Cellular and molecular bases of axonal regeneration in the fish central nervous system

Experimental Neurology

Volumn 157, Issue 2, 1999, Pages 223-240

  Bernhardt, R R ^a,b  

^a UNIVERSITY OF HAMBURG   (Germany)

^b ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN; NERVE CELL ADHESION MOLECULE; NEUROMODULIN;

ASTROCYTE; CELL SPECIFICITY; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; FISH; MACROPHAGE; NERVE CELL; NERVE FIBER REGENERATION; NONHUMAN; PRIORITY JOURNAL; RETINA GANGLION CELL; REVIEW;

EID: 0032976194     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1999.7059     Document Type: Review

References (204)

1. Aigner L., Arber S., Kapfhammer J. P., Laux T., Schneider C., Botteri F., Brenner H. R., Caroni P. Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice. Cell. 83:1995;269-278.
2. Allcutt D., Berry M., Sievers J. A quantitative comparison of the reactions of retinal ganglion cells to optic nerve crush in neonatal and adult mice. Brain Res. 318:1984;219-230.
3. Ankerhold R., Leppert C. A., Bastmeyer M., Stuermer C. A. O. E567 antigen is upregulated by goldfish oligodendrocytes after optic nerve lesion and supports retinal axon regeneration. Glia. 23:1998;257-270.
4. Appel C., Gloor S., Schmalzing G., Schachner M., Bernhardt R. R. Expression of a Na,K-ATPase beta 3 subunit during development of the zebrafish central nervous system. J. Neurosci. Res. 46:1996;551-564.
5. Attardi D. G., Sperry R. W. Preferential selection of central pathways by regenerating optic fibers. Exp. Neurol. 7:1963;46-64.
6. Baehr M. Target-specific guidance cues for regenerating axons are reexpressed in the lesioned adult mammalian central nervous system. Adv. Neurol. 73:1997;83-90.
7. Baehr M., Bonhoeffer F. Perspectives on axonal regeneration in the mammalian CNS. Trends Neurosci. 17:1994;473-479.
8. Baehr M., Winzenmann A. Retinal ganglion cell axons recognize specific guidance cues present in the deafferented adult rat superior colliculus. J. Neurosci. 16:1996;5106-5116.
9. Barron K. D., McGuiness C. M., Misantone L. J., Zanakis M. F., Grafstein B., Murray M. RNA content of normal and axotomized retinal ganglion cells of rat and goldfish. J. Comp. Neurol. 236:1985;265-273.
10. Bartsch U. The extracellular matrix molecule tenascin-C: Expression in vivo and functional characterization in vitro. Prog. Neurobiol. 49:1996;145-168.
11. Bastmeyer M., Baehr M., Stuermer C. A. Fish optic nerve oligodendrocytes support axonal regeneration of fish and mammalian retinal ganglion cells. Glia. 8:1993;1-11.
12. Bastmeyer M., Beckmann M., Schwab M. E., Stuermer C. A. Growth of regenerating goldfish axons is inhibited by rat oligodendrocytes and CNS myelin but not by goldfish optic nerve tract oligodendrocytelike cells and fish CNS myelin. J. Neurosci. 11:1991;626-640.
13. Bastmeyer M., Jeserich G., Stuermer C. A. Similarities and differences between fish oligodendrocytes and Schwann cells in vitro. Glia. 11:1994;300-314.
14. Bastmeyer M., Ott H., Leppert C. A., Stuermer C. A. Fish E587 glycoprotein, a member of the L1 family of cell adhesion molecules, participates in axonal fasciculation and the age-related order of ganglion cell axons in the goldfish retina. J. Cell Biol. 130:1995;969-976.
15. Bastmeyer M., Schlosshauer B., Stuermer C. A. The spatiotemporal distribution of N-CAM in the retinotectal pathway of adult goldfish detected by the monoclonal antibody D3. Development. 108:1990;299-311.
16. Battisti W. P., Shinar Y., Schwartz M., Levitt P., Murray M. Temporal and spatial patterns of expression of laminin, chondroitin sulphate proteoglycan and HNK-1 immunoreactivity during regeneration in the goldfish optic nerve. J. Neurocytol. 21:1992;557-573.
17. Battisti W. P., Wang J., Bozek K., Murray M. Macrophages, microglia, and astrocytes are rapidly activated after crush injury of the goldfish optic nerve: A light and electron microscopic analysis. J. Comp. Neurol. 354:1995;306-320.
18. Beck K. D., Valverde J., Alexi T., Poulsen K., Moffat B., Vandlen R. A., Rosenthal A., Hefti F. Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain. Nature. 373:1995;339-341.
19. Becker C. G., Becker T., Bernhardt R. R., Schachner M. Regenerating descending axons in the zebrafish spinal cord avoid myelinated tracts. Soc. Neurosci. Abstr. 23:1997;1727.
20. Becker D. L., Cook J. E. Divergent axon collaterals in the regenerating goldfish optic tract: A fluorescence double-label study. Development. 104:1988;317-320.
21. Becker T., Bernhardt R. R., Reinhard E., Wullimann M. F., Tongiorgi E., Schachner M. Readiness of zebrafish brain neurons to regenerate a spinal axon correlates with differential expression of specific recognition molecules. J. Neurosci. 18:1998;5789-5803.
22. Becker T., Wullimann M. F., Becker C. G., Bernhardt R. R., Schachner M. Axonal regrowth after spinal cord transection in adult zebrafish. J. Comp. Neurol. 377:1997;577-595.
23. Benfey M., Buenger U., Vidal-Sanz M., Bray G. M., Aguayo A. J. Axonal regeneration from GABAergic neurons in the rat thalamus. J. Neurocytol. 14:1985;279-296.
24. Benowitz L. I., Routtenberg A. GAP-43: An intrinsic determinant of neuronal development and plasticity. Trends Neurosci. 20:1997;84-91.
25. Bernhardt R. Axonal pathfinding during the regeneration of the goldfish optic pathway. J. Comp. Neurol. 284:1989;119-134.
26. Bernhardt R., Easter S. S. Jr. Map of retinal position onto the cross section of the optic pathway of goldfish. J. Comp. Neurol. 254:1986;493-510.
27. Bernhardt R., Easter S. S. Jr. Regenerated optic fibers in goldfish reestablish a crude sectoral order in the visual pathway. J. Comp. Neurol. 277:1988;403-419.
28. Bernhardt R., Easter S. S. Jr., Raymond P. A. Axons added to the regenerated visual pathway of goldfish establish a normal fiber topography along the age-axis. J. Comp. Neurol. 277:1988;420-429.
29. Bernhardt R. R. Ipsi- and contralateral commissural growth cones react differently to the cellular environment of the ventral zebrafish spinal cord. J. Comp. Neurol. 350:1994;122-132.
30. Bernhardt R. R. Cellular and molecular bases of axonal pathfinding in the developing central nervous system of fish. J. Neurobiol. 38:1999;137-160.
31. Bernhardt R. R., Tongiorgi E., Anzini P., Schachner M. Increased expression of specific recognition molecules by retinal ganglion cells and by optic pathway glia accompanies the successful regeneration of retinal axons in adult zebrafish. J. Comp. Neurol. 376:1996;253-264.
32. Bernstein J. J. Relation of spinal cord regeneration to age in adult goldfish. Exp. Neurol. 9:1964;161-174.
33. Bernstein J. J. Successful spinal cord regeneration: Known biological strategies. Reier P. J., Bunge R. P., Seil F. J. Current Issues in Neural Regeneration Research. 1988;331-341 Liss, New York.
34. Blaugrund E., Lavie V., Cohen I., Solomon A., Schreyer D. J., Schwartz M. Axonal regeneration is associated with glial migration: Comparison between the injured optic nerves of fish and rats. J. Comp. Neurol. 330:1993;105-112.
35. Bregman B. S., Kunkel-Bagden E., Schnell L., Dai H. N., Gao D., Schwab M. E. Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors. Nature. 378:1995;498-501.
36. Brennan C., Monschau B., Lindberg R., Guthrie B., Drescher U., Bonhoeffer F., Holder N. Two Eph receptor tyrosine kinase ligands control axon growth and may be involved in the creation of the retinotectal map in the zebrafish. Development. 124:1997;655-664.
37. Bruemmendorf T., Rathjen F. G. Axonal glycoproteins with immunoglobulin- and fibronectin type III-related domains in vertebrates: Structural features, binding activities, and signal transduction. J. Neurochem. 61:1993;1207-1219.
38. Bruemmendorf T., Rathjen F. G. Cell adhesion molecules. 1. Immunoglobulin superfamily. Protein Profile. 1:1994;951-1058.
39. Buchanan J. T. Lamprey spinal interneurons and their roles in swimming activity. Brain Behav. Evol. 48:1996;287-296.
40. Buffo A., Holtmaat A. J. D. G., Savio T., Verbeek J. S., Oberdick J., Oestreicher A. B., Gipsen W. H., Verhaagen J., Rossi F., Strata P. Targeted overexpression of the neurite growth-associated protein B-50/GAP-43 in cerebellar Purkinje cells induces sprouting after axotomy but not axon regeneration into growth-permissive transplants. J. Neurosci. 17:1997;8778-8791.
41. Bunt S. M. Retinotopic and temporal organization of the optic nerve and tracts in the adult goldfish. J. Comp. Neurol. 206:1982;209-226.
42. Bunt S. M., Fill Moebs P. Selection of pathways by regenerating spinal cord fiber tracts. Brain Res. 318:1984;307-311.
43. Caroni P., Schwab M. E. Two membrane protein fractions from rat central myelin with inhibitory properties for neurite growth and fibroblast spreading. J. Cell Biol. 106:1988;1281-1288.
44. Cellerino A., Kohler K. Brain-derived neurotrophic factor/neurotrophin-4 receptor TrkB is localized on ganglion cells and dopaminergic amacrine cells in the vertebrate retina. J. Comp. Neurol. 386:1997;149-160.
45. Cenni M. C., Bonfanti L., Martinou J. C., Ratto G. M., Strettoi E., Maffei L. Long-term survival of retinal ganglion cells following optic nerve section in adult bcl-2 transgenic mice. Eur. J. Neurosci. 8:1996;1735-1745.
46. Cheng H., Cao Y., Olson L. Spinal cord repair in paraplegic rats: Partial restoration of hindlimb function. Science. 273:1996;510-513.
47. Chong M. S., Reynolds M. L., Irwin N., Coggeshall R. E., Emson P. C., Benowitz L. I., Woolf C. J. GAP-43 expression in primary sensory neurons following central axotomy. J. Neurosci. 14:1994;4375-4384.
48. Coggeshall R. E., Birse S. G., Youngblood C. S. Recovery from spinal transection in fish. Neurosci. Lett. 32:1982;259-264.
49. Coggeshall R. E., Youngblood C. S. Recovery from spinal transection in fish: Regrowth of axons past the transection. Neurosci. Lett. 38:1983;227-231.
50. Cohen A. H., Baker M. T. Functional and non-functional regeneration in the spinal cord of adult lampreys. Reier P. J., Bunge R. P., Seil F. J. Current Issues in Neural Regeneration Research. 1988;387-396 Liss, New York.
51. Cohen A. H., Mackler S. A., Selzer M. E. Functional regeneration following spinal transection demonstrated in the isolated spinal cord of the larval sea lamprey. Proc. Natl. Acad. Sci. USA. 83:1986;2763-2766.
52. Cohen I., Shani Y., Schwartz M. Cloning and characteristics of fish glial fibrillary acidic protein: Implications for optic nerve regeneration. J. Comp. Neurol. 334:1993;431-443.
53. Cohen I., Sivron T., Lavie V., Blaugrund E., Schwartz M. Vimentin immunoreactive glial cells in the fish optic nerve: Implications for regeneration. Glia. 10:1994;16-29.
54. Cook J. E., Becker D. L. Retinotopic refinement of the regenerating goldfish optic tract is not linked to activity-dependent refinement of the retinotectal map. Development. 104:1988;321-329.
55. Dahl D., Bignami A. Immunochemical and immunofluorescence studies of the glial fibrillary acidic protein in vertebrates. Brain Res. 61:1973;279-293.
56. Davis G. R. Jr., McClellan A. D. Extent and time course of restoration of descending brainstem projections in spinal cord-transected lamprey. J. Comp. Neurol. 344:1994;65-82.
57. Doherty P., Walsh F. S. Signal transduction events underlying neurite outgrowth stimulated by cell adhesion molecules. Curr. Opin. Neurobiol. 4:1994;49-55.
58. Doster S. K., Lozano A. M., Aguayo A. J., Willard M. B. Expression of the growth-associated protein GAP-43 in adult rat retinal ganglion cells following axon injury. Neuron. 6:1991;635-647.
59. Dowding A. J., Maggs A., Scholes J. Diversity amongst the microglia in growing and regenerating fish CNS: Immunohistochemical characterization using FL.1, an anti-macrophage monoclonal antibody. Glia. 4:1991;345-364.
60. Drescher U., Bonhoeffer F., Muller B. K. The Eph family in retinal axon guidance. Curr. Opin. Neurobiol. 7:1997;75-80.
61. Druger R. K., Glasgow E., Fuchs C., Levine E. M., Matthews J. P., Park C. Y., Schechter N. Complex expression of keratins in goldfish optic nerve. J. Comp. Neurol. 340:1994;269-280.
62. Eisele L. E., Schmidt J. T. Activity sharpens the regenerating retinotectal projection in goldfish: Sensitive period for strobe illumination and lack of effect on synaptogenesis and on ganglion cell receptive field properties. J. Neurobiol. 19:1988;395-411.
63. Eitan S., Schwartz M. A transglutaminase that converts interleukin-2 into a factor cytotoxic to oligodendrocytes. Science. 261:1993;106-108.
64. Eitan S., Solomon A., Lavie V., Yoles E., Hirschberg D. L., Belkin M., Schwartz M. Recovery of visual response of injured adult rat optic nerves treated with transglutaminase. Science. 264:1994;1764-1768.
65. Eitan S., Zisling R., Cohen A., Belkin M., Hirschberg D. L., Lotan M., Schwartz M. Identification of an interleukin 2-like substance as a factor cytotoxic to oligodendrocytes and associated with central nervous system regeneration. Proc. Natl. Acad. Sci. USA. 89:1992;5442-5446.
66. Flanagan J. G., Vanderhaeghen P. The ephrins and Eph receptors in neural development. Annu. Rev. Neurosci. 21:1998;309-345.
67. Friedman G. C., O'Leary D. D. Eph receptor tyrosine kinases and their ligands in neural development. Curr. Opin. Neurobiol. 6:1996;127-133.
68. Frisen J., Yates P. A., McLaughlin T., Friedman G. C., O'Leary D. D., Barbacid M. Ephrin-A5 (AL-1/RAGS) is essential for proper axon guidance and topographic mapping in the mammalian visual system. Neuron. 20:1998;235-243.
69. Fuchs C., Druger R. K., Glasgow E., Schechter N. Differential expression of keratins in goldfish optic nerve during regeneration. J. Comp. Neurol. 343:1994;332-340.
70. Gaze R. M. The Formation of Nerve Connections. 1970;Academic Press, London.
71. Giehl K. M., Tetzlaff W. BDNF and NT-3, but not NGF, prevent axotomy-induced death of rat corticospinal neurons in vivo. Eur. J. Neurosci. 8:1996;1167-1175.
72. Giordano S., Glasgow E., Tesser P., Schechter N. A type II keratin is expressed in glial cells of the goldfish visual pathway. Neuron. 2:1989;1507-1516.
73. Giordano S., Hall C., Quitschke W., Glasgow E., Schechter N. Keratin 8 of simple epithelia is expressed in glia of the goldfish nervous system. Differentiation. 44:1990;163-172.
74. Giordano S., Laessing U., Ankerhold R., Lottspeich F., Stuermer C. A. Molecular characterization of E587 antigen: An axonal recognition molecule expressed in the goldfish central nervous system. J. Comp. Neurol. 377:1997;286-297.
75. Gotz R., Koster R., Winkler C., Raulf F., Lottspeich F., Schartl M., Thoenen H. Neurotrophin-6 is a new member of the nerve growth factor family. Nature. 372:1994;266-269.
76. Grafstein B. The goldfish visual system as a model for the study of regeneration in the central nervous system. Cronly-Dillon J. R. Development and Plasticity of the Visual System. 1991;190-205 Macmillan & Co. London.
77. Grillner S., Wallen P., Brodin L. Neuronal network generating locomotor behavior in lamprey: circuitry, transmitters, membrane properties, and stimulation. Annu. Rev. Neurosci. 14:1991;169-199.
78. Hallbook F., Lundin L. G., Kullander K. Lampetra fluviatilis neurotrophin, descendant of a neurotrophin ancestor, discloses the early molecular evolution of neurotrophins in the vertebrate subphylum. J. Neurosci. 18:1998;8700-8711.
79. Hanna G. F. B., Nawar S. C., Sharma S. C. Regeneration of ascending spinal axons in goldfish. Brain Res. 791:1998;235-245.
80. Hashimoto M., Heinrich G. Brain-derived neurotrophic factor gene expression in the developing zebrafish. Int. J. Dev. Neurosci. 15:1997;983-997.
81. Hatten M. E., Liem R. K., Shelanski M. L., Mason C. A. Astroglia in CNS injury. Glia. 4:1991;233-243.
82. Herdegen T., Bastmeyer M., Bahr M., Stuermer C., Bravo R., Zimmermann M. Expression of JUN, KROX, and CREB transcription factors in goldfish and rat retinal ganglion cells following optic nerve lesion is related to axonal sprouting. J. Neurobiol. 24:1993;528-543.
83. Herdegen T., Skene P., Baehr M. The c-Jun transcription factor - bipotential mediator of neuronal death, survival and regeneration. Trends Neurosci. 20:1997;227-231.
84. Hirsch S., Cahill M. A., Stuermer C. A. Fibroblasts at the transection site of the injured goldfish optic nerve and their potential role during retinal axonal regeneration. J. Comp. Neurol. 360:1995;599-611.
85. Holder N., Clarke J. D. Is there a correlation between continuous neurogenesis and directed axon regeneration in the vertebrate nervous system. Trends Neurosci. 11:1988;94-99.
86. Hopkins J. M., Ford Holevinski T. S., McCoy J. P., Agranoff B. W. Laminin and optic nerve regeneration in the goldfish. J. Neurosci. 5:1985;3030-3038.
87. Hynes R. O. Integrins: Versatility, modulation, and signaling in cell adhesion. Cell. 69:1992;11-25.
88. Jacobs A. J., Swain G. P., Snedeker J. A., Pijak D. S., Gladstone L. J., Selzer M. E. Recovery of neurofilament expression selectively in regenerating reticulospinal neurons. J. Neurosci. 17:1997;5206-5220.
89. Jacobson M. Developmental Neurobiology. 1993;Plenum, New York.
90. Jeserich G., Waehneldt T. V. Bony fish myelin: Evidence for common major structural glycoproteins in central and peripheral myelin of trout. J. Neurochem. 46:1986;525-533.
91. Jessell T. M. Adhesion molecules and the hierarchy of neural development. Neuron. 1:1988;3-13.
92. Johns P. R. Growth of the adult goldfish eye. III. Source of new ganglion cells. J. Comp. Neurol. 176:1977;343-358.
93. Kanki J. P., Chang S., Kuwada J. Y. The molecular cloning and characterization of potential chick DM-GRASP homologs in zebrafish and mouse. J. Neurobiol. 25:1994;831-845.
94. Keynes R. J., Cook G. M. Repulsive and inhibitory signals. Curr. Opin. Neurobiol. 5:1995;75-82.
95. Kimmel C. B. Reticulospinal and vestibulospinal neurons in the young larva of a teleost fish. Brachydanio rerio. Prog. Brain. Res. 57:1982;1-23.
96. Kow J., Janzen R., Wong C., Levine R. L. On the guidance of regenerating axons from a half-retina in the adult goldfish. Exp. Neurol. 124:1993;299-307.
97. Kuwada J. Y., Bernhardt R. R., Nguyen N. Development of spinal neurons and tracts in the zebrafish embryo. J. Comp. Neurol. 302:1990;617-628.
98. Laessing U., Giordano S., Stecher B., Lottspeich F., Stuermer C. A. Molecular characterization of fish neurolin: A growth-associated cell surface protein and member of the immunoglobulin superfamily in the fish retinotectal system with similarities to chick protein DM-GRASP/SC-1/BEN. Differentiation. 56:1994;21-29.
99. Laessing U., Stuermer C. A. Spatiotemporal pattern of retinal ganglion cell differentiation revealed by the expression of neurolin in embryonic zebrafish. J. Neurobiol. 29:1996;65-74.
100. Lai K. O., Fu W. Y., Ip F. C., Ip N. Y. Cloning and expression of a novel neurotrophin, NT-7, from carp. Mol. Cell. Neurosci. 11:1998;64-76.
101. Lang D. M., Monzon-Mayor M., Bandtlow C. E., Stuermer C. A. O. Retinal axon regeneration in the lizard Gallotia gallotti in the presence of CNS myelin and oligodendrocytes. Glia. 23:1998;61-74.
102. Lang D. M., Rubin B. P., Schwab M. E., Stuermer C. A. CNS myelin and oligodendrocytes of the Xenopus spinal cord - but not optic nerve - are nonpermissive for axon growth. J. Neurosci. 15:1995;99-109.
103. Lanners H. N., Grafstein B. Early stages of axonal regeneration in the goldfish optic tract: An electron microscopic study. J. Neurocytol. 9:1980;733-751.
104. Li Y., Field P. M., Raisman G. Repair of adult corticospinal tract by transplants of olfactory ensheathing cells. Science. 277:1997;2000-2002.
105. Lieberman A. R. The axon reaction. Int. Rev. Neurobiol. 14:1971;49-124.
106. Lowenger E., Levine R. L. Studies of the early stages of optic axon regeneration in the goldfish. J. Comp. Neurol. 271:1988;319-330.
107. Lurie D., Selzer M. E. Pathfinding by regenerating axons in the lamprey spinal cord. Reier P. J., Bunge R. P., Seil F. J. Current Issues in Neural Regeneration Research. 1988;369-385 Liss, New York.
108. Maggs A., Scholes J. Glial domains and nerve fiber patterns in the fish retinotectal pathway. J. Neurosci. 6:1986;424-438.
109. Maggs A., Scholes J. Reticular astrocytes in the fish optic nerve: Macroglia with epithelial characteristics form an axially repeated lacework pattern, to which nodes of Ranvier are apposed. J. Neurosci. 10:1990;1600-1614.
110. Marcus R. C., Easter S. S. Jr. Expression of glial fibrillary acidic protein and its relation to tract formation in embryonic zebrafish (Danio rerio). J. Comp. Neurol. 359:1995;365-381.
111. Martin G. F., Ghooray G. T., Wang X. M., Xu X. M., Zou X. C. Models of spinal cord regeneration. Prog. Brain Res. 103:1994;175-201.
112. Martini R., Schachner M. Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and myelin-associated glycoprotein) in regenerating adult mouse sciatic nerve. J. Cell Biol. 106:1988;1735-1746.
113. McClellan A. D. Functional regeneration and restoration of locomotor activity following spinal cord transection in lamprey. Prog. Brain Res. 103:1994;203-217.
114. McKerracher L., David S., Jackson D. L., Kottis V., Dunn R. J., Braun P. E. Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth. Neuron. 13:1994;805-811.
115. McMillian M. K., Thai L., Hong J. S., O'Callaghan J. P., Pennypacker K. R. Brain injury in a dish: A model for reactive gliosis. Trends Neurosci. 17:1994;138-142.
116. McQuarrie I. G., Grafstein B. Protein synthesis and fast axonal transport in regenerating goldfish retinal ganglion cells. Brain Res. 235:1982;213-223.
117. Merline M., Kalil K. Cell death of corticospinal neurons is induced by axotomy before but not after innervation of spinal targets. J. Comp. Neurol. 296:1990;506-516.
118. Merrick S. E., Pleasure S. J., Lurie D. I., Pijak D. S., Selzer M. E., Lee V. M. Glial cells of the lamprey nervous system contain keratin-like proteins. J. Comp. Neurol. 355:1995;199-210.
119. Meyer R. Mapping the normal and regenerating retinotectal projection of goldfish with autoradiographic methods. J. Comp. Neurol. 189:1980;273-289.
120. Meyer R. L. Tetrodotoxin inhibits the formation of refined retinotopography in goldfish. Brain. Res. 282:1983;293-298.
121. Meyer R. L., Sakurai K., Schauwecker E. Topography of regenerating optic fibers in goldfish traced with local wheat germ injections into retina: Evidence for discontinuous microtopography in the retinotectal projection. J. Comp. Neurol. 239:1985;27-43.
122. Misantone L. J., Gershenbaum M., Murray M. Viability of retinal ganglion cells after optic nerve crush in adult rats. J. Neurocytol. 13:1984;449-465.
123. Morrow D. R., Campbell G., Lieberman A. R., Anderson P. N. Differential regenerative growth of CNS axons into tibial and peroneal nerve grafts in the thalamus of adult rats. Exp. Neurol. 120:1993;60-69.
124. Nicholls J., Saunders N. Regeneration of immature mammalian spinal cord after injury. Trends Neurosci. 19:1996;229-234.
125. Nieto M. A. Molecular biology of axon guidance. Neuron. 17:1996;1039-1048.
126. Nilsson A. S., Fainzilber M., Falck P., Ibanez C. F. Neurotrophin-7: A novel member of the neurotrophin family from the zebrafish. FEBS Lett. 13:1998;285-290.
127. Nona S. N., Shehab S. A., Stafford C. A., Cronly Dillon J. R. Glial fibrillary acidic protein (GFAP) from goldfish: Its localisation in visual pathway. Glia. 2:1989;189-200.
128. Nona S. N., Stafford C. A. Glial repair at the lesion site in regenerating goldfish spinal cord: An immunohistochemical study using species-specific antibodies. J. Neurosci. Res. 42:1995;350-356.
129. Nona S. N., Stafford C. A., Duncan A., Cronly Dillon J. R., Scholes J. Myelin repair by Schwann cells in the regenerating goldfish visual pathway: Regional patterns revealed by X-irradiation. J. Neurocytol. 23:1994;400-409.
130. Paschke K. A., Lottspeich F., Stuermer C. A. Neurolin, a cell surface glycoprotein on growing retinal axons in the goldfish visual system, is reexpressed during retinal axonal regeneration. J. Cell Biol. 117:1992;863-875.
131. Pawson T., Bernstein A. Receptor tyrosine kinases: Genetic evidence for their role in Drosophila and mouse development. Trends Genet. 6:1990;350-356.
132. Pueschel A. W. The semaphorins: A family of axonal guidance molecules. Eur. J. Neurosci. 8:1996;1317-1321.
133. Quitschke W., Schechter N. Homology and diversity between intermediate filament proteins of neuronal and nonneuronal origin in goldfish optic nerve. J. Neurochem. 46:1986;545-555.
134. Rankin E. C., Cook J. E. Topographic refinement of the regenerating retinotectal projection of the goldfish in standard laboratory conditions: A quantitative WGA-HRP study. Exp. Brain Res. 63:1986;409-420.
135. Rathjen F. G., Jessell T. M. Glycoproteins that regulate the growth and guidance of vertebrate axons: Domains and dynamics of the immunoglobulin type III family. Semin. Neurosci. 3:1991;297-307.
136. Raymond P. A., Easter S. S. Jr. Postembryonic growth of the optic tectum in goldfish. I. Location of germinal cells and numbers of neurons produced. J. Neurosci. 3:1983;1077-1091.
137. Raymond P. A., Easter S. S. Jr., Burnham J. A., Powers M. K. Postembryonic growth of the optic tectum in goldfish. II. Modulation of cell proliferation by retinal fiber input. J. Neurosci. 3:1983;1092-1099.
138. Reichardt L. F., Tomaselli K. J. Extracellular matrix molecules and their receptors: Functions in neural development. Annu. Rev. Neurosci. 14:1991;531-570.
139. Reier P. J., Houlé J. D. The glial scar: Its bearing on axonal regeneration and transplantation approaches to CNS repair. Adv. Neurol. 47:1988;87-138.
140. Richardson P. M., Issa V. M., Aguayo A. J. Regeneration of long spinal axons in the rat. J. Neurocytol. 13:1984;165-182.
141. Ridet J. L., Malhorta S. K., Privat A., Gage F. H. Reactive astrocytes: Cellular and molecular cues to biological function. Trends Neurosci. 20:1997;570-577.
142. Rossi F., Jankovsky A., Sotelo C. Differential regenerative response of Purkinje cell and inferior olivary axons confronted with embryonic grafts: Environmental cues versus intrinsic neuronal determinants. J. Comp. Neurol. 359:1995;663-677.
143. Rusoff A. C., Easter S. S. Jr. Order in the optic nerve of goldfish. Science. 208:1980;311-312.
144. Salles F. J., Schechter N., Strickland S. A plasminogen activator is induced during goldfish optic nerve regeneration. EMBO J. 9:1990;2471-2477.
145. Sandell J. H., Martin S. C., Heinrich G. The development of neurotrophin receptor Trk immunoreactivity in the retina of zebrafish (Brachydanio rerio). Brain Res. Dev. Brain Res. 81:1994;192-200.
146. Sanner C. A., Cunningham T. J., Goldberger M. E. NMDA receptor blockade rescues Clarke's and red nucleus neurons after spinal hemisection. J. Neurosci. 14:1994;6472-6480.
147. Sauvé Y., Sawai H., Rasminsky M. Functional synaptic connections made by regenerated retinal ganglion cell axons in the superior colliculus of adult hamsters. J. Neurosci. 15:1995;665-675.
148. Schachner M. Neuronal recognition molecules and their influence on cellular functions. Letourneau P. C., Kater S. B., Macagno E. R. The Nerve Growth Cone. 1992;237-254 Raven Press, New York.
149. Schaefer M., Fruttiger M., Montag D., Schachner M., Martini R. Disruption of the gene for the myelin-associated glycoprotein improves axonal regrowth along myelin in C57BL/Wlds mice. Neuron. 16:1996;1107-1113.
150. Schmidt J. T., Buzzard M. Activity-driven sharpening of the regenerating retinotectal projection: Effects of blocking or synchronizing activity on the morphology of individual regenerating arbors. J. Neurobiol. 21:1990;900-917.
151. Schmidt J. T., Edwards D. L. Activity sharpens the map during the regeneration of the retinotectal projection in goldfish. Brain Res. 269:1983;29-39.
152. Scholes J. J. Nerve fiber topography in the retinal projection to the tectum. Nature. 278:1979;620-624.
153. Schreyer D. J., Skene J. H. Fate of GAP-43 in ascending spinal axons of DRG neurons after peripheral nerve injury: Delayed accumulation and correlation with regenerative potential. J. Neurosci. 11:1991;3738-3751.
154. Schuch U., Lohse M. J., Schachner M. Neural cell adhesion molecules influence second messenger systems. Neuron. 3:1989;13-20.
155. Schwab M. E., Bartholdi D. Degeneration and regeneration of axons in the lesioned spinal cord. Physiol. Rev. 76:1996;319-370.
156. Schwab M. E., Kapfhammer J. P., Bandtlow C. E. Inhibitors of neurite growth. Annu. Rev. Neurosci. 16:1993;565-595.
157. Schwalb J. M., Boulis N. M., Gu M. F., Winickoff J., Jackson P. S., Irwin N., Benowitz L. I. Two factors secreted by the goldfish optic nerve induce retinal ganglion cells to regenerate axons in culture. J. Neurosci. 15:1995;5514-5525.
158. Schwalb J. M., Gu M. F., Stuermer C., Bastmeyer M., Hu G. F., Boulis N., Irwin N., Benowitz L. I. Optic nerve glia secrete a low-molecular-weight factor that stimulates retinal ganglion cells to regenerate axons in goldfish. Neuroscience. 72:1996;901-910.
159. Sharma S. C., Jadhao A. G., Rao P. D. Regeneration of supraspinal projection neurons in the adult goldfish. Brain Res. 620:1993;221-228.
160. Sivron T., Schwab M. E., Schwartz M. Presence of growth inhibitors in fish optic nerve myelin: Postinjury changes. J. Comp. Neurol. 343:1994;237-246.
161. Sivron T., Schwartz M. Glial cell types, lineages, and response to injury in rat and fish: Implications for regeneration. Glia. 13:1995;157-165.
162. Skene J. H. Axonal growth-associated proteins. Annu. Rev. Neurosci. 12:1989;127-156.
163. Skene J. H., Willard M. Changes in axonally transported proteins during axon regeneration in toad retinal ganglion cells. J. Cell Biol. 89:1981;86-95.
164. Sperry R. W. Chemoaffinity in the orderly growth of nerve fiber patterns and connections. Proc. Natl. Acad. Sci. USA. 50:1963;703-710.
165. Springer A. D. Normal and abnormal retinal projections following the crush of one optic nerve in goldfish (Carassius auratus). J. Comp. Neurol. 199:1981;87-95.
166. Springer A. D., Heacock A. M., Schmidt J. T., Agranoff B. W. Bilateral tectal innervation by regenerating optic nerve fibers in goldfish: A radioautographic, electrophysiological and behavioral study. Brain Res. 128:1977;417-427.
167. Springer A. D., Mednick A. S. Topography of the goldfish optic tracts: Implications for the chronological clustering model. J. Comp. Neurol. 239:1985;108-116.
168. Springer A. D., Mednick A. S. Retinotopic and chronotopic organization of goldfish retinal ganglion cell axons throughout the optic nerve. J. Comp. Neurol. 247:1986;221-232.
169. Springer A. D., Morel K. D., Wilson B. R. Topographic disorganization of the optic tracts following long-term optic nerve regeneration: A quantitative image analysis study. J. Comp. Neurol. 298:1990;458-471.
170. Springer A. D., Wilson B. R. Light microscopic study of degenerating cobalt-filled optic axons in goldfish: Role of microglia and radial glia in debris removal. J. Comp. Neurol. 282:1989;119-132.
171. Stafford C. A., Shehab S. A., Nona S. N., Cronly Dillon J. R. Expression of glial fibrillary acidic protein (GFAP) in goldfish optic nerve following injury. Glia. 3:1990;33-42.
172. Stelzner D. J., Bohn R. C., Strauss J. A. Expansion of the ipsilateral retinal projection in the frog brain during optic nerve regeneration: Sequence of reinnervation and retinotopic organization. J. Comp. Neurol. 201:1981;299-317.
173. Stratmann A., Jeserich G. Molecular cloning and tissue expression of a cDNA encoding IP1 - a P0-like glycoprotein of trout CNS myelin. J. Neurochem. 64:1995;2427-2436.
174. Strobel G., Stuermer C. A. Growth cones of regenerating retinal axons contact a variety of cellular profiles in the transected goldfish optic nerve. J. Comp. Neurol. 346:1994;435-448.
175. Stuermer C. A. Pathways of regenerated retinotectal axons in goldfish. I. Optic nerve, tract and tectal fascicle layer. J. Embryol. Exp. Morphol. 93:1986;1-28.
176. Stuermer C. A. Trajectories of regenerating retinal axons in the goldfish tectum. I. A comparison of normal and regenerated axons at late regeneration stages. J. Comp. Neurol. 267:1988;55-68.
177. Stuermer C. A. Trajectories of regenerating retinal axons in the goldfish tectum. II. Exploratory branches and growth cones on axons at early regeneration stages. J. Comp. Neurol. 267:1988;69-91.
178. Stuermer C. A., Bastmeyer M., Bahr M., Strobel G., Paschke K. Trying to understand axonal regeneration in the CNS of fish. J. Neurobiol. 23:1992;537-550.
179. Stuermer C. A., Easter S. S. Jr. A comparison of the normal and regenerated retinotectal pathways of goldfish. J. Comp. Neurol. 223:1984;57-76.
180. Takeichi M. Cadherin cell adhesion receptors as a morphogenetic regulator. Science. 251:1991;1451-1455.
181. Taylor J. S. H., Gaze R. M. The induction of an anomalous ipsilateral projection in Xenopus laevis. Anat. Embryol. 181:1990;393-404.
182. Tesser P., Jones P. S., Schechter N. Elevated levels of retinal neurofilament mRNA accompany optic nerve regeneration. J. Neurochem. 47:1986;1235-1243.
183. Tessier-Lavigne M. Eph receptor tyrosine kinases, axon repulsion, and the development of topographic maps. Cell. 82:1995;345-348.
184. Tessier-Lavigne M., Goodman C. S. The molecular biology of axon guidance. Science. 274:1996;1123-1133.
185. Tetzlaff W., Kobayashi N. R., Giehl K. M., Tsui B. J., Cassar S. L., Bedard A. M. Response of rubrospinal and corticospinal neurons to injury and neurotrophins. Prog. Brain Res. 103:1994;271-286.
186. Thanos S. Adult retinofugal axons regenerating through a peripheral nerve graft can restore the light-induced pupilloconstriction reflex. Eur. J. Neurosci. 13:1992;455-466.
187. Thanos S., Naskar A., Heiduschka P. Regenerating ganglion cell axons in the adult rat establish retinofugal topography and restore visual function. Exp. Brain Res. 114:1997;483-491.
188. Tongiorgi E., Bernhardt R. R., Schachner M. Zebrafish neurons express two L1-related molecules during early axonogenesis. J. Neurosci. Res. 42:1995;547-561.
189. van der Geer P., Hunter T., Lindberg R. A. Receptor protein-tyrosine kinases and their signal transduction pathways. Annu. Rev. Cell Biol. 10:1994;251-337.
190. van Raamsdonk W., Maslam S., de Jong D. H., Smit-Onel M. J., Velzing E. Long term effects of spinal cord transection in zebrafish: Swimming performances, and metabolic properties of the neuromuscular system. Acta Histochem. 100:1998;117-131.
191. van Raamsdonk W., Smit-Onel M. J., Maslam S., Velzing E., de Heus R. Changes in the synaptology of spinal motoneurons in zebrafish following spinal cord transection. Acta Histochem. 100:1998;133-148.
192. Vaudano E., Campbell G., Anderson P. N., Davies A. P., Woolhead C., Schreyer D. J., Lieberman A. R. The effects of a lesion or a peripheral nerve graft on GAP-43 upregulation in the adult rat brain: An in situ hybridization and immunocytochemical study. J. Neurosci. 15:1995;3594-3611.
193. Vidal-Sanz M., Bray G. M., Villegas Perez M. P., Thanos S., Aguayo A. J. Axonal regeneration and synapse formation in the superior colliculus by retinal ganglion cells in the adult rat. J. Neurosci. 7:1987;2894-2909.
194. Vielmetter J., Lottspeich F., Stuermer C. A. The monoclonal antibody E587 recognizes growing (new and regenerating) retinal axons in the goldfish retinotectal pathway. J. Neurosci. 11:1991;3581-3593.
195. Vielmetter J., Stuermer C. A. Goldfish retinal axons respond to position-specific properties of tectal cell membranes in vitro. Neuron. 2:1989;1331-1339.
196. Vielmetter J., Walter J., Stuermer C. A. Regenerating retinal axons of goldfish respond to a repellent guiding component on caudal tectal membranes of adult fish and embryonic chick. J. Comp. Neurol. 311:1991;321-329.
197. Wanner M., Lang D. M., Bandtlow C. E., Schwab M. E., Bastmeyer M., Stuermer C. A. Reevaluation of the growth-permissive substrate properties of goldfish optic nerve myelin and myelin proteins. J. Neurosci. 15:1995;7500-7508.
198. Wilm C., Fritsch B. Ipsilateral retinofugal projections in a percomorph bony fish: Their experimental induction, specificity and maintenance. Brain Behav. Evol. 36:1990;271-299.
199. Wilm C., Fritsch B. Ipsilateral retinal projections into the tectum during regeneration of the optic nerve in the cichlid fish Haplochromis burtoni: A DiI study in fixed tissue. J. Neurobiol. 23:1992;692-707.
200. Wilson S. W., Easter S. S. Jr. A pioneering growth cone in the embryonic zebrafish brain. Proc. Natl. Acad. Sci. USA. 88:1991;2293-2296.
201. Wilson S. W., Easter S. S. Jr. Stereotyped pathway selection by growth cones of early epiphysial neurons in the embryonic zebrafish. Development. 112:1991;723-746.
202. Xu X. M., Martin G. F. The response of rubrospinal neurons to axotomy in the adult opossum. Didelphis virginiana. Exp. Neurol. 108:1990;46-54.
203. Zhang Y., Campbell G., Anderson P. N., Martini R., Schachner M., Lieberman A. R. Molecular basis of interactions between regenerating adult rat thalamic axons and Schwann cells in peripheral nerve grafts. I. Neural cell adhesion molecules. J. Comp. Neurol. 361:1995;193-209.
204. Zottoli S. J., Bentley A. P., Feiner D. G., Hering J. R., Prendergast B. J., Rieff H. I. Spinal cord regeneration in adult goldfish: Implications for functional recovery in vertebrates. Prog. Brain Res. 103:1994;219-228.