Thujone exhibits low affinity for cannabinoid receptors but fails to evoke cannabimimetic responses

Pharmacology Biochemistry and Behavior

Volumn 62, Issue 3, 1999, Pages 473-480

  Meschler, Justin P ^a   Howlett, Allyn C ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Absinthe; Adenylate cyclase; Antinociception; Cannabinoids; CB1 cannabinoid receptors; G proteins; Levonantradol; Marijuana; Motor activity; Oil of wormwood; Thujone

Indexed keywords

4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; ABSINTHOL; ADENYLATE CYCLASE; ARTEMISIA ABSINTHIUM EXTRACT; CANNABINOID RECEPTOR; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); LEVONANTRADOL; PLANT EXTRACT; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN MEMBRANE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TONSIL;

ADENYLATE CYCLASE; ANIMALS; ARTEMISIA; BEHAVIOR, ANIMAL; BINDING, COMPETITIVE; BRAIN CHEMISTRY; CANNABINOIDS; CYCLOHEXANOLS; FORSKOLIN; GTP-BINDING PROTEINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; MALE; MONOTERPENES; PLANTS, MEDICINAL; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, CANNABINOID, CB2; RECEPTORS, CANNABINOID; RECEPTORS, DRUG; SIGNAL TRANSDUCTION; TERPENES; TONSIL;

EID: 0032977925     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(98)00195-6     Document Type: Article

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