Three cases of congenital growth hormone deficiency with micropenis and hypospadias: What does growth hormone have to do with it?

Hormone Research

Volumn 51, Issue 2, 1999, Pages 101-104

  Velasquez Urzola, Alejandro ^a   Leger, Juliane ^a   Czernichow, Paul ^a  

^a HÔPITAL ROBERT DEBRÉ   (France)

Author keywords

Growth hormone deficiency; Male pseudohermaphroditism; Micropenis

Indexed keywords

GONADOTROPIN; GROWTH HORMONE; TESTOSTERONE;

ADENOHYPOPHYSIS; AGENESIS; ARTICLE; CASE REPORT; CORPUS CALLOSUM; GROWTH HORMONE DEFICIENCY; HUMAN; HYPOSPADIAS; KARYOTYPE; MALE; MALE PSEUDOHERMAPHRODITISM; MICROPENIS; MUELLERIAN DUCT; NEWBORN; PRESCHOOL CHILD; PRIORITY JOURNAL; SEX DIFFERENTIATION; ULTRASOUND; UROGENITAL TRACT RADIOGRAPHY;

FETAL GROWTH RETARDATION; HUMAN GROWTH HORMONE; HUMANS; HYPOSPADIAS; INFANT, NEWBORN; INFANT, SMALL FOR GESTATIONAL AGE; MALE; PENILE DISEASES; PENIS; PITUITARY GLAND, ANTERIOR; TESTOSTERONE;

EID: 0032979655     PISSN: 03010163     EISSN: None     Source Type: Journal    
DOI: 10.1159/000023324     Document Type: Article

References (11)

1. Siiteri PK, Wilson JD: Testosterone formation and metabolism during male sexual differentiation in the human embryo. J Clin Endocrinol Metab 1974;38:113-117.
2. Saenger P: Abnormal sex differentiation. J Pediatr 1984;104:1-14.
3. Sadeghi-Nejad A, Senior B: A familial syndrome of isolated 'aplasia' of the anterior pituitary. Diagnostic studies and treatment in the neonatal period. J Pediatr 1974;84:79-84.
4. Cacciari E, Cicognani A, Pirazzoli P, Tassoni F, Bernardi S, Salardi F, Zappulla L, Mazzanti L: Congenital hypopituitarism associated with neonatal hypoglycemia and microphallus: Effect of GH therapy. Helv Paediatr Acta 1976; 31:481-485.
5. Burgner DP, Kinmond S, Wallace AM, Young DG, Forest MG, Donaldson MDC: Male pseudohermaphroditism secondary to panhypopituitarism. Arch Dis Child 1996;75:153-155.
6. Albers N, Ulrichs C, Glüer S, Hiort O, Sinnecker GHG, Mildenberger H, Brodehl J: Etiologic classification of severe hypospadias: Implications for prognosis and management. J Pediatr 1997;131:386-392.
7. Laron Z, Sanel R: Penis and testicular size in patients with growth hormone insufficiency. Acta Endocrinol 1970;63:625-633.
8. Laron Z, Klinger B: Effect of insulin-like growth factor-1 treatment on serum androgens and testicular and penile size in males with Laron syndrome (primary growth hormone resistance). Eur J Endocrinol 1998;138:176-180.
9. Nguyen AP, Chandorkar A, Gupta C: The role of growth hormone in fetal mouse reproductive tract differentiation. Endocrinology 1996;137: 3659-3666.
10. Schonfeld WA, Beebe GW: Normal growth and variation in the male genitalia from birth to maturity. J Urol 1942;48:759-777.
11. Feldman KW, Smith DW: Fetal phallic growth and penile standards for mewborn male infants. J Pediatr 1975;86:395-398.