Increased serotonin receptor density and platelet GPIIb/IIIa activation among smokers

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 19, Issue 3, 1999, Pages 762-766

  Markovitz, Jerome H ^a,c   Tolbert, Lelland ^b   Winders, Suzan E ^a  

^a UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Depression; Platelet activation; Serotonin receptors; Smoking; Thrombosis

Indexed keywords

FIBRINOGEN RECEPTOR; SEROTONIN 2A RECEPTOR;

ADULT; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CIGARETTE SMOKING; DEPRESSION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR DENSITY; RISK ASSESSMENT; THROMBOCYTE ACTIVATION;

EID: 0032974985     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.19.3.762     Document Type: Article

References (57)

1. Fielding JE. Smoking: health effects and control. New Engl J Med. 1985;313:491-498, 555-561.
2. Kannel WB, Neaton JD, Wentworth D, Thomas HE, Stamler J, Hulley SB, Kjelsberg MO. Overall and coronary heart disease mortality rates in relation to major risk factors in 325,348 men screened for the MRFIT. Multiple Risk Factor Intervention Trial. Am Heart J. 1986;112:825-836.
3. Weintraub WS. Cigarette smoking as a risk factor for coronary artery disease. Adv Exp Med Biol. 1990;273:27-37.
4. Kimura S, Nishinaga M, Ozawa T, Shimada K. Thrombin generation as an acute effect of cigarette smoking. Am Heart J. 1994;128:7-11.
5. Smith FB, Lowe GD, Fowkes FG, Rumley A, Rumley AG, Donnan PT, Housley E. Smoking, haemostatic factors and lipid peroxides in a population case control study of peripheral arterial disease. Atherosclerosis. 1993;102:155-162.
6. Folsom AR. Epidemiology of fibrinogen. Eur Heart J. 1995;16(suppl A):21-23.
7. Folts JD, Bonebrake FC. The effects of cigarette smoke and nicotine on platelet thrombus formation in stenosed dog coronary arteries: inhibition with phentolamine. Circulation. 1982;65:465-470.
8. Bolli R, Ware JA, Brandon TA, Willacher DG, Mace ML. Platelet mediated thrombosis in stenosed canine coronary arteries: inhibition by a platelet-active alpha-adrenergic antagonist. J Am Coll Cardiol. 1984;3: 1417-1426.
9. Folts JD, Gering SA, Laibly SW, Bertha BG, Bonebrake FC, Keller JW. Effects of cigarette smoke and nicotine on platelets and experimental coronary artery thrombosis. In: Diana JN, ed. Tobacco Smoking and Atherosclerosis. New York: Plenum Press; 1990:339-358.
10. Davis JW, Arnold J. Time course of some effects of cigarette smoking on platelets. J Intern Med. 1992;231:31-36.
11. Blache D, Bouthillier D, Davignon J. Acute influence of smoking on platelet behavior, endothelium and plasma lipids and normalization by aspirin. Atherosclerosis. 1992;93:179-188.
12. Foo LC, Roshidah I, Aimy MB. Platelets of habitual smokers have reduced susceptibility to aggregating agents. Thromb Haemost. 1991;65: 317-319.
13. Ozdemir O, Karaaslan Y, Ozcebe O, Dundar S, Kirazli S. The acute effect of smoking on platelet and endothelial release reaction is suppressed in chronic smokers. Thromb Res. 1992;65:263-274.
14. Benowitz NL, Fitzgerald GA, Wilson M, Zhang Q. Nicotine effects on ecosanoid formation and hemostatic function: comparison of transdermal nicotine and cigarette smoking. J Am Coll Cardiol. 1993;22:1159-1167.
15. Pfueller SL, Burns P, Mak K, Firkin BG. Effects of nicotine on platelet function. Haemostasis. 1988;18:163-169.
16. Rival J, Riddle JM, Stein PD. Effects of chronic smoking on platelet function. Thromb Res. 1987;45:75-85.
17. Winniford MD, Wheelan KR, Kremers MS, Ugolini V, van den Berg E Jr, Niggemann H, Jansen DE, Hillis LD. Smoking-induced coronary vasoconstriction in patients with atherosclerotic coronary artery disease: evidence for adrenergically mediated alterations in coronary artery tone. Circulation. 1986;73:662-667.
18. Cryer PE, Haymond MW, Santiago JV, Shah SD. Norepinephrine and epinephrine release and adrenergic mediation of smoking-associated hemodynamic and metabolic events. New Engl J Med. 1976;295:573-577.
19. 2-receptors and serotonin release: their role in human platelet aggregation. Life Sci. 1993;53:209-215.
20. 2 receptor on human platelets. Life Sci. 1987;40:1799-1809.
21. Sparrow D, O'Connor GT, Young JB, Rosner B, Weiss ST. Relationship of urinary serotonin excretion to cigarette smoking and respiratory symptoms: the Normative Aging Study. Chest. 1992;101:976-980.
22. Racke K, Schworer H, Simson G. Effects of cigarette smoking or ingestion of nicotine on platelet 5-hydroxytryptamine (5-HT) levels in smokers and non-smokers. Clin Invest. 1992;70:201-204.
23. Marasini B, Biondi ML, Barbesti S, Zatta G, Agostoni A. Cigarette smoking and platelet function. Thromb Res. 1986;44:85-94.
24. Benwell ME, Balfour DJ, Anderson JM. Smoking-associated changes in the serotonergic systems of discrete regions of human brain. Psychopharmacology. 1990;102:68-72.
25. Potter WZ, Manji HK. Catecholamines in depression: an update. Clin Chem. 1994;40:279-287.
26. Biegon A, Israeli M, Elizur A, Bruch S, Bar-Nathan AA. Serotonin 5-HT2 receptor binding on blood platelets as a state dependent marker in major affective disorder. Psychopharmacology. 1990;102:73-75.
27. 3H]lysergic acid diethylamide binding to a 5-hydroxytryptamine receptor on human platelet membranes. Eur J Pharmacol. 1984;97: 87-93.
28. Pandey GN, Pandey SC, Janicak PG, Marks RC, Davis JM. Platelet serotonin-2 receptor, binding sites in depression and suicide. Biol Psychiatry. 1990;28:215-222.
29. Malone KM, Thase ME, Mieczkowski T, Myers JE, Stull SD, Cooper TB, Mann JJ. Fenfluramine challenge test as a predictor of outcome in major depression. Psychopharmacol Bull. 1993;29:155-161.
30. Anda RF, Williamson DF, Escobedo LG, Mast EE, Giovino GA, Remington PL. Depression and the dynamics of smoking, a national perspective. JAMA. 1990;264:1541-1545.
31. Glassman AH, Helzer JE, Covey LS, Cottler LB, Stetner F, Tipp JE, Johnson J. Smoking, smoking cessation, and major depression. JAMA. 1990;264:1546-1549.
32. Markovitz JH, Roubin GS, Parks JM, Bittner V. Platelet activation and restenosis following coronary stenting: flow cytometric detection of wound-induced platelet activation. Coron Artery Dis. 1996;7:657-665.
33. Markovitz JH, Kulkarni K, Goldschmidt-Clermont P, Kiefe CI, Rustagi P, Sekar P, Nanda N. Increased platelet activation and fibrinogen in Asian Indians: potential implications for coronary risk. Eur Heart J. 1998;19: 720-726.
34. Markovitz JH. Hostility is associated with increased platelet activation in coronary heart disease. Psychosom Med. 1998;60:586-591.
35. Beck AT, Beamesderfer A. Assessment of depression: the depression inventory. In: Pinchot P, ed. Psychological Measurements in Psychopharmacology. Vol 7. Basel: Karger; 1974:151-169.
36. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the folin phenol reagent. J Biol Chem. 1951;193:265-275.
37. Burgisser E. Radioligand-receptor binding studies: what's wrong with the Scatchard analysis? Trends Pharmacol Sci. 1984;142-144.
38. Munson PJ. Experimental artifacts and the analysis of ligand binding data: results of a computer simulation. J Recept Res. 1983;3:249-259.
39. McFadden EP, Clanke JG, Davies GJ, Kaski JC, Haiden AW, Maseri A. Effect of intracoronary serotonin on coronary vessels in patients with stable angina and patients with variant angina. New Engl J Med. 1991; 324:648-654.
40. Russolillo E, Condorelli M, Chiariello M. Divergent effects of serotonin on coronary-artery dimensions and blood flow in patients with coronary atherosclerosis and control patients. N Engl J Med. 1991;324:641-648.
41. Crowley ST, Dempsey EC, Horwitz KB, Horwitz LD. Platelet-induced vascular smooth muscle cell proliferation is modulated by the growth amplification factors serotonin and adenosine diphosphate. Circulation. 1994;90:1908-1918.
42. Michelson AD. Flow cytometry: a clinical test of platelet function. Blood. 1996;87:4925-4936.
43. Sanderson HM, Heptinstall S, Vickers J, Losche W. Studies on the effects of agonists and antagonists on platelet shape change and platelet aggregation in whole blood. Blood Coagul Fibrinolysis. 1996;7:245-248.
44. Plow EF, Ginsberg MH. Cellular adhesion: GPIIb-IIIa as a prototypic adhesion receptor. Prog Hemost Thromb. 1989;9:117-156.
45. Coller, BS. Platelets and thrombolytic therapy. N Engl J Med. 1990;322: 33-42.
46. Weinhold LL, Stitzer ML. Effects of puff number and puff spacing on carbon monoxide exposure from commercial brand cigarettes. Pharmacol Biochem Behav. 1989;33:853-858.
47. Rubin R, Rand ML. Alcohol and platelet function. Alcohol Clin Exp Res. 1994;18:105-110.
48. Renaud S, DeLorgeril M. Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet. 1992;339:1523-1526.
49. Renaud S, Beswick Ad, Fehily AM, Sharp DS, Elwood PC. Alcohol and platelet aggregation: the Caerphilly prospective heart disease study. Am J Clin Nutr. 1992;55:1012-1017.
50. Zacny JP. Behavioral aspects of alcohol-tobacco interactions. Recent Dev Alcohol. 1990;8:205-219.
51. Henningfield JE, Clayton R, Pollin W. Involvement of tobacco in alcoholism and illicit drug use. Br J Addict. 1990;85:279-291.
52. Zeiher AM, Schachinger V, Minners J. Long-term cigarette smoking impairs endothelium-dependent coronary arterial vasodilator function. Circulation. 1995;92:1094-1100.
53. Lekakis J, Papamichael C, Vemmos C, Nanas J, Kontoyannis D, Stamatelopoulos S, Moulopoulos S. Effect of acute cigarette smoking on endothelium-dependent brachial artery dilatation in healthy individuals. Am J Cardiol. 1997;79:529-531.
54. Celermajer DS, Sorensen KE, Georgakopoulos D, Bull C, Thomas O, Robinson J, Deanfield JE. Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults. Circulation. 1993;88:2149-2155.
55. Freedman JE, Loscalzo J, Barnard MR, Alpert C, Keaney JF, Michelson AD. Nitric oxide released from activated platelets inhibits platelet recruitment. J Clin Invest. 1997;100:350-356.
56. Langford EJ, Wainwright RJ, Martin JF. Platelet activation in acute myocardial infarction and unstable angina is inhibited by nitric oxide donors. Arterioscler Thromb Vasc Biol. 1996;16:51-55.
57. Ichiki K, Ikeda H, Haramaki N, Ueno T, Imaizumi T. Long-term smoking impairs platelet-derived nitric oxide release. Circulation. 1996;94:3109-3114.