Toxicity of gamma irradiated liposomes. 1 In vitro interactions with blood components

International Journal of Pharmaceutics

Volumn 178, Issue 1, 1999, Pages 33-46

  Stensrud, G ^a   Passi, S ^a,b   Larsen, T ^a   Sandset, P M ^c   Smistad, G ^a   Monkkonen J ^b   Karlsen, J ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

Author keywords

Blood components; Gamma irradiation; Liposomes; Toxicity

Indexed keywords

CALCIUM; LIPOSOME; PHOSPHOLIPID;

ARTICLE; BLOOD CLOTTING; BLOOD COMPONENT; CONTROLLED STUDY; GAMMA RADIATION; HEMOLYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; THROMBOCYTE AGGREGATION;

BLOOD COAGULATION; CALCIUM; GAMMA RAYS; HEMOLYSIS; HUMANS; LIPOSOMES; PLATELET AGGREGATION; RADIATION;

EID: 0032974934     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(98)00356-1     Document Type: Article

References (40)

1. Albertini, G., Rustichelli, F., 1993. Effects of gamma irradiation on the liposomal structure. In: Gregoriadis, G. (Ed.), Liposome Technology; Liposomes preparation and related techniques, Vol. 1. CRC Press, Boca Raton, Ann Arbor, London, Tokyo, pp. 399-428.
2. Allen, T.M., 1993. Toxicity and systemic effects of phospholipids. In: Cevc, G. (Ed.), Phospholipid Handbook. Marcel Dekker, New York, Basel, Hong Kong, pp. 801-816.
3. Bonté F., Hsu M.J., Papp A., Wu K., Regen S.L., Juliano R.L. Interactions of polymerizable phosphatidylcholine vesicles with blood components: relevance to biocompatibility. Biochim. Biophys. Acta. 900:1987;1-9.
4. Cyrklaff M., Adrian M., Dubochet J. Evaporation during preparation of unsupported thin vitrified aqueous layers for cryo-electron microscopy. J. Electron Microsc. Tech. 16:1990;351-355.
5. Dubochet J., Adrian M., Chang J., Homo J., Lepault J., Mcdowall A., Schultz P. Cryo-electron microscopy of vitrified specimens. Q. Rev. Biophys. 21:1988;129-228.
6. Endres D.B., Rude R.K. Mineral and bone metabolism. J. Clin. Pharmacol. N.Y. Forts. AV J. Clin. Pharmacol. New Drugs. 29:1989;685-694.
7. Gottfried E.L., Rapport M.M. The biochemistry of plasmalogens: II, hemolytic activity of some plasmalogen derivatives. J. Lipid Res. 4:1963;57-62.
8. Grit M., Crommelin D.J.A. Chemical stability of liposomes: implications for their physical stability. Chem. Phys. Lipids. 64:1993;3-18.
9. Inoue K., Kitagawa T. Effects of exogenous lysolecithin on liposomal membranes: its relation to membrane fluidity. Biochim. Biophys. Acta. 363:1974;361-372.
10. Juliano R.L., Hsu M.J., Peterson D., Regen S.L., Singh A. Interactions of conventional or photopolymerized liposomes with platelets in vitro. Exp. Cell. Res. 146:1983;422-427.
11. Kobayashi T., Itabe H., Inoue K., Nojima S. Peroxidation of liposomes in the presence of human erythrocytes and induction of membrane damage of erythrocytes by peroxidized liposomes. Biochim. Biophys. Acta. 814:1985;170-178.
12. Kristensen S., Karlsen J., Tønnesen H.H. Photoreactivity of biologically active compounds, VI: photohaemolytical properties of antimalarias in vitro. Pharm. Sci. Commun. 4:1994;183-191.
13. Lüthje J., Ogilvie A. Platelet aggregation in whole blood: a laboratory experiment for a medical biochemistry course. Biochem. Ed. 15:1987;86-87.
14. Martin F.J., MacDonald R.C. Lipid vesicle-cell interactions, 1: hemagglutination and hemolysis. J. Cell Biol. 70:1976;494-505.
15. Miller I.F., Hoag J.M., Rooney M.W. On the interaction of the liposomal membrane with blood components. Biomat. Art. Cells Immob. Biotech. 20:1992;627-635.
16. New, R.R.C., 1990. Characterization of liposomes. In: New, R.R.C. (Ed.), Liposomes a Practical Approach. IRL press, Oxford, New York, Tokyo, pp. 105-161.
17. Papahadjopoulos D., Vail W.J., Pangborn W.A., Poste G. Studies om membrane fusion, II: induction of fusion in pure phospholipids membranes by calcium ions and other divalent metals. Biochim. Biophys. Acta. 448:1976;265-283.
18. Parnham M., Wetzig H. Toxicity screening of liposomes. Chem. Phys. Lipids. 64:1993;263-274.
19. Reid B.D. Gamma processing technology: an alternative technology for terminal sterilization of parenterals. PDA J. Pharm. Sci. Technol. 49:1995;83-89.
20. Reman F.C., Demel R.A., De Gier J., Van Deenen L.L.M., Eibl H., Westphal O. Studies on the lysis of red cells and bimolecular lipid leaflets by synthetic lysolecithins, lecithins and structural analogs. Chem. Phys. Lipids. 3:1969;221-233.
21. Schwarzenbach G. The complexones and their analytical application. Analyst. 80:1955;713-729.
22. Stark G. The effect of ionizing radiation on lipid membranes. Biochim. Biophys. Acta. 1071:1991;103-122.
23. Stensrud G., Smistad G., Karlsen J. Effects of gamma irradiation on the stability of liposomes/phospholipids, 1: chemical stability. Drug Stability. 1:1996;152-160.
24. Stensrud, G., Smistad, G., Ågren, T.L., Sande, S.A., Karlsen, J., 1997. Effects of gamma irradiation on the physical stability of liposomal phospholipids. J. Lipos. Res. 7, 503-528. Erratum; J. Lipos. Res. 8, 297-298, 1998.
25. Stensrud, G., Smistad, G., Ågren, T.L., Sande, S.A., Karlsen, J., 1997. Effects of gamma irradiation on the physical stability of liposomal phospholipids. J. Lipos. Res. 7, 503-528. Erratum; J. Lipos. Res. 8, 297-298, 1998.
26. Storm, G., Oussoren, C., Peeters, P.A.M., Barenholz, Y., 1993. Tolerability of Liposomes in vivo. In: Gregoriadis, G. (Ed.), Liposome Technology: Liposomes Preparation and Related Techniques, vol. 3. CRC Press, Boca Raton, Ann Arbor, London, Tokyo, pp. 345-383.
27. Tanaka Y., Mashino K., Inoue K., Nojima S. Mechanism of human erythrocyte hemolysis induced by short-chain phosphatidylcholines and lysophosphatidylcholine. J. Biochem. 94:1983;833-840.
28. Tinsley P.W., Maerker G. Effect of low-dose γ-radiation on individual phospholipids in aqueous suspension. JAOCS. 70:1993;187-191.
29. Weltzien H.U., Arnold B., Reuther R. Quantitative studies on lysolecithin-mediated hemolysis: use of ether-deoxy lysolecithin analogs with varying aliphatic chain-lengths. Biochim. Biophys. Acta. 466:1977;411-421.
30. Weltzien H.U. Cytolytic and membrane-perturbing properties of lysophosphatidylcholine. Biochim. Biophys. Acta. 559:1979;259-287.
31. Williams, W.J., 1983. Principles of coagulations tests. In: Williams, W.J., Beutler, E., Erslev, A.J., Lichtmann, M.A. (Eds.), Hematology. McGraw-Hill book company, New York, pp. 1257-1265.
32. Woods, R.J., Pikaev, A. K., 1994. Radiation sterilization of medical products. In: Woods, R.J., Pikaev, A.K. (Eds.), Applied Radiation Chemistry. John Wiley and Sons, New York, Chichester, Brisbane, Toronto, Singapore, pp. 401-403.
33. Yoshihara E., Nakae T. Cytolytic activity of liposomes containing stearylamine. Biochim. Biophys. Acta. 854:1986;93-101.
34. Zakrevsky V.I., Kubatiev A.A., Galaev Y.V. The effect of liposomal phospholipids on the collagen induced platelet aggregation. J. Lipos. Res. 4:1994;315-324.
35. Zbinden G., Wunderli-Allenspach H., Grimm L. Assessment of thrombogenic potential of liposomes. Toxicology. 54:1989;273-280.
36. Zuidam N.J., Lee S.S.L., Crommelin D.J.A. Sterilization of liposomes by heat treatment. Pharm. Res. 10:1993;1591-1596.
37. Zuidam N.J., Lee S.S.L., Crommelin D.J.A. Gamma-irradiation of non-frozen, frozen and freeze-dried liposomes. Pharm. Res. 12:1995;1761-1768.
38. Zuidam N.J., Versluis C., Vernooy E.A.A.M., Crommelin D.J.A. Gamma-irradiation of liposomes composed of saturated phospholipids, effect of bilayer composition, size, concentration and absorbed dose on chemical degradation and physical destabilization of liposomes. Biochim. Biophys. Acta. 1280:1996a;135-148.
39. Zuidam, N.J., Talsma, H., Crommelin, D.J.A., 1996b. Sterilization of liposomes. In: Barenholz, Y., Lasic, D.D. (Eds.), Nonmedical Application of Liposomes. CRC Press, Boca Raton, Ann Arbor, London, Tokyo, pp. 71-80.
40. Zwaal R.F.A. Membrane and lipid involvement in blood coagulation. Biochim. Biophys. Acta. 515:1978;163-205.