An important role for major histocompatibility complex class I- restricted T cells, and a limited role for gamma interferon, in protection of mice against lethal herpes simplex virus infection

Journal of Virology

Volumn 73, Issue 3, 1999, Pages 2058-2063

  Holterman, Ai Xuan ^a,d   Rogers, Kathleen ^a   Edelmann, Kurt ^b   Koelle, David M ^b,c   Corey, Lawrence ^b,c   Wilson, Christopher B ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c Fred Hutchinson Cancer Research Center   (United States)

^d UNIVERSITY OF ILLINOIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELLULAR IMMUNITY; CYTOKINE PRODUCTION; HERPES SIMPLEX; HERPES SIMPLEX VIRUS; KNOCKOUT GENE; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; VIRUS IMMUNITY;

EID: 0032978605     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.3.2058-2063.1999     Document Type: Article

References (44)

1. Ahn, K., T. H. Meyer, S. Cebel, P. Semp'e, H. Djaballah, Y. Yang, P. A. Peterson, K. Fruh, and R. Tamp'e. 1996. Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus ICP47. EMBO J. 15: 3247-3255.
2. Bendelac, A., M. N. Rivera, S. H. Park, and J. H. Roark. 1997. Mouse GD1-specific NK1 T cells: development, specificity and function. Annu. Rev. Immunol. 15:535-562.
3. Bonneau, R. H., L. A. Salvucci, D. C. Johnson, and S. S. Tevethia. 1993. Epitope specificity of H-2Kb-restricted, HSV-1-, and HSV-2-cross-reactive cytotoxic T lymphocyte clones. Virology 195:62-70.
4. Bouley, D. M., S. Kanangat, W. Wire, and B. T. Rouse. 1995. Characterization of herpes simplex virus type-1 infection and herpetic stromal keratitis development in IFN-gamma knockout mice J. Immunol. 155:3964-3971.
5. Cantin, E. M., D. R. Hinton, J. Chen, and H. Openshaw. 1995. Gamma interferon expression during acute and latent nervous system infection by herpes simplex virus type 1. J. Virol. 69:4898-4905.
6. Cook, M. L., and J. G. Stevens. 1973. Pathogenesis of herpetic neuritis and ganglionitis in mice: evidence for intra-axonal transport of infection. Infect. Immun. 7:272-288.
7. Cook, M. L., and J. G. Stevens. 1983. Restricted replication of herpes simplex virus in spinal ganglia of resistant mice is accompanied by an early infiltration of immunoglobulin G-bearing cells. Infect. Immun. 40:752-758.
8. Cose, S. C., J. M. Kelly, and F. R. Carbone. 1995. Characterization of a diverse primary herpes simplex virus type 1 gB-specific cytotoxic T-cell response showing a preferential Vβ bias. J. Virol. 69:5849-5852.
9. Feduchi, E., M. A. Alonso, and L. Carrasco. 1989. Human gamma Interferon and tumor necrosis factor exert a synergistic blockade on the replication of herpes simplex virus. J. Virol. 63:1354-1359.
10. Geiger, K. D., D. Gurushanthaiah, E. L. Howes, G. A. Lewandowski, J. C. Reed, F. E. Bloom, and N. E. Sarvetnick. 1995. Cytokine-mediated survival from lethal herpes simplex virus infection: role of programmed neuronal death. Proc. Natl. Acad. Sci. USA 92:3411-3415.
11. Gold, R., K. V. Toyka, and H. P. Hartung. 1995. Synergistic effect of IFN-gamma and TNF-alpha on expression of immune molecules and antigen presentation by Schwann cells. Cell. Immunol. 165:65-70.
12. Goldsmith, K., W. Chen, D. C. Johnson, and R. L. Hendricks. 1998. Infected cell protein (ICP)47 enhances herpes simplex virus neurovirulence by blocking the CDS+ T cell response. J. Exp. Med. 187:341-348.
13. Halford, W. P., B. M. Gebhardt, and D. J. J. Carr. 1996. Persistent cytokine expression in trigeminal ganglion latently infected with herpes simplex virus type 1. J. Immunol. 157:3542-3549.
14. Hill, A., P. Jugovic, I. York, G. Russ, J. Bennink, J. Yewdell, H. Ploegh, and D. Johnson. 1995. Herpes simplex virus turns off the TAP to evade host immunity. Nature 375:411-415.
15. Kay, M. A., A. X. Holterman, L. Meuse, A. Gown, H. D. Ochs, P. S. Linsley, and C. B. Wilson. 1995. Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4Ig administration. Nat. Genet. 11:191-197.
16. Koelle, D. M., C. M. Posavad, G. R. Barnum, M. L. Johnson, J. M. Frank, and L. Corey. 1998. Clearance of HSV-2 from recurrent genital lesions correlates with infiltration of HSV-specific cytotoxic T lymphocytes. J. Clin. Investig. 101:1500-1508.
17. Koller, B. H., P. Marrack, J. W. Kappler, and O. Smithies. 1990. Normal development of mice deficient in Beta2M, MHC class I proteins, and CD8+ T cells. Science 248:1227-1230.
18. Lewandowski, G. A., D. Lo, and F. E. Bloom. 1993. Interference with major histocompatibility complex class II-restricted antigen presentation in the brain by herpes simplex virus type 1: a possible mechanism of evasion of the immune response. Proc. Natl. Acad. Sci. USA 90:2005-2009.
19. Liu, T., Q. Tang, and R. L. Hendricks. 1996 Inflammatory infiltration of the trigeminal ganglion after herpes simplex virus type 1 corneal infection. J. Virol. 70:264-271.
20. Manickan, E., and B. T. Rouse. 1995. Roles of different T-cell subsets in control of herpes simplex virus infection determined by using T-cell-deficient mouse models. J. Virol. 69:8178-8179.
21. Mercadal, C. M., S. Martin, and B. T. Rouse. 1991. Apparent requirement for CD4+ T cells in primary anti-herpes simplex virus cytotoxic T-lymphocyte induction can be overcome by optimal antigen presentation. Viral Immunol. 4:177-186.
22. Mikloska, Z., A. M. Kesson, M. E. T. Penfold, and A. L. Cunningham. 1996. Herpes simplex virus protein targets for CD4 and CD8 lymphocyte cytotoxicity in cultured epidermal keratinocytes treated with interferon-gamma. J. Infect. Dis. 173:7-17.
23. Milligan, G. N., and D. I. Bernstein. 1995. Analysis of herpes simplex virus-specific T cells in the murine female genital tract following infection with herpes simplex virus type 2. Virology 212:481-489.
24. Milligan, G. N., and D. I. Bernstein. 1997 Interferon-gamma enhances resolution of herpes simplex virus type 2 infection of the murine genital tract. Virology 229:259-268.
25. Milligan, G. N., D. I. Bernstein, and N. Bourne. 1998. T lymphocytes are required for protection of the vaginal mucosae and sensory ganglia of immune mice against reinfection with herpes simplex virus type 2. J. Immunol. 160:6093-6100.
26. Nash, A. A., A. Jayasuriya. J. Phelan, S. P. Cobbold, H. Waldmann, and T. Prospero. 1987. Different roles for L3T4+ and Lyt 2+ T cell subsets in the control of an acute herpes simplex virus infection of the skin and nervous system. J. Gen. Virol. 68:825-833.
27. Nguyen, L., D. M. Knipe, and R. W. Finberg. 1994. Mechanism of virus-induced Ig subclass shifts. J. Immunol. 152:478-484.
28. Niemialtowski, M. G., V. L. Godfrey, and B. T. Rouse. 1994. Quantitative studies on CD4+ and CD8+ cytotoxic T lymphocyte responses against herpes simplex virus type 1 in normal and beta 2-m deficient mice. Immunobiology 190:183-194.
29. Paul, W. E., and R. A. Seder. 1994. Lymphocyte responses and cytokines. Cell 76:241-251.
30. Peschon, J., D. Dauphine, K. Stocking, M. Glaccum, C. Otten, C. Willis, K. Charrier, P. Morissey, C. Ware, and K. Mohler. 1998. TNF receptor-deficient mice reveal divergent roles for p55 and p75 in several models of inflammation. J. Immunol. 160:943-952.
31. Posavad, C. M., D. M. Koelle, and L. Corey. 1998. Tipping the scales of herpes simplex virus reactivation: the important responses are local. Nat. Med. 4:381-382.
32. Posavad, C. M., D. M. Koelle, M. F. Shaughnessy, and L. Corey. 1997. Severe genital herpes infections in HIV-infected individuals with impaired herpes simplex virus-specific CD8+ cytotoxic T lymphocyte responses. Proc. Natl. Acad. Sci. USA 94:10289-10294.
33. Raulet, D. H. 1994. MHC class I-deficient mice. Adv. Immunol. 55:381-421.
34. Schmid, D. S, and B. T. Rouse. 1992. The role of T cell immunity in control of herpes simplex virus. Curr. Top. Microbiol. Immunol. 179:57-74.
35. Simmons, A., D. Tscharke, and P. Speck. 1992. The role of immune mechanisms in control of herpes simplex virus infection of the peripheral nervous system. Curr. Top. Microbiol. Immunol. 179:31-56.
36. Simmons, A., and D. C. Tscharke. 1992. Anti-CD8 impairs clearance of herpes simplex virus from the nervous system: implications for the fate of virally infected neurons. J. Exp. Med. 175:1337-1344.
37. Smith, P. M., R. M. Wolcott, R. Chervenak, and S. R. Jennings. 1994. Control of acute cutaneous herpes simplex virus infection: T cell-mediated viral clearance is dependent upon interferon-gamma (IFN-gamma). Virology 202:76-88.
38. Stohlman, S. A., C. C. Bergmann, M. T. Lin, D. J. Cua, and D. R. Hinton. 1998. CTL effector function within the central nervous system requires CD4+ T cells. J. Immunol. 160:2896-2904.
39. Strelow, L. I., and D. A. Leib. 1995. Role of the virion host shutoff (vhs) of herpes simplex virus type 1 in latency and pathogenesis. J. Virol. 69:6779-6786.
40. Tay, C. H., R. M. Welsh, and R. R. Brutkiewicz. 1995. NK cell response to viral infections in beta 2-microglobulin-deficient mice. J. Immunol. 154:780-789.
41. Tigges, M. A., S. Leng, D. C. Johnson, and R. L. Burke. 1996. Human herpes simplex virus (HSV)-specific CD8+ CTL clones recognize HSV-2-infected fibroblasts after treatment with IFN-gamma or when virion host shutoff functions are disabled. J. Immunol. 156:3901-3910.
42. Tomazin, R., N. E. van School, K. Goldsmith, P. Jugovic, P. Semp'e, K. Fruh, and D. C. Johnson. 1998. Herpes simplex virus type 2 ICP47 inhibits human TAP but not mouse TAP. J. Virol. 72:2560-2563.
43. York, I. A., C. Roop, D. W. Andrews, S. R. Riddell, F. L. Graham, and D. C. Johnson. 1994. A cytosolic herpes simplex virus protein inhibits antigen presentation to CD8+ T lymphocytes. Cell 77:525-535.
44. Yu, Z., E. Manickan, and B. T. Rouse. 1996. Role of interferon-gamma in immunity to herpes simplex virus. J. Leukoc. Biol. 60:528-532.