Immunohistochemical detection of cytotoxic lymphocytes in malignant serous effusions

Diagnostic Cytopathology

Volumn 21, Issue 1, 1999, Pages 18-21

  Yu, Gordon H ^a   Hida, Catherine A ^a   Salhany, Kevin E ^a   Baloch, Zubair ^a   Gupta, Prabodh K ^a  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Adenocarcinoma; Cytotoxic lymphocytes; Cytotoxic T cells; Natural killer cells; Serous effusions; TIA 1

Indexed keywords

LYMPHOCYTE ANTIGEN;

ADENOCARCINOMA; ANTIGEN EXPRESSION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; EFFUSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; NATURAL KILLER CELL; PRIORITY JOURNAL; RELIABILITY;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD; ANTIGENS, CD3; ANTIGENS, CD43; ANTIGENS, CD79; ASCITIC FLUID; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE PROTEINS; MIDDLE AGED; PERICARDIAL EFFUSION; PLEURAL EFFUSION, MALIGNANT; POLY(A)-BINDING PROTEINS; PROTEINS; RECEPTORS, ANTIGEN, B-CELL; RNA-BINDING PROTEINS; SIALOGLYCOPROTEINS; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0032977377     PISSN: 87551039     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0339(199907)21:1<18::AID-DC6>3.0.CO;2-G     Document Type: Article

References (28)

1. Mason MR, Bedrossian CWM, Fahey CA. Value of immunocytochemistry in the study of malignant effusions. Diagn Cytopathol 1987;3:215-221.
2. Silverman JF, Nance K, Philips B, Norris HT. The use of immunoperoxidase panels for the cytologic diagnosis of malignancy in serous effusions. Diagn Cytopathol 1987;3:134-140.
3. Nance KV, Silverman JF. The utility of ancillary techniques in effusion cytology. Diagn Cytopathol 1992;8:185-189.
4. Croonen JM, van der Valk P, Herman CJ, Lindeman J. Cytology, immunopathology, and flow cytometry in the diagnosis of pleural and peritoneal effusions. Lab Invest 1988;58:725-732.
5. Daste G, Serre G, Mauduyt MA, Vincent C, Caveriviere P, Soleihavoup JP. Immunophenotyping of mesothelial cells and carcinoma cells with monoclonal antibodies to cytokeratins, vimentin, CEA, and EMA improves the cytodiagnosis of serous effusions. Cytopathology 1991;2: 19-28.
6. Estaeban JM, Yokota S, Husain S, Battifora H. Immunocytochemical profile of benign and carcinomatous effusions: a practical approach to difficult diagnosis. Am J Clin Pathol 1990;94:698-705.
7. Maguire B, Whitaker D, Carrello S, Spagnolo D. Monoclonal antibody Ber-EP4: its use in the differential diagnosis of malignant mesothelioma and carcinoma in cell blocks of malignant effusions and FNA specimens. Diagn Cytopathol 1994;10:130-134.
8. Cajulis RS, Frias-Hidvegi D, Yu GH. Eggena S. Detection of numerical chromosomal abnormalities by fluorescence in situ hybridization of interphase cell nuclei with chromosome-specific probes on archival cytologic samples. Diagn Cytopathol 1996;14:178-181.
9. Cajulis RS, Yu GH, Gokaslan ST, Hidvegi DF. Modified interphase cytogenetics technique as an adjunct in the analysis of atypical cells in body fluids. Diagn Cytopathol 1997;16:331-335.
10. Cajulis RS, Frias-Hidvegi D. Detection of numerical chromosomal abnormalities in malignant cells on body fluids by fluorescence in situ hybridization of interphase cell nuclei with chromosome specific probes. Diagn Cytopathol 1992;8:627-631.
11. Herrera GA, Wilkerson JA. Ultrastructural studies of malignant cells in fluids. Diagn Cytopathol 1985;1:272-285.
12. Joseph MG, Banerjee D, Harris P, Gibson S, McFadden RG. Multiparameter flow cytometric DNA analysis of effusions: a prospective study of 36 cases compared with routine cytology and immunohistochemistry. Mod Pathol 1995;8:686-693.
13. Green LK, Griffin J. Increased natural killer cells in fluids: a new. sensitive means of detecting carcinoma. Acta Cytol 1996;40:1240-1245.
14. Fitzgerald-Bocarsly P, Herberman R, Hercend T. et al. A definition of natural killer cells. Immunol Today 1988;9:292.
15. Richards SJ, Scott CS. Human NK cells in health and disease: clinical, functional, phenotypic and DNA genotypic characteristics. Leuk Lymphoma 1992;7:377-399.
16. Jezewska E, Sikora J, Slowik-Gabryelska A, Zeromski J. Evaluation of immunophenotype of lymphoid cells isolated from malignant pleural effusions. Arch Immunol Ther Exp 1993;41:51-56.
17. Oka M, Yoshino S, Hazama S, Shimoda K, Suzuki T. The characterization of peritoneal and pleural exudate cells from malignant effusions. Surg Today 1993;23:500-503.
18. + T lymphocytes. J Immunol 1990;144:574-582.
19. Felgar RE, Macon WR, Kinney MC, Roberts S, Pasha T, Salhany KE. TIA-1 expression in lymphoid neoplasms: identification of subsets with cytotoxic T lymphocyte or natural killer cell differentiation. Am J Pathol 1997;150:1893-1900.
20. Sale GE, Anderson P, Browne M, Myerson D. Evidence of cytotoxic T-cell destruction of epidermal cells in human graft-vs-host disease. Arch Pathol Lab Med 1992;116:622-625.
21. deLajarte AS, Brun P, Baudouin V, Paris R, Loirat C, Peuchmaur M. Detection of TIA-1 cytotoxic T-lymphocytes and epithelial apoptotic cells in renal allograft biopsies. Transplant Proc 1995;27:2474-2475.
22. + lymphocytes in lymph nodes of human immunodeficiency virus-1-infected patients. Am J Pathol 1993;142:1750-1758.
23. + cytotoxic cells are present in increased numbers in the intestinal mucosa from patients with active inflammatory bowel disease. Am J Pathol 1998;152:261-268.
24. Leger-Ravet M, Devergne O, Peuchmaur P, et al. In situ detection of activated cytotoxic cells in follicular lymphomas. Am J Pathol 1994;144: 492-499.
25. Oudejans JJ, Jiwa NM, Kummer JA, et al. Activated cytotoxic T cells as prognostic marker in Hodgkin's disease. Blood 1997;89:1376-1382.
26. Anderson P. TIA-1: structural and functional studies on a new class of cytolytic effector molecule. Curr Top Microbiol Immunol 1995;198: 131-143.
27. Pollard K, Lunny D, Holgate CS, Jackson P, Bird CC. Fixation, processing, and immunochemical reagent effects on preservation of T-lymphocyte surface membrane antigens in paraffin-embedded tissue. J Histochem Cytochem 1987;35:1329-1338.
28. Chan JKC, Tsang WYW, Ng CS, Pau MY. Discordant CD3 expression in lymphomas when studied on frozen and paraffin sections. Hum Pathol 1995;26:1139-1143.