Efficient enzymatic synthesis of amide with (aminomethyl)trimethylsilane

Journal of Bioscience and Bioengineering

Volumn 87, Issue 5, 1999, Pages 607-610

  Kawamoto, Takuo ^a   So, Rosario S ^a,b   Masuda, Yoshihisa ^a   Tanaka, Atsuo ^a  

^a KYOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF THE PHILIPPINES LOS BAÑOS   (Philippines)

Author keywords

(aminomethyl)trimethylsilane; 2,2 dimethylpropylamine; Amide formation; Hydrolase; Silicon containing amine

Indexed keywords

AMIDE; HYDROLASE; ORGANOSILICON DERIVATIVE; TRIMETHYLSILYL DERIVATIVE;

ARTICLE; CATALYSIS; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; SYNTHESIS;

EID: 0032975981     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1389-1723(99)80122-4     Document Type: Article

References (8)

1. 1. Colvin, E. W.: Silicon in organic synthesis. Butterworths, London (1981).
2. 2. Tacke, R. and Zilch, H.: Sila-substitution: a useful strategy for drug design? Endeavour New Series, 10, 191-197 (1986).
3. 3. Rioci, A., Seconi, G., and Taddei, M.: Bioorganosilicon chemistry: trends and perspectives. Chemicaoggi, 7, 15-21 (1989).
4. 4. Kawamoto, T., Sonomoto, K., and Tanaka, A.: Efficient optical resolution of 2-(4-chlorophenoxy)propanoic acid with lipase by the use of organosilicon compounds as substrate: the role of silicon atom in enzymatic recognition. J. Biotechnol., 18, 85-92 (1991).
5. 5. Tanaka, A., Fukui, T., Uejima, A., Zong, M.-H., and Kawamoto, T.: Bioconversion of nonnatural organic compounds: esterification and dehydrogenation of organosilicon compounds. Ann. N.Y. Acad. Sci., 672, 431-435 (1992).
6. 6. Tanaka, A., Fukui, T., and Kawamoto, T.: Enantioselective bioconversion of non-natural compounds. Biocatalysis, 9, 343-353 (1994).
7. 7. Tanaka, A. and Kawamoto, T.: Organosilicon biochemistry. Chemicaoggi, 7/8, 63-69 (1994).
8. 8. Kawamoto, T., Yamanaka, H., and Tanaka, A.: Enzymatic preparation of optically active silicon-containing amino acids and their application. Appl. Biochem. Biotechnol. (1999). (in press)