Induction of selected lipid metabolic enzymes and differentiation- linked structural proteins by air exposure in fetal rat skin explants

Journal of Investigative Dermatology

Volumn 112, Issue 3, 1999, Pages 303-309

  Kömüves, László G ^a,b   Hanley, Karen ^a,b   Jiang, Yan ^a   Katagiri, Chika ^a,c   Elias, Peter M ^a,b   Williams, Mary L ^a,b   Feingold, Kenneth R ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Department of Biostatistics   (United States)

^c SHISEIDO RESEARCH CENTER   (Japan)

Author keywords

Filaggrin; Involucrin; Loricrin; Steroid sulfatase; Stratum corneum; Glucocerebrosidase

Indexed keywords

CERAMIDE; CHOLESTEROL SULFATE; FILAGGRIN; GLUCOSYLCERAMIDASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; INVOLUCRIN; LORICRIN; MESSENGER RNA; STERYL SULFATASE;

ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; ENZYME ACTIVITY; EPIDERMIS CELL; IMMUNOHISTOCHEMISTRY; LIPID METABOLISM; NONHUMAN; ONTOGENY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SKIN; SKIN PERMEABILITY; STRATUM CORNEUM;

EID: 0032979048     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.1999.00511.x     Document Type: Article

References (33)

1. Bickenbach JR, Green JM, Bundman BS, Rothnagel JA, Roop DR: Loricrin expression is coordinated with other epidermal proteins and the appearance of lipid lamellar granules in development. J Invest Dermatol 104:405-410, 1995
2. Cartlidge PHT, Rutter N. Skin barrier function. In: Polin RA, Fox WW (eds). Fetal and Neonatal Physiology, 2nd edn. Philadelphia: WB Sanders, 1998, pp. 771-788
3. Chujor CSN, Holleran WM, Feingold KR, Elias PM: Glucosylceramide synthase activity in murine epidermis: Quantitation, localization, regulation, and requirement for barrier homeostasis. J Lipid Res 39:277-288, 1998
4. Downing DT: Lipid and protein structures in the permeability barrier of mammalian epidermis. J Lipid Res 33:301-313, 1992
5. Elias PM, Menon GK: Structural and lipid biochemical correlates of the epidermal permeability barrier. Adv Lipid Res 24:1-26, 1991
6. Elias PM, Williams ML, Maloney ME, Bonifas JA, Brown BE, Grayson S, Epstein EH Jr: Stratum corneum lipids in disorders of cornification: Steroid sulfatase and cholesterol sulfate in normal desquamation and the pathogenesis of recessive X-linked ichthyosis. J Clin Invest 74:1414-1421, 1984
7. Elias PM, Nau P, Hanley K, et al: Formation of the epidermal calcium gradient coincides with key milestones of barrier ontogenesis in the rodent. J Invest Dermatol 110:399-404, 1998
8. Epstein EH Jr, Williams ML, Elias PM: Steroid sulfatase, X-linked icthyosis, and stratum corneum cell cohesion. Arch Dermatol 117:761-763, 1981
9. Evans NJ, Rutter N: Development of the epidermis in the newborn. Biol Neonate 49:74-80, 1986
10. Fartasch M, Ponec M: Improved barrier structure formation in air-exposed human keratinocyte culture systems. J Invest Dermatol 102:366-374, 1994
11. Feingold KR: The regulation and role of epidermal lipid synthesis. Adv Lipid Res 24:57-82, 1991
12. Feingold KR, Man MQ, Menon GK, Cho SS, Brown BE, Elias PM: Cholesterol synthesis is required for cutaneous barrier function in mice. J Clin Invest 86:1738-1745, 1990
13. Fuchs E: Epidermal differentiation: the bare essentials. J Cell Biol 111:2807-2814, 1990
14. Grubauer G, Elias PM, Feingold KR: Transepidermal water loss: The signal for recovery of barrier structure and function. J Lipid Res 30:323-333, 1989
15. Hanley K, Rassner U, Elias PM, Williams ML, Feingold KR: Epidermal barrier ontogenesis: maturation in serum-free media and acceleration by glucocorticoids and thyroid hormone but not selected growth factors. J Invest Dermatol 106:404-411, 1996
16. Hanley K, Jiang Y, Elias PM, Feingold KR, Williams ML: Acceleration of barrier ontogenesis in vitro through air exposure. Pediatr Res 41:293-299, 1997a
17. Hanley K, Jiang Y, Holleran WM, Elias PM, Williams ML, Feingold KR: Glucosylceramide metabolism is regulated during normal and hormonally stimulated epidermal barrier development in the rat. J Lipid Res 38:576-584, 1997b
18. Hanley K, Jiang Y, Katagiri C, Feingold KR, Williams ML: Epidermal steroid sulfatase and cholesterol sulfotransferase are regulated during late gestation in the fetal rat. J Invest Dermatol 108:871-875, 1997c
19. Harpin VA, Rutter N: Barrier properties of newborn infant's skin. J Pediatr 102:419-425, 1983
20. Holleran WM, Feingold KR, Man M-Q, Gao WN, Lee JM, Elias PM: Regulation of epidermal sphingolipid synthesis by permeability barrier function. J Lipid Res 32:1151-1158, 1991a
21. Holleran WM, Man MQ, Gao WN, Menon GK, Elias PM, Feingold KR: Sphingolipids are required for mammalian epidermal barrier function. Inhibition of sphingolipid synthesis delays barrier recovery after acute perturbation. J Clin Invest 88:1338-1345, 1991b
22. Holleran WM, Takagi Y, Imokawa G, Jackson S, Lee JM, Elias PM: γ-Glucocerebrosidase activity in murine epidermis: Characterization and localization in relationship to differentiation. J Lipid Res 33:1201-1209, 1992
23. Holleran WM, Takagi Y, Menon GK, Legler G, Feingold KR, Elias PM: Processing of epidermal glucosylceramides is required for optimal mammalian cutaneous permeability barrier function. J Clin Invest 91:1656-1664, 1993
24. Holleran WM, Ginns El, Menon GK, et al: Consequences of beta-glucocerebrosidase deficiency in epidermis. Ultrastructural and permeability barrier alterations in gaucher disease. J Clin Invest 93:1756-1764, 1995
25. Holleran WM, Takagi Y, Menon GK, Jackson SM, Lee JM, Feingold KR, Elias PM: Permeability barrier requirements regulate epidermal β-glucocerebrosidase. J Lipid Res 35:905-912, 1994
26. Hurt K, Hanley K, Williams ML, Feingold KR: Cutaneous lipid synthesis during late fetal development in the rat. Arch Dermat Res 287:754-760, 1995
27. Kömüves LG, Hanley K, Jiang Y, Elias PM, Willaims ML, Feingold KR: Ligands and activators of nuclear hormone receptors regulate epidermal differentiation during fetal rat skin development. J Invest Dermatol 111:429-433, 1998
28. Lee SH, Elias PM, Proksch E, Menon GM, Mao-Quiang M, Feingold KR: Calcium and potassium are important regulators of barrier homeostasis in murine epidermis. J Clin Invest 89 (2):530-538, 1992
29. Proksch E, Holleran WM, Menon GK, Elias PM, Feingold KR: Barrier function regulates epidermal lipid synthesis and DNA synthesis. Br J Dermatol 128:473-482, 1993
30. Rosdy M, Clauss L-C: Terminal differentiation of human keratinocytes grown in chemically-defined medium on inert filter substrates at the air-liquid interface. J Invest Dermatol 95:409-414, 1990
31. Williams ML, Elias PM: Stratum corneum lipids in disorders of cornification. J Clin Invest 68:1404-1410, 1981
32. Williams ML, Brown BE, Monger DJ, Grayson S, Elias PM: Lipid content and metabolism of human keratinocyte cultures grown at the air-medium interface. J Cell Physiol 136:103-110, 1988
33. Zettersten E, Man MQ, Sato M, et al: Recessive X-linked ichthyosis: Role of cholesterol sulfate accumulation in the barrier abnormality. J Invest Dermatol 111:784-790, 1998