메뉴 건너뛰기




Volumn 88, Issue 3, 1999, Pages 640-647

Pharmacokinetics and pharmacokinetic-dynamic relationship between rapacuronium (Org 9487) and its 3-desacetyl metabolite (Org 9488)

Author keywords

[No Author keywords available]

Indexed keywords

3 DESACETYLRAPACURONIUM; MUSCLE RELAXANT AGENT; RAPACURONIUM BROMIDE; UNCLASSIFIED DRUG;

EID: 0032975279     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-199903000-00032     Document Type: Article
Times cited : (40)

References (17)
  • 1
    • 0027272272 scopus 로고
    • Time course of action and endotracheal intubating conditions of Org 9487, a new short-acting steroidal muscle relaxant: A comparison with succinylcholine
    • Wierda JMKH, Van den Broek L, Proost JH, et al. Time course of action and endotracheal intubating conditions of Org 9487, a new short-acting steroidal muscle relaxant: a comparison with succinylcholine. Anesth Analg 1993;77:579-84.
    • (1993) Anesth Analg , vol.77 , pp. 579-584
    • Wierda, J.M.H.1    Van Den Broek, L.2    Proost, J.H.3
  • 2
    • 0030910025 scopus 로고    scopus 로고
    • Dose-ranging study in younger adult and elderly patients of Org 9487, a new, rapidonset, short duration muscle relaxant
    • Kahwaji R, Bevan DR, Bikhazi G, et al. Dose-ranging study in younger adult and elderly patients of Org 9487, a new, rapidonset, short duration muscle relaxant. Anesth Analg 1997;84: 1011-8.
    • (1997) Anesth Analg , vol.84 , pp. 1011-1018
    • Kahwaji, R.1    Bevan, D.R.2    Bikhazi, G.3
  • 3
    • 0031463755 scopus 로고    scopus 로고
    • Comparison of vecuronium with Org 9487 and their interaction
    • Schiere S, Van den Broek L, Proost JH, et al. Comparison of vecuronium with Org 9487 and their interaction. Can J Anaesth 1997;44:1138-43.
    • (1997) Can J Anaesth , vol.44 , pp. 1138-1143
    • Schiere, S.1    Van Den Broek, L.2    Proost, J.H.3
  • 4
    • 0028025287 scopus 로고
    • Pharmacodynamics and pharmacokinetics of an infusion of Org 9487, a new short-acting steroidal neuromuscular blocking agent
    • Van den Broek L, Wierda JMKH, Smeulers NJ, Proost JH. Pharmacodynamics and pharmacokinetics of an infusion of Org 9487, a new short-acting steroidal neuromuscular blocking agent. Br J Anaesth 1994;73:331-5.
    • (1994) Br J Anaesth , vol.73 , pp. 331-335
    • Van Den Broek, L.1    Wierda, J.M.H.2    Smeulers, N.J.3    Proost, J.H.4
  • 5
    • 0344033964 scopus 로고
    • Onset of action of relaxants
    • Donati F. Onset of action of relaxants. Can J Anaesth 1988;35: S52-8.
    • (1988) Can J Anaesth , vol.35
    • Donati, F.1
  • 6
    • 0008626138 scopus 로고
    • Structure-pharmacokinetic and pharmacodynamic relationships of steroidal neuromuscular blocking agents
    • Fukushima K, Ochiai R, eds. Tokyo: Springer-Verlag
    • Proost JH, Wierda JMKH, Meijer DKF. Structure-pharmacokinetic and pharmacodynamic relationships of steroidal neuromuscular blocking agents. In: Fukushima K, Ochiai R, eds. Muscle relaxants: physiologic and pharmacologie aspects. Tokyo: Springer-Verlag, 1995:205-12.
    • (1995) Muscle Relaxants: Physiologic and Pharmacologie Aspects , pp. 205-212
    • Proost, J.H.1    Wierda, J.M.H.2    Meijer, D.K.F.3
  • 7
    • 0018394195 scopus 로고
    • Simultaneous modeling of pharmacokinetics and pharmacodynamics: Application to d-tubocurarine
    • Sheiner LB, Stanski DR, Vozeh S, et al. Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine. Clin Pharmacol Ther 1979;25:358-71.
    • (1979) Clin Pharmacol Ther , vol.25 , pp. 358-371
    • Sheiner, L.B.1    Stanski, D.R.2    Vozeh, S.3
  • 8
    • 0027502947 scopus 로고
    • The relaxometer: A complete and comprehensive computercontrolled neuromuscular transmission measurement system developed for clinical research on muscle relaxants
    • Rowaan CJ, Vandenbrom RHG, Wierda JMKH. The relaxometer: a complete and comprehensive computercontrolled neuromuscular transmission measurement system developed for clinical research on muscle relaxants. J Clin Monit 1993;9:38-44.
    • (1993) J Clin Monit , vol.9 , pp. 38-44
    • Rowaan, C.J.1    Vandenbrom, R.H.G.2    Wierda, J.M.H.3
  • 9
    • 0026764712 scopus 로고
    • Muscle relaxants of the future
    • Bevan DR, Donati F. Muscle relaxants of the future. Semin Anesth 1992;! 1:123-30.
    • (1992) Semin Anesth , vol.1 , pp. 123-130
    • Bevan, D.R.1    Donati, F.2
  • 11
    • 0022592133 scopus 로고
    • Comparative pharmacokinetics and dynamics of vecuronium and pancuronium in anesthetized patients
    • Sohn YJ, Bencini AF, Scaf AHJ, et al. Comparative pharmacokinetics and dynamics of vecuronium and pancuronium in anesthetized patients. Anesth Analg 1986;65:233-9.
    • (1986) Anesth Analg , vol.65 , pp. 233-239
    • Sohn, Y.J.1    Bencini, A.F.2    Scaf, A.H.J.3
  • 12
    • 0025825844 scopus 로고
    • The pharmacodynamics and pharmacokinetics of Org 9426, a new nondepolarizing neuromuscular blocking agent, in patients anaesthetized with nitrous oxide, halothane and fentanyl
    • Wierda JMKH, Kleef UW, Lambalk LM, et al. The pharmacodynamics and pharmacokinetics of Org 9426, a new nondepolarizing neuromuscular blocking agent, in patients anaesthetized with nitrous oxide, halothane and fentanyl. Can J Anaesth 1991;38:430-5.
    • (1991) Can J Anaesth , vol.38 , pp. 430-435
    • Wierda, J.M.H.1    Kleef, U.W.2    Lambalk, L.M.3
  • 13
    • 0030877478 scopus 로고    scopus 로고
    • Relationship between chemical structure and physicochemical properties of series of bulky organic cations and their hepatic uptake and biliary excretion rates
    • Proost JH, Roggeveld J, Wierda JMKH, Meijer DKF. Relationship between chemical structure and physicochemical properties of series of bulky organic cations and their hepatic uptake and biliary excretion rates. J Pharmacol Exp Ther 1997;282: 715-26.
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 715-726
    • Proost, J.H.1    Roggeveld, J.2    Wierda, J.M.H.3    Meijer, D.K.F.4
  • 14
    • 0022474424 scopus 로고
    • Hepatobiliary disposition of vecuronium bromide in man
    • Bencini AF, Scaf AH], Sohn YJ, et al. Hepatobiliary disposition of vecuronium bromide in man. Br J Anaesth 1986;58:988-95.
    • (1986) Br J Anaesth , vol.58 , pp. 988-995
    • Bencini, A.F.1    Scaf, A.H.2    Sohn, Y.J.3
  • 15
    • 0025212614 scopus 로고
    • The neuromuscular blocking effects and pharmacokinetics of Org 9426 and Org 9616 in the cat
    • Khuenl-Brady KS, Castagnoli KP, Canfell PC, et al. The neuromuscular blocking effects and pharmacokinetics of Org 9426 and Org 9616 in the cat. Anesthesiology 1990;72:669-74.
    • (1990) Anesthesiology , vol.72 , pp. 669-674
    • Khuenl-Brady, K.S.1    Kp, C.2    Canfell, P.C.3
  • 16
    • 0028301486 scopus 로고
    • Pharmacokinetics and pharmacokinetic/dynamic relationship of rocuronium bromide in humans
    • Wierda JMKH, Proost JH, Schiere S, Hommes FDM. Pharmacokinetics and pharmacokinetic/dynamic relationship of rocuronium bromide in humans. Eur J Anaesthesiol 1994;11(Suppl 9):66-74.
    • (1994) Eur J Anaesthesiol , vol.11 , Issue.9 SUPPL. , pp. 66-74
    • Wierda, J.M.H.1    Proost, J.H.2    Schiere, S.3    Hommes, F.D.M.4
  • 17
    • 0031057256 scopus 로고    scopus 로고
    • Pharmacodynamics and pharmacokinetics of rocuronium in intensive care patients
    • Sparr HJ, VVierda JMKH, Proost JH, et al. Pharmacodynamics and pharmacokinetics of rocuronium in intensive care patients. Br J Anaesth 1997;78:267-73.
    • (1997) Br J Anaesth , vol.78 , pp. 267-273
    • Sparr, H.J.1    Vvierda, J.M.H.2    Proost, J.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.