The importance of keratin 18 in breast cancer;Zur klinischen bedeutung von keratin 18 beim mammakarzinom

Zentralblatt fur Gynakologie

Volumn 121, Issue 3, 1999, Pages 126-130

  Schaller, Gerhard ^a   Fuchs, Ilka ^b   Ebert, A ^b   Gstettenbauer, M ^b   Herbst, H ^b   Lengyel, E ^b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b NONE

Author keywords

Breast cancer; Keratin 18; Metastases

Indexed keywords

KERATIN;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER MORTALITY; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; FEMALE; HUMAN; MAJOR CLINICAL STUDY; PREDICTION; PROGNOSIS; PROTEIN STRUCTURE; STATISTICAL ANALYSIS; TUMOR DIAGNOSIS;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; FEMALE; FOLLOW-UP STUDIES; HUMANS; KERATINS; LYMPHATIC METASTASIS; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RECURRENCE; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; TIME FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 0032975183     PISSN: 00444197     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Baribault H, Price J, Miyai K, Oshima RG: Mid-gestational lethality in mice lacking keratin 8. Gene Dev 7 (1993) 1191-1202
2. Breslow NE, Day NE: Statistical Methods in Cancer Research. WHO, International Agency for Research on Cancer. 2 (1987)
3. Geisler N, Kaufmann E, Weber K: Antiparallel Orientation of the Two Double-stranded Coiled-coils in the Tetrameric Protofilament unit of Intermediate Filaments. J Mol Biol 182 (1985) 173-177
4. Jarasch ED, Nagle R, Kaufmann M, Maurer C, Böcker W: Differential Diagnosis of benign epithelial proliferations and carcinomas of the breast using antibodies to cytokeratins. Hum Pathol 3 (1988) 276-289
5. Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Stat Ass 53 (1958) 457-481
6. Kreis Th, Vale R: Guidebook to the Cytoskeletal and Motor Proteins. Oxford University Press 1993
7. Lawless, JF: Statistical Models and Methods for Lifetime Data. John Wiley & Sons 1982, 484-485
8. Lichtner RB, Julian JA, North SM, Glasser SR, Nicolson GL: Coexpression of Cytokeratins Characteristic for Myoepthelial and Luminal Cell Lineages in Rat 13762NF Mammary Adenocarcinoma Tumors and Their Spontaneous Metastases. Cancer Res 51 (1991) 5943-5950
9. Mc Cann AH, Dervan PA, O'Regan M, Codd MB, Gullick WJ, Tobin BMJ Carney DN: Prognostic Significance of c-erbB-2 and Estrogen Receptor Status in Human Breast Cancer. Cancer Res 51 (1991) 3296-3303
10. Moll R, Franke W, Schiller D: The Catalog of human cytokeratins: patterns of expression in normal epithelia, tumours and cultured cells. Cell 31 (1982) 11-24
11. Moll R, Zimbelmann R, Goldschmidt MD, Keith M, Laufer J, Kasper M, Koch PJ, Franke WW: The human gene encoding cytokeratin 20 and its expression during fetal development and in gastrointestinal carcinomas. Differentiation 53 (1993) 75-93
12. Moll R: Cytokeratine als Differenzierungsmarker: Expressionsprofile von Epithelien und epithelialen Tumoren. Stuttgart: Gustav Fischer Verlag 1993
13. Nakamura Y: Cleaning up on b-Catenin. Nature Medicine 3 (1997) 499-500
14. Pankov R, Umezawa A, Maki R, Der CJ, Hauser CA, Oshima RG: Oncogene activation of human keratin 18 transcription via the Ras signal transduction. Proc Natl Acad Sci USA 91 (1994) 873-877
15. Pankov R, Neznanov N, Umezawa A, Oshima RG: AP-1, ETS, and transcriptional silencers regulate retinoic acid-dependent induction of Keratin 18 in embryonic cells. Mol Cell Biol 14 (1994) 7744-7757
16. Remmele W, Stegner HE: Immunhistochemischer Nachweis von Östrogenrezeptoren (Er-ICA) im Mammakarzinomgewebe: Vorschlag zur einheitlichen Bewertung des Untersuchungsbefundes. Frauenarzt 2 (1987) 41
17. Schaller G, Genz Th: Immunohistochemical Detection of Keratins 1 and 13 as Differentiation Markers in the Hormone-Dependent Human Vaginal Epithelium. Gynecol Obstet Inves 30 (1990) 94-96
18. Schaller G, Fuchs I, Pritze W, Ebert A, Herbst H, Pantel K, Weitzel H, Lengyel E: Elevated Keratin 18 Expression Indicates a Favorable Prognosis in Patients with Breast Cancer. Clin Cancer Res 2 (1996) 1879-1885
19. Sun TT, Scheffer C, Tseng G, Huang AJW, Cooper D, Schermer A, Lynch MH, Weiss R, Eichner R: Monoclonal Antibody Studies of Mammalian Epithelial Keratins: A Review. Ann N Y Acad Sci (1985) 307-329
20. Tsubura A, Okada H, Senzaki H, Hatano T, Morii S: Keratin expression in the normal breast and in breast carcinoma. Histopathology 18 (1991) 517-522
21. Thompson EW, Paik S, Brunner N, Sommers CL, Zugmaier G, Clarke R, Shima TB, Torri J, Donahue S, Lippmann ME, Martin G, Dickson R: Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines. J Cell Physiol 150 (1992) 534-544
22. Trask DK, Band V, Zajchowski DA, Yaswen P, Suh T, Sager R: Keratins as markers that distinguish normal and tumor-derived mammary epithelial cells. Proc Natl Acad Sci USA 87 (1990) 2319-2323