
    • Formation of phenol and thiocatechol metabolites from bromobenzene premercapturic acids through pyridoxal phosphate-dependent C-S lyase activity
    • Lertratanangkoon, K. & Denney, D. (1993) Formation of phenol and thiocatechol metabolites from bromobenzene premercapturic acids through pyridoxal phosphate-dependent C-S lyase activity. Biochem. Pharmacol. 45: 2513-2525.
    • (1993) Biochem. Pharmacol. , vol.45 , pp. 2513-2525
    • Lertratanangkoon, K.1    Denney, D.2
  • 18
    • 0023110640 scopus 로고
    • Bromobenzene metabolism in the rat and guinea pig
    • Lertratanangkoon, K. & Horning, M. G. (1987) Bromobenzene metabolism in the rat and guinea pig. Drug Metab. Dispos. 15: 1-11.
    • (1987) Drug Metab. Dispos. , vol.15 , pp. 1-11
    • Lertratanangkoon, K.1    Horning, M.G.2
  • 19
    • 0027207291 scopus 로고
    • Pathways of formation of 2-, 3- and 4-bromophenol from bromobenzene. Proposed mechanism for C-S lyase reactions of cysteine conjugates
    • Lertratanangkoon, K., Horning, E. C. & Horning, M. G. (1993) Pathways of formation of 2-, 3- and 4-bromophenol from bromobenzene. Proposed mechanism for C-S lyase reactions of cysteine conjugates. Res. Commun. Chem. Pathol. Pharmacol. 80: 259-282.
    • (1993) Res. Commun. Chem. Pathol. Pharmacol. , vol.80 , pp. 259-282
    • Lertratanangkoon, K.1    Horning, E.C.2    Horning, M.G.3
  • 20
    • 0030065081 scopus 로고    scopus 로고
    • Methyldonor deficiency due to chemically induced glutathione depletion
    • Lertratanangkoon, K., Orkiszewski, R. S. & Scimeca, J. M. (1996) Methyldonor deficiency due to chemically induced glutathione depletion. Cancer Res. 56: 995-1005.
    • (1996) Cancer Res. , vol.56 , pp. 995-1005
    • Lertratanangkoon, K.1    Orkiszewski, R.S.2    Scimeca, J.M.3
  • 21
    • 0343212247 scopus 로고    scopus 로고
    • Alterations of DNA methylation by acetaminophen
    • abs.
    • Lertratanangkoon, K. & Savaraj, N. (1997) Alterations of DNA methylation by acetaminophen. Fundam. Appl. Toxicol. 36S: 96 (abs.).
    • (1997) Fundam. Appl. Toxicol. , vol.36 S , pp. 96
    • Lertratanangkoon, K.1    Savaraj, N.2
  • 23
    • 0027362756 scopus 로고
    • Prevention of bromobenzene toxicity by N-acetylmethionine: Correlation between toxicity and the impairment in O- and S-methylation of bromothiocatechols
    • Lertratanangkoon, K. & Scimeca, J. M. (1993) Prevention of bromobenzene toxicity by N-acetylmethionine: correlation between toxicity and the impairment in O- and S-methylation of bromothiocatechols. Toxicol. Appl. Pharmacol. 122: 191-199.
    • (1993) Toxicol. Appl. Pharmacol. , vol.122 , pp. 191-199
    • Lertratanangkoon, K.1    Scimeca, J.M.2
  • 24
    • 0030696188 scopus 로고    scopus 로고
    • Alterations of DNA methylation by glutathione depletion
    • Lertratanangkoon, K., Wu, C. J., Savaraj, N. & Thomas, M. L. (1997b) Alterations of DNA methylation by glutathione depletion. Cancer Lett. 120: 149-156.
    • (1997) Cancer Lett. , vol.120 , pp. 149-156
    • Lertratanangkoon, K.1    Wu, C.J.2    Savaraj, N.3    Thomas, M.L.4
  • 25
    • 0016435215 scopus 로고
    • Active site-directed inactivation of cystathionine γ-ynthetase and glutamic pyruvic transaminase by propargylglycine
    • Marcotte, P. & Walsh, C. (1975) Active site-directed inactivation of cystathionine γ-ynthetase and glutamic pyruvic transaminase by propargylglycine. Biochem. Biophys. Res. Commun. 62: 677-682.
    • (1975) Biochem. Biophys. Res. Commun. , vol.62 , pp. 677-682
    • Marcotte, P.1    Walsh, C.2
  • 26
    • 0030920140 scopus 로고    scopus 로고
    • S-adenosylmethionine synthesis: Molecular mechanism and clinical implications
    • Mato, J. M., Alvarez, L., Ortiz, P. & Pajares, M. A. (1997) S-Adenosylmethionine synthesis: molecular mechanism and clinical implications. Pharmacol. Ther. 73: 265-280.
    • (1997) Pharmacol. Ther. , vol.73 , pp. 265-280
    • Mato, J.M.1    Alvarez, L.2    Ortiz, P.3    Pajares, M.A.4
  • 27
    • 0018934312 scopus 로고
    • Labile methyl group balances in the human: The role of sarcosine
    • Mudd, S. H., Ebert, M. H. & Scriver, C. R. (1980) Labile methyl group balances in the human: the role of sarcosine. Metabolism 29: 707-720.
    • (1980) Metabolism , vol.29 , pp. 707-720
    • Mudd, S.H.1    Ebert, M.H.2    Scriver, C.R.3
  • 28
    • 0016722112 scopus 로고
    • Labile methyl balances for normal humans on various dietary regimens
    • Mudd, S. H. & Poole, J. R. (1975) Labile methyl balances for normal humans on various dietary regimens. Metabolism 24: 721-735.
    • (1975) Metabolism , vol.24 , pp. 721-735
    • Mudd, S.H.1    Poole, J.R.2
  • 29
    • 0025357547 scopus 로고
    • Role of the transsulfuration pathway and of γ-cystathionase activity in the formation of cysteine and sulfate from methionine in rat hepatocytes
    • Rao, A. M., Drake, M. R. & Stipanuk, M. H. (1990) Role of the transsulfuration pathway and of γ-cystathionase activity in the formation of cysteine and sulfate from methionine in rat hepatocytes. J. Nutr. 120: 837-845.
    • (1990) J. Nutr. , vol.120 , pp. 837-845
    • Rao, A.M.1    Drake, M.R.2    Stipanuk, M.H.3
  • 30
    • 0029174789 scopus 로고
    • Cystathionine
    • Reed, D. J. (1995) Cystathionine. Methods Enzymol. 252: 92-102.
    • (1995) Methods Enzymol. , vol.252 , pp. 92-102
    • Reed, D.J.1
  • 31
    • 0017753701 scopus 로고
    • The role of methionine in glutathione biosynthesis by isolated hepatocytes
    • Reed, D. J. & Orrenius, S. (1977) The role of methionine in glutathione biosynthesis by isolated hepatocytes. Biochem. Biophys. Res. Commun. 77: 1257-1264.
    • (1977) Biochem. Biophys. Res. Commun. , vol.77 , pp. 1257-1264
    • Reed, D.J.1    Orrenius, S.2
  • 32
    • 0022979951 scopus 로고
    • A purified cysteine conjugate β-lyase from rat kidney cytosol. Requirement for an α-keto acid or an amino acid oxidase for activity and identity with soluble glutamine transaminase K
    • Stevens, J., Robbins, J. D. & Byrd, R. A. (1986) A purified cysteine conjugate β-lyase from rat kidney cytosol. Requirement for an α-keto acid or an amino acid oxidase for activity and identity with soluble glutamine transaminase K. J. Biol. Chem. 261: 15529-15537.
    • (1986) J. Biol. Chem. , vol.261 , pp. 15529-15537
    • Stevens, J.1    Robbins, J.D.2    Byrd, R.A.3
  • 33
    • 0026537224 scopus 로고
    • Cysteine concentration regulates cysteine metabolism to glutathione, sulfate and taurine in rat hepatocytes
    • Stipanuk, M. H., Coloso, R. M., Garcia, R.A.G. & Banks, M. F. (1992) Cysteine concentration regulates cysteine metabolism to glutathione, sulfate and taurine in rat hepatocytes. J. Nutr. 122: 420-427.
    • (1992) J. Nutr. , vol.122 , pp. 420-427
    • Stipanuk, M.H.1    Coloso, R.M.2    Garcia, R.A.G.3    Banks, M.F.4
  • 34
    • 0017227839 scopus 로고
    • Irreversible inactivation of aspartate aminotransferases during transamination with L-propargylglycine
    • Tanase, S. & Morino, Y. (1976) Irreversible inactivation of aspartate aminotransferases during transamination with L-propargylglycine. Biochem. Biophys. Res. Commun. 68: 1301-1308.
    • (1976) Biochem. Biophys. Res. Commun. , vol.68 , pp. 1301-1308
    • Tanase, S.1    Morino, Y.2
  • 35
    • 0002760470 scopus 로고
    • Acquired resistance of tumor cells to L-phenylalanine mustard: Implications for the design of a clinical trial involving glutathione depletion
    • Taniguchi, N., Higashi, T., Sakamoto, Y. & Meister, A., eds., Academic Press, New York, NY
    • Vistica, D. T. & Ahmad, S. (1989) Acquired resistance of tumor cells to L-phenylalanine mustard: implications for the design of a clinical trial involving glutathione depletion. In: Glutathione Centennial Molecular Perspectives and Clinical Implications (Taniguchi, N., Higashi, T., Sakamoto, Y. & Meister, A., eds.), pp. 301-315. Academic Press, New York, NY.
    • (1989) Glutathione Centennial Molecular Perspectives and Clinical Implications , pp. 301-315
    • Vistica, D.T.1    Ahmad, S.2
  • 36
    • 0000266418 scopus 로고
    • The partial replacement of dietary methionine by cystine for purposes of growth
    • Womack, M. & Rose, W. (1941) The partial replacement of dietary methionine by cystine for purposes of growth. J. Biol. Chem. 141: 375-379.
    • (1941) J. Biol. Chem. , vol.141 , pp. 375-379
    • Womack, M.1    Rose, W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.